Synthesis, Spectral Characterization and Antimicrobial Evaluation of Schiff Base Cu(II), Ni(II) and Co(II) Novel Macrocyclic Complexes

A series of Schiff base macrocyclic complexes of the type [HLMX2] where M = Cu(II), Ni(II), Co(II) and X = Cl, OAc have been synthesized by condensation of acetylacetone and thiocarbohydrazide (2:2) in the presence of divalent metal salt in methanolic medium. The complexes have been characterized with the help of elemental analysis, conductance measurements, magnetic measurements and their structural configuration have been determined by various spectroscopic (Electronic, IR,1H NMR,13C NMR, GCMS) techniques. Electronic and magnetic moments of the complexes indicate that the geometries of the metal centers are octahedral. These metal complexes were also tested for their antimicrobial activities to assess their inhibiting potential.

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Synthesis and Spectral Characterization of Schiff Base Cr(III), Mn(III), and Fe(III) Novel Macrocyclic Complexes Derived from Thiocarbohydrazide and Dicarbonyl Compound

E-Journal of Chemistry ◽

10.1155/2012/956812 ◽

2012 ◽

Vol 9 (4) ◽

pp. 2255-2260 ◽

Cited By ~ 3

Author(s):

Gajendra Kumar ◽

Shoma Devi ◽

Rajeev Johari

Keyword(s):

Schiff Base ◽

Magnetic Measurements ◽

Metal Salt ◽

Magnetic Moments ◽

Macrocyclic Complexes ◽

Dicarbonyl Compound ◽

Metal Centers ◽

H Nmr ◽

C Nmr

M(III) Schiff base macrocyclic complexes of the type [HLMX2] where M = Cr(III), Mn(III), Fe(III) and X = Cl, OAc have been synthesized by condensation of acetylacetone and Thio-carbohydrazide (2:2) in the presence of divalent metal salt in methanolic medium. The complexes have been characterized with the help of elemental analysis, conductance measurements, magnetic measurements and their structural configuration have been determined by various spectroscopic (electronic, IR,1H NMR,13C NMR, GCMS) techniques. Electronic and magnetic moments of the complexes indicate that the geometries of the metal centers are octahedral.

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Synthesis, Physical Characterization of M(III) Transition Metal Complexes Derived from Thiodihydrazide and 5-tert-Butyl-2-hydroxy-3-(3-phenylpent-3-yl) Benzaldehyde

E-Journal of Chemistry ◽

10.1155/2012/817051 ◽

2012 ◽

Vol 9 (4) ◽

pp. 2119-2127 ◽

Cited By ~ 3

Author(s):

Gajendra Kumar ◽

Rajeev Johari ◽

Shoma Devi

Keyword(s):

Schiff Base ◽

Metal Complexes ◽

Schiff Base Ligand ◽

Metal Ion ◽

Magnetic Measurements ◽

Metal Salt ◽

Magnetic Moments ◽

Metal Centers ◽

H Nmr

A Schiff base ligand was synthesized by reacting 5-tert-butl-2-hydroxy-3-(3-phenylpent-3-yl) benzaldehyde and thiodihydrazide (2:1) and a series of metal complexes with this new ligand were synthesized by reaction with Cr (III), Mn (III), and Fe (III) metal salt in methanolic medium. The Schiff base ligand and its complexes have been characterized with the help of elemental analysis, conductance measurements, magnetic measurements and their structure configuration have been determined by various spectroscopic (electronic, IR,1H NMR,13C NMR, GCMS) techniques. Electronic and magnetic moments of the complexes indicate that the geometries of the metal centers were octahedral. IR spectral data suggest that ligand behaves as a tetradentate ligand with ONNO donor sequence towards the metal ion.

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Synthesis, Antimicrobial Evaluation of Substituted Indole and Nitrobenzenamine based Cr(III), Mn(III) and Fe(III) Metal Complexes

Drug Research ◽

10.1055/a-1527-1307 ◽

2021 ◽

Author(s):

Preeti Sharma ◽

Varun Kumar Singh ◽

Gajendra Kumar

Keyword(s):

Schiff Base ◽

Metal Complexes ◽

Schiff Base Ligand ◽

Magnetic Measurements ◽

Magnetic Moments ◽

Salmonella Typhi ◽

Antimicrobial Activities ◽

Antimicrobial Evaluation ◽

Aspergillus Sp ◽

Bacteria And Fungi

AbstractSchiff base ligand (E)-5-methyl-3-(1-(4-nitrophenylimino)ethyl)-1H-indol-2-amine was synthesized by the condensation of 1-(2-amino-5-methyl-1H-indol-3-yl)ethanone and 4-nitrobenzenamine in methanol at 70 oC. The prepared Schiff base ligand doped with Cr(III), Mn(III) and Fe(III) ion, respectively and it is denoted as [M(C34H32N8O4)X]X2. The complexes have been characterized with the help of elemental analysis, conductance measurements, magnetic measurements and their structural configuration have been determined by various spectroscopic (electronic, IR, 1H NMR, 13C NMR, GCMS) techniques. Electronic and magnetic moments of the complexes indicate that the geometry of the metal center was five coordinate square pyramidal. These metal complexes were also tested for their antimicrobial activities to assess their inhibiting potential against Staphylococcus aureus, Bacillus subtilis (positive bacteria) and Pseudomonas aeruginosa, Escherichia coli, Salmonella typhi (negative bacteria) and fungi Rizoctonia sp., Aspergillus sp., Penicillium sp. [Cr(C34H32N8O4)OAc](OAc)2 shows best antimicrobial activity against all the pathogens.

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Synthesis, Spectroscopic, and Magnetic Studies of Mono- and Polynuclear Schiff Base Metal Complexes Containing Salicylidene-Cefotaxime Ligand

International Journal of Inorganic Chemistry ◽

10.1155/2013/108740 ◽

2013 ◽

Vol 2013 ◽

pp. 1-7 ◽

Cited By ~ 5

Author(s):

J. R. Anacona ◽

Johan Calvo ◽

Ovidio A. Almanza

Keyword(s):

Schiff Base ◽

Metal Complexes ◽

Schiff Base Ligand ◽

Magnetic Moments ◽

Spectral Studies ◽

Magnetic Studies ◽

H Nmr ◽

Uv Visible ◽

Schiff Base Metal Complexes ◽

C Nmr

Metal complexes of a Schiff base ligand derived from cefotaxime and salicylaldehyde were prepared. The salicilydene-cefotaxime ligand (H2L) and mononuclear [M(L)] (M(II) = Co, Ni and Cu), dinuclear [Ag2(L)(OAc)2], and tetranuclear metal complexes [M4(L)(OH)6] (M(II) = Ni, Cu) were characterized on the basis of analytical, thermal, magnetic, and spectral studies (IR, UV-visible, 1H NMR, 13C NMR, and EPR). The electronic spectra of the complexes and their magnetic moments suggesttetrahedral geometry for the isolated complexes. The complexes are nonelectrolytes and insoluble in water and common organic solvents but soluble in DMSO.

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Synthesis, characterization, and antimicrobial activities of novel double-armed benzo-15-crown-5 and their sodium and potassium complexes

Journal of Chemical Research ◽

10.1177/1747519820932264 ◽

2020 ◽

pp. 174751982093226

Author(s):

Öznur Şener Cemaloğlu ◽

Hatice Ogutcu ◽

Zeliha Hayvalı

Keyword(s):

Schiff Base ◽

Crown Ether ◽

Mass Spectra ◽

Sodium Perchlorate ◽

Antimicrobial Activities ◽

Pathogenic Microorganisms ◽

Inhibitory Effects ◽

Antibacterial Effects ◽

Sodium And Potassium ◽

C Nmr

New aldehyde- and halogen- (Cl, Br, I) substituted double-armed benzo-15-crown-5 derivatives are synthesized by the reactions of 4′,5′-bis(bromomethyl)benzo-15-crown-5 with 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, or 5-iodosalicylaldehyde. The sodium and potassium complexes are obtained by reaction of crown ether with sodium perchlorate and potassium iodide, respectively. Novel Schiff base compounds containing three groups of benzo-15-crown-5 are obtained from the condensation of aldehydes with 4′-aminobenzo-15-crown-5. The structures of all compounds are elucidated by elemental analysis, 1H, 13C NMR, IR, and mass spectra. The antifungal and antibacterial effects of the synthesized ligands are evaluated against pathogenic microorganisms and show varying degrees of inhibitory effects against the growth of different pathogenic strains. Graphical abstract

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Synthesis of cis, cis-1,3,5-trisubstituted cyclohexane based chelators with polyfunctional pendant arms

Journal of Chemical Research ◽

10.3184/0308234053431149 ◽

2005 ◽

Vol 2005 (1) ◽

pp. 43-45 ◽

Cited By ~ 3

Author(s):

Minati Baral ◽

B.K. Kanungo ◽

Peter Moore

Keyword(s):

Schiff Base ◽

Nmr Spectroscopy ◽

Organic Compounds ◽

Elemental Analysis ◽

H Nmr ◽

Benzenetricarboxylic Acid ◽

New Compounds ◽

Pendant Arms ◽

C Nmr

Some novel organic compounds of the type: cis, cis-1,3,5-tris(X)cyclohexane, where X= –CONH(CH2)2NH2, –CONH(CH2)3NH2, –CONH(CH2)2NCH –C6H4OH, CONH(CH2)3NCHC6H4OH, which are expected to function as potential polydentate chelators have been synthesised from 1,3,5-benzenetricarboxylic acid through multi-steps reactions. 1,3,5-benzenetricarboxylic acid was reduced to cis, cis-1,3,5-tris(ethylcarboxylate)cyclohexane, which on reaction with excess of 1,2-diaminoethane and 1,2-diaminopropane afforded two new compounds. Condensation of the obtained derivatives with three equivalents of salicylaldehyde resulted the formation of two new Schiff base compounds. All the compounds were characterised by a combination of elemental analysis, mass, IR, UV-Vis, 1H NMR and 13C NMR spectroscopy.

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Characteristic Studies of Hexamethylene Diamine Complexes

International Journal of Inorganic Chemistry ◽

10.1155/2013/458018 ◽

2013 ◽

Vol 2013 ◽

pp. 1-12

Author(s):

Hoda A. Bayoumi

Keyword(s):

Electrical Conductivity ◽

Schiff Base ◽

Thermogravimetric Analysis ◽

Chemical Analysis ◽

Magnetic Measurements ◽

Molar Conductance ◽

Semiconductor Materials ◽

Ortho Position ◽

Hexamethylene Diamine ◽

H Nmr

Preparation and chemical analysis of Mn(II), Fe(III), Co(II), Ni(II), and Zn(II) complexes with Schiff base L [o-HOC6H4CH:N(CH2)6N:CHC6H4OH-o] are the main tasks of this work. The octahedral (M2L2·nH2O·X) complexes in 1 : 1 M : L ratio (X = NO3− or Ac− group, L = ligand) were prepared by involving the hydroxylic group in ortho position. All complexes were characterized on the basis of elemental analysis, UV, IR, 1H NMR, Gc/Ms, thermogravimetric analysis, magnetic measurements, molar conductance, and electrical conductivity. The obtained data indicate that all the investigated compounds behave as semiconductor materials.

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Synthesis, Spectral and Microbial Studies of Some Novel Schiff Base Derivatives of 4-Methylpyridin-2-amine

E-Journal of Chemistry ◽

10.1155/2009/247209 ◽

2009 ◽

Vol 6 (4) ◽

pp. 1205-1210 ◽

Cited By ~ 3

Author(s):

J. J. Vora ◽

S. B. Vasava ◽

K. C. Parmar ◽

S. K. Chauhan ◽

S. S. Sharma

Keyword(s):

Schiff Base ◽

Antimicrobial Activities ◽

Dilution Method ◽

Mass Spectral ◽

H Nmr ◽

Schiff Base Derivatives ◽

Ft Ir ◽

Acid Catalyzed ◽

Derivatives Of ◽

Broth Dilution

Schiff base derivatives ofN-{(1E)-[3-(mono or di-substituted aryl)-1-phenyl-1H-pyrazol-4-yl]methylene{-4-methylpyridin-2-amine were synthesized by the acid catalyzed condensation of 3-(mono- or di- substituted aryl)-1-phenyl-1H-pyrazole-4-carbaldehyde derivatives with 4-methylpyridin-2-amine. Schiff base derivatives were characterized by FT-IR,1H-NMR, Mass spectral analysis and elemental analysis. All the synthesized compounds have been screened for their antimicrobial activities by using broth dilution method.

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Synthesis, structure, and electrochemistry of cobalt(III) complexes with bis(benzoylacetone)ethylenediimine Schiff base

Canadian Journal of Chemistry ◽

10.1139/v02-122 ◽

2002 ◽

Vol 80 (9) ◽

pp. 1196-1203 ◽

Cited By ~ 25

Author(s):

Mehdi Amirnasr ◽

Rasoul Vafazadeh ◽

Amir H Mahmoudkhani

Keyword(s):

Schiff Base ◽

Reduction Potential ◽

Crystal And Molecular Structure ◽

Acetonitrile Solution ◽

Potential Range ◽

Carbon Electrode ◽

X Ray ◽

X Ray Crystallography ◽

H Nmr ◽

C Nmr

A series of complexes of the type trans-[Co((BA)2en)(amine)2]ClO4 where (BA)2en is the bis(benzoylacetone)ethylenediimine dianion and the amines are morpholine (mrpln) 1, aniline (aniln) 2, benzylamine (bzlan) 3, piperidine (pprdn) 4, p-toluidine (p-toldn) 5, and pyrrolidine (prldn) 6 has been synthesized and characterized by elemental analysis, UVvis, 1H NMR, and 13C NMR spectroscopy. The crystal and molecular structure of trans-[Co((BA)2en)(mrpln)2]ClO4 (1) has been determined by X-ray crystallography. The electrochemical reduction of these complexes at a glassy-carbon electrode, in the potential range of 0.5 to 2.0 V (vs. Ag/AgCl), in acetonitrile solution, indicates that the first reduction potential of Co(III/II) is irreversible, which is accompanied by the dissociation of the axial aminecobalt bonds. This potential is dependent on the pKa of the axial amines. The second reduction potential of Co(II/I) shows reversible behavior and is also independent of the axial amine pKa. These results indicate the loss of the axial amines in the first redox process and the involvement of a four-coordinate species in the second redox step.Key words: Schiff base, cobalt(III), axial amine, electrochemical properties, crystal structure.

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Coordination Modes of a Schiff Base Derived from Substituted 2-Aminothiazole with Chromium(III), Manganese(II), Iron(II), Cobalt(II), Nickel(II) and Copper(II) Metal Ions: Synthesis, Spectroscopic and Antimicrobial Studies

E-Journal of Chemistry ◽

10.1155/2011/282061 ◽

2011 ◽

Vol 8 (4) ◽

pp. 1750-1764 ◽

Cited By ~ 4

Author(s):

Ambit Thakar ◽

Krishnakant Joshi ◽

Kishor Pandya ◽

Arvind Pancholi

Keyword(s):

Schiff Base ◽

Metal Ions ◽

Transition Metal Complexes ◽

Mass Spectra ◽

Antibacterial Activities ◽

Molar Conductance ◽

Spectral Techniques ◽

H Nmr ◽

Antimicrobial Studies ◽

C Nmr

Transition metal complexes of Cr(III), Mn(II), Fe(II), Co(II), Ni(II) and Cu(II) metal ions with general stoichiometry [ML2.2H2O] and [ML3], where M= Mn(II), Cr(III), Fe(II), Co(II), Ni(II) and Cu(II), L= Schiff base derived from the condensation of 2-amino-4(4’-phenyl/methylphenyl)-5-methyl-thiazole with 4-acetyl-1(3-chloro phenyl)-3-methyl-2-pyrazoline-5-ones, have been synthesized and structurally characterized by elemental analysis, molar conductance measurements, magnetic susceptibility measurements and spectral techniques like IR, UV,1H NMR,13C NMR and Mass Spectra. All the complexes were found to be octahedral geometry. The ligand and its complexes have been screened for their antifungal and antibacterial activities against three fungi,i.e. Alternaria brassicae, Aspergillus nigerandFesarium oxysporumand two bacteria,i.e. Xanthomonas compestrisandPseudomonas aeruginosa.

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