scholarly journals Recent Advances inAstragalus membranaceusAnti-Diabetic Research: Pharmacological Effects of Its Phytochemical Constituents

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Kojo Agyemang ◽  
Lifeng Han ◽  
Erwei Liu ◽  
Yi Zhang ◽  
Tao Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Disease Burden ◽  
Chemical Constituents ◽  
Pharmacological Action ◽  
Astragalus Membranaceus ◽  
Pharmacological Effects ◽  
Chinese Herbal ◽  
Recent Advances ◽  
The World ◽  
Phytochemical Constituents

The disease burden of diabetes mellitus is increasing throughout the world. The need for more potent drugs to complement the present anti-diabetic drugs has become an imperative.Astragalus membranaceus, a key component of most Chinese herbal anti-diabetic formulas, has been an important prospect for lead anti-diabetic compounds. It has been progressively studied for its anti-diabetic properties. Ethnopharmacological studies have established its potential to alleviate diabetes mellitus. Recent studies have sought to relate its chemical constituents to types 1 and 2 diabetes mellitus. Its total polysaccharides, saponins, and flavonoids fractions and several isolated compounds have been the most studied. The total polysaccharides fraction demonstrated activity to both types 1 and 2 diabetes mellitus. This paper discusses the anti-diabetic effects and pharmacological action of the chemical constituents in relation to types 1 and 2 diabetes mellitus.

scholarly journals A Review on the Cosmeceutical and External Applications ofNigella sativa

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Ahmad M. Eid ◽  
Nagib A. Elmarzugi ◽  
Laila M. Abu Ayyash ◽  
Maher N. Sawafta ◽  
Hadeel I. Daana
Keyword(s):  
Health Care ◽  
Wound Healing ◽  
Nigella Sativa ◽  
Chemical Constituents ◽  
Acne Vulgaris ◽  
World Health ◽  
Pharmacological Effects ◽  
The World ◽  
Wound Healing Effect ◽  
Health Organization

It is estimated by the World Health Organization (WHO) that most of the world’s population depends on herbal medicine for their health care.Nigella sativa (N. sativa),also known as black-caraway and as “Kalonji,” is a well-known seed all over the world. It is one of the most common medicinal plants worldwide and contains many useful chemical constituents that we can find in its fixed oil, such as thymoquinone, thymohydroquinone, dithymoquinone, thymol, nigellicine, carvacrol, nigellimine, nigellicine, nigellidine, and alpha-hederin. Due to these numerous important ingredients it was found that it affects different areas of our body and has many pharmacological effects as antibacterial, antiviral, anti-inflammatory, and wound healing effect and also for acne vulgaris, skin cancer, pigmentation, and many cosmeceutical applications. Based on the folklore usage ofN. sativaseeds and oil, they are used in various systems of food and medicines. The aim of this article is to provide a detailed survey of the literature of cosmeceutical and external applications ofN. sativawhich is expected to stimulate further studies on this subject.

Recent advances in biomaterials for the treatment of diabetic foot ulcers

2017 ◽  
Vol 5 (10) ◽  
pp. 1962-1975 ◽  
Author(s):  
Lisa N. Kasiewicz ◽  
Kathryn A. Whitehead
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
World Today ◽  
Recent Advances ◽  
The World

Diabetes mellitus is one of the most challenging epidemics facing the world today, with over 300 million patients affected worldwide.

scholarly journals A DETAILED OVERVIEW OF MEDICINAL PLANTS HAVING HYPOGLYCEMIC ACTIVITY

2016 ◽  
Vol 8 (2) ◽  
pp. 139 ◽  
Author(s):  
Sandra Celine ◽  
Shawn Tomy ◽  
Ujwala TK ◽  
Sam Johnson Udaya Chander
Keyword(s):  
Diabetes Mellitus ◽  
Herbal Medicine ◽  
Chemical Constituents ◽  
Herbal Medicines ◽  
Developed Countries ◽  
Cerebrovascular Diseases ◽  
World Health ◽  
The World ◽  
After Cancer ◽  
Health Organization

Diabetes mellitus represents a spectrum of metabolic disorder, which has become one of the major public health concerns worldwide. Diabetes mellitus has emerged as a third leading killer after cancer and cardiovascular/cerebrovascular diseases and India has a distinction of having largest number of diabetics in world second to China. Herbal medicine for treating chronic diseases, especially diabetes has gained an exponential growth in the last few years and both developing and developed countries are adopting herbal drugs for treatment of diabetes mellitus. The World Health Organization (WHO) has listed 21,000 plants, which are used for medicinal purposes around the world. The WHO has defined herbal medicines as finished labelled medicinal products that contain aerial or underground parts of the plants or other plant material or combination thereof as active ingredients, whether in crude state or as plant preparations. This review attempts to present the profiles of plants with hypoglycemic properties, reported in the literature with proper categorization according to the botanical name, family, parts used, chemical constituents, and its other uses. Relevant medical databases and websites were searched. To qualify for inclusion, the herbs should have confirmed hypoglycemic potential. Other criteria for inclusion are: published in English and peer-reviewed journals. We also used related keywords like diabetes mellitus, plant, herb, glycemic control, natural or herbal medicine, Ayurvedic plants, and hypoglycemic plants, as keywords or combination of them. A total of 151 herbs belonging to 72 families were outlined in this review.

scholarly journals Phytochemical, Therapeutic, and Ethnopharmacological Overview for a Traditionally Important Herb:Boerhavia diffusaLinn.

2014 ◽  
Vol 2014 ◽  
pp. 1-19 ◽  
Author(s):  
Shikha Mishra ◽  
Vidhu Aeri ◽  
Praveen Kumar Gaur ◽  
Sanjay M. Jachak
Keyword(s):  
Chemical Analysis ◽  
Disease Burden ◽  
Therapeutic Potential ◽  
Chemical Constituents ◽  
Urinary System ◽  
Pharmacological Activities ◽  
The World ◽  
Therapeutic Properties ◽  
Therapeutic Activities ◽  
Boerhavia Diffusa

Boerhavia diffusa(BD) is a plant ofrasayanacategory as per ayurvedic claims. It is reported to possess antiaging, disease prevention, and life strengthening activities which hold enormous influence in disease burden and affordability/availability of healthcare in the world.Objective.This paper has been compiled to comment on the studies reported for BD to highlight its chemical and therapeutic potential along with its ethnopharmacological considerations.Methods.In the present paper, a detailed account of chemical constituents and pharmacological activities has been presented. All the findings were correlated with modern pharmacological activities to appraise the value of BD.Results.Chemical analysis of BD gives a wide variety of chemical constituents, namely, rotenoids, flavonoids, xanthones, purine nucleoside, lignans, and steroids. Various ethnopharmacological reports emphasize its role in disorders of reproductive system, gastrointestinal system, respiratory system, urinary system, hepatic system/jaundice, cardiovascular system, and cancer.Conclusions.The studies on the therapeutic activities of BD range from studies on crude extracts to isolated compounds; however some of the studies require sophistication and validated results. BD is a plant of enormous importance in the purview of its chemical and therapeutic properties.

scholarly journals Recent Progress on Chemical Constituents and Pharmacological Effects of the Genus Nigella

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Yun Niu ◽  
Li Zhou ◽  
Lijun Meng ◽  
Sitan Chen ◽  
Changyang Ma ◽  
...  
Keyword(s):  
Recent Progress ◽  
Seed Oil ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Seed Extract ◽  
Chemical Component ◽  
Pharmacological Effects ◽  
Bioactive Constituents ◽  
The World ◽  
Hepatoprotective Effects

Seeds of the genus Nigella plants as folk medicine are often used to prevent and treat asthma, diarrhea, dyslipidemia, and other diseases around the world. Pharmacological researches showed that seed extract and seed oil have antibacterial, antioxidant, hypoglycemic, and hepatoprotective effects which attributed to their bioactive constituents such as alkaloids, saponins, flavones, and phenols. This paper has covered recent progresses on chemical and pharmacological researches on these plants, including their compounds and pharmacological effects. It was found that the chemical component researches were focused on the seed oil. Therefore, more attention should be paid to the profile of the whole constituents in the seeds.

Ultrastructure of neuromuscular relationships in the canine heartworm (dirofilaria immitis)

1986 ◽  
Vol 44 ◽  
pp. 278-279
Author(s):  
W. L. Steffens ◽  
Nancy B. Roberts ◽  
J. M. Bowen
Keyword(s):  
Dirofilaria Immitis ◽  
Domestic Dogs ◽  
Structural Description ◽  
Pharmacological Effects ◽  
Free Living ◽  
Canine Heartworm ◽  
The World ◽  
Synaptic Region ◽  
Muscle Innervation ◽  
Insight Into

The canine heartworm is a common and serious nematode parasite of domestic dogs in many parts of the world. Although nematode neuroanatomy is fairly well documented, the emphasis has been on sensory anatomy and primarily in free-living soil species and ascarids. Lee and Miller reported on the muscular anatomy in the heartworm, but provided little insight into the peripheral nervous system or myoneural relationships. The classical fine-structural description of nematode muscle innervation is Rosenbluth's earlier work in Ascaris. Since the pharmacological effects of some nematacides currently being developed are neuromuscular in nature, a better understanding of heartworm myoneural anatomy, particularly in reference to the synaptic region is warranted.

Pharmacognostical and pharmacological activity of Justicia gendarussa burm.f.: a comprehensive review

2020 ◽  
Vol 11 (3) ◽  
pp. 3384-3390
Author(s):  
Ashish ◽  
Anjali ◽  
Dixit Praveen K ◽  
Nagarajan K ◽  
Sahoo Jagannath
Keyword(s):  
Pharmacological Activity ◽  
Chemical Constituents ◽  
Biological Action ◽  
Andaman Islands ◽  
Comprehensive Review ◽  
Medicinal Value ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Pharmacologically Active ◽  
Different Parts

Justicia gendarussa Burm .f. (family Acanthaceae) which is also known as willow-leaves and commonly known as Nili-Nirgundi, it is very commonly found nearby to China and its availability is very common in larger parts of India and Andaman islands. Traditionally it is used to treat various sorts of disorders such as wound healing, anti-inflammatory, anti-oxidant, antiproliferative, anti-arthritic etc. Justicia gendarussa is one of the crucial herbs which has been used in the Ayurveda. Majorly leaves parts of the plant shows the pharmacological activity but the root of the plant Justicia gendarussa is also have the important medicinal values. A large variety of pharmacologically active constituents i.e., alkaloids, flavonoids, saponin, carbohydrates, steroids, triterpenoids, carotenoids, aminoacids, tannins, phenolics, coumarines and anthaquinones are also present in this plant and they makes the plant pharmacologically important. The activity of the plant is also dependent on the solvent which is used for the extraction the various vital chemical constituents. The different- different parts of the plants having the different medicinal values also differ in the chemical values. This review is not only focused on the essential phytochemical constituents which is available in the plant but it also explains their necessary medicinal value to shows the essential biological action and phytopharmacological actions of various parts of the plant.

Association and treatment of diabetes in patients affected by Covid-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1198-1201
Author(s):  
Syed Yasir Afaque
Keyword(s):  
Diabetes Mellitus ◽  
Prognostic Value ◽  
Heart Diseases ◽  
The Novel ◽  
The World ◽  
Treatment Of Diabetes ◽  
Coronavirus Infection ◽  
Composite Outcomes ◽  
Novel Coronavirus ◽  
The Impact

In December 2019, a unique coronavirus infection, SARS-CoV-2, was first identified in the province of Wuhan in China. Since then, it spread rapidly all over the world and has been responsible for a large number of morbidity and mortality among humans. According to a latest study, Diabetes mellitus, heart diseases, Hypertension etc. are being considered important risk factors for the development of this infection and is also associated with unfavorable outcomes in these patients. There is little evidence concerning the trail back of these patients possibly because of a small number of participants and people who experienced primary composite outcomes (such as admission in the ICU, usage of machine-driven ventilation or even fatality of these patients). Until now, there are no academic findings that have proven independent prognostic value of diabetes on death in the novel Coronavirus patients. However, there are several conjectures linking Diabetes with the impact as well as progression of COVID-19 in these patients. The aim of this review is to acknowledge about the association amongst Diabetes and the novel Coronavirus and the result of the infection in such patients.

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