Pharmacognostical and pharmacological activity of Justicia gendarussa burm.f.: a comprehensive review

2020 ◽  
Vol 11 (3) ◽  
pp. 3384-3390
Author(s):  
Ashish ◽  
Anjali ◽  
Dixit Praveen K ◽  
Nagarajan K ◽  
Sahoo Jagannath
Keyword(s):  
Pharmacological Activity ◽  
Chemical Constituents ◽  
Biological Action ◽  
Andaman Islands ◽  
Comprehensive Review ◽  
Medicinal Value ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Pharmacologically Active ◽  
Different Parts

Justicia gendarussa Burm .f. (family Acanthaceae) which is also known as willow-leaves and commonly known as Nili-Nirgundi, it is very commonly found nearby to China and its availability is very common in larger parts of India and Andaman islands. Traditionally it is used to treat various sorts of disorders such as wound healing, anti-inflammatory, anti-oxidant, antiproliferative, anti-arthritic etc. Justicia gendarussa is one of the crucial herbs which has been used in the Ayurveda. Majorly leaves parts of the plant shows the pharmacological activity but the root of the plant Justicia gendarussa is also have the important medicinal values. A large variety of pharmacologically active constituents i.e., alkaloids, flavonoids, saponin, carbohydrates, steroids, triterpenoids, carotenoids, aminoacids, tannins, phenolics, coumarines and anthaquinones are also present in this plant and they makes the plant pharmacologically important. The activity of the plant is also dependent on the solvent which is used for the extraction the various vital chemical constituents. The different- different parts of the plants having the different medicinal values also differ in the chemical values. This review is not only focused on the essential phytochemical constituents which is available in the plant but it also explains their necessary medicinal value to shows the essential biological action and phytopharmacological actions of various parts of the plant.

Gas Chromatography Mass Spectrometry Application to Investigate of Phytonutrient Different Parts of Lotus

2021 ◽  
pp. 35-40
Author(s):  
Warachate Khobjai ◽  
◽  
Khemjira Jarmkom ◽  
Nakuntwalai Wisidsri ◽  
Surachai Techaoei
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Chemical Constituents ◽  
Gas Chromatography Mass Spectrometry ◽  
Plant Foods ◽  
Chromatography Mass Spectrometry ◽  
Phytochemical Constituents ◽  
Major Chemical ◽  
Mass Spectrometry Application ◽  
Different Parts

Phytonutrients, also called phytochemicals, are chemicals produced by plants. Foods and vegetables with phytonutrients have antioxidant and anti-inflammatory benefits. The aim of this study was to analyzed 4 parts of 3 lotuses phytochemical constituents by using gas chromatography mass spectrometry. Our results showed that different parts of lotus had a different chemical compound. The major chemical constituents in each extract are 6-Methoxy-2-[p-tolyl]cinchoninic acid (23.92%), Stigmastan-3, 5-diene (6.17%), 5(1H)-Azulenone, 2, 4, 6, 7, 8, 8a-hexahydro-3, 8-dimethyl-4-(1-methylethylidene)-, (8S-cis)- (24.44%), 2-Cyclohexane-1-carboxaldehyde, 2, 6-dimethyl-6-(4-methyl-3-pentennyl (18.15%), Stigmastan-3, 5-diene (24.04%), 2(1H)Naphthalenone, 3, 5, 6, 7, 8, 8a-hexanhydro-4, 8a-dimethyl-6-(1-methylethenyl)-(6.49%), 2-[p-Methoxyphenyl]-8-methylcinchoninic acid (12.98%), Ergosta-4, 6, 22-trien-3, beta, -ol (13.57%), and Stigmastan-3, 5-diene (26.05%). Therefore, Phytonutrients could also provide significant benefits for human’s health that eat plant foods.

Pharmacological Importance of Saraca asoca: A Review

2021 ◽  
pp. 131-135
Author(s):  
Chandrakant P. Rathod ◽  
Mahavir H. Ghante
Keyword(s):  
Pharmacological Activity ◽  
Medium Size ◽  
Saraca Asoca ◽  
Cns Depressant ◽  
Evergreen Tree ◽  
Medicinal Value ◽  
Anti Cancer ◽  
Indigenous Plant ◽  
Anti Oxidant

Ayurveda is a traditional medicinal system which has been used consistently. Asoka is one of India's most holy and legendary trees. Ashoka, also known as Saraca asoca (Roxb.) Wilde, is an indigenous plant that belongs to the Caesalpiniaceae subfamily of the Legume. It is an evergreen tree of medium size. The objective of this review is to provide detailed description of botany, phytochemicals, medicinal value and pharmacological activity. Saraca asoca was reported to be comprising phytoconstituents, such as Flavonoids, Steroids, Glycosides, Saponins, Carbohydrates, Proteins as well as many Pharmacologic activities such as anti-diabetic, CNS depressant, anti-helminthic, cardio protective, anti-bacterial, anti-menorrhagic, anti-hyperglycaemic and anti-oxidant activities, anti-cancer activities.

A COMPREHENSIVE REVIEW OF PHYTOCHEMICAL AND PHARMACOLOGICAL OVERVIEW ON CELOSIA CRISTATA FOR FUTURE PROSPECTIVE RESEARCH

2020 ◽  
pp. 21-24
Author(s):  
MAHAVEER SING ◽  
SRAVAN KUMAR P ◽  
BIRENDRA SHRIVASTAVA ◽  
PAMULA REDDY B
Keyword(s):  
Traditional Medicine ◽  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Wide Range ◽  
Celosia Cristata ◽  
Prospective Research ◽  
Different Parts

Celosia cristata (CC) is used in traditional medicine to cure several disorders. It is a member of the genus Celosia and is commonly known as cockscomb, since the flower looks like the head on a rooster. Many sensitive ingredients were isolated from different parts of the plant. The recent studies showed that the plant exerted a wide range of pharmacological activities. The chemical constituents and pharmacological activities of CC were presented in this review.

scholarly journals Preliminary Phytochemical Appraisal of Selected Medicinal Plants

2021 ◽  
Vol 11 (2-S) ◽  
pp. 56-58
Author(s):  
E Mohan ◽  
S Suriya ◽  
S Shanmugam ◽  
CP Muthupandi ◽  
K Rajendran
Keyword(s):  
Chemical Constituents ◽  
Petroleum Ether Extract ◽  
Acetone Extract ◽  
Acorus Calamus ◽  
Ether Extract ◽  
Solanum Torvum ◽  
Plant Parts ◽  
Phytochemical Constituents ◽  
Pharmacologically Active ◽  
Senna Alata

Preliminary phytochemical tests played a significant role in finding and locating chemical constituents which are source of pharmacologically active principles. By consider the medicinal importance of tuber of Acorus calamus, flower of Senna alata and fruit of Solanum torvum, the present study was designed to screen the phytochemical constituents present in such plant parts preliminarily. The phytochemical analyses were conducted by employing standard methods to detect the presence/absence of alkaloids, carbohydrates, flavonoids, glycosides, phenols, phytosterols, proteins, saponins and tannins. The results of present study revealed that alkaloids were found to be present in all the three plants analyzed and all the three solvents extracted, whereas, glycosides and phenols were absent. The acetone extract of Acorus calamus and Solanum torvum showed the presence more number of phytochemicals (4 each) and petroleum ether extract of Senna alata and Solanum torvum revealed the presence of only one compound. The potential active principles of the detected compounds should be quantified and pharmacologically evaluated. Keywords: Preliminary phytochemical analyses, Acorus calamus tuber, Senna alata flower, Solanum torvum fruit.

scholarly journals Trado-Medical uses, Chemical Constituents and Biological Activities of Newbouldia laevis (Bignoniaceae): A Review

2021 ◽  
Author(s):  
Innocent U Okagu ◽  
Joseph C Ndefo ◽  
Matthias Onyebuchi Agbo
Keyword(s):  
Skin Diseases ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Male Reproduction ◽  
Flowering Plant ◽  
Scientific Investigations ◽  
Health Promoting ◽  
Phytochemical Constituents ◽  
Ethnobotanical Uses ◽  
Different Parts

Newbouldia laevis (P. Beauv.) Seem. (Family, Bignoniaceae), commonly known as tree of life, is a purple-flowering plant that is widely distributed in many parts of Africa. Different parts of the plant, including the leaves, flower, stems and roots are prevalently used in African traditional medicine for the management of many diseases and conditions like diabetes, hypertension, skin diseases, ulcer, tumors, pains, infectious diseases, inflammation, dysentery, sickle cell disease and impotency. This review discusses the trado-medical uses, chemical constituents, and biological activities of N. laevis. Based on information generated from scientific investigations deposited in PubMed and SCOPUS, the chemical constituents of the plant include glycosides, anthraquinolones, volatile oils, tannins, steroids, alkaloids, flavonoids, terpenoids and sterols. Extracts different parts of the plant and compounds isolated from them have been reported to have several health-promoting potentials such as antioxidant, antimalarial, trypanocidal, antimicrobial, anthelmintic, analgesic, anti-inflammatory, antidiabetic, anti-arthritic, anti-thrombotic, cytoprotective, anti-hypertensive, central nervous system modulatory, male reproduction enhancing and oxytocic properties. These scientific investigations have led credence to the ethnobotanical uses of the plant in folkloric practice. In addition, the presence of phytochemical constituents in the plant might be responsible for the wide biological potentials.

scholarly journals Evaluation of the Phytochemical Constituents of Extracts of Kigelia africana Fruit and Sorghum bicolor, Stalk in Lagos Nigeria

2021 ◽  
pp. 49-58
Author(s):  
Nkem F. Obianagha ◽  
Chukwuma J. Okafor ◽  
Ufuoma Chukwuani ◽  
Omobolanle Abioye Ogundahunsi ◽  
Steve O. Ogbonnia ◽  
...  
Keyword(s):  
Sorghum Bicolor ◽  
Chemical Constituents ◽  
Herbal Medicines ◽  
Acid Methyl Ester ◽  
Biological Action ◽  
Mass Spectrometry Analysis ◽  
Gas Chromatography Mass Spectrometry ◽  
Indigenous Plants ◽  
Spectrometry Analysis ◽  
Phytochemical Constituents

The use of herbal medicines and phytonutrients or nutraceuticals with numerous secondary metabolites continues to expand rapidly across the world, with many people now resorting to these products to treat various health challenges in different national healthcare settings. Therefore, the study is aimed at evaluating the phytochemical composition in the fruit extract of Kigelia africana and Sorghum bicolor stalks bought from the Mushin market in Lagos, Nigeria to ascertain its numerous pharmacological activities and identify the various chemical compounds responsible for these activities. Ethanol extracts of identified fresh fruits of K. africana  and S. bicolor stalks (L) were prepared for phytochemical screening using established methods for Alkaloids, Tannins, Phenols, Flavonoids, and Terpenoids testing as well as Gas Chromatography-Mass Spectrometry Analysis (GC-MS) for the analysis of the extracts. The chemical constituents present in both extracts were tannins, phenols, flavonoids, and saponins as well as alkaloids found only in K. africana. Also, the chromatogram of K. africana revealed the presence of forty-four (44) phytochemical constituents. At the same time, that of S. bicolor were twenty-nine (29) phytochemical constituents that could contribute to the medicinal quality of the plant with 9, 12-Octadeadienoic acid (Z, Z), and 13-Docosenoic acid, methyl ester, (Z) found as the major compounds respectively. The K africana and S. bicolor African indigenous plants in Lagos, Nigeria, possess different phytocomponents of scientific importance, biological action, and potential medicinal properties. There is a need for more standardization and purification of this herbal formulation for the treatment of diseases.

scholarly journals Isolation, Structural Characterization and Identification of Major Constituents in Ephedra foliata Naturally Growing in Iraq by TLC, GC-MS and UPLC-ESI-MS/MS

2020 ◽  
Vol 29 (2) ◽  
pp. 48-61
Author(s):  
Ahmed S. Khaleefa ◽  
Maha N. Hamad
Keyword(s):  
Aerial Part ◽  
Chemical Constituents ◽  
Antitumor Action ◽  
Esi Ms ◽  
Medicinal Value ◽  
Antifungal Effects ◽  
Immunosuppressive Action ◽  
Phytochemical Constituents ◽  
Ephedra Foliata ◽  
Antibacterial And Antifungal

Abstract:    The aerial part of Ephedra foliata Family Ephedraceae have long been used in traditional medicine and now Ephedra species have medicinal, ecological, and commercial value. The variety of pharmacological actions of this plant is due to its chemical constituents. Ephedrine and related alkaloids; are the newly potential medicinal value of Ephedra supplements for weight loss or performance improvement. Other pharmacological actions like antibacterial and antifungal effects of the phenolic acid compounds, the immunosuppressive action of the polysaccharides, and the antitumor action of flavonoids. The genus of this plant wildly distributed throughout asia, america, europe, and north africa.  Aim of study:  this study is to screen the phytochemical constituents due to the importance of pharmacological actions of this plant. Methods:  the aerial part of E. foliata was macerated in 80% ethanol for 9 days and fractionated by n-hexane, chloroform, ethyl acetate, and n-butanol. The n-hexane, chloroform, n-butanol fractions, and isolated compounds were analyzed by GC-MS, TLC, UPLC ESI MS/MS. Results and discussion: The various chromatographic and spectroscopic results indicate  the presence of a different type of phytochemicals like ephedrine, 6hka, vicenin 2 and quercetin 3-sophoroside-7-rhamnoside.

In-vivo evaluation of lipid lowering ability of Chloris paraguaiensis extracts

2020 ◽  
Vol 7 (2) ◽  
pp. 21-24
Author(s):  
Pavani C H
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
The Body ◽  
Lipid Lowering ◽  
Medical Systems ◽  
In Vivo Evaluation ◽  
Standard Drug ◽  
Anti Oxidant ◽  
And Control

Hyperlipidemia is the immediate results of the excessive fat intake in food. This results in the elevated levels of cholesterol and triglycerides in the blood. This leads to heart conditions like CAD, hypertension, congestive heart failure as risk factors which can be lethal. There are many drugs to treat and control the lipids levels in the body. These drugs are either designed to prevent LDL accumulation and VLDL synthesis. Some drugs also lower the elevated levels of saturated lipids in the body. But many drugs are known to cause side effects and adverse effects; therefore, alternatives to the drugs are the subjects for current investigations. Herbs and medicinal plants are used as treatment sources for many years. They have been used in the Indian medical systems like Ayurveda, Siddha etc. As the application of herbs in the treatment is growing, there is an urgent need for the establishment of Pharmacological reasoning and standardization of the activity of the medicinal plants. Chloris paraguaiensis Steud. is Poyaceae member that is called locally as Uppugaddi. Traditionally it is used to treat Rheumatism, Diabetes, fever and diarrhoea. The chemical constituents are known to have anti-oxidant properties and most of the anti-oxidants have anti-hyperlipidemic activity too. Since the plant has abundant flavonoid and phenol content, the current research focusses on the investigation of the anti-hyperlipidemic activity of the plant Chloris extracts. Extracts of Chloris at 200mg/kg showed a comparably similar anti hyperlipidemia activity to that of the standard drug. The extracts showed a dose based increase in the activity at 100 and 200mg/kg body weight.

Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review

2020 ◽  
Vol 23 ◽  
Author(s):  
Roohi Mohi-ud-din ◽  
Reyaz Hassan Mir ◽  
Prince Ahad Mir ◽  
Saeema Farooq ◽  
Syed Naiem Raza ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Use ◽  
Comprehensive Review ◽  
Wide Range ◽  
Anti Cancer ◽  
Comprehensive Survey ◽  
Ethnomedicinal Uses

Background: Genus Berberis (family Berberidaceae), which contains about 650 species and 17 genera worldwide, has been used in folklore and various traditional medicine systems. Berberis Linn. is the most established group among genera with around 450-500 species across the world. This comprehensive review will not only help researchers for further evaluation but also provide substantial information for future exploitation of species to develop novel herbal formulations. Objective: The present review is focussed to summarize and collect the updated review of information of Genus Berberis species reported to date regarding their ethnomedicinal information, chemical constituents, traditional/folklore use, and reported pharmacological activities on more than 40 species of Berberis. Conclusion: A comprehensive survey of the literature reveals that various species of the genus possess various phytoconstituents mainly alkaloids, flavonoid based compounds isolated from different parts of a plant with a wide range of pharmacological activities. So far, many pharmacological activities like anti-cancer, anti-hyperlipidemic, hepatoprotective, immunomodulatory, anti-inflammatory both in vitro & in vivo and clinical study of different extracts/isolated compounds of different species of Berberis have been reported, proving their importance as a medicinal plant and claiming their traditional use.

Phytochemistry, Traditional Uses and Pharmacological properties of Enhydra fluctuans Lour: A Comprehensive Review.

2020 ◽  
Vol 21 ◽  
Author(s):  
Antica Barua ◽  
Muhammad Shaiful Alam ◽  
Md. Junaid ◽  
Yeasmin Akter ◽  
Syeda Samira Afrose ◽  
...  
Keyword(s):  
Sesquiterpene Lactone ◽  
Chemical Constituents ◽  
Phytochemical Analysis ◽  
Microbial Infection ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Cns Depressant ◽  
Isoflavone Glycoside ◽  
Online Library ◽  
Pharmacologically Active

Background: Enhydra fluctuans Lour, a tropical herb, commonly known as helencha or harkuch, belonging to family Asteraceae, and is an edible semi-aquatic herbaceous vegetable plant with serrate leaves, grows commonly in different parts of the world. Enhydra fluctuans possesses potential pharmacological role against inflammation, cancer, diarrhea, microbial infection, diabetes, and so on. Aim of the review: This review aims to provide the most current information on the botanical characterization, distribution, traditional uses, chemical constituents, as well as the pharmacological activities of Enhydra fluctuans Lour. Materials and methods: The recently updated information on Enhydra fluctuans was gathered from scientific journals, books, and worldwide accepted scientific databases via a library and electronic search (PubMed, Elsevier, Google Scholar, Springer, Scopus, Web of Science, Wiley online library. All of the full-text articles and abstracts related to Enhydra were screened. The most important and relevant articles were carefully chosen for study in this review. Results: Crude extracts and isolated compounds of Enhydra fluctuans Lour has been reported pharmacologically active against cytoprotective, analgesic and anti-inflammatory, antimicrobial, anticancer, anti-diarrhoeal, antihelmintic, CNS depressant, hepatoprotective, thrombolytic, antidiabetic, anti-oxidant, phagocytic and cytotoxic, and neuroprotective potential activities. Discussion: Phytochemical analysis from different studies has reported Germacranolide, Sesquiterpene lactone, Flavonoid, Essential oil, Steroid, Diterpenoid, Melampolide, Sesquiterpene lactone, Isoflavone glycoside as major compounds of Enhydra fluctuans Lour. Conclusions: However, more research is important to explore the mode of action of bioactive components of the plant and its therapeutic capabilities.

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