Generative design of microfluidic channel geometry using evolutionary approach

Author(s):  
Nikolay O. Nikitin ◽  
Alexander Hvatov ◽  
Iana S. Polonskaia ◽  
Anna V. Kalyuzhnaya ◽  
Georgii V. Grigorev ◽  
...  
2012 ◽  
Vol 15 (1) ◽  
pp. 183-193 ◽  
Author(s):  
Phillip A. Coghill ◽  
Erin K. Kesselhuth ◽  
Eddie A. Shimp ◽  
Damir B. Khismatullin ◽  
David W. Schmidtke

2018 ◽  
Vol 47 (3) ◽  
pp. 350-353 ◽  
Author(s):  
Hirotoshi Yasaki ◽  
Takao Yasui ◽  
Takeshi Yanagida ◽  
Noritada Kaji ◽  
Masaki Kanai ◽  
...  

2019 ◽  
Vol 42 ◽  
Author(s):  
Marco Del Giudice

Abstract The argument against innatism at the heart of Cognitive Gadgets is provocative but premature, and is vitiated by dichotomous thinking, interpretive double standards, and evidence cherry-picking. I illustrate my criticism by addressing the heritability of imitation and mindreading, the relevance of twin studies, and the meaning of cross-cultural differences in theory of mind development. Reaching an integrative understanding of genetic inheritance, plasticity, and learning is a formidable task that demands a more nuanced evolutionary approach.


2010 ◽  
Vol 65 (1) ◽  
pp. 65-83 ◽  
Author(s):  
Bernadette Péley

A tanulmány amellett érvel, hogy az adaptív mechanizmusoknak és diszfunkcióiknak a finom elemzése jelentősen hozzájárul a fejlődés és a betegségek jobb megértéséhez, és a betegségek osztályozásának és a terápiáknak új útját nyithatja meg. Az evolúciós megközelítés a pszichoterápiába nem új elméletet vagy terápiás megközelítést kíván bevezetni, hanem az emberi természet törvényszerűségei mentén új megértési stratégiákat javasol. A patológiás szerveződést alapvetően az adaptivitás dimenziójában gondolja el. Ez kikényszeríti a fejlődési történet és a multikauzalitás szem előtt tartását. Hosszú távon ez a tüneti kategorizáción alapuló diagnosztika újragondolását is jelenti.


2020 ◽  
Vol 4 (3) ◽  
pp. 150-155 ◽  
Author(s):  
Md. Mehadi Hasan Sohag ◽  
Olivier Nicoud ◽  
Racha Amine ◽  
Abir Khalil-Mgharbel ◽  
Jean-Pierre Alcaraz ◽  
...  

AbstractThe goal of this study was to determine whether the Tethapod system, which was designed to determine the impedance properties of lipid bilayers, could be used for cell culture in order to utilise micro-impedance spectroscopy to examine further biological applications. To that purpose we have used normal epithelial cells from kidney (RPTEC) and a kidney cancer cell model (786-O). We demonstrate that the Tethapod system is compatible with the culture of 10,000 cells seeded to grow on a small area gold measurement electrode for several days without affecting the cell viability. Furthermore, the range of frequencies for EIS measurements were tuned to examine easily the characteristics of the cell monolayer. We demonstrate significant differences in the paracellular resistance pathway between normal and cancer kidney epithelial cells. Thus, we conclude that this device has advantages for the study of cultured cells that include (i) the configuration of measurement and reference electrodes across a microfluidic channel, and (ii) the small surface area of 6 parallel measurement electrodes (2.1 mm2) integrated in a microfluidic system. These characteristics might improve micro-impedance spectroscopy measurement techniques to provide a simple tool for further studies in the field of the patho-physiology of biological barriers.


2012 ◽  
Vol 1 (2) ◽  
pp. 36-49
Author(s):  
A. Kishore Kumar ◽  
D. Somasundareswari ◽  
V. Duraisamy ◽  
T. Shunbaga Pradeepa

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