Multifocal Adult Rhabdomyoma of the Head and Neck Manifestation in 7 Locations and Review of the Literature

Background. Adult rhabdomyoma is a rare benign tumour with the differentiation of striated muscle tissue, which mainly occurs in the head and neck region. Twenty-six cases of multifocal adult rhabdomyoma are documented in the literature.Method. We report a 55-year-old male with simultaneous diagnosis of 7 adult rhabdomyomas and review the literature of multifocal adult rhabdomyoma.Result. Review of the literature revealed 26 cases of multifocal adult rhabdomyoma, of which only 7 presented with more than 2 lesions. Mean age at diagnosis was 65 years with a male to female ratio of 5.5 : 1. Common localizations were the parapharyngeal space (36%), larynx (15%), submandibular (14%), paratracheal region (12%), tongue (11%), and floor of mouth (9%). Besides the known radiological features of adult rhabdomyoma, our case showed FDG-uptake in (18) F-FDG PET/CT.Conclusion. This is the first case of multifocal adult rhabdomyoma published, with as many as 7 simultaneous adult rhabdomyomas of the head and neck.

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A convolutional neural network-based system to detect malignant findings in FDG PET/CT examinations

10.21203/rs.2.13839/v1 ◽

2019 ◽

Author(s):

Keisuke Kawauchi ◽

Sho Furuya ◽

Kenji Hirata ◽

Chietsugu Katoh ◽

Osamu Manabe ◽

...

Keyword(s):

Neural Network ◽

Convolutional Neural Network ◽

Head And Neck ◽

Fdg Pet ◽

Imaging Modality ◽

Neck Region ◽

Whole Body ◽

Pet Ct ◽

Medicine Physician ◽

Fdg Pet Ct

Abstract Background As the number of PET/CT scanners increases and FDG PET/CT becomes a common imaging modality for oncology, the demands for automated detection systems on artificial intelligence (AI) to prevent human oversight and misdiagnosis are rapidly growing. We aimed to develop a convolutional neural network (CNN)-based system that can classify whole-body FDG PET as 1) benign, 2) malignant, or 3) equivocal.Methods This retrospective study investigated 3,485 sequential patients with malignant or suspected malignant disease, who underwent whole-body FDG PET/CT at our institute. All the cases were classified into the 3 categories by a nuclear medicine physician. A residual network (ResNet)-based CNN architecture was built for classifying patients into the 3 categories. This network was trained with PET images. Five-fold cross-validations were carried out to estimate the classification performance. In addition, we examined whether the CNN could determine the location of the malignant uptake, be it in the head-and-neck region, chest, abdomen, or pelvic region.Results There were 1,280 (37%), 1,450 (42%) and 755 (22%) patients classified as benign, malignant and equivocal, respectively. In patient-based analysis, the CNN predicted benign and malignant images with 99.4% and 99.4% accuracy, respectively. Furthermore, in region-based analysis, the prediction was correct with the probability of 97.3% (head-and-neck), 96.6% (chest), 92.8% (abdomen) and 99.6% (pelvic region), respectively.Conclusion The CNN-based system reliably classified FDG PET images into 3 categories, indicating that it would be helpful for physicians as a double-checking system to prevent oversight and misdiagnosis.

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Clinicopathological Profile of Rhabdomyosarcoma in Children

Journal of Bangladesh College of Physicians and Surgeons ◽

10.3329/jbcps.v30i3.12461 ◽

2012 ◽

Vol 30 (3) ◽

pp. 132-136

Author(s):

Umme Habiba Begum ◽

Afiqul Islam

Keyword(s):

Head And Neck ◽

Neck Region ◽

Mass Lesion ◽

Female Ratio ◽

Head And Neck Region ◽

Clinicopathological Profile ◽

Common Clinical Presentation ◽

The Common ◽

Medical University ◽

Male To Female

Objectives: To describe the clinical profile as well as histopathological sub-types of Rhabdomyosarcoma in children.Methods: A hospital base prospective observational study was conducted among 20 diagnosed cases of Rhabdomyosarcoma in children, those attending in Hemato-Oncology department of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka in the period between January to December 2009.Results: The peak incidence of Rhabdomyosarcoma was in 1-5 years of age group (n=9, 45%) with mean age 6.83 years with male to female ratio 5.66:1. The common sites of primary tumor was in head and neck region (40%, n=08), followed by genito-urinary tract, 30% (n=06), extremities 20% (n=04), trunk 10% (n=02). The most common clinical presentation was mass lesion 100% (n=20), followed by local pain 25% (n=05), urinary obstructions 15% (n=03) dysphagia, chronic otorrhea, dysuria, haematuria, and proptoses were 10% each (n=02, each); The histological sub-types were Embryonal 60% (n=12), alveolar 30% (n=6), and Botryoid 10% (n=02); Of Embryonal variety in head and neck region 58.33% (n=7), and Genito-urinary sites 41.67% (n=5); of Alveolar variety in trunk 66.67% (n=4), and in extremities33.33% (n=2), of Botryoid sub-type frequency was equal in head - neck region and genitourinary site 50% each (n=1).Conclusion: Children with Rhabdomyosarcoma presented mostly in 1 to 5 years of age, with mass lesion (100%), predominantly in head and neck region (40%) and the commonest histological sub-type was Embryonal variety (60%). DOI: http://dx.doi.org/10.3329/jbcps.v30i3.12461 J Bangladesh Coll Phys Surg 2012; 30: 132-136

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Extra-renal malignant rhabdoid tumor of head and neck region: Characteristics of tracer uptake on FDG PET/CT in tumor with rare histology

Indian Journal of Nuclear Medicine ◽

10.4103/0972-3919.136605 ◽

2014 ◽

Vol 29 (3) ◽

pp. 197

Author(s):

Venkatesh Rangarajan ◽

AmeyaD Puranik ◽

Nilendu Purandare ◽

Mukta Ramadwar ◽

Archi Agrawal ◽

...

Keyword(s):

Head And Neck ◽

Fdg Pet ◽

Neck Region ◽

Tracer Uptake ◽

Rhabdoid Tumor ◽

Malignant Rhabdoid Tumor ◽

Head And Neck Region ◽

Pet Ct ◽

Fdg Pet Ct

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Combined modality therapy for naso-oropharyngeal solitary extramedullary plasmacytoma: case report

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20174342 ◽

2017 ◽

Vol 3 (4) ◽

pp. 1105

Author(s):

Andrea Masarykova ◽

Marin Dzongov ◽

Alexandra Hanicova ◽

Ingrid Zavacka ◽

Danijela Scepanovic

Keyword(s):

Case Report ◽

Head And Neck ◽

Plasma Cell ◽

Fdg Pet ◽

Neck Region ◽

Extramedullary Plasmacytoma ◽

Head And Neck Region ◽

Pet Ct ◽

Fdg Pet Ct ◽

Solitary Extramedullary Plasmacytoma

<p>Most patients with plasma cell neoplasia have generalized disease at diagnosis. However, some patients have a solitary extramedullary plasmacytomas (SEPs). SEPs are rare, typically solitary tumors comprising approximately 3–5% all plasma cell neoplasms. Almost 90% arise in the head and neck region, especially in the nasal cavity, sinuses, oropharynx, salivary glands and larynx. Solitary extramedullary plasmacytoma (SEP) has a predilection for the male gender and occurs most frequently in patients 50 years and older. SEP often runs an indolent clinical course with a tendency for local recurrence, and progresses to plasma cell myeloma in about 15% of patients. In this paper, we have reported the case of SEP of the naso-oropharynx in 55 years old woman who was presented with a sense of the nasal obstruction. The resection was performed and a mature plasmacytoma was demonstrated histologically. However, ENT examination and positron emission tomography/computed tomography examination with 18-fluorodeoxyglucose (18-FDG PET/CT) have shown that the patient had residual naso-oropharyngeal disease after surgery. A negative bone marrow biopsy and 18-FDG PET/CT have confirmed that it was a solitary extramedullary plasmacytoma of the head and neck region. Following the surgery, intensity modulated radiotherapy (IMRT) was administered. No relapse or progression to the multiple myeloma was recorded during the 3.5 years of follow-up. This case report, which describes a rare tumor of the naso-oropharynx, is expected to improve the recognition and referral of this condition in medical practice. </p>

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