Design and modeling of microneedle integrated with microactuator for drug delivery

2014 ◽  
Vol 03 (03) ◽  
pp. 1450016
Author(s):  
K. Girija Sravani ◽  
Y. Srinivas ◽  
Bikash Swain ◽  
K. Sunil Banu ◽  
K. Srinivasa Rao
Keyword(s):  
Drug Delivery ◽  
Piezoelectric Actuator ◽  
Dimensional Stability ◽  
Blood Sampling ◽  
High Dimensional ◽  
Sampling Device ◽  
Metal Electrodes ◽  
New Model ◽  
Space Requirements ◽  
Manufacturing Time

Today's world has very much demand for the development of microscale devices, due to its less cost, space requirements, high-dimensional stability and especially manufacturing time. In this paper, we have design and simulated MEMS based microactuator and microneedle integration which will be very helpful for blood sampling device like e-mosquito. The dimensions of the modeled beam are of 100 mm long, 30 mm width, 10 mm thickness. This new design model consists of piezoceramic material sandwiched between two metal electrodes and the piezoelectric actuator is made with microneedle which will help for blood sampling purposes. The results after the simulation of this new model present that it will be suitable for blood sampling analysis with aluminum as electrodes and silicon as microneedle.

Implantable device for drug delivery and blood sampling in the rat

1985 ◽  
Vol 59 (5) ◽  
pp. 1665-1666
Author(s):  
J. F. Chester ◽  
S. A. Weitzman ◽  
R. A. Malt
Keyword(s):  
Drug Delivery ◽  
Polyvinyl Chloride ◽  
Implantable Device ◽  
Blood Sampling ◽  
Venous Sampling ◽  
Intravenous Catheter ◽  
Right Colon ◽  
Sampling Device ◽  
The Right

An implantable drug-delivery and venous sampling device is described that is constructed from a polyvinyl chloride catheter and a rubber intravenous catheter plug coated with Silastic. The implant was used for repeated venous sampling and for both administration of parenteral solutions and injections into the right colon of the rat for periods to 1 mo.

scholarly journals Evaluation of New Arterial Line System Kits with Blood-Sampling Device.

1999 ◽  
Vol 19 (2) ◽  
pp. 152-156
Author(s):  
Tomomichi KOGA ◽  
Michiyoshi SANUKI ◽  
Hiroyuki KINOSHITA ◽  
Kouji MIYASYOU ◽  
Shigeaki KURITA
Keyword(s):  
Blood Sampling ◽  
Arterial Line ◽  
Sampling Device ◽  
Line System

Novel Trisulfonated Poly(phthalazinone ether phosphine oxide)s with High Dimensional Stability for Proton Exchange Membrane

2020 ◽  
Vol 34 (4) ◽  
pp. 4999-5005 ◽  
Author(s):  
Shanshan Zhang ◽  
Huiping Liu ◽  
Yunlong Tan ◽  
Chen Lu ◽  
Songli Mao ◽  
...  
Keyword(s):  
Phosphine Oxide ◽  
Dimensional Stability ◽  
Proton Exchange Membrane ◽  
Proton Exchange ◽  
High Dimensional ◽  
Exchange Membrane

scholarly journals Research on the Properties of High-strength Gypsum Based Tile Adhesive in Interior Decoration

2020 ◽  
Vol 165 ◽  
pp. 05015
Author(s):  
Ji Xiu Zhang ◽  
Ye Zhang ◽  
Ji Kang Liu ◽  
Yuan Chao Miao ◽  
Sai Hong Duan
Keyword(s):  
Bond Strength ◽  
Dimensional Stability ◽  
High Strength ◽  
High Dimensional ◽  
Strength Development ◽  
Interior Decoration ◽  
High Bond ◽  
High Bond Strength ◽  
Early Strength ◽  
Interface Treatment

In this paper, a new early strength tile adhesive is prepared by using α- high strength gypsum and its properties are discussed. The research methods refer to relevant Chinese standards. The results show that the tensile bond strength of the adhesive can reach 0.6 MPa in one day and 1.5 MPa in 7 days, which is close to 80% of 28-day strength. It is indicating that the adhesive has high bond strength, rapid strength development, and high dimensional stability. It effectively solves the problems that the traditional cement-based tile adhesive is prone to hollowing, falling off, and cracking. Additionally, no interface treatment is required during the using process of this gypsum-based adhesive.

Characteristics of a new fully programmable blood sampling device for monitoring blood radioactivity during PET

2000 ◽  
Vol 28 (1) ◽  
pp. 81-89 ◽  
Author(s):  
Ronald Boellaard ◽  
Arthur van Lingen ◽  
Suzette C.M. van Balen ◽  
Bas G. Hoving ◽  
Adriaan A. Lammertsma
Keyword(s):  
Blood Sampling ◽  
Sampling Device ◽  
Blood Radioactivity

Preparation and Dimensional Stability of Organo-Montmorillonite (O-MMT) Treated Unsaturated Polyester Hybrid Composites Filled with Keratin Fiber

2014 ◽  
Vol 980 ◽  
pp. 28-32
Author(s):  
Kiew Kwong Siong ◽  
Soon Kok Heng ◽  
Sinin Hamdan ◽  
Moaz Mohsin ◽  
Akshay Kakar ◽  
...  
Keyword(s):  
Water Absorption ◽  
Dimensional Stability ◽  
Hybrid Composites ◽  
Unsaturated Polyester ◽  
Fiber Content ◽  
High Dimensional ◽  
Thickness Swelling ◽  
Stability Properties ◽  
Chicken Feathers ◽  
Keratin Fiber

O-MMT treated unsaturated polyester based hybrid composites were prepared using keratin fiber obtained from chicken feathers. Fibers of similar dimension were selected to fabricate composites through hand lay-up method. The preparation and dimensional stability properties of keratin fiber as reinforcements in composites is outlined in this paper. Varying O-MMT contents in nancomposites is performed to investigate the effects on the dimensional stability (water absorption and thickness swelling) of the composites. Results indicated that increasing fiber content deteriorates dimensional stability of the composites and composites. However, improvements in dimensional stability of the keratin fibercomposites were observed with O-MMT. O-MMT treatment reduces the water absorption and thickness swelling, especially at 5wt% of O-MMT concentrationat all range of fiber content. At 5wt% concentration of O-MMt, 10wt% keratin fiber content marks the lowest water absorption and thickness swelling with rate of 0.65% and 1.93%, respectively. Adopting 10wt% of keratin fiber at 5wt% of O-MMT can be utilized for application requiring high dimensional stability.

Electronic Mosquito: designing a semi-invasive Microsystem for blood sampling, analysis and drug delivery applications

2005 ◽  
Vol 12 (1-2) ◽  
pp. 44-51 ◽  
Author(s):  
Giorgio E. Gattiker ◽  
Karan V. I. S. Kaler ◽  
Martin P. Mintchev
Keyword(s):  
Drug Delivery ◽  
Blood Sampling ◽  
Drug Delivery Applications

scholarly journals Changes in Plasma Tryptophan and Melatonin Content in Penned Sheep

1978 ◽  
Vol 31 (1) ◽  
pp. 49
Author(s):  
DJ Kennaway ◽  
KJ Porter ◽  
RF Seamark
Keyword(s):  
Circadian Rhythms ◽  
Plasma Levels ◽  
Blood Sampling ◽  
Night Time ◽  
Sampling Device ◽  
Blood Constituents ◽  
Circadian Changes ◽  
Plasma Tryptophan ◽  
Tryptophan Content ◽  
The Relationship

The present study was undertaken to examine the relationship between the plasma levels of melatonin and its precursor tryptophan. No circadian changes in plasma total tryptophan content were evident which could be related to the marked night-time rise in plasma melatonin. An automated programmable blood sampling device suited to studies of circadian rhythms in blood constituents is described.

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