scholarly journals Numerical Modeling of Force-Stiffness Response of Cross-Linked Actin Networks Using Tensegrity Systems

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Xian Xu ◽  
Yafeng Wang ◽  
Yaozhi Luo

A three-dimensional tensegrity structure is used as a computational model for cross-linked actin networks. The postbuckling behavior of the members under compression is considered and the constitutive relation of the postbuckling members is modeled as a second-order polynomial. A numerical scheme incorporating the equivalent constitution of the postbuckling members is used to predict the structural response of the tensegrity model under compression loads. The numerical simulation shows that the stiffness of the tensegrity structure nonlinearly increases before member buckling and abruptly decreases to a lower level as soon as members buckle. This result qualitatively mimics the experimentally observed stiffness to compression stress response of cross-linked actin networks. In order to take member length variety into account, a large number of simulations with the length of buckling members varying in the given range are also carried out. It is found that the mean response of the simulations using different buckling member length exhibits more resemblance to the experimental observation.

GEODYNAMICS ◽  
2021 ◽  
Vol 2(31)2021 (2(31)) ◽  
pp. 29-40
Author(s):  
Mykhailo Fys ◽  
◽  
Andrii Brydun ◽  
Mariana Yurkiv ◽  
Andrii Sohor ◽  
...  

Purpose. To investigate the features of the algorithm implementation for finding the derivatives of the spatial distribution function of the planet's masses with the use of high-order Stokes constants and, on the basis of this, to find its analytical expression. According to the given methodology, to carry out calculations with the help of which to carry on the study of dynamic phenomena occurring inside an ellipsoidal planet. The proposed method involves the determination of the derivatives of the mass distribution function by the sum, the coefficients of which are obtained from the system of equations, which is incorrect. In order to solve it, an error-resistant method for calculating unknowns was used. The implementation of the construction is carried out in an iterative way, while for the initial approximation we take the three-dimensional function of the density of the Earth's masses, built according to Stokes constants up to the second order inclusive, by dynamic compression by the one-dimensional density distribution, and we determine the expansion coefficients of the derivatives of the function in the variables to the third order inclusive. They are followed by the corresponding density function, which is then taken as the initial one. The process is repeated until the specified order of approximation is reached. To obtain a stable result, we use the Cesaro summation method (method of means).. The calculations performed with the help of programs that implement the given algorithm, while the achieved high (ninth) order of obtaining the terms of the sum of calculations. The studies of the convergence of the sum of the series have been carried out, and on this basis, a conclusion has been made about the advisability of using the generalized finding of the sums based on the Cesaro method. The optimal number of contents of the sum terms has been chosen, provides convergence both for the mass distribution function and for its derivatives. Calculations of the deviations of mass distribution from the mean value ("inhomogeneities") for extreme points of the earth's geoid, which basically show the total compensation along the radius of the Earth, have been performed. For such three-dimensional distributions, calculations were performed and schematic maps were constructed according to the taken into account values of deviations of three-dimensional distributions of the mean ("inhomogeneities") at different depths reflecting the general structure of the Earth's internal structure. The presented vector diagrams of the horizontal components of the density gradient at characteristic depths (2891 km - core-mantle, 700 km - middle of the mantle, also the upper mantle - 200, 100 km) allow us to draw preliminary conclusions about the global movement of masses. At the same time, a closed loop is observed on the “core-mantle” edge, which is an analogy of a closed electric circuit. For shallower depths, differentiation of vector motions is already taking place, which gives hope for attracting these vector-grams to the study of dynamic motions inside the Earth. In fact, the vertical component (derivative with respect to the z variable) is directed towards the center of mass and confirms the main property of mass distributions - growth when approaching the center of mass. The method of stable solution of incorrect linear systems is applied, by means of which the vector-gram of the gradient of the mass distribution function is constructed. The nature of such schemes provides a tool for possible causes of mass redistribution in the middle of the planet and to identify possible factors of tectonic processes in the middle of the Earth, i.e indirectly confirms the gravitational convection of masses. The proposed technique can be used to create detailed models of density functions and its characteristics (derivatives) of the planet's interior, and the results of numerical experiments - to solve tectonics problems.


Author(s):  
Sevim Türktekin Çelikesir ◽  
Mehmet Akkurt ◽  
Aliasghar Jarrahpour ◽  
Habib Allah Shafie ◽  
Ömer Çelik

In the title compound, C15H11ClN2O4, the central β-lactam ring is approximately planar [maximum deviation = 0.044 (2) Å for the N atom from the mean plane] and subtends dihedral angles of 61.17 (11) and 40.21 (12) °, respectively, with the nitro and chlorobenzene rings. Both substituents lie to the same side of the β-lactam core. In the crystal, N—H...O hydrogen bonds link the molecules intoC(4) chains propagating in [010]. The chains are cross-linked by C—H...O and weak C—H...π interactions, generating a three-dimensional network. The solvent molecules were found to be highly disordered and their contribution to the scattering was removed with the SQUEEZE procedure inPLATON[Spek (2009).Acta Cryst.D65, 148–155], which indicated a solvent cavity of volume 318 Å3containing approximately 114 electrons. These solvent molecules are not considered in the given chemical formula and other crystal data.


2002 ◽  
Vol 727 ◽  
Author(s):  
S. Ichikawa ◽  
T. Akita ◽  
M. Okumura ◽  
M. Haruta ◽  
K. Tanaka

AbstractThe catalytic properties of nanostructured gold catalyst are known to depend on the size of the gold particles and to be activated when the size decreases to a few nanometers. We investigated the size dependence of the three-dimensional nanostructure on the mean inner potential of gold catalysts supported on titanium oxide using electron holography and high-resolution electron microscopy (HREM). The contact angle of the gold particles on the titanium oxide tended to be over 90° for gold particles with a size of over 5 nm, and below 90° for a size of below 2 nm. This decreasing change in the contact angle (morphology) acts to increase the perimeter and hence the area of the interface between the gold and titanium oxide support, which is considered to be an active site for CO oxidation. The mean inner potential of the gold particles also changed as their size decreased. The value of the inner potential of gold, which is approximately 25 V in bulk state, rose to over 40 V when the size of the gold particles was less than 2 nm. This phenomenon indicates the existence of a charge transfer at the interface between gold and titanium oxide. The 3-D structure change and the inner potential change should be attributed to the specific electronic structure at the interface, owing to both the “nano size effect” and the “hetero-interface effect.”


1996 ◽  
Vol 118 (2) ◽  
pp. 347-352 ◽  
Author(s):  
R. G. Dominy ◽  
D. A. Kirkham

Interturbine diffusers provide continuity between HP and LP turbines while diffusing the flow upstream of the LP turbine. Increasing the mean turbine diameter offers the potential advantage of reducing the flow factor in the following stages, leading to increased efficiency. The flows associated with these interturbine diffusers differ from those in simple annular diffusers both as a consequence of their high-curvature S-shaped geometry and of the presence of wakes created by the upstream turbine. It is shown that even the simplest two-dimensional wakes result in significantly modified flows through such ducts. These introduce strong secondary flows demonstrating that fully three-dimensional, viscous analysis methods are essential for correct performance modeling.


Author(s):  
Daphne Schönegg ◽  
Raphael Ferrari ◽  
Julian Ebner ◽  
Michael Blumer ◽  
Martin Lanzer ◽  
...  

Abstract Purpose The close topographic relationship between vascular and osseous structures in the condylar and subcondylar region and marked variability in the arterial course has been revealed by both imaging and cadaveric studies. This study aimed to verify the previously published information in a large sample and to determine a safe surgical region. Methods We analyzed the three-dimensional time-of-flight magnetic resonance angiography images of 300 individuals. Results The mean distance between the middle meningeal artery and the apex of the condyle or the most medial point of the condyle was 18.8 mm (range: 11.2–25.9 mm) or 14.5 mm (range: 8.8–22.9 mm) respectively. The course of the maxillary artery relative to the lateral pterygoid muscle was medial in 45.7% of cases and lateral in 54.3%. An asymmetric course was evident in 66 patients (22%). The mean distance between the maxillary artery and condylar process at the deepest point of the mandibular notch was 6.2 mm in sides exhibiting a medial course (range: 3.7–9.8 mm) and 6.6 mm in sides exhibiting a lateral course (range: 3.9–10.4 mm). The distances were significantly influenced by age, gender, and the course of the maxillary artery. Conclusion Our study emphasizes the marked inter- and intra-individual variability of the maxillary and middle meningeal arterial courses. We confirmed the proximity of the arteries to the condylar process. Extensive surgical experience and thorough preparation for each individual case are essential to prevent iatrogenic vascular injury.


Water ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 1718
Author(s):  
Hasan Zobeyer ◽  
Abul B. M. Baki ◽  
Saika Nowshin Nowrin

The flow hydrodynamics around a single cylinder differ significantly from the flow fields around two cylinders in a tandem or side-by-side arrangement. In this study, the experimental results on the mean and turbulence characteristics of flow generated by a pair of cylinders placed in tandem in an open-channel flume are presented. An acoustic Doppler velocimeter (ADV) was used to measure the instantaneous three-dimensional velocity components. This study investigated the effect of cylinder spacing at 3D, 6D, and 9D (center to center) distances on the mean and turbulent flow profiles and the distribution of near-bed shear stress behind the tandem cylinders in the plane of symmetry, where D is the cylinder diameter. The results revealed that the downstream cylinder influenced the flow development between cylinders (i.e., midstream) with 3D, 6D, and 9D spacing. However, the downstream cylinder controlled the flow recirculation length midstream for the 3D distance and showed zero interruption in the 6D and 9D distances. The peak of the turbulent metrics generally occurred near the end of the recirculation zone in all scenarios.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rino Saiga ◽  
Masayuki Uesugi ◽  
Akihisa Takeuchi ◽  
Kentaro Uesugi ◽  
Yoshio Suzuki ◽  
...  

AbstractBrain blood vessels constitute a micrometer-scale vascular network responsible for supply of oxygen and nutrition. In this study, we analyzed cerebral tissues of the anterior cingulate cortex and superior temporal gyrus of schizophrenia cases and age/gender-matched controls by using synchrotron radiation microtomography or micro-CT in order to examine the three-dimensional structure of cerebral vessels. Over 1 m of cerebral blood vessels was traced to build Cartesian-coordinate models, which were then used for calculating structural parameters including the diameter and curvature of the vessels. The distribution of vessel outer diameters showed a peak at 7–9 μm, corresponding to the diameter of the capillaries. Mean curvatures of the capillary vessels showed a significant correlation to the mean curvatures of neurites, while the mean capillary diameter was almost constant, independent of the cases. Our previous studies indicated that the neurites of schizophrenia cases are thin and tortuous compared to controls. The curved capillaries with a constant diameter should occupy a nearly constant volume, while neurons suffering from neurite thinning should have reduced volumes, resulting in a volumetric imbalance between the neurons and the vessels. We suggest that the observed structural correlation between neurons and blood vessels is related to neurovascular abnormalities in schizophrenia.


Author(s):  
Tran Anh Quynh ◽  
Pham Duy Hien ◽  
Le Quang Du ◽  
Le Hoang Long ◽  
Nguyen Thi Ngoc Tran ◽  
...  

AbstractRobotic surgery offers three-dimensional visualization and precision of movement that could be of great value to gastrointestinal surgeons. There were many previous reports on robotic technology in performing Soave colonic resection and pull-through for Hirschsprung’s disease in children. This study described the follow-up of the Robotic-assisted Soave procedure for Hirschsprung’s disease in children. Robotic-assisted endorectal pull-through was performed using three robotic arms and an additional 5-mm trocar. The ganglionic and aganglionic segments were initially identified by seromuscular biopsies. The rest of the procedure was carried out according to the Soave procedure. We left a short rectal seromuscular sleeve of 1.5–2 cm above the dentate line. From December 2014 to December 2017, 55 pediatric patients were operated on. Age ranged from 6 months to 10 years old (median = 24.5 months). The aganglionic segment was located in the rectum (n = 38), the sigmoid colon (n = 13), and the left colon (n = 4). The mean total operative time was 93.2 ± 35 min (ranging from 80 to 180 min). Minimal blood was lost during the surgery. During the follow-up period, 41 patients (74.6%) had 1–2 defecations per day, 12 patients (21.8%) had 3–4 defecations per day, and 2 patients (3.6%) had more than 4 defecations per day. Fecal incontinence, enterocolitis, and mild soiling occurred in three (5.4%), four (7.3%), and two pediatric patients, respectively. Robotic-assisted Soave procedure for Hirschsprung’s disease in children is a safe and effective technique. However, a skilled robotic surgical team and procedural modifications are needed.


2021 ◽  
Vol 9 (6) ◽  
pp. 585
Author(s):  
Minghao Wu ◽  
Leen De Vos ◽  
Carlos Emilio Arboleda Chavez ◽  
Vasiliki Stratigaki ◽  
Maximilian Streicher ◽  
...  

The present work introduces an analysis of the measurement and model effects that exist in monopile scour protection experiments with repeated small scale tests. The damage erosion is calculated using the three dimensional global damage number S3D and subarea damage number S3D,i. Results show that the standard deviation of the global damage number σ(S3D)=0.257 and is approximately 20% of the mean S3D, and the standard deviation of the subarea damage number σ(S3D,i)=0.42 which can be up to 33% of the mean S3D. The irreproducible maximum wave height, chaotic flow field and non-repeatable armour layer construction are regarded as the main reasons for the occurrence of strong model effects. The measurement effects are limited to σ(S3D)=0.039 and σ(S3D,i)=0.083, which are minor compared to the model effects.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tomoyo Y. Irie ◽  
Tohru Irie ◽  
Alejandro A. Espinoza Orías ◽  
Kazuyuki Segami ◽  
Norimasa Iwasaki ◽  
...  

AbstractThis study investigated in vivo the three-dimensional distribution of CT attenuation in the lumbar spine pedicle wall measured in Hounsfield Unit (HU). Seventy-five volunteers underwent clinical lumbar spine CT scans. Data was analyzed with custom-written software to determine the regional variation in pedicle wall attenuation values. A cylindrical coordinate system oriented along the pedicle’s long axis was used to calculate the pedicular wall attenuation distribution three-dimensionally and the highest attenuation value was identified. The pedicular cross-section was divided into four quadrants: lateral, medial, cranial, and caudal. The mean HU value for each quadrant was calculated for all lumbar spine levels (L1–5). The pedicle wall attenuation was analyzed by gender, age, spinal levels and anatomical quadrant. The mean HU values of the pedicle wall at L1 and L5 were significantly lower than the values between L2–4 in both genders and in both age groups. Furthermore, the medial quadrant showed higher HU values than the lateral quadrant at all levels and the caudal quadrant showed higher HU values at L1–3 and lower HU values at L4–5 than the cranial quadrant. These findings may explain why there is a higher incidence of pedicle screw breach in the pedicle lateral wall.


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