scholarly journals Acute Effects of an Energy Drink on Myocardial Function Assessed by Conventional Echo-Doppler Analysis and by Speckle Tracking Echocardiography on Young Healthy Subjects

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Daniele Menci ◽  
Francesca Maria Righini ◽  
Matteo Cameli ◽  
Matteo Lisi ◽  
Susanna Benincasa ◽  
...  

Purpose. Previous studies have underlined the effects of the energy drinks containing caffeine end taurine on the cardiovascular system. The aim of this study was to determine acute changes on echocardiographic parameters assessed by conventional echo-Doppler analysis and by speckle tracking echocardiography after the consumption of an energy drink in a young healthy population. Methods. measurement of blood pressure, electrocardiographic, and echocardiographic examination were performed on 35 healthy subjects (mean age 25 ± 2 years, 16 men), at baseline and one hour after the consumption of a body surface area indexed amount of an energy drink (168 mL/m2) containing caffeine (0.03%) and taurine (0.4%). Results. The analysis of left ventricular function showed a significant increase of mean relative values of MAPSE (+11%; ), global longitudinal strain (+10%, ), and left ventricular twisting (+22%, ) in respect to baseline. Also, right ventricular function parameters appeared significantly increased after energy drink consumption, as TAPSE (+15%, ), global, and free wall right ventricular longitudinal strain (+8%, ; +5%, , resp.). Conclusion. In conclusion, the consumption of the ED in our population showed a significant increase of right and left ventricular myocardial function, suggesting a possible positive inotropic effect related to the substances contained therein.

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1578
Author(s):  
Ryohei Suzuki ◽  
Yunosuke Yuchi ◽  
Haruka Kanno ◽  
Takahiro Teshima ◽  
Hirotaka Matsumoto ◽  
...  

The endomyocardial form of restrictive cardiomyopathy (EMF-RCM), a primary disorder of the myocardium, is one of the diseases with poor prognosis in cats. We hypothesized that both the left and right myocardial functional abnormalities may occur in cats with EMF-RCM, causing this disease pathophysiology and clinical status. Out of the 25 animals included in this study, 10 were client-owned cats with EMF-RCM, and 15 were healthy cats. In this study, cats were assessed for layer-specific myocardial function (whole, endocardial, and epicardial) in the left ventricular longitudinal and circumferential directions, and right ventricular longitudinal direction, via two-dimensional speckle-tracking echocardiography (2D-STE). Cats with EMF-RCM had depressed left ventricular myocardial deformations both in systole (whole longitudinal strain, epicardial longitudinal strain, and endocardial circumferential strain) and diastole (early and late diastolic longitudinal strain rates, and late diastolic circumferential strain rate) compared to controls. Furthermore, some right ventricular myocardial deformations (systolic longitudinal strain in epicardial layers, and endocardial-to-epicardial strain ratio) were significantly differerent in cats with EMF-RCM. Myocardial function assessed by 2D-STE could reveal left and right myocardial dysfunction.


2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
W W Chen ◽  
Q B Zhu ◽  
E L Posada-Martinez ◽  
X A Ortiz-Leon ◽  
J Pereira ◽  
...  

Abstract Funding Acknowledgements No. OnBehalf No. Background The immediate effect on myocardial function and deformation after coronary revascularization is incompletely studied. Effective revascularization along with perioperative myocardial injury compromises improved regional and global left ventricular function and leads to the risks of adverse perioperative events following coronary artery bypass grafting (CABG) surgery. Global longitudinal strain (GLS) assessed by speckle-tracking echocardiography (STE) has been reported as a better predictor and a more sensitive marker for postoperative ventricular remodeling. Purpose This study aimed to evaluate changes of left ventricular (LV) systolic function and GLS in the perioperative period during CABG and to investigate the value of GLS using two-dimensional STE in predicting short-term outcome. Methods A total of 22 patients who underwent elective CABG surgery (EuroSCORE II 1.84 ± 1.2) were evaluated. Transesophageal echocardiography was performed, 2D and three-dimensional echocardiography (3DE) data was acquired before sternotomy, before cardiopulmonary bypass (CPB), after bypass and after chest closure. LV GLS and tissue motion annular displacements (TMAD) of the mitral valves were quantified by 2D STE using CMQ software. LV volumes and ejection fraction (EF) were evaluated by 3DE at the same timepoints. Short-term outcomes were defined as death, stroke, myocardial infarction, acute kidney dysfunction, rehospitalization and repeated revascularization in a one-month period after surgery. Results Both 2D and 3DE of all patients were analyzed. The cohort had a mean age of 68.2 ± 7.2 years and 9.1% was women. Before sternotomy, GLS was -15.7 ± 2.9%. Despite little change in 3D LVEF, GLS was immediately impaired after coronary artery bypass graft (before bypass vs after chest closure, -15.9 ± 3.6% vs -13.5 ± 4.0%, P = 0.001). There was strong correlation between GLS and 3D LVEF (r=-0.77, P < 0.001), moderate correlations between GLS and absolute value of TMAD (r=-0.61, P < 0.05), between GLS and percentage of TMAD (r=-0.64, P < 0.05). Patients with poor outcome (n = 6) had a lower longitudinal strain (LS) in the apical 2-chamber (A2C) views (-14.5 ± 4.6% vs -10.8 ± 1.3%, P = 0.007) but no statistical difference between A3C and A4C views. The ROC analysis demonstrated a cut­off value -11.8% for A2C-LS to predict adverse events (AUC 0.81, P = 0.027, 95% CI 0.632-0.993), with an 83.3% sensitivity and 81.2% specificity, followed by 3D LVEF (AUC = 0.29), absolute and percentage of TMAD (AUC = 0. 21, 0.23) as less sensitive predictors of poor postoperative outcome. Conclusion Direct effects of myocardial deformation related to revascularization can be characterized by STE during CABG surgery. GLS could be a more sensitive parameter in the perioperative environment, which correlates well with LV global function assessed by 3D LVEF and TMAD. Early impairment of anterior and inferior wall myocardial strain after CABG may contribute to short-term adverse clinical outcome. Abstract P206 Figure.


2019 ◽  
Vol 27 (18) ◽  
pp. 2006-2015
Author(s):  
Naoko Sawada ◽  
Koki Nakanishi ◽  
Masao Daimon ◽  
Yuriko Yoshida ◽  
Jumpei Ishiwata ◽  
...  

Aims Obesity carries significant risk for unfavorable ventricular remodeling and subsequent heart failure (HF) development, although the association between abdominal fat distribution and subclinical ventricular dysfunction is unclear. This study aimed to compare the subcutaneous and visceral abdominal adiposity with the risk of decreased ventricular strain. Methods We included 340 participants without overt cardiac disease who underwent laboratory testing, abdominal computed tomographic examination, and speckle-tracking echocardiography. Abdominal adiposity was quantitatively assessed as visceral fat area (VFA) and subcutaneous fat area (SFA) at the level of the umbilicus. Speckle-tracking echocardiography was performed to assess left ventricular global longitudinal strain (LVGLS) and right ventricular free-wall longitudinal strain (RVLS). Results Mean age was 56 ± 9 years, and 244 of the participants (72%) were male. The mean LVGLS and RVLS were −19.1 ± 3.0% and −25.0 ± 4.1%, respectively. Both VFA and SFA correlated with LVGLS ( r = 0.46 and r = 0.15, both p < 0.01) and RVLS ( r = 0.38 and r = 0.12, both p < 0.05), demonstrating a stronger correlation between VFA and ventricular strain. Multivariable analysis showed that VFA was significantly associated with LVGLS and RVLS, independent of traditional cardiovascular risk factors as well as pertinent laboratory and echocardiographic parameters (both p < 0.05), whereas SFA was not. Serum adiponectin level was correlated with LVGLS ( r = –0.34, p < 0.001) and RVLS ( r = –0.25, p < 0.001), although it lost statistical significance following multivariable adjustment. Conclusion In a sample of the general population, VFA, but not SFA, accumulation was significantly associated with decreased LV and RV strain, an association that may be involved in the increased risk of HF in obese individuals.


2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
A Buonauro ◽  
R Sorrentino ◽  
A Canora ◽  
M L Bocchino ◽  
R Esposito ◽  
...  

Abstract Background Pulmonary fibrosis (PF) is a heterogeneous group of diffuse parenchymal lung diseases, including idiopathic PF (IPF), which is the most frequent type in adults, and non-IPF. The impairment of right ventricular (RV) myocardial function of PF patients is not fully elucidated. Purpose To identify RV alterations in patients with interstitial PF and to evaluate possible differences between IPF and non-IPF by a combined assessment with standard and advanced echocardiography. Methods We enrolled 61 patients affected by interstitial PF (F/M: 16/45; age 67.9±8.1 years). 33 patients had IPF fibrosis and 28 non-IPF (bronchiolitis obliterans-organizing pneumonia and nonspecific interstitial pneumonia/fibrosis). Patients with coronary artery disease, overt heart failure, primary cardiomyopathies, other forms of diffuse parenchymal lung disease, history of pulmonary embolism and primary pulmonary hypertension were excluded. PF diagnosis was made by chest radiography, spirometry and chest high-resolution computed tomography. Lung cumulative damage was evaluated by diffusion capacity of the lung for carbon monoxide (DLco). Anthropometric parameters and blood pressure (BP) were recorded. All patients underwent a complete standard and advanced echo-Doppler exam including assessment of RV structure and function. RV global longitudinal strain (RVGLS), septal and lateral longitudinal strain (SLS and LLS respectively), were estimated by speckle tracking echocardiography (all strains were reported in absolute values). Results No significant difference was found in sex prevalence, systolic and diastolic BP and heart rate between the two groups, whereas IPF patients were older (65.2±8.1 vs. 70.1±7.6 years, p<0.01) than non-IPF. There was no difference in DLco between IPF and non-IPF patients. The two groups had similar left ventricular (LV) mass index, LV E/A ratio and E/e' ratio, and LV ejection fraction. RV diameters, tricuspid annulus plane systolic excursion (TAPSE) and pulmonary systolic artery pressure (PAPs) were not significantly different between the two groups, whereas IPF patients had lower RV GLS (20.2±3.1 vs. 23.0±3.6%, p=0.006), SLS (17.4±3.4 vs. 20.5±4.7%, p<0.01) and LLS (22.6±4.5 vs. 25.8±4.7%, p<0.02) compared to non-IPF patients. In the pooled population, DLco was related to RV GLS (r=0.51, p=0.004) and SLS (r=0.47, p<0.01), but not with age (p=0.121), TAPSE (p=0.532), and PAPs (p=0.875). In separate sub-analyses according to PF type, DLco was related to RVGLS in patients with IPF (r=0.52, p=0.03), but not in patients with non-IPF (r=0.41, p=0.16). Conclusion In patients with PF, RV systolic myocardial dysfunction is detectable by speckle tracking but not with standard echocardiography. In patients with IPF, RV dysfunction is associated with the degree of lung disease damage, as assessed by DLco.


2022 ◽  
Vol 12 ◽  
Author(s):  
Huiyun Chen ◽  
Yu Gong ◽  
Fangcan Sun ◽  
Bing Han ◽  
Bingyuan Zhou ◽  
...  

Objective: This study aimed to quantitatively assess myocardial strain in preterm children aged 5 to 8 years of pregnancy complicated by severe preeclampsia (PE) by two-dimensional (2D) speckle tracking echocardiography.Method: A cohort study of 23 preterm children delivered by severe PE pregnant women from 2010 to 2012 in the First Affiliated Hospital of Soochow University was carried out. 23 preterm children from uneventful pregnancies in the same period served as controls. Myocardial functions including left ventricular longitudinal strain, radial strain, circumferential strain, and right ventricular longitudinal strain were evaluated by conventional Doppler, tissue Doppler imaging, and 2D speckle-tracking echocardiography (2D STE). All examinations were performed by an experienced ultrasonographer using the VIVID E9 (GE Healthcare) machine, according to standard techniques.Results: Children aged 5–8 years delivered from severe PE presented less weight (24.41 vs. 20.89 kg, P &lt; 0.05), shorter height (124.1 vs 115.6 cm, P &lt; 0.05) and faster heart rates (84 vs. 93 bpm, P &lt; 0.05) compared to offspring of normotensive women. There were no significant differences in global left ventricular longitudinal strain, radial strain, circumferential strain, and right ventricular longitudinal strain between the children in the experimental group and the control group (P &gt; 0.05).Conclusion: Exposure to the intrauterine environment of severe PE during the fetal period did not have a significant impact on cardiac structure in premature children at 5–8 years old, but they had a higher resting heart rate which may be associated with cardiovascular disease in the long run.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
S.C Butcher ◽  
F Fortuni ◽  
J.M Montero ◽  
N Ajmone Marsan ◽  
V Delgado ◽  
...  

Abstract Background Right ventricular myocardial work (RVMW) is a novel method of non-invasively quantifying right ventricular (RV) systolic function. Through the use of speckle tracking echocardiography-derived RV pressure-strain loops, RVMW provides a quantitative evaluation of afterload-dependent RV systolic function. Purpose To investigate RVMW in patients with heart failure and reduced ejection fraction (HFrEF) and compare to that of patients without cardiovascular disease (CVD) and a structurally and functionally normal heart. Methods Noninvasive analysis of RVMW was performed in 23 HFrEF patients and 23 patients without cardiovascular or structural heart disease. The novel indices of RV global constructive work (RVGCW), RV global work index (RVGWI), RV wasted work (RVWW) and RV global work efficiency (RVGWE) were analysed utilizing proprietary software originally developed for the assessment of left ventricular myocardial work by speckle tracking echocardiography. Parameters of RVMW were then compared between the two patient groups. Results The HFrEF group had lower left ventricular (LV) ejection fraction (18.7% [±6.7] vs 60.1% [±4.6], p&lt;0.0001), LV global longitudinal strain (−3.6% [±1.6] vs −20.4% [±2.1), p&lt;0.0001) and RV global longitudinal strain (−10.0% [±4.2] vs −22.0% [±3.1], p&lt;0.0001) when compared to those with no CVD. Estimated pulmonary artery systolic pressure (42.5mm Hg [±12] vs 22.5mm Hg [±3.7], p&lt;0.0001) and estimated right atrial pressure (8mm Hg (5 to 15) vs 5mm Hg (5 to 5), p&lt;0.0001) were significantly higher in the HFrEF group. RVGWI (259.7mmHg% [±135.0] vs 385.3mmHg% [±103.1], p=0.001), RVGWW (83.7mmHg% [±58.6] vs 14.5mmHg% [8.5 to 20.5], p&lt;0.0001) and RVGWE (77.2% [11.4] vs 95.5% [93.5 to 97], p&lt;0.0001) were significantly lower in the HFrEF group when compared to those without CVD. There was no statistically significant difference in RVGCW between the two groups (353.5mmHg% [±118.4] vs 417.2 [±102.1], p=0.057). Conclusion The novel parameters of RVGWI, RVGWW and RVGWE were significantly reduced in patients with HFrEF when compared to those without CVD. Further exploration of the clinical role and prognostic value of these afterload dependent parameters of RV systolic function is warranted. Funding Acknowledgement Type of funding source: None


Author(s):  
Utku Pamuk ◽  
Hazım Gursu ◽  
Emine Azak ◽  
İlker Çetin

Objectives: This study aims to evaluate the role of speckle tracking echocardiography (STE) to identify myocardial deformation abnormalities in acute rheumatic fever. Methods: Twenty-seven patients and twenty-seven healthy children were studied prospectively. The patients were divided into two subgroups as moderate/severe carditis and mild/no carditis according to valve involvement. The left ventricular global longitudinal strain (LVGLS) and strain rate (LVGLSR), left ventricular global circumferential strain (LVGCS) and strain rate (LVGCSR), and right ventricular global longitudinal strain (RVGLS) and strain rate (RVGLSR) were examined by STE. Results: Left ventricular global longitudinal strain, LVGLSR, LVGCS, LVGCSR, RVGLS and RVGLSR were significantly lower in patients in acute phase of disease than controls. There were no differences in strain and strain rates between patient subgroups before treatment. After acute phase, statistically significant improvements were found in LVGLS, LVGLSR, LVGCSR values of the patients with moderate/severe carditis and LVGLS, LVGCS, LVGCSR, RVGLS, RVGLSR values of the patients with mild/no carditis. The strain parameters of the patients and controls did not differ significantly after the treatment. Conclusions: In acute phase of rheumatic heart disease, patients have reduced left and right ventricular strain and strain rates, which shows improvements after treatment.


Sign in / Sign up

Export Citation Format

Share Document