scholarly journals Automated Detection and Evaluation of Swallowing Using a Combined EMG/Bioimpedance Measurement System

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Corinna Schultheiss ◽  
Thomas Schauer ◽  
Holger Nahrstaedt ◽  
Rainer O. Seidl
Keyword(s):  
Measurement System ◽  
Healthy Subjects ◽  
Measurement Procedure ◽  
Automated Detection ◽  
Swallowing Disorders ◽  
Head Movements ◽  
Swallowing Disorder ◽  
Two Stage ◽  
Bioimpedance Measurement ◽  
Control Study

Introduction. Developing an automated diagnostic and therapeutic instrument for treating swallowing disorders requires procedures able to reliably detect and evaluate a swallow. We tested a two-stage detection procedure based on a combined electromyography/bioimpedance (EMBI) measurement system. EMBI is able to detect swallows and distinguish them from similar movements in healthy test subjects.Study Design. The study was planned and conducted as a case-control study (EA 1/019/10, and EA1/160/09, EA1/161/09).Method. The study looked at differences in swallowing parameters in general and in the event of penetration during swallows in healthy subjects and in patients with an oropharyngeal swallowing disorder. A two-stage automated swallow detection procedure which used electromyography (EMG) and bioimpedance (BI) to reliably detect swallows was developed.Results. Statistically significant differences between healthy subjects and patients with a swallowing disorder were found in swallowing parameters previously used to distinguish between swallowing and head movements. Our two-stage algorithm was able to reliably detect swallows (sensitivity = 96.1%, specificity = 97.1%) on the basis of these differences.Discussion. Using a two-stage detection procedure, the EMBI measurement procedure is able to detect and evaluate swallows automatically and reliably. The two procedures (EMBI + swallow detection) could in future form the basis for automated diagnosis and treatment (stimulation) of swallowing disorders.

Association of Serum Homocysteine Level and Interstitial Lung Disease in Systemic Sclerosis: A Case-control Study

2018 ◽  
Vol 15 (1) ◽  
pp. 74-78
Author(s):  
Mohammadali Nazarinia ◽  
Asghar Zare ◽  
Mohammad javad Fallahi ◽  
Mesbah Shams
Keyword(s):  
Systemic Sclerosis ◽  
Healthy Subjects ◽  
Case Control Study ◽  
Homocysteine Level ◽  
Case Control ◽  
Control Group ◽  
Lung Involvement ◽  
Serum Homocysteine ◽  
The Mean ◽  
Control Study

Background:Systemic sclerosis is a disorder of connective tissue with unknown cause, affecting the skin and internal organs, characterized by fibrotic changes.Objective:To determine the correlation between serum homocysteine level and interstitial lung involvement in systemic sclerosis. </P><P> Materials and Methods: In this case – control study, 59 patients who fulfilled the ACR/EULAR classification criteria for systemic sclerosis and were referred to Hafez Hospital of Shiraz, Iran, were included as the case group. Fifty nine healthy subjects were involved as the control group. Patients were divided into two groups based on interstitial lung involvement and two subtypes, diffuse and limited type. Serum homocysteine, vitamin B12, and folate levels compared between the controls, and cases groups.Results:Of 59 case and control group, 53 (%89.8) were female and the mean age did not differ in both groups (P=0.929). Thirty five (%59.3) patients had interstitial lung involvement and 38(%64.4) had diffuse cutaneous systemic sclerosis. The mean serum homocysteine level was 13.9±6.3 µmol/L in the case and 13.7±9.2 µmol/L in the control group (P=0.86). The mean serum homocysteine level did not differ between the patients with and without interstitial lung involvement (P=0.52). The patients with lung involvement was older than those without lung involvement (P=0.004). Lung disease was more common in diffuse type (P=0.014).Conclusion:In our study, serum homocysteine level did not differ between the patients and healthy subjects. Also, there was no correlation between serum homocysteine level and lung involvement, but lung involvement was more common in older patients and also diffuse subtype.

scholarly journals A Two-Stage Matched Case–Control Study on Multiple Hypertensive Candidate Genes in Han Chinese

2012 ◽  
Vol 25 (7) ◽  
pp. 804-811 ◽  
Author(s):  
Tai-Yue Kuo ◽  
Mei-Jyh Kang ◽  
Jaw-Wen Chen ◽  
Hung-Yun Ho ◽  
Chih-Tai Ting ◽  
...  
Keyword(s):  
Candidate Genes ◽  
Case Control Study ◽  
Case Control ◽  
Han Chinese ◽  
Two Stage ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals Comparison Of Lung Function Tests Between Healthy And Asthmatic Individuals

BioSight ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 6-10
Author(s):  
Hira Liaquat ◽  
Tabinda Najeeb ◽  
Rahima Aftab ◽  
Tayyaba Kazmi ◽  
Padma Rathore ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Case Control Study ◽  
Pulmonary Function Tests ◽  
Case Control ◽  
Asthmatic Patients ◽  
Function Tests ◽  
Lower Lung ◽  
Medical University ◽  
Control Study ◽  
Asthmatic Case

Background: Comparison of pulmonary function tests (PFTs) were achieved between asthmatic case and Controls. Materials & Methods: Case-control study conducted at Baqai Medical University (50 cases and 50 control). PFTs in both the participants were estimated by spirometry; FEC, FEV1 and their ratios were estimated. Results: According to the findings all spirometric values were lower in asthmatic patients as compared to healthy subjects. Moreover the asthamatic subjects had lower lung values when compared with healthy subjects. Conclusion: The current study evaluated spirometric values in asthmatic patients in Gadap area. This study's findings can be applied to the treatment of asthma in people of all ages.

scholarly journals Joint Assessment of Equilibrium and Neuromotor Function: A Validation Study in Patients with Fibromyalgia

Diagnostics ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1057
Author(s):  
Rafael Lomas-Vega ◽  
Daniel Rodríguez-Almagro ◽  
Ana Belén Peinado-Rubia ◽  
Noelia Zagalaz-Anula ◽  
Francisco Molina ◽  
...  
Keyword(s):  
Validation Study ◽  
Concurrent Validity ◽  
Healthy Subjects ◽  
Screening Tool ◽  
Short Form ◽  
Fibromyalgia Impact Questionnaire ◽  
Head Movements ◽  
Nominal Group ◽  
Neuromotor Function ◽  
Joint Assessment

Objective: To develop and validate a tool for evaluating balance and neuromotor function in patients with fibromyalgia (FMS). Methods: Brainstorming, the nominal group technique, and pilot-testing were used to select a battery of 20 functional balance tests that were included in a screening tool. A total of 108 subjects (62 with fibromyalgia syndrome, 22 aged over 65 years, and 24 healthy subjects) participated in this validation study. Factor validity, internal consistency, the ability to discriminate between patients and healthy subjects, and concurrent validity with the Fibromyalgia Impact Questionnaire (FIQ), the Central Sensitization Inventory (CSI), the 12-Item Short-Form Health Survey (SF-12), and other tools for measuring balance, such as the Dizziness Handicap Inventory (DHI), the Activities-Specific Balance Confidence Scale (ABC-16), the Falls Efficacy Scale-International (FES-I), and posturographic parameters, were evaluated. Results: The factorial analysis extracted four factors that explained 70% of the variance. The Alpha Cronbach value was 0.928. Concurrent validity of the screening tool with respect to other tools was high, and the receiver operating characteristic (ROC) curve analysis showed an AUC value of 0.932 for discriminating between healthy and FMS subjects. Severe balance disorder related to head movements in FMS patients was found. Conclusion: The 20-item JAEN (Joint Assessment of Equilibrium and Neuro-motor Function) screening tool is a valid and reliable tool for assessing balance in patients with FMS.

scholarly journals Effect of levetiracetam drug on antioxidant and liver enzymes in epileptic patients: case-control study

2020 ◽  
Vol 20 (2) ◽  
pp. 984-990
Author(s):  
Atena Mahdavi ◽  
Amirmansour Alavi Naeini ◽  
Mohammadreza Najafi ◽  
Mohammadreza Maracy ◽  
Mohammadreza Aghaye Ghazvini
Keyword(s):  
Healthy Subjects ◽  
Case Control Study ◽  
Liver Enzymes ◽  
Case Control ◽  
Dietary Intakes ◽  
Dietary Antioxidant ◽  
Antioxidant Intake ◽  
Epileptic Patients ◽  
Total Antioxidant ◽  
Control Study

Background: There is a limited amount of data regarding levetiracetam (LEV), an antiepileptic drug. Objective: This study was conducted to assess the effect of LEV on antioxidant status and liver enzymes. Method: In this case-control study, 33 epileptic patients under treatment with LEV for at least 6 months were compared with 35 healthy subjects. We measured serum total antioxidant capacity (TAC), salivary superoxide dismutase (SOD), alanine aminoteransferase (ALT), and aspartate aminoteransferase (AST) levels in both groups. Dietary intakes were collected using a Food Frequency Questionnaire (FFQ). Result: The level of TAC in the healthy subjects was significantly higher than it was in the patients (P=0.02), but the mean of ALT (P=0.02) and AST (P=0.03) was significantly higher in the patients in comparison with the controls. Mean salivary SOD showed no difference between the two groups. In the patients, the duration of drug use was inversely correlated with serum TAC (p=0.04) and had a direct correlation with ALT (p=0.01) and AST (p=0.03.). Conclusion: The results of our study indicated that LEV increased liver enzymes Also, treatment with this drug did not improve oxidative stress, but this could be due to the different in the dietary antioxidant intake. Routine screening of the liver and antioxidant enzymes in patients with chronic use of LEV is recommended. Keywords: Levetiracetam; antioxidant; liver enzymes; epilepsy.

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