ESTIMATION OF LOW BONE MASS FOR THE ASSESSMENT OF OSTEOPOROSIS FRACTURE RISK IN INDIAN MEN AND WOMEN USING QUANTITATIVE ULTRASOUND AND DUAL ENERGY X-RAY ABSORPTIOMETRY

2004 ◽  
Vol 04 (01) ◽  
pp. 47-59 ◽  
Author(s):  
MALLIKARJUN S. HOLI ◽  
S. RADHAKRISHNAN

The objective of the present work is to estimate the prevalence of low bone mass in Indian men and women for the assessment of osteoporosis and fracture risk using quantitative ultrasound and dual energy X-ray absorptiometry (DEXA) and carryout a comparative evaluation for early prediction of osteoporosis. Data collected in this study is analyzed to assess the diagnostic performance of the ultrasound and how its performance compares to DEXA bone mineral density (BMD). Quantitative ultrasound assessment of osteoporosis is carried out by measuring broadband ultrasound attenuation (BUA) and speed of sound (SOS) through calcaneus bone to provide a clinical measure called the stiffness index (SI). The SI is a measure of bone density used to predict the risk of bone fracture due to osteoporosis. Bone mineral density (BMD) measurement is performed in lumbar region (L1–L4) of the spine in anterior-posterior direction using DEXA. In both studies the data is found to be significant in men and women subjects with p<0.0005 and percentage bone loss in men and women are significantly matching in both studies. Ultrasound performance correlates moderately well with DEXA (r=0.60 to 0.68) and provides comparable diagnostic sensitivity to spine BMD in predicting osteoporotic fractures.

Author(s):  
Sami P. Väänänen ◽  
Hanna Isaksson ◽  
Jukka S. Jurvelin

Measurement of bone mineral density (BMD) by DXA (dual-energy X-ray absorptiometry) is generally considered to be the clinical gold standard to diagnose osteoporosis. However, BMD alone is only a moderate predictor of fracture risk. Finite element analyses (FEA) of bone mechanics can contribute to a more accurate prediction of fracture risk (Cody et al. 1999). However, CT imaging is relatively expensive and inflicts larger radiation doses on the patient.


2018 ◽  
Vol 7 (2.8) ◽  
pp. 169
Author(s):  
U Snekhalatha ◽  
D Ashok Kumar ◽  
Padma Javasan

Background: Low bone mineral density increasing with age is a universally observed phenomenon. This leads to osteoporosis, which is a regressive change that occurs in the bone and it is diagnosed before the occurrence of fractures. The dual energy x -ray absorptiometry (DXA) is considered to be the standard measurement for the detection of bone mineral density (BMD).Objectives: To measure the various bone mass indices in the clavicle bone by radiogrammetric method from a posterior-to-anterior (PA) view of chest digital X-ray using semi- automated method.Methods: Forty women whose mean age was found to be 46.05±15.53 years were included in this study. For the total population (n=40), the right femur BMD was acquired by DXA scanner. The digital chest radiographs were taken for all the subjects. In all cases, the geometrical variables such as periosteal width (CLR-D), endosteal width (CLR-d), cortical thickness (CLR-CT) and percentage cortical thickness %(CLR-CT) were measured in the right clavicle bone region by semi-automated method approach developed in MATLAB software.Results: The CLR-CT (r=0.77) as well as with % CLR-CT (r=0.72) has provided statistically significant correlation (p < 0.01) with the total hip BMD in the total population studied. The pre-menopausal and post-menopausal of the studied population demonstrated a high significance value of (p < 0.01).Conclusion: The semi-automated measurement of low bone mass indices in clavicle radiogrammetry will be useful in the evaluation of low bone mass in post-menopausal women and elderly aged population. This method can be used as a screening tool for mass population, especially in rural India.


2000 ◽  
Vol 15 (11) ◽  
pp. 1847-1851 ◽  
Author(s):  
Mustafa Arici ◽  
Hakan Erturk ◽  
Bulent Altun ◽  
Celalettin Usalan ◽  
Sukru Ulusoy ◽  
...  

1997 ◽  
Vol 115 (6) ◽  
pp. 1580-1588 ◽  
Author(s):  
Marília Martins Silveira Marone ◽  
Cecília Helena de Azevedo Gouveia ◽  
Shlomo Lewin ◽  
Salim Wehba ◽  
Luiz Fernando Malvestiti ◽  
...  

AIMS:To investigate the influence of body weight (BW), fat mass (FM) and lean mass (LM) on the bone mineral density (BMD) of several areas of the skeleton. PARTICIPANTS: Sixty one white postmenopausal women (50.1±4.8 years). MEASUREMENTS: Measurement of BMD by dual energy x-ray absorptiometry. The results were analyzed by linear regression and the slopes of each curve were compared. RESULTS: The results showed that the correlations between BW, FM and LM to BMD were positive, whilst the correlations between age and years since menopause to BMD were negative. LM was the main factor that influenced BMD in almost all areas. CONCLUSIONS: FM and LM present a positive effect on BMD, although LM is the main determinant of bone mass. Moreover, higher values of LM and FM present a protective effect against the reduction of BMD combined with menopause. Therefore postmenopausal women with low BW, especially low LM, present serious risk for developing osteoporosis.


2015 ◽  
Vol 68 (9-10) ◽  
pp. 341-346
Author(s):  
Aleksandra Hadziavdic ◽  
Natasa Vajic ◽  
Nikola Gavric

Introduction. Osteoporosis is the most frequent metabolic disease of bones. Early detection of pathological loss of bone mineral density represents the first step in prevention, treatment and rehabilitation of osteoporosis. This study was aimed at establishing the correlation of T-score values obtained by ultrasound osteodensitometry of calcaneus with dual-energy x-ray absorptiometry scan. Material and Methods. The study was conducted on the sample of 569 female patients from September 13, 2010 to March 10, 2011. Measurement was made with ultrasound osteodensitometry of ACHILLES make. Quantitative ultrasound method revealed that 77 female patients had a lower value of T-score (osteopenia with risk factors or osteoporosis) and they were referred to T-score measurement with dual-energy x-ray absorptiometry scan. Dual-energy x-ray absorptiometry scanning was performed using LUNAR DPX scanner and 49 female patients were examined. Results. It was concluded that there was no statistically significant difference between T-score values obtained by quantitative ultrasound and dual-energy x-ray absorptiometry scanning. Conclusion. According to this study, it is necessary to provide a greater number of scanners for ultrasound osteodensitometry of calcaneus in order to secure prevention and to refer the patients to further diagnosing on time.


Proceedings ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 16
Author(s):  
Maryam Delshad ◽  
Kathryn L. Beck ◽  
Cathryn A. Conlon ◽  
Owen Mugridge ◽  
Marlena C. Kruger ◽  
...  

Background: Dual energy X-ray absorptiometry (DXA) is a well-regarded device for primarilymeasuring bone mineral density (BMD) and body composition. [...]


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