scholarly journals Recent Progress on Chemical Constituents and Pharmacological Effects of the Genus Nigella

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Yun Niu ◽  
Li Zhou ◽  
Lijun Meng ◽  
Sitan Chen ◽  
Changyang Ma ◽  
...  
Keyword(s):  
Recent Progress ◽  
Seed Oil ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Seed Extract ◽  
Chemical Component ◽  
Pharmacological Effects ◽  
Bioactive Constituents ◽  
The World ◽  
Hepatoprotective Effects

Seeds of the genus Nigella plants as folk medicine are often used to prevent and treat asthma, diarrhea, dyslipidemia, and other diseases around the world. Pharmacological researches showed that seed extract and seed oil have antibacterial, antioxidant, hypoglycemic, and hepatoprotective effects which attributed to their bioactive constituents such as alkaloids, saponins, flavones, and phenols. This paper has covered recent progresses on chemical and pharmacological researches on these plants, including their compounds and pharmacological effects. It was found that the chemical component researches were focused on the seed oil. Therefore, more attention should be paid to the profile of the whole constituents in the seeds.

scholarly journals Ballota nigra L. – an overview of pharmacological effects and traditional uses

2020 ◽  
Vol 66 (3) ◽  
pp. 56-65
Author(s):  
Filip Przerwa ◽  
Arnold Kukowka ◽  
Izabela Uzar
Keyword(s):  
Wound Healing ◽  
Folk Medicine ◽  
Cancer Drug ◽  
Pharmacological Effects ◽  
13Th Century ◽  
Traditional Uses ◽  
Wide Range ◽  
The World ◽  
Upset Stomach ◽  
Potential Cancer

Abstract Ballota nigra, also known as black horehound is a common medical herb used in folk medicine around the world. First reported mentions of its medical properties and use goes as far as the 13th century. The use of black horehound depends on regions and countries. It is used mostly to treat e.g. mild sleep disorders, nervousness, upset stomach, wound healing. It can be used as an anti-inflammatory, antibacterial, antiprotozoal, antifungal drug. Moreover, it has been reported as a potential cancer drug. This extensive usage is particularly interesting for us. The aim of this review is to present available data on B. nigra pharmacological effects and known traditional uses gathered from a wide range of scientific articles published in 1997–2020.

scholarly journals CHEMICAL CONSTITUENTS AND PHARMACOLOGICAL EFFECTS OF LEPIDIUM SATIVUM-A REVIEW

2019 ◽  
pp. 1-10 ◽  
Author(s):  
ALI ESMAIL AL-SNAFI
Keyword(s):  
Amino Acids ◽  
Uric Acid ◽  
Chemical Constituents ◽  
Sinapic Acid ◽  
Lepidium Sativum ◽  
Protective Effects ◽  
Pharmacological Effects ◽  
Bioactive Constituents ◽  
Volatile Oils ◽  
Current Review

Lepidium sativum contained many bioactive constituents included cardiac glycoside, alkaloids, phenolic, flavonoids, cardiotonic glycosides, coumarins, glucosinolates, carbohydrates, proteins and amino-acids, mucilage, resins, saponins, sterols, tannins, volatile oils, triterpene, sinapic acid and uric acid. The pharmacological investigation revealed that Lepidium sativum possessed antimicrobial, antidiabetic, antioxidant, anticancer, reproductive, gastrointestinal, respiratory, anti-inflammatory, analgesic, antipyretic, cardiovascular, hypolipidemic, diuretic, central nervous, fracture healing and protective effects. The current review discussed the chemical constituents and pharmacological effects of Lepidium sativum.

scholarly journals A Review on the Cosmeceutical and External Applications ofNigella sativa

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Ahmad M. Eid ◽  
Nagib A. Elmarzugi ◽  
Laila M. Abu Ayyash ◽  
Maher N. Sawafta ◽  
Hadeel I. Daana
Keyword(s):  
Health Care ◽  
Wound Healing ◽  
Nigella Sativa ◽  
Chemical Constituents ◽  
Acne Vulgaris ◽  
World Health ◽  
Pharmacological Effects ◽  
The World ◽  
Wound Healing Effect ◽  
Health Organization

It is estimated by the World Health Organization (WHO) that most of the world’s population depends on herbal medicine for their health care.Nigella sativa (N. sativa),also known as black-caraway and as “Kalonji,” is a well-known seed all over the world. It is one of the most common medicinal plants worldwide and contains many useful chemical constituents that we can find in its fixed oil, such as thymoquinone, thymohydroquinone, dithymoquinone, thymol, nigellicine, carvacrol, nigellimine, nigellicine, nigellidine, and alpha-hederin. Due to these numerous important ingredients it was found that it affects different areas of our body and has many pharmacological effects as antibacterial, antiviral, anti-inflammatory, and wound healing effect and also for acne vulgaris, skin cancer, pigmentation, and many cosmeceutical applications. Based on the folklore usage ofN. sativaseeds and oil, they are used in various systems of food and medicines. The aim of this article is to provide a detailed survey of the literature of cosmeceutical and external applications ofN. sativawhich is expected to stimulate further studies on this subject.

scholarly journals A Review of the Pharmacological Effects of the Dried Root ofPolygonum cuspidatum(Hu Zhang) and Its Constituents

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Huan Zhang ◽  
Chang Li ◽  
Sin-Tung Kwok ◽  
Qing-Wen Zhang ◽  
Shun-Wan Chan
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Folk Medicine ◽  
Therapeutic Effects ◽  
Pharmacological Effects ◽  
Polygonum Cuspidatum ◽  
Republic Of China ◽  
Therapeutic Uses ◽  
Snake Bites ◽  
The World

Traditional Chinese medicine (TCM) has been widely used in China for thousands of years to treat and prevent diseases. TCM has been proven safe and effective, and it is being considered as one of the important types of complementary and alternative medicine and receives increasing attention worldwide. The dried root ofPolygonum cuspidatumSieb. et Zucc. (also known as “Hu Zhang” in Chinese) is one of the medicinal herbs listed in the Pharmacopoeia of the People's Republic of China. Hu Zhang is widely distributed in the world. It can be found in Asia and North America and is used as folk medicine in countries such as Japan and Korea. In China, Hu Zhang is usually used in combination with other TCM herbs. The therapeutic uses of those Hu Zhang-containing TCM prescriptions or formulations are for treating cough, hepatitis, jaundice, amenorrhea, leucorrhea, arthralgia, burns and snake bites. Recent pharmacological and clinical studies have indicated that Hu Zhang has antiviral, antimicrobial, anti-inflammatory, neuroprotective, and cardioprotective functions. This review gives a summary of the reported therapeutic effects of the active compounds and the different extracts of Hu Zhang.

scholarly journals Red Raspberry (Rubus idaeus L.) Seed Oil: A Review

Plants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 944
Author(s):  
Audronė Ispiryan ◽  
Jonas Viškelis ◽  
Pranas Viškelis
Keyword(s):  
Fatty Acids ◽  
Seed Oil ◽  
Therapeutic Potential ◽  
Chemical Constituents ◽  
Research Literature ◽  
Rubus Idaeus ◽  
Pharmacological Effects ◽  
Practical Application ◽  
Red Raspberry ◽  
Recent Developments

Raspberry (Rubus idaeus L.) seed oil (RSO) is considered as a source of high value bioactive compounds as fatty acids, tocopherols, tocotrienols, carotenoids, flavonoids, phytosterols, antioxidants, monoterpenes and many other chemical constituents. These compounds are appreciated as a source of nutrition for humans, as additives in cosmetic production, has immense therapeutic potential. Raspberry seed oil exerts many pharmacological effects included antimicrobial, antioxidant, anti-inflammatory activity and many other effects. The various databases like PubMed and Science Direct were used to identify, analyze and summarize the research literature on raspberries. This review will highlight recent developments of the chemical constituents and nutraceutical and cosmetical effects of RSO. Practical application: analyzed recent researches and international patents containing raspberry seed oil can help practitioners of various industries create new high-value products.

scholarly journals Recent Advances inAstragalus membranaceusAnti-Diabetic Research: Pharmacological Effects of Its Phytochemical Constituents

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Kojo Agyemang ◽  
Lifeng Han ◽  
Erwei Liu ◽  
Yi Zhang ◽  
Tao Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Disease Burden ◽  
Chemical Constituents ◽  
Pharmacological Action ◽  
Astragalus Membranaceus ◽  
Pharmacological Effects ◽  
Chinese Herbal ◽  
Recent Advances ◽  
The World ◽  
Phytochemical Constituents

The disease burden of diabetes mellitus is increasing throughout the world. The need for more potent drugs to complement the present anti-diabetic drugs has become an imperative.Astragalus membranaceus, a key component of most Chinese herbal anti-diabetic formulas, has been an important prospect for lead anti-diabetic compounds. It has been progressively studied for its anti-diabetic properties. Ethnopharmacological studies have established its potential to alleviate diabetes mellitus. Recent studies have sought to relate its chemical constituents to types 1 and 2 diabetes mellitus. Its total polysaccharides, saponins, and flavonoids fractions and several isolated compounds have been the most studied. The total polysaccharides fraction demonstrated activity to both types 1 and 2 diabetes mellitus. This paper discusses the anti-diabetic effects and pharmacological action of the chemical constituents in relation to types 1 and 2 diabetes mellitus.

scholarly journals A comprehensive review on the pharmacological properties of Diplazium esculentum, an edible fern

2020 ◽  
Vol 3 (1) ◽  
pp. 01-09
Author(s):  
Tapas Chaudhuri
Keyword(s):  
Chemical Constituents ◽  
Folk Medicine ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Wide Range ◽  
Structural Formulas ◽  
The World ◽  
Ethnomedicinal Plant ◽  
Young Leaves ◽  
Ethnomedicinal Uses

Diplazium esculentum (Family: Athyriaceae), one of the most popular wild edible fern, is considered as a pharmacologically diverse ethnomedicinal plant. The coiled fronds and young leaves of this plant have a wide range ethnomedicinal uses in folk medicine around the world directed for a number of ailments. The present article is the first comprehensive review on the pharmacological activities of this particular edible fern. The structural formulas of all the chemical constituents identified and isolated so far from D. esculentum are also provided in the present review. The most thoroughly studied pharmacological activities viz., antioxidant, antimicrobial, immunomodulatory, neuromodulatory, anti-fertility, cytotoxic, etc.) of the D. esculentum extracts have been discussed. This comprehensive review will be of help for the future researchers investigating for more potent compounds and their pharmacological activities.

Pharmacognostic and analytical assessment for Pterolobium hexapetalum (Roth.) Santapau and Wagh. – A dynamic Folklore therapeutic plant

2020 ◽  
Vol 11 (3) ◽  
pp. 3338-3348
Author(s):  
Sharmila S ◽  
Dhivya S M ◽  
Akilandeswari D ◽  
Mownika S ◽  
Ramya E K
Keyword(s):  
Chemical Constituents ◽  
Folk Medicine ◽  
Fluorescence Analysis ◽  
Healthy Plant ◽  
Phytochemical Analysis ◽  
Bioactive Constituents ◽  
Plant Materials ◽  
Chemical Reagents ◽  
Analytical Assessment ◽  
Study Species

The aim of the current study was to assess a scrupulous pharmacognostic cram is to enhance the constructive information with regard to its species identification, characterization and standardization of a dynamic folklore therapeutic plant Pterolobium hexapetalum. It is one of the largest scrambling shrubs belonging to the Leguminosae family having significant medicinal properties. The aerial part of the fresh and healthy plant materials was collected from the Maruthamalai hill, Coimbatore District with a strong traditional background. The confined name of the species is “Karuindu” used as medicine in Siddha, Ayurveda and folk medicine for treating various illnesses. The external morphology of study species, the anatomy of leaf and stem, physicochemical examination of plant powder, powder with diverse chemical reagents, fluorescence analysis of therapeutic powder, ash values, mineral studies, heavy metal analysis, extractive values, phytochemical analysis, GCMS analytical studies were examined with the aim of drafting pharmacopeial principles. The studied plant contains 19 bioactive chemical constituents which confirm the healing domination. The analytical assessment of study species authenticates the presence of various bioactive constituents with a broad range of remedial properties which is used to treat manifold muddle as well it provides a comprehensive insight regarding the phytoconstituents profile which could be browbeaten for the maturity of plant-supported drugs.

scholarly journals Chemical constituents of Aglaia odorata and Aglaia hoaensis

2021 ◽  
Vol 5 (3) ◽  
pp. first
Author(s):  
Lien Hoa Dieu Nguyen ◽  
Hào Chí Lê ◽  
Thy Ngoc Diem Nguyen ◽  
Ly Thi Thao Nguyen ◽  
Le Thu Thi Nguyen ◽  
...  
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Research Work ◽  
Octadecenoic Acid ◽  
2D Nmr ◽  
Chemical Structures ◽  
The World ◽  
First Time ◽  
Whole Tree

Aglaia is the largest genus of the Meliaceae family with about 120 species, which grow mainly in the tropical and subtropical regions. In Vietnam, the genus contains about 30 species. Many are used in folk medicine for the treatment of different diseases. Rocaglamides, bisamides, lignans, triterpenoids and steroids are the main classes of compounds found in the genus. Some of them exhibit diverse biological activities. This research work reports the isolation of four compounds from A. odorata and A. hoaensis. Extraction was carried out using Soxhlet extractors with organic solvents followed by concentration of the solvents to yield crude extracts. Isolation was performed using column chromatography on silica gel and gel permeation on Sephadex LH-20. Chemical structures were determined using 1D NMR (1H, 13C NMR, DEPT), 2D NMR (HSQC, HMBC, COSY, NOESY), IR and HRESIMS spectroscopic methods, and comparison of the spectral data with those in literature. Two triterpenoids, aglaiadoratol and 3b -friedelinol, were isolated from the whole tree of A. odorata. Two other compounds, (+)-syringaresinol lignan and threo-9,10-O-isopropylidene- 13-hydroxy-(11E)-octadecenoic acid, a derivative of fatty acid, were obtained from the bark of A. hoaensis. Among the four isolated compounds, this is the first time that aglaiadoratol has been reported in the world. In addition, (+)-syringares inol ligan and threo-9,10-O-isopropylidene-13- hydroxy-(11E)-octadecenoic acid are reported here for the first time in A. hoaensis.

Ultrastructure of neuromuscular relationships in the canine heartworm (dirofilaria immitis)

1986 ◽  
Vol 44 ◽  
pp. 278-279
Author(s):  
W. L. Steffens ◽  
Nancy B. Roberts ◽  
J. M. Bowen
Keyword(s):  
Dirofilaria Immitis ◽  
Domestic Dogs ◽  
Structural Description ◽  
Pharmacological Effects ◽  
Free Living ◽  
Canine Heartworm ◽  
The World ◽  
Synaptic Region ◽  
Muscle Innervation ◽  
Insight Into

The canine heartworm is a common and serious nematode parasite of domestic dogs in many parts of the world. Although nematode neuroanatomy is fairly well documented, the emphasis has been on sensory anatomy and primarily in free-living soil species and ascarids. Lee and Miller reported on the muscular anatomy in the heartworm, but provided little insight into the peripheral nervous system or myoneural relationships. The classical fine-structural description of nematode muscle innervation is Rosenbluth's earlier work in Ascaris. Since the pharmacological effects of some nematacides currently being developed are neuromuscular in nature, a better understanding of heartworm myoneural anatomy, particularly in reference to the synaptic region is warranted.

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