scholarly journals Low-Grade Central Osteosarcoma of the Rib: A Case Report and Brief Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Mana Moghadamfalahi ◽  
Houda Alatassi

Low-grade central osteosarcoma is a rare variant of osteosarcoma which comprises less than 1-2% of all osteosarcomas. Most low-grade osteosarcomas involve long bones, most commonly distal femur, and proximal tibia. Histologically this tumor is difficult to diagnose, and an unusual location makes this diagnosis even more challenging. Here we report a case of low-grade osteosarcoma presenting as a chest wall mass involving the left 6th–8th ribs. This unusual site of presentation significantly added to the diagnostic difficulties of this rare tumor with challenging histologic features. To the best of our knowledge, only six cases of low-grade central osteosarcoma of the ribs have been reported in the English literature.

2002 ◽  
Vol 126 (8) ◽  
pp. 975-978 ◽  
Author(s):  
Subodh M. Lele ◽  
Satish Chundru ◽  
Gregory Chaljub ◽  
Patrick Adegboyega ◽  
Abida K. Haque

Abstract Hibernomas are rare neoplasms composed of brown adipose tissue. The behavior of these neoplasms has been described as uniformly benign in humans. The only recurrence cited in the English literature involved a sarcoma with hibernoma-like features, which was reported in abstract form. We present 2 cases of hibernoma, one that continued to grow following partial excision and another at an unusual site (anterior abdominal wall). Both of these tumors overexpressed p53 protein by immunohistochemistry, which was a novel finding. A review of the literature highlights recent advances that may help confirm the diagnosis and explain the biology of these rare tumors.


2019 ◽  
Vol 143 (12) ◽  
pp. 1472-1476 ◽  
Author(s):  
Saul Suster

Context.— Follicular nodules are the most common source of diagnostic difficulties in the practice of surgical pathology of the thyroid. This is due to a variety of factors, the most salient of which is the lack of well-defined criteria and evidence-based data for the diagnosis of these lesions. Objectives.— To discuss some of the assumptions that have been accrued over the years regarding the criteria by which we evaluate such lesions. Data Sources.— The information presented herein is based on review of the literature and the author's personal experience. Conclusions.— Thyroid nodules with a predominant follicular growth pattern span the range from benign lesions (hyperplastic nodules, adenomatoid nodules, follicular adenomas) to malignant neoplasms (follicular carcinoma, follicular variant of papillary carcinoma) with a host of intermediate or indeterminate lesions found in between. Advances in immunohistochemistry and molecular pathology have not yet provided a reliable way of separating the borderline or intermediate cases. Low-grade and intermediate or borderline follicular-patterned thyroid lesions are those most often prone to difficulties for interpretation. Newer and potential future approaches for the evaluation of these lesions are discussed.


2020 ◽  
Vol 81 (06) ◽  
pp. 565-570
Author(s):  
Alok Mohan Uppar ◽  
Shilpa Rao ◽  
Chandrajit Prasad ◽  
Arivazhagan Arimappamagan ◽  
Vani Santosh

AbstractGreater superficial petrosal nerve (GSPN) schwannoma is a rare clinical entity. It forms a small subset of the larger group of facial nerve schwannomas. A thorough literature search yielded only 27 such cases reported to date in the English literature. We present one such rare case of GSPN schwannoma and discuss the clinical spectrum and management along with a review of the literature. We demonstrate the surgical steps in an operative video.


2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Qiao Wang ◽  
Xia Zhao ◽  
Ping Han

Extrauterine endometrial stromal sarcoma (ESS) arising in endometriosis is extremely rare, particularly in the colorectum. It should always be included in the differential diagnosis of primary tumors originating from gastrointestinal tract in females, given that preoperative endoscopical biopsy may reveal no specific changes. We reported a case of ESS arising in colorectal endometriosis and reviewed the previous 7 cases reported in the English literature. Our patient, who was unavailable for tumor resection and refused further adjuvant therapy, played a role in representing the natural history of low-grade extragenital ESS. This case was the only death from ESS arising in colorectal endometriosis.


Rare Tumors ◽  
2018 ◽  
Vol 10 ◽  
pp. 203636131877703 ◽  
Author(s):  
Bita Geramizadeh ◽  
Zahra Zare ◽  
Amir Reza Dehghanian ◽  
Shahram Bolandparvaz ◽  
Mahsa Marzban

Low-grade fibromyxoid sarcoma is a rare soft tissue tumor which has been mostly reported in lower extremities; however, it can also occur in other parts of the body such as head and neck and abdominal wall, but its occurrence in the abdominal cavity and mesentery of bowel is an extremely rare event and has very rarely been reported. Herein, we report our experience with a 24-year-old lady with a huge mesenteric mass, turned out to be low-grade fibromyxoid sarcoma. This case is the largest one reported in the English literature. We will also discuss about the previously reported cases of low-grade fibromyxoid sarcoma in the English literature.


1994 ◽  
Vol 12 (5) ◽  
pp. 747-749 ◽  
Author(s):  
Moises Kaweblum ◽  
Maria Del Carmen Aguilar ◽  
Eduardo Blancas ◽  
Jaime Kaweblum ◽  
Wallace B. Lehman ◽  
...  

2021 ◽  
pp. 983-988
Author(s):  
Daniel Cirotski ◽  
Jyoti Panicker

Osteosarcoma is the most common primary bone cancer in all age groups. Metastasis mostly occurs with high-grade tumors disseminating to the lungs and other bones. Spread to the pancreas is rare and undocumented in the low-grade subtypes. Additionally, it is uncommon for the disease course of low-grade subtypes to involve multiple relapses. We present a 35-year-old woman with parosteal osteosarcoma who has experienced an atypical metastasis to the pancreas as well as multiple local and pulmonary relapses. The lesion was identified incidentally on routine imaging, and the patient underwent resection. We compare our case to the other reports of pancreatic metastasis in the literature. Despite being especially rare, clinicians ought to be aware of pancreatic metastasis of osteosarcoma. Furthermore, despite parosteal osteosarcoma’s less aggressive disease course, it can uncommonly lead to multiple relapses. We present a rare case exemplifying these phenomena in the prognostically favorable histologic subtype of parosteal osteosarcoma.


2021 ◽  
Vol 64 ◽  
pp. 101725
Author(s):  
Danny Lascano ◽  
Michael J. Zobel ◽  
Abigail K. Zamora ◽  
Murad Alturkustani ◽  
Shengmei Zhou ◽  
...  

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