A Multi-agent Feature Selection and Hybrid Classification Model for Parkinson's Disease Diagnosis

2021 ◽  
Vol 17 (2s) ◽  
pp. 1-22
Author(s):  
Mazin Abed Mohammed ◽  
Mohamed Elhoseny ◽  
Karrar Hameed Abdulkareem ◽  
Salama A. Mostafa ◽  
Mashael S. Maashi
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Feature Selection ◽  
Prediction Models ◽  
Disease Diagnosis ◽  
Classification Model ◽  
Test Results ◽  
Multi Agent ◽  
The Voice

Parkinson's disease (PD) diagnostics includes numerous analyses related to the neurological, physical, and psychical status of the patient. Medical teams analyze multiple symptoms and patient history considering verified genetic influences. The proposed method investigates the voice symptoms of this disease. The voice files are processed, and the feature extraction is conducted. Several machine learning techniques are used to recognize Parkinson's and healthy patients. This study focuses on examining PD diagnosis through voice data features. A new multi-agent feature filter (MAFT) algorithm is proposed to select the best features from the voice dataset. The MAFT algorithm is designed to select a set of features to improve the overall performance of prediction models and prevent over-fitting possibly due to extreme reduction to the features. Moreover, this algorithm aims to reduce the complexity of the prediction, accelerate the training phase, and build a robust training model. Ten different machine learning methods are then integrated with the MAFT algorithm to form a powerful voice-based PD diagnosis model. Recorded test results of the PD prediction model using the actual and filtered features yielded 86.38% and 86.67% accuracies on average, respectively. With the aid of the MAFT feature selection, the test results are improved by 3.2% considering the hybrid model (HM) and 3.1% considering the Naïve Bayesian and random forest. Subsequently, an HM, which comprises a binary convolutional neural network and three feature selection algorithms (namely, genetic algorithm, Adam optimizer, and mini-batch gradient descent), is proposed to improve the classification accuracy of the PD. The results reveal that PD achieves an overall accuracy of 93.7%. The HM is integrated with the MAFT, and the combination realizes an overall accuracy of 96.9%. These results demonstrate that the combination of the MAFT algorithm and the HM model significantly enhances the PD diagnosis outcomes.

scholarly journals Cloud-Based Parkinson’s Disease Diagnosis Using Machine Learning

2021 ◽  
Vol 8 (6) ◽  
pp. 915-922
Author(s):  
Ahmed R. Nasser ◽  
Ali M. Mahmood
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Early Treatment ◽  
Intelligent System ◽  
Feature Selection Method ◽  
Disease Diagnosis ◽  
Classification Model ◽  
Accuracy Measurement ◽  
Diagnosis Model

Parkinson’s disease (PD) harms the human brain's nervous system and can affect the patient's life. However, the diagnosis of PD diagnosis in the first stages can lead to early treatment and save costs. In this paper, a cloud-based machine learning diagnosing intelligent system is proposed for the PD with respect to patient voice. The proposed system is composed of two stages. In the first stage, two machine learning approaches, Random-Forest (RF) and Long-Short-Term-Memory (LSTM) are applied to generate a model that can be used for early treatment of PD. In this stage, a feature selection method is used to choose the minimum subset of the best features, which can be utilized later to generate the classification model. In the second stage, the best diagnosis model is deployed in cloud computing. In this stage, an Android application is also designed to provide the interface to the diagnosis model. The performance evaluation of the diagnosis model is conducted based on the F-score accuracy measurement. The result shows that the LTSM model has superior accuracy with 95% of the F-score compared with the RF model. Therefore, the LSTM model is selected for implementing a cloud-based PD diagnosing application using Python and Java.

scholarly journals Classification of Parkinson’s disease with freezing of gait based on 360° turning analysis using 36 kinematic features

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Hwayoung Park ◽  
Sungtae Shin ◽  
Changhong Youm ◽  
Sang-Myung Cheon ◽  
Myeounggon Lee ◽  
...  
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Feature Selection ◽  
Stepwise Regression ◽  
Freezing Of Gait ◽  
Learning Model ◽  
Machine Learning Model ◽  
Body Kinematic ◽  
Full Body

Abstract Background Freezing of gait (FOG) is a sensitive problem, which is caused by motor control deficits and requires greater attention during postural transitions such as turning in people with Parkinson’s disease (PD). However, the turning characteristics have not yet been extensively investigated to distinguish between people with PD with and without FOG (freezers and non-freezers) based on full-body kinematic analysis during the turning task. The objectives of this study were to identify the machine learning model that best classifies people with PD and freezers and reveal the associations between clinical characteristics and turning features based on feature selection through stepwise regression. Methods The study recruited 77 people with PD (31 freezers and 46 non-freezers) and 34 age-matched older adults. The 360° turning task was performed at the preferred speed for the inner step of the more affected limb. All experiments on the people with PD were performed in the “Off” state of medication. The full-body kinematic features during the turning task were extracted using the three-dimensional motion capture system. These features were selected via stepwise regression. Results In feature selection through stepwise regression, five and six features were identified to distinguish between people with PD and controls and between freezers and non-freezers (PD and FOG classification problem), respectively. The machine learning model accuracies revealed that the random forest (RF) model had 98.1% accuracy when using all turning features and 98.0% accuracy when using the five features selected for PD classification. In addition, RF and logistic regression showed accuracies of 79.4% when using all turning features and 72.9% when using the six selected features for FOG classification. Conclusion We suggest that our study leads to understanding of the turning characteristics of people with PD and freezers during the 360° turning task for the inner step of the more affected limb and may help improve the objective classification and clinical assessment by disease progression using turning features.

scholarly journals Metaheuristics with Deep Learning-Enabled Parkinson’s Disease Diagnosis and Classification Model

2022 ◽  
Vol 2022 ◽  
pp. 1-14
Author(s):  
Adel A. Bahaddad ◽  
Mahmoud Ragab ◽  
Ehab Bahaudien Ashary ◽  
Eied M. Khalil
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Learning ◽  
Fitness Function ◽  
Disease Diagnosis ◽  
Classification Performance ◽  
Classification Model ◽  
Optimal Subset ◽  
Diagnosis And Classification ◽  
Optimum Solution

Parkinson's disease (PD) affects the movement of people, including the differences in writing skill, speech, tremor, and stiffness in muscles. It is significant to detect the PD at the initial stages so that the person can live a peaceful life for a longer time period. The serious levels of PD are highly risky as the patients get progressive stiffness, which results in the inability of standing or walking. Earlier studies have focused on the detection of PD effectively using voice and speech exams and writing exams. In this aspect, this study presents an improved sailfish optimization algorithm with deep learning (ISFO-DL) model for PD diagnosis and classification. The presented ISFO-DL technique uses the ISFO algorithm and DL model to determine PD and thereby enhances the survival rate of the person. The presented ISFO is a metaheuristic algorithm, which is inspired by a group of hunting sailfish to determine the optimum solution to the problem. Primarily, the ISFO algorithm is applied to derive an optimal subset of features with a fitness function of maximum classification accuracy. At the same time, the rat swarm optimizer (RSO) with the bidirectional gated recurrent unit (BiGRU) is employed as a classifier to determine the existence of PD. The performance validation of the IFSO-DL model takes place using a benchmark Parkinson’s dataset, and the results are inspected under several dimensions. The experimental results highlighted the enhanced classification performance of the ISFO-DL technique, and therefore, the proposed model can be employed for the earlier identification of PD.

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