Structural characterization and DNA-binding properties of Sm(III) complex with ofloxacin using spectroscopic methods
2009 ◽
Vol 23
(2)
◽
pp. 103-111
◽
A novel complex Sm(III) complex with ofloxacin was synthesized and characterized on the basis of elemental analyses, molar conductivities, IR spectra, thermal analysis (TG-DSC),1H-NMR spectra. Then, spectrometric titration, ethdium bromide displacement experiments by UV spectroscopy, ionic influence, viscosity measurements and Circular Dichroism (CD) spectroscopic measurements were conducted to characterize the interaction between the complex and CT-DNA. Results obtained indicate that the complex bound with CT-DNA via an intercalation mechanism. The binding constants and binding sites number of the Sm(III) complex with CT-DNA were 1.80×105l·mol−1and 1, respectively.
1995 ◽
Vol 60
(5)
◽
pp. 903-909
◽
2014 ◽
Vol 2014
◽
pp. 1-7
◽
2011 ◽
Vol 2011
◽
pp. 1-11
◽
2006 ◽
Vol 10
(02)
◽
pp. 117-121
◽
2010 ◽
Vol 65
(11)
◽
pp. 1341-1348
◽