Evidence of LPL gene-exercise interaction for body fat and LPL activity: the HERITAGE Family Study

2001 ◽  
Vol 91 (3) ◽  
pp. 1334-1340 ◽  
Author(s):  
Christophe Garenc ◽  
Louis Pérusse ◽  
Jean Bergeron ◽  
Jacques Gagnon ◽  
Yvon C. Chagnon ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Black Women ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Visceral Fat ◽  
White Women ◽  
Percent Body Fat ◽  
Heparin Plasma ◽  
Abdominal Visceral Fat

Evidence of a gene-exercise interaction for traits related to body composition is limited. Here, the association between the lipoprotein lipase (LPL) S447X polymorphism and changes in body mass index, fat mass, percent body fat, abdominal visceral fat measured by computed tomography, and post-heparin plasma LPL activity in response to 20 wk of endurance training was investigated in 741 adult white and black subjects. Changes were compared between carriers and noncarriers of the X447 allele after adjustment for the effects of age and pretraining values. No evidence of association was observed in men. However, white women carrying the X447 allele exhibited greater reductions of body mass index ( P= 0.01), fat mass ( P = 0.01), and percent body fat ( P = 0.03); in black women, the carriers exhibited a greater reduction of abdominal visceral fat ( P = 0.05) and a greater increase in post-heparin LPL activity ( P = 0.02). These results suggest that the LPL S447X polymorphism influences the training-induced changes in body fat and post-heparin LPL activity in women but not in men.

Limitations of body mass index for counseling individuals with unilateral lower extremity amputation

2016 ◽  
Vol 41 (2) ◽  
pp. 186-193 ◽  
Author(s):  
Alexandra P Frost ◽  
Tracy Norman Giest ◽  
Allison A Ruta ◽  
Teresa K Snow ◽  
Mindy Millard-Stafford
Keyword(s):  
Body Mass Index ◽  
Lower Extremity ◽  
Health Risk ◽  
Body Mass ◽  
Body Fat ◽  
Lower Limb ◽  
Dual Energy ◽  
Limb Loss ◽  
Percent Body Fat ◽  
X Ray

Background: Body composition is important for health screening, but appropriate methods for unilateral lower extremity amputees have not been validated. Objectives: To compare body mass index adjusted using Amputee Coalition equations (body mass index–Amputee Coalition) to dual-energy X-ray absorptiometry in unilateral lower limb amputees. Study design: Cross-sectional, experimental. Methods: Thirty-eight men and women with lower limb amputations (transfemoral, transtibial, hip disarticulation, Symes) participated. Body mass index (mass/height2) was compared to body mass index corrected for limb loss (body mass index–Amputee Coalition). Accuracy of classification and extrapolation of percent body fat with body mass index was compared to dual-energy X-ray absorptiometry. Results: Body mass index–Amputee Coalition increased body mass index (by ~ 1.1 kg/m2) but underestimated and mis-classified 60% of obese and overestimated 100% of lean individuals according to dual-energy X-ray absorptiometry. Estimated mean percent body fat (95% confidence interval) from body mass index–Amputee Coalition (28.3% (24.9%, 31.7%)) was similar to dual-energy X-ray absorptiometry percent body fat (29.5% (25.2%, 33.7%)) but both were significantly higher ( p < 0.05) than percent body fat estimated from uncorrected body mass index (23.6% (20.4%, 26.8%)). However, total errors for body mass index and body mass index–Amputee Coalition converted to percent body fat were unacceptably large (standard error of the estimate = 6.8%, 6.2% body fat) and the discrepancy between both methods and dual-energy X-ray absorptiometry was inversely related ( r = −0.59 and r = −0.66, p < 0.05) to the individual’s level of body fatness. Conclusions: Body mass index (despite correction) underestimates health risk for obese patients and overestimates lean, muscular individuals with lower limb amputation. Clinical relevance Clinical recommendations for an ideal body mass based on body mass index–Amputee Coalition should not be relied upon in lower extremity amputees. This is of particular concern for obese lower extremity amputees whose health risk might be significantly underestimated based on body mass index despite a “correction” formula for limb loss.

Body mass index and percent body fat: a meta analysis among different ethnic groups

1998 ◽  
Vol 22 (12) ◽  
pp. 1164-1171 ◽  
Author(s):  
P Deurenberg ◽  
M Yap ◽  
WA van Staveren
Keyword(s):  
Body Mass Index ◽  
Ethnic Groups ◽  
Body Mass ◽  
Body Fat ◽  
Meta Analysis ◽  
Percent Body Fat

A comparison of body mass index and percent body fat as predictors of cardiovascular risk factors

2019 ◽  
Vol 13 (1) ◽  
pp. 570-575 ◽  
Author(s):  
Hosein Sheibani ◽  
Habibollah Esmaeili ◽  
Maryam Tayefi ◽  
Maryam Saberi-Karimian ◽  
Susan Darroudi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Body Mass ◽  
Body Fat ◽  
Percent Body Fat

Prevalence of obesity using the body mass index and equivalent age- and sex-specific thresholds for percentage body fat mass

2013 ◽  
Vol 7 ◽  
pp. e93
Author(s):  
Julie A. Pasco ◽  
Haslinda Gould ◽  
Kara L. Holloway ◽  
Amelia G. Dobbins ◽  
Mark A. Kotowicz ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
The Body ◽  
Body Fat Mass ◽  
Percentage Body Fat ◽  
Equivalent Age ◽  
Prevalence Of Obesity ◽  
Age And Sex

scholarly journals Body Morphometrics in NAFLD Population

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Harkeerat Dhami ◽  
Niharika Samala
Keyword(s):  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Percent Body Fat ◽  
Composition Analysis ◽  
Processed Meat ◽  
Body Fat Mass ◽  
High Sodium ◽  
Obstructive Sleep

Introduction: NAFLD is one of the common causes of liver disease in the US and is commonly associated with metabolic syndrome. Among obese, prevalence of NAFLD is 7090%. We wanted to determine body morphometrics in NAFLD. Methods: All individuals presenting to Indiana University Hospital with NAFLD were approached to participate in cross-sectional study. All participants were offered beverage, diet (REAP) questionnaires and body composition analysis using InBody 570, which utilizes bioelectrical impedance. Results: Of the 321 NAFLD individuals enrolled, 256 completed body morphometric analysis. Mean age of the cohort was 51.58 ± 13.54, 58% were female, 297 White and had a mean BMI of 35.92. 76% were obese, 48% had type 2 diabetes, 49.2% had hypertension, 38.6% had dyslipidemia, and 20.5% had obstructive sleep apnea. Despite having similar BMI, females had lower lean body mass (51.01 vs 70.51) and skeletal muscle mass (28.05 vs 39.70), higher body fat mass (46.71 vs 41.04) and percent body fat (46.59 vs. 35.7). Regular coffee consumers had lower BMI (35.3 vs 38, p=0.038), but lower body fat mass (39.9 vs 46.2, p=0.01), percent body fat (41.1 vs 44.4, p=0.05) and higher lean body mass % (58.8 vs 55.5, p=0.049). Processed meat consumption was associated with higher BMI (39 vs 35.3, P=0.01), percent body fat (45.5 vs 42, p=0.04), and lower lean body mass percentage (54.5 vs 58.2, P=0.04). Similar trends were seen with consumption of high sodium processed foods and watching television for ≥ 2 hours/day. Conclusion: Among individuals with NAFLD, we saw a higher female preponderance, who were found to have unfavorable body morphometrics despite similar BMI as males. Consumption of high sodium processed food and meat and excess screen time have unfavorable, while regular coffee drinkers have favorable body morphometrics, which offer modifiable measures for risk factors associated with NAFLD.

scholarly journals An investigation into the effect of body mass index on the agreement between whole-body fat mass determined by MRI and air-displacement plethysmography

2019 ◽  
Vol 92 (1103) ◽  
pp. 20190300
Author(s):  
Andrew D. Weedall ◽  
Adrian J. Wilson ◽  
Sarah C. Wayte
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Whole Body ◽  
Body Fat Mass ◽  
Fat Percentage ◽  
Air Displacement Plethysmography ◽  
Obese Subjects ◽  
Test Objects

Objective: To validate MRI fat measurement protocols using purpose built test objects and by comparison with air-displacement plethysmography (ADP) whole-body fat measurements in non-obese subjects. Methods: Test objects of known fat concentration were used to quantify the accuracy of the MRI measurements. 10 participants with a body mass index in the range 18–30 underwent whole-body MRI using two different Dixon-based sequences (LAVA Flex and IDEAL IQ) to obtain an estimate of their whole-body fat mass. The MRI determined fat mass was compared to the fat mass determined by ADP. Results: MRI test object measurements showed a high correlation to expected fat percentage (r > 0.98). The participant MRI and ADP results were highly correlated (r = 0.99) but on average (mean ± standard deviation) MRI determined a higher fat mass than ADP (3.8 ± 3.1 kg for LAVA Flex and 1.9 ± 3.2 kg for IDEAL IQ). There was no trend in the difference between MRI and ADP with total fat mass. Conclusion: The good agreement between MRI and ADP shows that Dixon-based MRI can be used effectively as a tool in physiological research for non-obese adults. Advances in knowledge: This work found that for ten non-obese subjects body mass index had no effect on the MRI determination of whole-body fat mass.

scholarly journals Lipoprotein Metabolism, Insulin Resistance, and Adipocytokine Levels in Japanese Female Adolescents With a Normal Body Mass Index and High Body Fat Mass

2009 ◽  
Vol 73 (3) ◽  
pp. 534-539 ◽  
Author(s):  
Noriaki Kishimoto ◽  
Koichi Okita ◽  
Shingo Takada ◽  
Ichiro Sakuma ◽  
Yasuaki Saijo ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Body Mass Index ◽  
Body Mass ◽  
Body Fat ◽  
Fat Mass ◽  
Lipoprotein Metabolism ◽  
Female Adolescents ◽  
Normal Body Mass Index ◽  
Body Fat Mass ◽  
Japanese Female
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