scholarly journals Maternal History and Uterine Artery Doppler in the Assessment of Risk for Development of Early- and Late-Onset Preeclampsia and Intrauterine Growth Restriction

2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
Elisa Llurba ◽  
Elena Carreras ◽  
Eduard Gratacós ◽  
Miquel Juan ◽  
Judith Astor ◽  
...  
Keyword(s):  
Risk Factors ◽  
Early Onset ◽  
Intrauterine Growth Restriction ◽  
Uterine Artery ◽  
Late Onset ◽  
Maternal Risk Factors ◽  
Maternal History ◽  
Uterine Artery Doppler ◽  
Maternal Risk ◽  
Intrauterine Growth

Objective. To examine the value of one-step uterine artery Doppler at 20 weeks of gestation in the prediction pre-eclampsia (PE) and/or intrauterine growth restriction (IUGR).Methods. A prospective multicentre study that included all women with singleton pregnancies at 19–22 weeks of gestation (w). The mean pulsatility index (mPI) of both uterine arteries was calculated. Receiver-operating characteristics curves (ROC) were drawn to compare uterine artery Doppler and maternal risk factors for the prediction of early-onset PE and/or IUGR (before 32 w) and late-onset PE and/or IUGR.Results. 6,586 women were included in the study. Complete outcome data was recorded for 6,035 of these women (91.6%). PE developed in 75 (1.2%) and IUGR in 69 (1.1%) cases. Uterine Doppler mPI was 0.99 and the 90th centile was 1.40. For 10% false-positive rate, uterine Doppler mPI identified 70.6% of pregnancies that subsequently developed early-onset PE and 73.3% of pregnancies that developed early-onset IUGR. The test had a lower detection rate for the late-onset forms of the disease (23.5% for PE and 30% for IUGR). Maternal history has a low sensitivity in the detection of early-onset cases, although it is better at detecting late-onset PE.Conclusion. Uterine artery Doppler and maternal risk factors seem to select two different populations - early and late-onset PE which might suggest a different pathogenesis.

NEONATAL SEPSIS AND RISK FACTORS, STUDY IN IN AVBRH TERTIARY CARE HOSPITAL

2019 ◽  
Vol 3 (3) ◽  
Author(s):  
Pramod P. Singhavi
Keyword(s):  
Risk Factors ◽  
Neonatal Sepsis ◽  
Early Onset ◽  
Late Onset ◽  
Signs And Symptoms ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Late Onset Sepsis ◽  
Early Onset Sepsis ◽  
Meconium Stained Amniotic Fluid

Introduction: Neonatal sepsis can be defined as a clinical condition which is characterized by signs and symptoms of infection in an infant 28 days of life or younger. This is manifested by systemic signs of infection and/ or isolation of a bacterial or other pathogen from the bloodstream. Sepsis is still one of the major causes of morbidity and mortality globally in neonates, despite of recent advances in healthcare units. The incidence of neonatal sepsis by bacteremia in asymptomatic infants is low. In neonatal sepsis we can include septicaemia, pneumonia, meningitis, osteomyelitis, and arthritis and urinary tract infections. The burden for neonatal sepsis was 2,202 (95% CI: 1,099–4,360) per 100,000 live births, with mortality between 11% and 19% and more than 40% of under-five deaths occur in the neonatal period, resulting in 3.1 million new-born deaths each year globally. Material and Methods: The total number neonates admitted in the hospital in given study period was 447, of which 198 were diagnosed for neonatal sepsis by the physician based on the signs and symptoms during admission. The data was collected in three parts: sociodemographic characteristics; maternal information; and part neonatal information for neonatal sepsis. Data was collected in the excel sheet and questionnaires were reviewed and organized by investigators. Results: Of the 198 neonates, 162 (81.8%) infants were in the age range of 0 to 7 days while 36 (18.2%) were aged between 8 and 28 days. Statistically significant difference was observed between early onset and late onset sepsis patients. Out of 198 cases 107 (54%) were male while 91(46%) were female. In early onset sepsis cases maternal UTI, Meconium stained amniotic fluid, Multipara and Premature rupture of membrane was seen in 24(14.8%), 21(13.0%), 19(11.7%) and 32 (19.8%) cases respectively. In late onset sepsis cases maternal UTI, Meconium stained amniotic fluid, Multipara and Premature rupture of membrane was seen in 1(2.8%), 2 (5.6%), 4(11.1%) and 2 (5.6%) cases respectively. Maternal risk factors were identified in 104(64.2%) of early onset sepsis cases while maternal risk factors in late onset sepsis cases were 10(27.8%). Culture positivity was observed in 28 (17.3%) cases of early neonatal sepsis while it was 4 (11.1%) in late onset sepsis. Conclusion: There was male preponderance in early as well as late onset neonatal sepsis. Maternal risk identification may help in the early identification and timely empirical antibiotic therapy. The prediction and/ or diagnosis of neonatal sepsis should be bases on culture-independent diagnostics and risk factor-based scoring systems.

scholarly journals Maternal risk factors associated with intrauterine growth restriction: hospital based study

2016 ◽  
Vol 4 (12) ◽  
pp. 2125-2129 ◽  
Author(s):  
Dr. Neetika Ashwani ◽  
◽  
Dr. Aruna Rekha Neela ◽  
Dr. Suresh Babu Mendu ◽  
Dr. Suresh C. Kumar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Intrauterine Growth ◽  
Factors Associated

NEONATAL SEPSIS AND IDENTIFICATION OF RISK FACTORS: STUDY IN AVBRH HOSPITAL SAWANGI

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Pramod P. Singhavi
Keyword(s):  
Risk Factors ◽  
Neonatal Sepsis ◽  
Early Onset ◽  
Late Onset ◽  
Signs And Symptoms ◽  
Premature Rupture ◽  
Maternal Risk ◽  
Late Onset Sepsis ◽  
Early Onset Sepsis ◽  
Meconium Stained Amniotic Fluid

Introduction: India has the highest incidence of clinical sepsis i.e.17,000/ 1,00,000 live births. In Neonatal sepsis septicaemia, pneumonia, meningitis, osteomyelitis, arthritis and urinary tract infections can be included. Mortality in the neonatal period each year account for 41% (3.6 million) of all deaths in children under 5 years and most of these deaths occur in low income countries and about one million of these deaths are due to infectious causes including neonatal sepsis, meningitis, and pneumonia. In early onset neonatal sepsis (EOS) Clinical features are non-specific and are inefficient for identifying neonates with early-onset sepsis. Culture results take up to 48 hours and may give false-positive or low-yield results because of the antenatal antibiotic exposure. Reviews of risk factors has been used globally to guide the development of management guidelines for neonatal sepsis, and it is similarly recommended that such evidence be used to inform guideline development for management of neonatal sepsis. Material and Methods: This study was carried out using institution based cross section study . The total number neonates admitted in the hospital in given study period was 644, of which 234 were diagnosed for neonatal sepsis by the treating pediatrician based on the signs and symptoms during admission. The data was collected: Sociodemographic characteristics; maternal information; and neonatal information for neonatal sepsis like neonatal age on admission, sex, gestational age, birth weight, crying immediately at birth, and resuscitation at birth. Results: Out of 644 neonates admitted 234 (36.34%) were diagnosed for neonatal sepsis by the paediatrician based on the signs and symptoms during admission. Of the 234 neonates, 189 (80.77%) infants were in the age range of 0 to 7 days (Early onset sepsis) while 45 (19.23%) were aged between 8 and 28 days (Late onset sepsis). Male to female ratio in our study was 53.8% and 46% respectively. Out of total 126 male neonates 91(72.2%) were having early onset sepsis while 35 (27.8%) were late onset type. Out of total 108 female neonates 89(82.4%) were having early onset sepsis while 19 (17.6%) were late onset type. Maternal risk factors were identified in 103(57.2%) of early onset sepsis cases while in late onset sepsis cases were 11(20.4%). Foul smelling liquor in early onset sepsis and in late onset sepsis was 10(5.56%) and 2 (3.70%) respectively. In early onset sepsis cases maternal UTI, Meconium stained amniotic fluid, Multipara and Premature rupture of membrane was seen in 21(11.67%), 19 (10.56%), 20(11.11%) and 33 (18.33%) cases respectively. In late onset sepsis cases maternal UTI, Meconium stained amniotic fluid, Multipara and Premature rupture of membrane was seen in 2 (3.70%), 1(1.85%), 3 (5.56%) and 3 (5.56%) cases respectively. Conclusion: Maternal risk identification may help in the early identification and empirical antibiotic treatment in neonatal sepsis and thus mortality and morbidity can be reduced.

First trimester uterine artery Doppler and subsequent intrauterine growth restriction and preterm birth

2004 ◽  
Vol 191 (6) ◽  
pp. S22
Author(s):  
Lorraine Dugoff ◽  
John Hobbins ◽  
Vincent Faber ◽  
Fergal Malone ◽  
Michael Belfort ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Intrauterine Growth Restriction ◽  
Uterine Artery ◽  
First Trimester ◽  
Growth Restriction ◽  
Uterine Artery Doppler ◽  
Intrauterine Growth

scholarly journals UTERINE ARTERY DOPPLER INDICES AS PREDICTIVE MEASURES FOR THE PRE-ECLAMPSIA AND INTRAUTERINE GROWTH RESTRICTION

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
MN Rashid ◽  
M Kari ◽  
R Rashid ◽  
MA Rana ◽  
A Amjad ◽  
...  
Keyword(s):  
Intrauterine Growth Restriction ◽  
Uterine Artery ◽  
Growth Restriction ◽  
Cross Sectional Survey ◽  
Maternal Complications ◽  
Cross Sectional ◽  
Uterine Artery Doppler ◽  
Intrauterine Growth ◽  
Pregnant Females ◽  
Doppler Indices

Preeclampsia and Intrauterine growth restriction (IUGR) remains as the important causes for the neonatal and maternal complications leading to even death in some cases. Uterine artery Doppler USG can be done transvaginally or trans abdominal and performed in the 1st or 2nd trimester of the pregnancy to detect these complications Doppler waveform suggested the high vascular resistance to blood flow. In our present study, we conclude uterine artery Doppler indices as prognostic procedure for the preeclampsia and intrauterine growth restriction. A cross-sectional survey design with convenient sampling technique was used. Mixture of standardized and self-modified structured questionnaire was undertaken to determine the indices of pre eclampsia and IUGR by uterine artery. The data was collected from Bahria International Hospital, Lahore during the period of 9 months. This study was included 162 pregnant females with identification of the main uterine artery on a longitudinal scan lateral to the uterus.  Initial diastolic notch of right and left side of the uterine artery waveforms was recorded. At every antenatal checkup, urine was tested for protein and blood pressure readings were taken to identify preeclampsia. Further analysis was done dividing patients as normotensive and those patients developing hypertension after 30 weeks of gestation. After delivery neonates observed for IUGR by head circumference and body weight. The study was concluded that from the total sample size of 162 pregnant females who undergoes uterine artery Doppler, 34% females shows diastolic notch and almost all of these later diagnosed with preeclampsia and 19.8% deliver babies with IUGR. So, based on the study, we have concluded that uterine artery Doppler is helpful to provide diagnosis of preeclampsia and IUGR in early pregnancy.

Risk Factors for Intrauterine Growth Restriction: 9 Years Analysis in Tertiary Care Hospital

2019 ◽  
Vol 2 (1) ◽  
pp. 77-82
Author(s):  
Abha Shrestha ◽  
N Pradhan ◽  
B Kayastha
Keyword(s):  
Risk Factors ◽  
Intrauterine Growth Restriction ◽  
Tertiary Care ◽  
Adult Life ◽  
Growth Restriction ◽  
Optimal Time ◽  
Care Hospital ◽  
Singleton Pregnancy ◽  
Maternal Risk ◽  
Intrauterine Growth

Background: Intrauterine growth restricted (IUGR) fetuses are at higher risk of developing neonatal complications and also known to develop metabolic syndrome in adult life. So, an early antenatal detection, choosing the optimal time and method of delivery and intervention when required could minimize the risk significantly. Objective: To find out the prenatal outcome and the maternal and placental risk factors. Methods: A prospective study was conducted from January 2010 to January 2019, at a Teaching Hospital. A singleton pregnancy, above 28 weeks of gestation with clinical diagnosis of IUGR and confirmed by ultrasonography were included in the study. The statistical analysis was performed by Statistical Package of Social Sciences (SPSS) 23.0 software. Results: Maternal risk factors like low pregnancy body mass index, preeclampsia, anaemia, hypothyroidism and placental factors like retro placental hemorrhage were mainly responsible for intrauterine growth restriction. Conclusions: The early identification of risk factors and management of the same antenatal is an important issue to prevent adverse prenatal outcomes associated with IUGR.

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