The Efficacy of Electroacupuncture Therapy for Weight Loss Changes Plasma Lipoprotein A, Apolipoprotein A and Apolipoprotein B Levels in Obese Women

In the present study, we aimed to investigate the effects of electroacupuncture treatment on lipoprotein A, apolipoprotein A and apolipoprotein B levels in obese subjects. Fifty-eight women were studied in 3 groups as follows: 1) Placebo acupuncture (n = 15; mean age = 41.47 ± 4.61, and mean body mass index {BMI} = 33.43 ± 3.10); 2) Electroacupuncture (EA) (n = 20; mean age = 40.55 ± 5.30, and BMI = 35.65 ± 3.84) and 3) Diet restriction groups (n = 23; mean age = 42.91 ± 4.02, and BMI = 34.78 ± 3.29). EA was performed using the ear points, Hungry, Shen Men and Stomach the body points, Hegu (LI 4), Quchi (LI 11), Tianshu (St 25), Zusanli (St 36), Neiting (St 44) and Taichong (Liv 3) for 20 days. Intragroup comparisons were made by using paired samples t-test whereas intergroup differences were investigated by the two-way variation analysis and LSD test. There was a 4.7% (p < 0.001) weight reduction in patients with electroacupuncture application, whereas patients in diet restriction had a 2.9% (p < 0.001) weight reduction. There were significant decreases in lipoprotein A (p < 0.05) and apolipoprotein B (p < 0.05) levels in the EA compared to the control group and no changes in apolipoprotein A levels was observed in EA, diet and placebo acupuncture groups. EA therapy may be a useful approach for the treatment of obesity for both losing weight and lowing the risk factors for cardiovascular disease associated with obesity, since this application may decrease the plasma lipoprotein A and apolipoprotein B levels.

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Electroacupuncture Therapy for Weight Loss Reduces Serum Total Cholesterol, Triglycerides, and LDL Cholesterol Levels in Obese Women

The American Journal of Chinese Medicine ◽

10.1142/s0192415x05003132 ◽

2005 ◽

Vol 33 (04) ◽

pp. 525-533 ◽

Cited By ~ 66

Author(s):

Mehmet Tuǧrul Cabıoǧlu ◽

Neyhan Ergene

Keyword(s):

Total Cholesterol ◽

Weight Reduction ◽

Ldl Cholesterol ◽

Density Lipoprotein ◽

The Body ◽

Serum Total Cholesterol ◽

Control Group ◽

Obese Women ◽

Diet Restriction ◽

Cholesterol Levels

Our purpose in this study was to investigate the effect of acupuncture therapy on body weight and on levels of the serum total cholesterol, triglyceride, high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol in obese women. Fifty-five women were studied in three groups as follows: (1) control group ( n = 12; mean age = 43.3 ± 4.3, and mean body mass index { BMI } = 32.2 ± 3.4); (2) electroacupuncture (EA) ( n = 22; mean age = 39.8 ± 5.3, and BMI = 34.8 ± 3.3); and (3) diet restriction ( n = 21; mean age = 42.7 ± 3.9, and BMI = 34.9 ± 3.3). EA was performed using the ear points, Sanjiao (Hungry) and Shen Men (Stomach), and the body points, LI 4, LI 11, St 25, St 36, St 44 and Liv 3, once daily, for 30 minutes, for 20 days, whereas patients on diet restriction had a 1425 Kcal diet program, that consisted of 1425 Kcal daily for 20 days. There was a 4.8% weight reduction in patients with EA application, whereas patients on diet restriction had a 2.5% weight reduction. There were significant decreases in total cholesterol and triglyceride levels in EA and diet groups compared with the control group ( p < 0.05 in both cases). Furthermore, there was a decrease in LDL levels in the EA group compared with the control group ( p < 0.05). No significant changes could be found in HDL levels among the three groups. Our results suggest that EA application in obese women may decrease the serum total cholesterol, triglyceride, and LDL cholesterol levels by increasing the serum beta endorphin level. This lipolytic effect of EA may also reduce the morbidity of obesity by mobilizing the energy stores that result in weight reduction.

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Fractional turnover of apolipoprotein(a) and apolipoprotein B-100 within plasma lipoprotein(a) particles in statin-treated patients with elevated and normal Lp(a) concentration

Metabolism ◽

10.1016/j.metabol.2019.04.010 ◽

2019 ◽

Vol 96 ◽

pp. 8-11 ◽

Cited By ~ 3

Author(s):

Louis Ma ◽

Dick C. Chan ◽

Esther M.M. Ooi ◽

P. Hugh R. Barrett ◽

Gerald F. Watts

Keyword(s):

Apolipoprotein B ◽

Plasma Lipoprotein ◽

Lipoprotein A ◽

Apolipoprotein A ◽

Fractional Turnover

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Changes in headache frequency in premenopausal obese women with migraine after bariatric surgery: A case series

Cephalalgia ◽

10.1177/0333102411413162 ◽

2011 ◽

Vol 31 (13) ◽

pp. 1336-1342 ◽

Cited By ~ 45

Author(s):

V Novack ◽

L Fuchs ◽

L Lantsberg ◽

S Kama ◽

U Lahoud ◽

...

Keyword(s):

Bariatric Surgery ◽

Weight Reduction ◽

Case Series ◽

Control Group ◽

Obese Women ◽

Specific Effects ◽

Migraine Frequency ◽

Reduced Frequency ◽

Causal Nature ◽

Post Bariatric Surgery

Background: The association between migraine and obesity gives the clinician with an exciting possibility to alleviate migraine suffering through weight-reduction gastric-restrictive operations. We hypothesized that bariatric weight-reduction intervention (gastric banding) will be associated with reduction of migraine burden in this population. Methods: A total of 105 women between 18 and 50 years of age, admitted for bariatric surgery between April 2006 and February 2007, were screened for migraine. Twenty-nine with diagnosis of migraine were enrolled into the prospective phase. We followed the migraine pattern of these patients for 6 months post bariatric surgery. Results: Baseline median migraine frequency was six headache days a month. Post bariatric surgery, the migraine-suffering women reported of a lower frequency of migraine attacks ( p < 0.001), shorter duration of the attacks ( p = 0.02), lower medication use during the attack ( p = 0.005), less non-migraine pain (44.8 vs. 33%, p = 0.05), and post-bariatric surgery reduction in headache-related disability assessed by the MIDAS and HIT-6 scores. There was a reduction in migraine frequency among both episodic (from four to one episodes a month) and chronic (from 16.8 to 8.5 episodes per month) migraine patient cohorts separately and combined. Conclusions: Among migraine-suffering premenopausal obese women, we found a reduced frequency of migraine attacks and improvement of headache-related disability post bariatric surgery. Our findings should be interpreted cautiously. The absence of a control group and the non-blinded nature of our small study make it difficult to draw firm conclusions about the causal nature of the headache changes observed in this population. Further study is needed to evaluate the possible specific effects of surgical weight loss on migraine in obese women.

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Modification of serum apolipoprotein A-I, apolipoprotein B and lipoprotein(a) levels after bisphosphonates-induced acute phase response

Clinica Chimica Acta ◽

10.1016/s0009-8981(97)00212-x ◽

1998 ◽

Vol 271 (1) ◽

pp. 79-87 ◽

Cited By ~ 31

Author(s):

Giuseppe Lippi ◽

Vania Braga ◽

Silvano Adami ◽

Giancesare Guidi

Keyword(s):

Acute Phase ◽

Apolipoprotein B ◽

Acute Phase Response ◽

Phase Response ◽

Lipoprotein A ◽

Apolipoprotein A

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Plasma lipoprotein(a) levels and expression of the apolipoprotein(a) gene are dependent on the nucleotide polymorphisms in its 5'-flanking region.

Journal of Clinical Investigation ◽

10.1172/jci119295 ◽

1997 ◽

Vol 99 (6) ◽

pp. 1361-1366 ◽

Cited By ~ 46

Author(s):

K Suzuki ◽

M Kuriyama ◽

T Saito ◽

A Ichinose

Keyword(s):

Plasma Lipoprotein ◽

Nucleotide Polymorphisms ◽

Lipoprotein A ◽

Apolipoprotein A ◽

Flanking Region

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SUPPLEMENTATION WITH 2:1 RATIO OF N-6:N-3 POLYUNSATURATED FATTY ACID IMPROVES LIVER STEATOSIS AND SERUM CYTOKINE LEVELS IN YOUNG OBESE BALINESE WOMEN: A RANDOMIZED CLINICAL TRIAL

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10i12.20851 ◽

2017 ◽

Vol 10 (12) ◽

pp. 74

Author(s):

I Wayan Weta ◽

Mahadewa Tjokorda Gb ◽

Wayan P Sutirtayasa ◽

Anak Agung Ngurah Subawa ◽

Safarina G Malik ◽

...

Keyword(s):

Fatty Acid ◽

Polyunsaturated Fatty Acid ◽

Body Fat ◽

Fat Body ◽

Liver Steatosis ◽

The Body ◽

Control Group ◽

Obese Women ◽

Pufa Ratio ◽

Tnf Α

Objectives: In addition to the rise in obesity prevalence globally, morbidity due to nonalcoholic fatty liver disease is increasing. Primary modalities for preventing and managing this problem include dietary modification and improved physical activities. A daily diet with a low n-6:n-3 polyunsaturated fatty acid (PUFA) ratio is suspected to contribute to ameliorating liver steatosis (LS). The present study was conducted to elucidate the effects of an n-6:n-3 PUFA ratio of 2:1 in alleviating LS.Methods: Twenty-four young obese women with LS were recruited from Denpasar, Bali, Indonesia. They were randomly allocated to an intervention or control group. Both groups were given linoleic acid:α-linolenic acid at ratios of 2035:970 and 240:100 g, respectively, for 12 weeks. Baseline and end-line data were obtained. All patients were advised to maintain their daily energy intake no more than 1500 kcal and to perform structured physical exercises once a week.Results: The intervention significantly decreased the body fat (body mass index, p=0.040; triglyceride, p=0.008) and serum tumor necrosis factor-α (TNF-α) levels (p=0.002) and increased serum interleukin-10 (IL-10) levels (p=0.004). The severity of LS was reduced through the intervention (odds ratio=0.064; 95% confidence interval=0.013-0.310; p=0.001).Conclusion: An increased intake of 2:1 n-6:n-3 PUFA ratio alleviated LS, decreased body fat composition and serum TNF-α levels, and increased serum IL-10 levels.

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