scholarly journals A Systematic Review of the Effectiveness of Knowledge Translation Interventions for Chronic Noncancer Pain Management

2013 ◽  
Vol 18 (6) ◽  
pp. e129-e141 ◽  
Author(s):  
Maria B Ospina ◽  
Paul Taenzer ◽  
Saifee Rashiq ◽  
Joy C MacDermid ◽  
Eloise Carr ◽  
...  
Keyword(s):  
Systematic Review ◽  
Pain Management ◽  
Knowledge Translation ◽  
Risk Of Bias ◽  
Care Providers ◽  
Chronic Noncancer Pain ◽  
Positive Effects ◽  
Interactive Education ◽  
Study Results ◽  
Noncancer Pain

BACKGROUND: Reliable evidence detailing effective treatments and management practices for chronic noncancer pain exists. However, little is known about which knowledge translation (KT) interventions lead to the uptake of this evidence in practice.OBJECTIVES: To conduct a systematic review of the effectiveness of KT interventions for chronic noncancer pain management.METHODS: Comprehensive searches of electronic databases, the gray literature and manual searches of journals were undertaken. Randomized controlled trials, controlled clinical trials and controlled before-and-after studies of KT interventions were included. Data regarding interventions and primary outcomes were categorized using a standard taxonomy; a risk-of-bias approach was adopted for study quality. A narrative synthesis of study results was conducted.RESULTS: More than 8500 titles and abstracts were screened, with 230 full-text articles reviewed for eligibility. Nineteen studies were included, of which only a small proportion were judged to be at low risk of bias. Interactive KT education for health care providers has a positive effect on patients’ function, but its benefits for other health provider- and patient-related outcomes are inconsistent. Interactive education for patients leads to improvements in knowledge and function. Little research evidence supports the effectiveness of structural changes in health systems and quality improvement processes or coordination of care.CONCLUSIONS: KT interventions incorporating interactive education in chronic noncancer pain led to positive effects on patients’ function and knowledge about pain. Future studies should provide implementation details and use consistent theoretical frameworks to better estimate the effectiveness of such interventions.

Iatrogenic addiction or dependence as a result of prescription oxycodone use in persons with chronic noncancer pain: A systematic review

2021 ◽  
Vol 17 (1) ◽  
pp. 79-96
Author(s):  
Megan Dol, BSc ◽  
Mark Oremus, PhD
Keyword(s):  
Systematic Review ◽  
Data Extraction ◽  
Cochrane Collaboration ◽  
Incidence Rates ◽  
Risk Of Bias ◽  
Cochrane Library ◽  
Eligibility Criteria ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

Objective: To determine the incidence of addiction and dependence in persons with chronic noncancer pain (CNCP) who are treated with oxycodone.Design: Systematic review following PRISMA guidelines.Methods: PubMed, MEDLINE, EMBASE, CINAHL, PsycINFO, and Cochrane Library were searched from inception to January 2020. Of 1,320 retrieved citations screened by two independent raters at title and abstract and full-text screening, six articles fulfilled the eligibility criteria for the systematic review. Data extraction and risk of bias assessment followed article screening. The Cochrane Collaboration tool and the Newcastle-Ottawa Scale (NOS) were used to assess the risk of bias in individual studies.Results: Two of the six articles reported addiction and the remaining four reported dependence. The incidence rates of addiction were 2.91 percent and 1.72 percent, and the incidence rates of dependence were 0.00 percent, 0.44 percent, 0.45 percent, and 5.77 percent. In all articles, addiction and dependence were treated as secondary outcomes. Three randomized controlled trials (RCTs) had follow-up lengths of less than 31 days, which is insufficient to assess the incidence of addiction or dependence.Conclusions: The results of this systematic review show that oxycodone use leads to addiction and dependence in a small proportion of individuals with CNCP. However, one must exercise caution when drawing conclusions from the six included articles. Future studies in the area should examine addiction and dependence as primary outcomes using adequate follow-up periods.

Prescriber adherence to guidelines for chronic noncancer pain management with opioids: Systematic review and meta-analysis.

2020 ◽  
Vol 39 (5) ◽  
pp. 430-451 ◽  
Author(s):  
Mohammad A. Hossain ◽  
Michael Asamoah-Boaheng ◽  
Oluwatosin A. Badejo ◽  
Louise V. Bell ◽  
Norman Buckley ◽  
...  
Keyword(s):  
Systematic Review ◽  
Pain Management ◽  
Meta Analysis ◽  
Adherence To Guidelines ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

The Prevalence of Opioid Analgesic Use in People with Chronic Noncancer Pain: Systematic Review and Meta-Analysis of Observational Studies

Pain Medicine ◽  
2020 ◽  
Author(s):  
Graeme Wertheimer ◽  
Stephanie Mathieson ◽  
Christopher G Maher ◽  
Chung-Wei Christine Lin ◽  
Andrew J McLachlan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Observational Studies ◽  
Opioid Analgesic ◽  
Risk Of Bias ◽  
Opioid Use ◽  
Chronic Noncancer Pain ◽  
Moderate Quality ◽  
Meta Regression ◽  
Noncancer Pain ◽  
Quality Evidence

Abstract Objective To review studies examining the proportion of people with chronic noncancer pain who report consuming opioids and characteristics associated with their use. Design Systematic review. Methods We searched databases from inception to February 8, 2020, and conducted citation tracking. We included observational studies reporting the proportion of adults with chronic noncancer pain who used opioid analgesics. Opioids were categorized as weak (e.g., codeine) or strong (e.g., oxycodone). Study risk of bias was assessed, and Grading of Recommendations Assessment, Development and Evaluations provided a summary of the overall quality. Results were pooled using a random-effects model. Meta-regression determined factors associated with opioid use. Results Sixty studies (N=3,961,739) reported data on opioid use in people with chronic noncancer pain from 1990 to 2017. Of these 46, 77% had moderate risk of bias. Opioid use was reported by 26.8% (95% confidence interval [CI], 23.1–30.8; moderate-quality evidence) of people with chronic noncancer pain. The use of weak opioids (17.3%; 95% CI 11.9–24.4; moderate-quality evidence) was more common than the use of strong opioids (9.8%; 95% CI, 6.8–14.0; low-quality evidence). Meta-regression determined that opioid use was associated with geographic region (P=0.02; lower in Europe than North America), but not sampling year (P=0.77), setting (P=0.06), diagnosis (P=0.34), or disclosure of funding (P=0.77). Conclusions Our review summarized data from over 3.9 million people with chronic noncancer pain reporting their opioid use. Between 1990 and 2017, one-quarter of people with chronic noncancer pain reported taking opioids, and this proportion did not change over time.

Are Physicians Safely Prescribing Opioids for Chronic Noncancer Pain? A Systematic Review of Current Evidence

Pain Practice ◽  
2015 ◽  
Vol 16 (3) ◽  
pp. 370-383 ◽  
Author(s):  
Juliana Tournebize ◽  
Valérie Gibaja ◽  
Amandine Muszczak ◽  
Jean-Pierre Kahn
Keyword(s):  
Systematic Review ◽  
Current Evidence ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

scholarly journals Interventions to improve healthcare workers’ hand hygiene compliance: A systematic review of systematic reviews

2018 ◽  
Vol 39 (12) ◽  
pp. 1449-1456 ◽  
Author(s):  
Lesley Price ◽  
Jennifer MacDonald ◽  
Lucyna Gozdzielewska ◽  
Tracey Howe ◽  
Paul Flowers ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hand Hygiene ◽  
Systematic Reviews ◽  
Hand Hygiene Compliance ◽  
Educational Interventions ◽  
Risk Of Bias ◽  
Future Research ◽  
Monitoring Technology ◽  
Positive Effects ◽  
Hygiene Compliance

AbstractObjectiveTo synthesize the existing evidence base of systematic reviews of interventions to improve healthcare worker (HCW) hand hygiene compliance (HHC).MethodsPRISMA guidelines were followed, and 10 information sources were searched in September 2017, with no limits to language or date of publication, and papers were screened against inclusion criteria for relevance. Data were extracted and risk of bias was assessed.ResultsOverall, 19 systematic reviews (n=20 articles) were included. Only 1 article had a low risk of bias. Moreover, 15 systematic reviews showed positive effects of interventions on HCW HHC, whereas 3 reviews evaluating monitoring technology did not. Findings regarding whether multimodal rather than single interventions are preferable were inconclusive. Targeting social influence, attitude, self-efficacy, and intention were associated with greater effectiveness. No clear link emerged between how educational interventions were delivered and effectiveness.ConclusionsThis is the first systematic review of systematic reviews of interventions to improve HCW HHC. The evidence is sufficient to recommend the implementation of interventions to improve HCW HHC (except for monitoring technology), but it is insufficient to make specific recommendations regarding the content or how the content should be delivered. Future research should rigorously apply behavior change theory, and recommendations should be clearly described with respect to intervention content and how it is delivered. Such recommendations should be tested for longer terms using stronger study designs with clearly defined outcomes.

scholarly journals Does pre-notification increase questionnaire response rates: a nested randomised control trial

2021 ◽  
Author(s):  
Benjamin Woolf ◽  
Phil Edwards
Keyword(s):  
Systematic Review ◽  
Response Rates ◽  
Risk Of Bias ◽  
Randomised Control Trial ◽  
Questionnaire Response ◽  
Potential Study ◽  
Study Results ◽  
Study Participants ◽  
Unclear Risk

AbstractBackgroundStudy results can be badly affected by non-response. One way to potentially reduce non-response is by sending potential study participants advance communication. During the update of a systematic review examining the effect of pre-notification on response rates, a number of study authors needed to be contacted for further information.ObjectivesTo conduct an RCT to investigate the effect of pre-notification, nested within the request for further information for a systematic review.MethodsStudy authors included in the systematic review, whose studies were at unclear risk of bias, and who were contactable, were randomly sent or not set a pre-notification email prior to being sent the request for further information email.ResultsAt the end of follow up, 14/33 (42.4%) authors in the pre-notification condition had returned responses to the questionnaire, and 18/42 (42.9%). There was not evidence of a difference between these groups.ConclusionsThis study’s results do not support the hypothesis that pre-notification does increase response from participants.

scholarly journals Outcomes Associated with Opioid Use in the Treatment of Chronic Noncancer Pain in Older Adults: A Systematic Review and Meta-Analysis

2010 ◽  
Vol 58 (7) ◽  
pp. 1353-1369 ◽  
Author(s):  
Maria Papaleontiou ◽  
Charles R. Henderson Jr ◽  
Barbara J. Turner ◽  
Alison A. Moore ◽  
Yelena Olkhovskaya ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Meta Analysis ◽  
Opioid Use ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain
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