Magnetic manipulation on the unlabeled nonmagnetic particles

2019 ◽  
Vol 33 (07) ◽  
pp. 1950047 ◽  
Author(s):  
Yongqing He ◽  
Laan Luo ◽  
Shuang Huang

This paper reports two basic microfluidic strategies for the magnetic manipulation of unlabeled nonmagnetic particles/cells. One is the deflection induced by a single magnet, and the other is the confusing effect produced by two magnets of opposite polarity. They can be combined into more completed particle manipulations like continuous flow separation, counting and detection, which are essential steps in biomedical applications. We experimentally studied the dynamics of 10.4 and 20 [Formula: see text]m nonmagnetic polystyrene particles within a flow rate range of 30, 50, 70 and 90 [Formula: see text]L/min in a straight channel. We defined the cross-section length that the particles occupy as the “particle bandwidth” to characterize the extent of deflection and focusing. To predict the trajectories of the particles, we established a simple theoretical model by considering the magnetic force and viscous drag force. Compared with the experimental results, the maximum deviation of the simulation is 9.28%. The influences of magnetic nanoparticle concentration, magnetic field parameters, size of microparticles and flow rate are systematically investigated. We also demonstrated that the effective deflection and focusing could be realized at low Fe3O4 nanoparticle concentrations, which means that this method can reduce the damage on cells in the practical applications.

2021 ◽  
pp. 1-9
Author(s):  
Hao-tian Fan ◽  
Hong Li ◽  
Wei Mao ◽  
Yong-Jie Ding ◽  
Li-Qiu Wei ◽  
...  

2020 ◽  
Vol 213 ◽  
pp. 107511 ◽  
Author(s):  
Shan Ma ◽  
De-kang Xu ◽  
Wen-yang Duan ◽  
Ji-kang Chen ◽  
Kang-ping Liao ◽  
...  

Author(s):  
Shunya Takao ◽  
Kentarou Hayashi ◽  
Masahiro Miyabe

Abstract In order to improve suction performance, centrifugal pumps with an inducer are used for rocket pumps, liquid gas transport such as LNG, and general-purpose pumps. Since a higher suction performance than conventional pump is required, a splitter blade that consists of a long blade and a short blade is sometimes adopted. However, the design becomes more difficult due to the increased number of parameters. The stable operation over a wide flow rate range are required in the general-purpose pumps. Therefore it is necessary to design them so that unstable flow phenomena such as surges do not occur. However, the design method to avoid them is not well understood yet. In this study, we focused on the splitter blade impeller in a general-purpose low-speed centrifugal pump with an inducer. Six parameters such as leading edge position and trailing edge position of the short blade for both hub-side and tip-side were set as design ones. A multi-objective optimization method using a commercial software was applied to improve suction performance while maintaining high efficiency. Then obtained optimal shape were analyzed by CFD calculation and extracted the feature. Furthermore, optimized impellers were manufactured and confirmed the performance over a wide flow rate range by experiments. In addition, a optimizing design method that improves pump performance at lower cost was studied.


1998 ◽  
Vol 16 (1) ◽  
pp. 31-38 ◽  
Author(s):  
T. Kerdja ◽  
S. Abdelli ◽  
E. H. Amara ◽  
D. Ghobrini ◽  
M. Si-Bachir ◽  
...  

Time and space-resolved emission spectroscopy measurements were performed to investigate plasma dynamics during laser evaporation of a graphite target in an ambient inert atmosphere. Intense molecular emission is found to occur behind a front separating the plasma from the foreign gas. Two stages of expansion are found and are well described, using a viscous drag force model for the first one and a delayed ideal blast wave model for the second. The vibrational temperature estimated using the Swan band in helium at different pressures is presented.


2012 ◽  
Vol 220-223 ◽  
pp. 875-879
Author(s):  
Ying Xu ◽  
Cun Yin ◽  
Zheng Hai Long

In order to better simulate the flowing condition of wet gas, Tianjin University has designed and built up a wet gas flow experimental facility with adjustable and intermediate pressure in the flow laboratory. The designed pressure of the facility which used standard meter method and dual closed-loop design is 4MPa. The experiment medium is air and water, and the highest operation pressure is 1.6MPa. The gas flow rate range is 3~1000m3/h, and the liquid flow rate range is 0.05~8 m3/h. This article includes the structure introduction of the facility and the calculation of pressure loss of the system, etc. By the uncertainty assessment for the discussed facility, the conclusion is stated that the facility’s gas measurement uncertainty is 1% and the facility’s liquid measurement uncertainty is 0.35%.


Author(s):  
Uddalok Sen ◽  
Tryambak Gangopadhyay ◽  
Chandrachur Bhattacharya ◽  
Arpan Misra ◽  
Suman Karmakar ◽  
...  

Gas turbine combustion has a number of practical applications, including aviation engines, ocean vessels, and tanks. The various advantages of normal diffusion flames, such as increased flame stability and reduced susceptibility to dynamic instabilities, has made it the de facto industrial standard. However, high NOx emission and sooting from such flames is a major problem, particularly for heavier hydrocarbons fuels. In that regard, the inverse diffusion flame offers a feasible alternative; but the dynamic response of such a flame, particularly in ducted conditions — where the unsteady heat release interacts with the duct acoustics — is relatively less researched. In the present work, an experimental investigation of a laboratory-scale inverse diffusion flame has been carried out. The inverse diffusion flame is found in applications like rocket motors, gas turbine combustors, and furnaces. In the present study, inverse diffusion flame from a coaxial burner inside a quartz tube was studied. The position of the duct with respect to the flame was kept fixed, while the global equivalence ratio was varied by keeping the air flow rate constant and changing the fuel flow rate. Various tools of nonlinear dynamics such as phase space reconstruction and recurrence quantification have also been used for dynamic characterization of such flames. The results show that the dynamics of the flame strongly depends on the global equivalence ratio.


Soil Research ◽  
1973 ◽  
Vol 11 (2) ◽  
pp. 159 ◽  
Author(s):  
AC Bakker ◽  
WW Emerson

Beds of aggregates of Shepparton soil were leached with calcium chloride or magnesium chloride or with chloride solutions of given SAR with either calcium or magnesium as the complementary cation to bring the aggregates to a known ESP within the range 2.6-5.2. The last solution was 1 mM in the divalent cation. Water was then allowed to flow slowly through and the decrease in the flow rate measured. The permeability of aggregate beds washed with calcium or magnesium showed only a negligible decrease with time. With sodium present, the rate of decrease for a given ESP was faster the greater the initial flow rate of the water and also for smallersized aggregates. The ESP required to produce a given decrease in flow rate was reduced when magnesium was the complementary cation rather than calcium. The flow patterns are explained in terms of the rate of dispersion of clay from the aggregates in sympathy with the rate of loss of soluble salts, rather than detachment due to viscous drag. Four methods of measuring aggregate stability in water have been described in this series of papers. Their possible use to predict whether sodium in conjunction with magnesium will reduce water transmission through subsoils compared with similar calcium soils is discussed.


Author(s):  
Ding Tao ◽  
Yan Changqi ◽  
Cao Xiaxin ◽  
Guo Zehua

An experimental setup has been designed and fabricated for the analysis of filtration performance of the metal fiber filter as applied to Filtered Containment Venting System (FCVS). The main characteristic of this test facility is the presence of the aerosol and Scanning Mobility Particle Sizer. The objective is to investigate the removal performance of the metal fiber filter for aerosol, as well as further understand the filtration process in the metal fiber filter. It is observed that the metal fiber filter is capable of removing more than 99.955% aerosols at the desired flow rate ranging from 0.17 m/s to 0.3 m/s and the resistance has a significant linear correlation with flow rate. Due to the electrostatic effect, diffusion effect, inertia effect, interception effect and gravity effect, most penetrating particle size plays a significant role in removal performance of the metal fiber filter for aerosol. It is also found that with aerosol size ranging from 0.1 μ m to 0.3μm in most penetrating particle size, the filtration efficiency is more than 99.8% at the flow rate of 0.25 m/s. From this study, valuable reference data and useful information are provided for practical applications.


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