scholarly journals Molecular Characterization of theGhrelinandGhrelin ReceptorGenes and Effects on Fat Deposition in Chicken and Duck

2009 ◽  
Vol 2009 ◽  
pp. 1-12 ◽  
Author(s):  
Q. Nie ◽  
M. Fang ◽  
L. Xie ◽  
X. Peng ◽  
H. Xu ◽  
...  

Ghrelin (GHRL) and its receptor (GHSR) are involved in various bioactivities. In this study, the complete cDNA and5′flanking region of the duckGHRL(dGHRL) gene and a 3717 bp fragment of the duckGHSR(dGHSR) gene were obtained. A total of 19, 8, 43, and 48 SNPs identified in 2751, 1358, 3671, and 3567 bp of the chickenGHRL(cGHRL), chickenGHSR(cGHSR),dGHRL, anddGHSRgenes, respectively. BothcGHRLanddGHRLwere expressed predominantly in the proventriculus, whereas the highest mRNA levels ofcGHSRanddGHSRwere detected in the breast muscle and pituitary. Association analysis showed that C-2047G, A-2355C, and A-2220C of thecGHRLgene were significantly associated with abdominal fat weight (AFW;P=.01), crude protein content of leg muscle (CPCLM;P=.02), and CPCLM (P=.0009), respectively. C-1459T of the cGHSR gene was also significantly associated with CPCLM (P=.0004). C-729T of dGHRL and A3427T of dGHSR were both significantly associated with subcutaneous fat thickness (SFT;P=.04). It was indicated by this study that theGHRLandGHSRgenes were related to fat deposition in both chicken and duck.

1995 ◽  
Vol 75 (2) ◽  
pp. 219-224 ◽  
Author(s):  
J. Zhang ◽  
D. G. Grieve ◽  
B. L. Coomber

Weaned female lambs were used to study the effects of dietary protein (15 or 20%) and β-agonist (L-644,969: 0 mg kg−1 or 1 mg kg−1) on fat deposition between weaning and puberty. Lambs were fed pelleted concentrate plus 200 g hay d−1 to achieve a target weight gain of 260 g d−1. The trial continued for 102 d with dietary protein treatment starting on day 1 and β-agonist starting on day 20. Comparisons were made between the two levels in each of the two factors when there was no interaction. Carcass fat was reduced by 19.1% (P < 0.01) and carcass protein was increased by 15.8% (P < 0.01) in lambs fed the β-agonist. Carcass fat and protein were not affected by dietary protein. There was a nonsignificant trend to lower kidney-pelvic fat and subcutaneous fat thickness with the β-agonist (P > 0.1). Treatment did not affect the total mammary-gland weight, expressed as a proportion of final body weight. Neither the diameter nor the number of fat cells in kidney–pelvic fat and the MGFP were affected by dietary protein or β-agonist. Results indicate that the β-agonist is effective in the control of fat deposition other than that in the MGFP in rapidly growing female lambs. However, there was no apparent effect of dietary protein on adipose tissues. Key words: Lambs, β-agonist, dietary protein, fat deposition


2014 ◽  
Author(s):  
Ozen Oz Gul ◽  
Murat Pekgoz ◽  
Sumeyye Gullulu ◽  
Soner Cander ◽  
Ahmet Tutuncu ◽  
...  

1988 ◽  
Vol 59 (4) ◽  
pp. 335-343
Author(s):  
Yoshitaka NAGAMINE ◽  
Takashi HAYASHI ◽  
Hiroshi SATO ◽  
Akira NISHIDA ◽  
Shigeki KOMATSU

2021 ◽  
pp. 104694
Author(s):  
Francisco Fernandes Junior ◽  
Amanda de Freitas Pena ◽  
Fernando Augusto Grandis ◽  
Natalia Albieri Koritiaki ◽  
Fabíola Cristine de Almeida Rego ◽  
...  

Author(s):  
Thomas Fiala

Abstract Background A novel FDA-cleared device uses a 1064 nm laser to non-invasively induce apoptosis for lipolysis of subcutaneous abdominal fat while maintaining comfortable skin temperatures with a proprietary jet cooling system (eon ®, Dominion Aesthetic Technologies, Inc.; San Antonio, TX). A programmable articulated robotic arm moves the treatment head without any subject contact, maintaining an appropriate three-dimensional treatment path, compensating for patient movement. Objectives The goal of this prospective, single center, open-label study was to demonstrate the safety and effectiveness of this device for reducing subcutaneous abdominal fat using an updated power delivery curve. Methods Male and female subjects with Fitzpatrick skin types I-VI (N=26) were treated. Four abdominal zones up to 150 cm 2 each, customized in size and location for body habitus were treated. Each zone underwent a single 20-minute treatment session. Follow-up visits occurred after 6 and 12 weeks. Using a standardized protocol, ultrasound measurement of subcutaneous abdominal fat thickness, abdominal circumference, reported patient satisfaction and digital images were obtained. Results The mean treatment area was 378.5 cm 2. At Week 12, there was a 21.6% mean reduction in abdominal subcutaneous fat thickness and a 4.1-cm (1.6-inch) mean reduction in abdominal circumference. Most subjects (84.6%) were satisfied or very satisfied with their results. The mean pain score was 2.5 on an 11-point ordinal scale. There were no non-responders. Only two adverse events were noted: mild transient erythema (n=1, 3.8%) and localized subcutaneous firmness (n=1, 3.8%) which resolved without intervention within 12 weeks. Conclusions This contact-free device is safe and effective for reducing subcutaneous abdominal fat and represents an improvement on the prior treatment protocol.


2012 ◽  
Vol 41 (6) ◽  
pp. 1426-1432 ◽  
Author(s):  
Tiago Roque Pinheiro ◽  
Maria Eugênia Zerlotti Mercadante ◽  
Lucia Galvão de Albuquerque ◽  
Sarah Figueiredo Martins Bonilha ◽  
Fábio Morato Monteiro

1992 ◽  
Vol 72 (4) ◽  
pp. 1589-1594 ◽  
Author(s):  
J. Smolander ◽  
O. Bar-Or ◽  
O. Korhonen ◽  
J. Ilmarinen

Eight minimally dressed pre- and early pubescent boys (age 11–12 yr) and 11 young adult men (age 19–34 yr) rested for 20 min and exercised on a cycle ergometer for 40 min at approximately 30% of their maximum oxygen consumption (VO2max) at 5 degrees C. To quantify the added increase in metabolic rate because of cold, a separate test was carried out at 21 degrees C at rest and at equal work rates as in the cold. Both groups were similar in subcutaneous fat thickness and VO2max per kilogram body weight. Rectal temperature increased slightly during the exposure to the cold, but no significant difference was observed between the boys and men. In the cold, the boys had lower skin temperatures than the adults in their extremities but not in the trunk. The boys increased their metabolic rates in the cold more than did the men. As a result, the boys maintained their core temperature as effectively as the adults. Similar age-related differences in thermoregulatory responses to cold were observed when two boys and two men with equal body sizes were compared. Our results suggest that there may be maturation-related differences in thermoregulation in the cold between children and adults.


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