Hydrogen Isotope Exchange in 2-Butanone. Further Measurements and Some Comments
Keyword(s):
The ratio of rate constants for exchange at the methylene and methyl positions of butanone, [Formula: see text], is shown to be near 1.69 in 1:1 acetic acid–acetate buffer; nearly twice the value (0.86) for deuterioxide catalysis at 54.8°. Methods of obtaining rate constants for acetate catalysis from composite rates (acetate and deuterioxide), or from rates in buffered media, are shown to be adequate for estimating rate ratios.Detailed temperature dependence of the relative rate constants for either system is not yet available but the effects are known to be small. For butanone enolizations the isokinetic temperature is in the neighborhood of 35°, when reaction is catalyzed by deuterioxide in aqueous media.
1975 ◽
Vol 97
(22)
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pp. 6481-6483
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2009 ◽
Vol 45
(4)
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pp. 239-245
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1996 ◽
Vol 03
(01)
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pp. 655-660
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1960 ◽
Vol 38
(11)
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pp. 2187-2195
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2006 ◽
Vol 40
(2)
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pp. 201-211
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1974 ◽
Vol 29
(4)
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pp. 642-649
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