scholarly journals An Unusual Long-Term Survey of a Patient with Widespread Malignant Urachal Tumor, Not Given Chemotherapy or Radiotherapy

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Tugrul Ormeci ◽  
Murat Can Kiremit ◽  
Bulent Erkurt ◽  
Aslı Örmeci
Keyword(s):  
Local Recurrence ◽  
Total Colectomy ◽  
Surgical Excision ◽  
Primary Treatment ◽  
Partial Cystectomy ◽  
Fetal Life ◽  
Urachal Carcinoma ◽  
Aggressive Tumors ◽  
Long Term Survey

The urachus establishes a connection between the dome of the bladder and the umbilicus throughout fetal life. If the urachus does not close completely, malignancy is a potential complication. The primary treatment for malignant urachal tumor is surgical excision. A 61-year-old male patient diagnosed with urachal carcinoma had undergone partial cystectomy 25 years previously. Twenty years later, local recurrence was treated with another partial cystectomy without umbilical remnant excision. Recurrence at the umbilical site was excised 2 years later, but intraperitoneal invasion had occurred, and the patient underwent a total colectomy at that time. Local disease and disseminated metastases in the thorax and intra- and extraperitoneal areas were noted upon admission to our hospital. Urachal carcinomas are usually aggressive tumors, and surgical treatment should include partial or radical cystectomy and excision of the urachus and umbilicus, to prevent local recurrence and distant metastasis.

Mucinous Cystadenocarcinoma of the Breast: Report of 2 Cases Including One With Long-Term Local Recurrence

2018 ◽  
Vol 26 (8) ◽  
pp. 749-757 ◽  
Author(s):  
Anupma Nayak ◽  
Ira J. Bleiweiss ◽  
Kimberly Dumoff ◽  
Tawfiqul A. Bhuiya
Keyword(s):  
Gastrointestinal Tract ◽  
Local Recurrence ◽  
Surgical Excision ◽  
Mucinous Cystadenocarcinoma ◽  
Rare Tumor ◽  
Rare Entity

Primary mucinous cystadenocarcinoma (MCA) of breast is an exceedingly rare tumor with histologic resemblance to MCA arising in ovary, pancreas, and gastrointestinal tract. In this article, we present 2 additional cases of MCA of breast, one highlighting the diagnostic challenges of a rare entity that may potentially lead to unnecessary chemotherapy and the second case presenting with recurrence after 8 years of primary surgical excision defying the indolent behavior reported in the literature. To our knowledge, this is the first reported instance of such behavior.

scholarly journals Denosumab: A potential new treatment option for recurrent Aneurysmal Bone Cyst of the spine

SICOT-J ◽  
2019 ◽  
Vol 5 ◽  
pp. 10 ◽  
Author(s):  
Arvind G. Kulkarni ◽  
Ankit Patel
Keyword(s):  
Local Recurrence ◽  
Human Monoclonal Antibody ◽  
Bone Cyst ◽  
Surgical Excision ◽  
Long Term Results ◽  
Osteolytic Lesions ◽  
Short Period ◽  
New Treatment

ABCs are expansile osteolytic lesions typically containing blood-filled spaces separated by fibrous septae. Standard treatment includes surgical resection or curettage and packing; however, for some spinal lesions, the standard approach is not optimal. One therapeutic strategy is to treat spinal ABC with an agent that targets a pathway that is dysregulated in a disease with similar pathophysiology. Denosumab, a human monoclonal antibody to RANKL is effective in the treatment of GCT's. Spinal ABCs are a therapeutic challenge and local recurrence is a concern. We report a case of aggressive recurrent ABC of dorsal spine in a 14-year old female with progressive neurologic deficit who underwent surgical excision and decompression with a recurrence in a short period for which a decompression and fixation was done. She had a recurrence after an asymptomatic period of 6 months and neurologic worsening. Having ruled out use of embolization and radiotherapy, a remission was achieved by treatment with Denosumab using the regimen for GCTs for a duration of 6 months. Follow-up MRI and CT scans at 24 months following inception of Denosumab depicted complete resolution and no recurrence. We conclude that Denosumab can result in symptomatic and radiological improvement in the recurrent locally aggressive ABC and may be useful in selected cases. Long-term results are mandatory to confirm the efficacy of Denosumab and to evaluate local recurrence after stopping Denosumab.

The Outcome of Treatment of Flexor Sheath (seed) Ganglia by a Percutaneous Partial Pulley Release

2017 ◽  
Vol 22 (02) ◽  
pp. 219-221
Author(s):  
David Lavalette ◽  
Grey Giddins
Keyword(s):  
Complete Resolution ◽  
Retrospective Cohort ◽  
Surgical Excision ◽  
Primary Treatment ◽  
Percutaneous Release ◽  
Long Term Follow Up ◽  
Local Tenderness ◽  
The Mean

Background: The aims of this study were to assess the safety and efficacy of a technique of partial percutaneous pulley release. Methods: A retrospective cohort study was undertaken treating adults with seed ganglia with a percutaneous pulley release. The patients were reviewed independently after a mean of 6 (range 6–36) months. Results: We treated 24 patients over a 3 year period. There were 14 women and ten men. The mean age was 39 (range 17-65) years. We were able to assess 21 patients with long term follow up. There was complete resolution in 14 (2/3) and partial resolution in four. The remaining three patients had persisting symptoms and requested open surgical excision. Apart from local tenderness and failure of resolution there were no complications of percutaneous pulley release. Conclusions: Bursting or aspiration of flexor sheath ganglia appears to be the best primary treatment. If the ganglion recurs, this study suggests a percutaneous release is safe and will resolve the symptoms in most patients.

Vulvar soft tissue tumors

2004 ◽  
Vol 14 (1) ◽  
pp. 94-99
Author(s):  
K. A. Behranwala ◽  
B. Latifaj ◽  
P. Blake ◽  
D. P. J. Barton ◽  
J. H. Shepherd ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Local Recurrence ◽  
Surgical Excision ◽  
Primary Treatment ◽  
Soft Tissue Tumors ◽  
Soft Tissue Neoplasms ◽  
Low Grade ◽  
Aggressive Angiomyxoma ◽  
Royal Marsden Hospital ◽  
Histologic Types

ObjectiveTo report our incidence of soft tissue tumors at this site and to discuss various prognostic factors.MethodsAll patients with a diagnosis of vulvar soft tissue neoplasms were studied from a prospective database at the Royal Marsden Hospital between January 1985 and July 2001.ResultsSeventeen vulvar soft tissue neoplasms (11 malignant and six benign) were treated during this period. Leiomyosarcoma (n = 5) and aggressive angiomyxoma (n = 4) were the most frequent histologic types. According to the grade, there were four G3, three G2, three G1 and could not be assessed in one patient. Local recurrence occurred in six patients with sarcoma (three with high grade and one each with intermediate, low, and undetermined grade). In this group, five patients had negative microscopic margins and one patient had positive microscopic margins on excision. All three women with low-grade sarcomas are alive without evidence of disease. Three patients with aggressive angiomyxoma also had a local recurrence.ConclusionSurgical excision is the primary treatment where possible. The grade of the tumor is an important predictor for local recurrence and outcome. Aggressive angiomyxoma is a local problem. Leiomyosarcoma and aggressive angiomyxoma are the most frequent histologic types.

A rare angiosarcoma: retiform haemangioendothelioma

2011 ◽  
Vol 126 (2) ◽  
pp. 200-202 ◽  
Author(s):  
F O'Duffy ◽  
C Timon ◽  
M Toner
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Local Recurrence ◽  
Tumour Size ◽  
Surgical Excision ◽  
Primary Treatment ◽  
Low Grade ◽  
Node Metastasis ◽  
Primary Treatment Modality ◽  
High Local Recurrence Rate

AbstractObjective:We report the case of a rare angiosarcoma, retiform haemangioendothelioma, in an 18-year-old young man, which presented as a recurrent ulcerating lesion of the left pinna.Method:Case report and literature review of retiform haemangioendothelioma. This is a low grade angiosarcoma with a high local recurrence rate and low metastasis rate, and was first described in 1994 by Calonje et al.Results:This patient represents only the third report of lymph node metastasis in a case of retiform haemangioendothelioma. To date, 31 cases of the tumour have been reported. Histological diagnosis of this group of vascular neoplasms can be challenging, as their histopathological appearance is intermediate between haemangioma and angiosarcoma.Conclusion:Surgical excision remains the primary treatment modality, with adjuvant radiotherapy recommended in patients with large tumour size, local recurrence and lymph node metastasis, as seen in this case.

A comparison of radiotherapy and surgery as primary treatment in the management of T3 N0 M0 glottic tumours

1993 ◽  
Vol 107 (10) ◽  
pp. 912-915 ◽  
Author(s):  
D. Simpson ◽  
A. G. Robertson ◽  
D. Lamont
Keyword(s):  
Local Recurrence ◽  
Salvage Surgery ◽  
Squamous Carcinoma ◽  
Primary Treatment ◽  
Term Survival ◽  
Long Term Survival ◽  
Local Recurrences ◽  
Carcinoma Of Larynx

AbstractSeventy-four patients with Stage T3 NO MO squamous carcinoma of the glottis were treated initially by either surgery or radiotherapy between 1980 and 1985. The treatment adopted was determined by consultant preference. The long-term survival in both groups was approximately the same. Of 38 patients treated initially by radiotherapy, 25 had local recurrence. Fifteen of these underwent salvage surgery and 10 died of disease. Thirteen patients (33 per cent) retained their larynx. One of the major advantages of treating patients with stage T3 NO MO carcinoma of larynx by radiotherapy initially is that approximately one-third will retain their larynx. Local recurrences can usually be treated readily by salvage surgery.

309: Surgery of Urachal Carcinoma – Evaluation of Long Term Outcome

2004 ◽  
Vol 171 (4S) ◽  
pp. 81-81
Author(s):  
Michael Cohen ◽  
Bernard H. Bochner ◽  
Harry W. Herr
Keyword(s):  
Term Outcome ◽  
Urachal Carcinoma ◽  
Long Term Outcome

Electrocardiogram Recognition and Ablation of Atrial Tachycardia

2011 ◽  
Vol 3 (1) ◽  
pp. 80
Author(s):  
Alexander Feldman ◽  
Jonathan M Kalman ◽  
◽  
Keyword(s):  
Catheter Ablation ◽  
Atrial Tachycardia ◽  
Primary Treatment ◽  
P Wave ◽  
Wave Morphology ◽  
Focal Atrial Tachycardia ◽  
Mapping Techniques ◽  
Electrocardiogram Ecg ◽  
Surface Electrocardiogram

Focal atrial tachycardia (AT) is a relatively uncommon cause of supraventricular tachycardia, but when present is frequently difficult to treat medically. Atrial tachycardias tend to originate from anatomically determined atrial sites. The P-wave morphology on surface electrocardiogram (ECG) together with more sophisticated contemporary mapping techniques facilitates precise localisation and ablation of these ectopic foci. Catheter ablation of focal AT is associated with high long-term success and may be viewed as a primary treatment strategy in symptomatic patients.

scholarly journals Short stump and high anastomosis pull-through (SHiP) procedure for delayed coloanal anastomosis with no protective stoma for low rectal cancer

2021 ◽  
Vol 73 (2) ◽  
pp. 495-502
Author(s):  
Francesco Bianco ◽  
Paola Incollingo ◽  
Armando Falato ◽  
Silvia De Franciscis ◽  
Andrea Belli ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Local Recurrence ◽  
Coloanal Anastomosis ◽  
Functional Results ◽  
Anal Margin ◽  
Perioperative Mortality ◽  
The Mean ◽  
Pull Through ◽  
Protective Stoma

AbstractDespite advances in coloanal anastomosis techniques, satisfactory procedures completed without complications remain lacking. We investigated the effectiveness of our recently developed ‘Short stump and High anastomosis Pull-through’ (SHiP) procedure for delayed coloanal anastomosis without a stoma. In this retrospective study, we analysed functional outcomes, morbidity, and mortality rates and local recurrence of 37 patients treated using SHiP procedure, out of the 282 patients affected by rectal cancer treated in our institution between 2012 and 2020. The inclusion criterion was that the rectal cancer be located within 4 cm from the anal margin. One patient died of local and pulmonary recurrence after 6 years, one developed lung and liver metastases after 2 years, and one experienced local recurrence 2.5 years after surgery. No major leak, retraction, or ischaemia of the colonic stump occurred; the perioperative mortality rate was zero. Five patients (13.51%) had early complications. Stenosis of the anastomosis, which occurred in nine patients (24.3%), was the only long-term complication; only three (8.1%) were symptomatic and were treated with endoscopic dilation. The mean Wexner scores at 24 and 36 months were 8.3 and 8.1 points, respectively. At the 36-month check-up, six patients (24%) had major LARS, ten (40%) had minor LARS, and nine (36%) had no LARS. The functional results in terms of LARS were similar to those previously reported after immediate coloanal anastomosis with protective stoma. The SHiP procedure resulted in a drastic reduction in major complications, and none of the patients had a stoma.

A long-term survey on Mycobacterium tuberculosis complex in wild mammals from a bovine tuberculosis low prevalence area

2021 ◽  
Vol 67 (3) ◽  
Author(s):  
Lucía Varela-Castro ◽  
Xeider Gerrikagoitia ◽  
Vega Alvarez ◽  
María V. Geijo ◽  
Marta Barral ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Bovine Tuberculosis ◽  
Mycobacterium Tuberculosis Complex ◽  
Tuberculosis Complex ◽  
Wild Mammals ◽  
Low Prevalence ◽  
Long Term Survey
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