Longitudinal distribution of canine respiratory heat and water exchanges

1989 ◽  
Vol 66 (6) ◽  
pp. 2788-2798 ◽  
Author(s):  
D. W. Ray ◽  
E. P. Ingenito ◽  
M. Strek ◽  
P. T. Schumacker ◽  
J. Solway
Keyword(s):  
Heat Loss ◽  
Wall Temperature ◽  
Minute Ventilation ◽  
Local Heat ◽  
Longitudinal Distribution ◽  
Evaporative Heat Loss ◽  
Airway Wall ◽  
Gas Temperature ◽  
Dry Air ◽  
Respiratory Heat Loss

We assessed the longitudinal distribution of intra-airway heat and water exchanges and their effects on airway wall temperature by directly measuring respiratory fluctuations in airstream temperature and humidity, as well as airway wall temperature, at multiple sites along the airways of endotracheally intubated dogs. By comparing these axial thermal and water profiles, we have demonstrated that increasing minute ventilation of cold or warm dry air leads to 1) further penetration of unconditioned air into the lung, 2) a shift of the principal site of total respiratory heat loss from the trachea to the bronchi, and 3) alteration of the relative contributions of conductive and evaporative heat losses to local total (conductive plus evaporative) heat loss. These changes were not accurately reflected in global measurements of respiratory heat and water exchange made at the free end of the endotracheal tube. Raising the temperature of inspired dry air from frigid to near body temperature principally altered the mechanism of airway cooling but did not influence airway mucosal temperature substantially. When local heat loss was increased from both trachea and bronchi (by increasing minute ventilation), only the tracheal mucosal temperature fell appreciably (up to 4.0 degrees C), even though the rise in heat loss from the bronchi about doubled that in the trachea. Thus it appears that the bronchi are better able to resist changes in airway wall temperature than is the trachea. These data indicate that the sites, magnitudes, and mechanisms of respiratory heat loss vary appreciably with breathing pattern and inspired gas temperature and that these changes cannot be predicted from measurements made at the mouth. In addition, they demonstrate that local heat (and presumably, water) sources that replenish mucosal heat and water lost to the airstream are important in determining the degree of local airway cooling (and presumably, drying).

Respiratory water and heat loss of the black duck during flight at different ambient temperatures

1971 ◽  
Vol 49 (5) ◽  
pp. 767-774 ◽  
Author(s):  
M. Berger ◽  
J. S. Hart ◽  
O. Z. Roy
Keyword(s):  
Heat Loss ◽  
Water Loss ◽  
Pulmonary Ventilation ◽  
Evaporative Heat Loss ◽  
Total Heat Loss ◽  
Ambient Temperatures ◽  
Black Duck ◽  
Respiratory Heat Loss ◽  
Metabolic Water ◽  
Expired Air

Pulmonary ventilation and temperature of expired air and of the respiratory passages has been measured by telemetry during flight in the black duck (Anas rubripes) and the respiratory water and heat loss has been calculated.During flight, temperature of expired air was higher than at rest and decreased with decreasing ambient temperatures. Accordingly, respiratory water loss as well as evaporative heat loss decreased at low ambient temperatures, whereas heat loss by warming of the inspired air increased. The data indicated respiratory water loss exceeded metabolic water production except at very low ambient temperatures. In the range between −16 °C to +19 °C, the total respiratory heat loss was fairly constant and amounted to 19% of the heat production. Evidence for the independence of total heat loss and production from changes in ambient temperature during flight is discussed.

Eicosanoids modulate hyperpnea-induced bronchoconstriction in canine peripheral airways

1996 ◽  
Vol 81 (3) ◽  
pp. 1255-1263 ◽  
Author(s):  
C. Omori ◽  
P. Tagari ◽  
A. N. Freed
Keyword(s):  
Bronchoalveolar Lavage ◽  
Wall Temperature ◽  
Airway Resistance ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid ◽  
Airway Wall ◽  
Airway Reactivity ◽  
Dry Air ◽  
Peripheral Airways ◽  
Peripheral Airway

We examined the role of leukotrienes (LTs) in the development of dry air-induced bronchoconstriction (AIB) in canine peripheral airways. Airway reactivity to exogenous LTs was first tested by using an LTD4 aerosol challenge: peripheral airway resistance increased approximately 130 +/- 51% (n = 4) above baseline when compared with its vehicle control. AIB was then assessed by measuring peripheral airway resistance after, and airway wall temperature during, a dry air challenge (DAC). Treatment with a peptidoleukotriene biosynthesis inhibitor (MK-0591) attenuated AIB by approximately 65% without altering airway wall temperature. The fact that MK-0591 did not alter airway reactivity to aerosolized acetylcholine and completely inhibited Ca2+ ionophore-induced LTB4 generation in canine whole blood attests to the specificity of the drug. Treatment with MK-0591 did not affect the increased number of epithelial cells recovered in bronchoalveolar lavage fluid 5 min after DAC. Concentrations of LTs and other eicosanoids in bronchoalveolar lavage fluid from vehicle-treated DAC airways were increased above baseline values; only LTs were reduced by MK-0591. Before MK-0591, AIB was significantly correlated with the dry air-induced generation of LTC4, LTD4, and LTE4. After treatment with MK-0591, AIB was correlated with thromboxane B2, prostaglandin (PG) F2 alpha, and PGE2. We conclude that hyperpnea with dry air stimulates local production and release of LTs in canine bronchi and, alone with the generation of bronchoconstricting and bronchodilating PGs, plays a central role in the modulation of AIB.

RESPIRATORY CONTRIBUTION TO THE THERMAL BALANCE OF THE NEWBORN INFANT UNDER VARIOUS AMBIENT CONDITIONS

PEDIATRICS ◽  
1973 ◽  
Vol 51 (4) ◽  
pp. 641-650
Author(s):  
E. Sulyok ◽  
E. Jéquier ◽  
L. S. Prod'hom
Keyword(s):  
Ambient Temperature ◽  
Heat Loss ◽  
Newborn Infant ◽  
Thermal Environment ◽  
Newborn Infants ◽  
Thermal Balance ◽  
Evaporative Heat Loss ◽  
Ambient Conditions ◽  
Direct Calorimetry ◽  
Respiratory Heat Loss

The influence of environmental humidity and temperature on the thermal balance of 45 full-term newborn infants was studied by direct calorimetry within 24 hours after birth. The respiratory heat loss measured at 32C and 20% relative humidity (RH) represented 9.5% of the total heat production, and it decreased to 2.9% when RH was 80%. In neutral thermal environment (32C, 50% RH), the mean respiratory heat loss was lower than that measured during a warm exposure (36C, 50% RH), in spite of a higher absolute humidity in the latter condition. This suggests that respiration might have a thermoregulatory function during heat exposure in the newborn. Evaporative heat loss from the skin was more elevated than that from the respiratory tract, but it was less sensitive to change in ambient humidity. Convective and radiative heat losses from the skin were inversely related to ambient temperature; similarly, the metabolic rate decreased with increasing ambient temperature up to 36C. This work provides further data on the varying energy exchange between the newborn infant and his environment; it should lead to a more rational planning of infant care and caloric requirements and demonstrates the important effects of different environmental conditions on the newborn infant.

Influence of air temperature on ventilation rates and thermoregulation of a flying bat

1991 ◽  
Vol 260 (5) ◽  
pp. R960-R968 ◽  
Author(s):  
S. P. Thomas ◽  
D. B. Follette ◽  
A. T. Farabaugh
Keyword(s):  
Heat Loss ◽  
Minute Ventilation ◽  
Ventilation Rate ◽  
Evaporative Heat Loss ◽  
Breathing Frequency ◽  
Significant Extent ◽  
Metabolic Heat ◽  
Air Temperatures ◽  
Phyllostomus Hastatus ◽  
Ventilation Rates

To assess the involvement of the ventilatory system in thermoregulation during flight, breathing frequencies and tidal volumes were measured from three Phyllostomus hastatus undertaking steady wind tunnel flights at a constant speed over a range of air temperatures (Ta) from 17.7 to 31.1 degrees C. Mean breathing frequency was independent of Ta, and tidal volume increased only modestly with increasing Ta. Consequently, minute ventilation rate increased insignificantly over the range of Ta values investigated. Mean rectal temperature showed a direct linear relation to Ta and increased significantly from 39.1 to 41.9 degrees C over the range of Ta values investigated. The highest rectal temperatures measured from flying P. hastatus are approximately 3 degrees C less than those of flying birds. In contrast to flying birds, flying P. hastatus does not modulate its rate of respiratory evaporative heat loss to any significant extent in response to environmental heat stress and only loses an estimated 14% of its metabolic heat load by this route. Cutaneous heat loss channels must therefore be very important to these animals. Some reasons for the observed differences in the thermoregulatory responses of flying bats and birds are discussed as well as the relative advantages and limitations of each group's solutions to their thermoregulatory challenges.

Airway effects of respiratory heat loss in normal subjects

1980 ◽  
Vol 49 (5) ◽  
pp. 875-880 ◽  
Author(s):  
C. F. O'Cain ◽  
N. B. Dowling ◽  
A. S. Slutsky ◽  
M. J. Hensley ◽  
K. P. Strohl ◽  
...  
Keyword(s):  
Heat Loss ◽  
Minute Ventilation ◽  
Normal Subjects ◽  
Flow Rates ◽  
Exhausting Exercise ◽  
Respiratory Heat Loss ◽  
Heavy Work

The increased minute ventilation (VE) associated with exercise produces similar degrees of airway cooling in normal and asthmatic subjects, but only those with asthma develop postexertional bronchoconstriction in response to this stimulus. We have found that when normal subjects breathing subfreezing air perform isocapnic hyperventilation to levels exceeding those associated with even exhausting exercise, 1-s forced expiratory volumes and maximum midexpiratory flow rates fall significantly. When tests more sensitive in detecting bronchoconstriction are employed, changes are seen at lower levels of hyperventilation that simulate the VE associated with moderately heavy work loads. We conclude that normal subjects respond to airway cooling, but are much less sensitive than those with asthma.

Thermal responses in humans exposed to cold hyperbaric helium-oxygen

1980 ◽  
Vol 49 (6) ◽  
pp. 1099-1106 ◽  
Author(s):  
C. A. Piantadosi ◽  
E. D. Thalmann
Keyword(s):  
Heat Loss ◽  
Heat Production ◽  
Cold Water ◽  
Minute Ventilation ◽  
Water Immersion ◽  
Heat Losses ◽  
Metabolic Heat Production ◽  
Metabolic Heat ◽  
Respiratory Heat Loss ◽  
Wide Range

The relationship of metabolic heat production to skin and core temperatures, cutaneous heat flow, and respiratory heat loss was measured in 10 male subjects cooled in hyperbaric helium at 20.7 ATA and 15 or 20 degrees C for 60-120 min. Under these conditions, metabolic heat production tended to compensate for the sum of convective and radiant heat losses from the skin but did not increase sufficiently to compensate for additional respiratory heat losses. There was a positive correlation between respiratory heat loss and fall in rectal temperature. Individual variability in ventilatory response to cold hyperbaric helium exposure as shown by a wide range of minute ventilation-to-oxygen consumption ratios (VE/VO2) was similar to that reported during cold water immersion. Subjects with high VE/VO2 had low mean physiological shell insulation values and lost more heat through the skin as well as through the respiratory tract than subjects with low VE/VO2.

Interval microclimate cooling with the Dry Air Comfort (DAC) method: An effective strategy to sustain evaporative heat loss

2017 ◽  
Vol 20 ◽  
pp. S45
Author(s):  
Karl Jochen Glitz ◽  
Uwe Seibel ◽  
Stefan Freitag ◽  
Ulrich Rohde ◽  
Willi Gorges ◽  
...  
Keyword(s):  
Heat Loss ◽  
Evaporative Heat Loss ◽  
Effective Strategy ◽  
Dry Air ◽  
Microclimate Cooling

Changes in serotonin contents in brain affect metabolic heat production of rabbits in cold

1978 ◽  
Vol 235 (1) ◽  
pp. R41-R47
Author(s):  
M. T. Lin ◽  
I. H. Pang ◽  
S. I. Chern ◽  
W. Y. Chia
Keyword(s):  
Blood Flow ◽  
Amino Acid ◽  
Heat Loss ◽  
Acid Decarboxylase ◽  
Evaporative Heat Loss ◽  
Decarboxylase Inhibitor ◽  
Ambient Temperatures ◽  
Amino Acid Decarboxylase ◽  
Metabolic Heat ◽  
Normal Limits

Elevating serotonin (5-HT) contents in brain with 5-hydroxytryptophan (5-HTP) reduced rectal temperature (Tre) in rabbits after peripheral decarboxylase inhibition with the aromatic-L-amino-acid decarboxylase inhibitor R04-4602 at two ambient temperatures (Ta), 2 and 22 degrees C. The hypothermia was brought about by both an increase in respiratory evaporative heat loss (Eres) and a decrease in metabolic rate (MR) in the cold. At a Ta of 22 degrees C, the hypothermia was achieved solely due to an increase in heat loss. Depleting brain contents of 5-HT with intraventricular, 5,7-dihydroxytryptamine (5,7-DHT) produced an increased Eres and ear blood flow even at Ta of 2 degrees C. Also, MR increased at all but the Ta of 32 degrees C. However, depleting the central and peripheral contents of 5-HT with p-chlorophenylalanine (pCPA) produced lower MR accompanied by lower Eres in the cold compared to the untreated control. Both groups of pCPA-treated and 5,7-DHT-treated animals maintained their Tre within normal limits. The data suggest that changes in 5-HT content in brain affects the MR of rabbits in the cold. Elevating brain content of 5-HT tends to depress the MR response to cold, while depleting brain content of 5-HT tends to enhance the MR response to cold.

Evaporative Heat Loss Mechanisms of the Newborn Calf, Bos Taurus

1968 ◽  
Vol 124 (2) ◽  
pp. 83-88 ◽  
Author(s):  
J.R.S. Hales ◽  
J.D. Findlay ◽  
D. Robertshaw
Keyword(s):  
Heat Loss ◽  
Bos Taurus ◽  
Evaporative Heat Loss ◽  
Loss Mechanisms

Effects of environmental temperature and humidity on evaporative heat loss through firefighter suit materials made with semi-permeable and microporous moisture barriers

2021 ◽  
pp. 004051752110265
Author(s):  
Huipu Gao ◽  
Anthoney Shawn Deaton ◽  
Xiaomeng Fang ◽  
Kyle Watson ◽  
Emiel A DenHartog ◽  
...  
Keyword(s):  
Heat Loss ◽  
Environmental Temperature ◽  
Moisture Absorption ◽  
Evaporative Heat Loss ◽  
Total Heat Loss ◽  
Evaporative Resistance ◽  
Environmental Testing ◽  
Permeable Barrier ◽  
Moisture Condensation ◽  
Moisture Barriers

The goal of this research was to understand how firefighter protective suits perform in different operational environments. This study used a sweating guarded hotplate to examine the effect of environmental temperature (20–45°C) and relative humidity (25–85% RH) on evaporative heat loss through firefighter turnout materials. Four firefighter turnout composites containing three different bi-component (semi-permeable) and one microporous moisture barriers were selected. The results showed that the evaporative resistance of microporous moisture barrier systems was independent of environmental testing conditions. However, absorbed moisture strongly affected evaporative heat loss through semi-permeable moisture barriers coated with a layer of nonporous hydrophilic polymer. Moisture absorption in mild environment (20–25°C) tests, or when testing at high humidity (>85% RH), significantly increased water vapor transmission in semi-permeable turnout systems. It was also found that environmental conditions used in the total heat loss (THL) test (25°C and 65% RH) produced moisture condensation in bi-component barrier systems, making them appear more breathable than could be expected when worn in hotter environments. Regression models successfully qualified the relationships between moisture uptake levels in semi-permeable barrier systems and evaporative resistance and THL. These findings reveal the limitations in relying on THL, the heat strain index currently called for by the NFPA 1971 Standard for Structural Firefighter personal protective equipment, and supports the need to measure turnout evaporative resistance at 35°C (Ret), in addition to THL at 25°C.

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