scholarly journals Effect ofSiraitia GrosvenoriiPolysaccharide on Glucose and Lipid of Diabetic Rabbits Induced by Feeding High Fat/High Sucrose Chow

2007 ◽  
Vol 2007 ◽  
pp. 1-4 ◽  
Author(s):  
Guo-Ping Lin ◽  
Tao Jiang ◽  
Xiao-Bo Hu ◽  
Xin-Hui Qiao ◽  
Qin-Hui Tuo

TheSiraitia grosvenoriipolysaccharide (SGP) from theSiraitia grosvenorii(Swingle) was isolated and purified. The therapeutic effects of SGP on diabetic rabbits induced by feeding high fat/high sucrose chow were studied. After administration of SGP for 4 weeks, the fasting blood glucose (FBG), plasma insulin levels (INS), plasma total cholesterol (TC), triglyceride (TG), and HDL-C were assayed. The results showed that administration of SGP can significantly decrease plasma total cholesterol, triglyceride, and glucose levels; and increase HDL-C levels after 4 weeks of treatment. The antihyperglycaemic effect of SGP at dose of 100 mg⋅kg−1bw was the most significant in three dosage groups. Furthermore, SGP could restore the blood lipid levels of diabetic rabbits (P<.05). These data indicate that SGP not only ameliorates the lipid disorder, but also lowers plasma glucose levels. So SGP have obvious glucose-lowering effect on hyperglycaemic rabbits induced by feeding high fat/high sucrose chow, its mechanism may be related to amelioration of lipid metabolism and restoring the blood lipid levels of hyperglycaemic rabbits.

1968 ◽  
Vol 21 (5) ◽  
pp. 1025 ◽  
Author(s):  
JC O'kelly

Breed differences in plasma lipid levels were previously reported for cattle grazing near Rockhampton, Qld. The present study investigated the blood lipids of British� and Zebu� type cattle subjected to the same dietary treatments. On high-quality diets only plasma non�esterified fatty acid concentrations were significantly affected (P < 0�01) by level of intake. Plasma total cholesterol, phospholipid, and triglyceride levels were depressed by a low-quality diet which elevated the free: total cholesterol ratio.


2005 ◽  
Vol 19 (4) ◽  
pp. 284-289 ◽  
Author(s):  
Ana Cristina Posch Machado ◽  
Maria Rozeli de Souza Quirino ◽  
Luiz Fernando Costa Nascimento

Many people in the world are affected by hyperlipidemia, which is a known risk factor for atherosclerotic disease. On the other hand, periodontitis, a prevalent oral disease, has been connected to several systemic health changes, including an altered lipid metabolism. Transient and recurrent bacteremias, which may be caused by periodontal infection, induce an intense local and systemic inflammatory response, leading to changes in the whole body. The aim of the present study was to verify the relationship between severe and moderate periodontal disease and blood lipid levels. Sixty individuals seen at the clinics of the University of Taubaté, São Paulo, over 20 years old, were divided into two groups, with and without periodontitis, and paired according to sex and age. Their levels of total cholesterol, tryglicerides and fractions were determined. Variables related to high cholesterol levels, including age, sex and body mass index, were evaluated. The values recommended by the Brazilian Society of Cardiology were considered to classify lipidemia. The results showed that mean levels of cholesterol (192.1 mg/dl ± 40.9) and triglycerides (153.5 mg/dl ± 105.6) in individuals with periodontitis were higher than, but not statistically different from, those of individuals without periodontitis (186.1 mg/dl ± 35.4 and 117.5 mg/dl ± 68, respectively). Therefore, this study has demonstrated that there is no significant relationship between periodontal disease, regardless of its intensity, and blood lipid levels in the studied population.


2020 ◽  
Vol 11 (2) ◽  
pp. 265-270
Author(s):  
Tejas Laxman Kakade ◽  
Sadhana Misar Wajpeyi

Dyslipidemia is considered as metabolic disorders related to lipoprotein metabolism, manifested as rise in plasma levels of total Cholesterol, Triglyceride (TGs), or both, or a decrease in high density lipoprotein level or all three together that contributes to the formation of atherosclerosis. It can be included under santarpanjanyavyadhi. Various conditions like Shonitabhishyandana, Rasagata SnehaVriddhi (raised plasma lipid levels), Rasaraktagata Snehavriddhi (raised plasma and blood lipid levels), Medovriddhi (elevation of generalized fat), Medoroga (obesity), Aam Medodhatu (abnormal form of adipose tissue) can be correlated with Dyslipidemia due to resemblance of their etiopathogenesis and clinical features. Total 30 patients of dyslipidemia fulfilling the diagnostic criteria were selected and treated with Yavavati 1.5 gm twice a day before meal with lukewarm water for 30 days. In this study it was observed that incidence of  Dyslipidemia was more in advanced ages,female gender, middle socioeconomic group individuals having vatapittajaprakruti, madhyamagni and madhyamaakruti. In present study, sedentary lifestyle, day sleep, association of other diseases like hypertension, DM, hypothyroidism and hemiplegia are the main causative factors for Dyslipidemia. Yavavati showed significant improvement in BMI, total cholesterol, S.Triglicerides, S.VLDL and HDL level. This improvement may be due to its ruksha, lekhana, kaphamedahar, agnivadhaka and apatarpana properties of Yavavati. Hence from this study it can be concluded that, Yavavati is effective and can be safely used in the management of Dyslipidemia.


2019 ◽  
Vol 69 (4) ◽  
pp. 1189
Author(s):  
Ugur Aydogdu ◽  
A. Coskun ◽  
R. Yildiz ◽  
H. Guzelbektes ◽  
I. Sen

In this study, it was aimed to determine of diagnostic importance blood lipid levels in neonatal calves with sepsis. The study was carried out on a total of 70 calves, 60 with sepsis and 10 healthy calves. The calves with sepsis were included in the study, according to clinical and hematological findings.  After routine clinical examinations of all the calves, blood samples were taken from the V. jugularis for hematological, lipid profile and biochemical analyzes. There were significantly (P < 0.05) decreased in body temperature, increased in respiration rate and capillary refill time in the calves with sepsis, compared to control group calves. The levels of blood urea nitrogen, creatinine concentrations of calves with sepsis were significantly higher (P < 0.05), however, levels of total cholesterol, HDL, LDL and albumin concentrations were significantly lower (P < 0.05) than control group. In addition, blood triglyceride and VLDL concentrations of calves with sepsis were higher than control group, however there was no statistical difference.In conclusion, serum total cholesterol, HDL and LDL in neonatal calves with sepsis could be used in evaluation of the sepsis.


2014 ◽  
Vol 884-885 ◽  
pp. 423-428
Author(s):  
Yan Hui Yang ◽  
Guo Qiang Zheng ◽  
Juan Tang ◽  
Yue Meng Wang ◽  
Chuan Wang Zhu ◽  
...  

The effect of Armillaria mellea on blood lipid levels and oxidative stress in mice fed on high-fat diet was investigated. Animals were allocated to the Armillaria mellea polysaccharides-treatment groups (I, II) and Armillaria mellea oligosaccharides-treatment groups (I, II). All mice were fed with high-fat diet for 40 days but control mice with basic diet. TC, TG, HDL-c, LDL-c were measured by enzymatic and colorimetric methods. The same, MDA,SOD, GSH-PX were measured. Results showed that administration of Armillaria mellea polysaccharides and oligosaccharides significantly increased antioxidant enzymes GSH-Px activities and decreased TC, TG, LDL-c, MDA level in mice (P < 0.05) compared with model group. In conclusion Armillaria mellea polysaccharides and oligosaccharides were able to protect mices antioxidative and improve abnormal blood lipid levels.


Author(s):  
A. Thelin ◽  
E.-L. Stiernstrom ◽  
S. Holmberg

Sign in / Sign up

Export Citation Format

Share Document