scholarly journals Comparison of Plasma Neurosteroid and Prolactin Levels in Patients with Schizophrenia and Healthy Individuals

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Forough Riahi ◽  
Maryam Izadi-mazidi ◽  
Ali Ghaffari ◽  
Elham Yousefi ◽  
Shahram Khademvatan
Keyword(s):  
Analysis Of Variance ◽  
Serum Testosterone ◽  
Cross Sectional Study ◽  
Serum Testosterone Level ◽  
First Episode ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hormone Levels ◽  
First Episode Schizophrenia

Background.The present study aimed to compare plasma levels of cortisol, testosterone, dehydroepiandrosterone (DHEA), and prolactin in patients with schizophrenia and healthy individuals.Method.A total of 100 patients with schizophrenia disorder (69 men and 31 women) and 190 healthy individuals (94 men and 96 women) participated in this cross-sectional study. They were tested for hormone levels and completed demographic questionnaires. Data were analyzed using multivariate analysis of variance (MANOVA) and one-way analysis of variance.Results.Serum testosterone level was significantly higher in men with schizophrenia than in healthy men. Women with schizophrenia had a significantly higher level of testosterone and lower level of prolactin compared to healthy women. There were no significant differences in hormone levels across various subtypes of schizophrenia. No significant differences also were observed in hormones levels in patients with first-episode schizophrenia disorder compared to those in patients with recurrent episodes.Conclusion.This study indicated that abnormal testosterone and prolactin levels might be associated with pathophysiology of schizophrenia disorder.

Poster #134 A CROSS SECTIONAL STUDY OF NOVEL P300 IN PRODROMES AND FIRST EPISODE SCHIZOPHRENIA

2012 ◽  
Vol 136 ◽  
pp. S234
Author(s):  
Elisabetta C. del Re ◽  
Margaret Niznikiewicz ◽  
Tracy Petryshen ◽  
Robert W. McCarley
Keyword(s):  
Cross Sectional Study ◽  
First Episode ◽  
Sectional Study ◽  
Cross Sectional ◽  
First Episode Schizophrenia

Elevated Platelet Parameter in First-Episode Schizophrenia Patients: A Cross-Sectional Study

2020 ◽  
Vol 40 (11) ◽  
pp. 524-529
Author(s):  
Qi Yu ◽  
Wujin Weng ◽  
Hongfei Zhou ◽  
Yamei Tang ◽  
Shan Ding ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
First Episode ◽  
Sectional Study ◽  
Cross Sectional ◽  
Platelet Parameter ◽  
First Episode Schizophrenia

A cross-sectional study of medication compliance: The west London first-episode schizophrenia study

2000 ◽  
Vol 41 (1) ◽  
pp. 223
Author(s):  
S.H. Mutsatsa ◽  
T.R.E. Barnes ◽  
S.B. Hutton ◽  
I. Cuthbert ◽  
E.M. Joyce
Keyword(s):  
Medication Compliance ◽  
Cross Sectional Study ◽  
First Episode ◽  
Sectional Study ◽  
The West ◽  
Cross Sectional ◽  
First Episode Schizophrenia

scholarly journals Testosterone substitution of hypogonadal men prevents the age-dependent increases in body mass index, body fat and leptin seen in healthy ageing men: results of a cross-sectional study

2002 ◽  
pp. 505-511 ◽  
Author(s):  
C Rolf ◽  
S von Eckardstein ◽  
U Koken ◽  
E Nieschlag
Keyword(s):  
Fat Mass ◽  
Serum Testosterone ◽  
Cross Sectional Study ◽  
Fat Content ◽  
Sectional Study ◽  
Cross Sectional ◽  
Serum Leptin ◽  
Testosterone Substitution ◽  
Age Dependent ◽  
Total Fat

INTRODUCTION: In healthy men, body weight and total fat content increase with advancing age, while serum testosterone levels decrease. In order to elucidate whether a causal relationship between these phenomena exists, we investigated the influence of testosterone or human chorionic gonadotrophin substitution on body mass index (BMI), total fat mass and serum leptin in testosterone-treated and untreated hypogonadal patients in comparison with ageing eugonadal men. METHODS: In a cross-sectional study, the inter-relationships of body weight, total fat mass, serum sex hormones and leptin were analysed in untreated hypogonadal men (n=24; age 19-65 years), treated hypogonadal men (n=61; age 20-67 years) and healthy eugonadal men (n=60; age 24-78 years). Total fat mass was assessed by bioimpedance measurement. Univariate and multiple linear regression analysis was used to detect possible differences. RESULTS: In eugonadal men, serum testosterone levels decreased with advancing age (correlation coefficients: r=-0.71; P<0.0001), while BMI (r=0.39; P=0.002), total fat content (r=0.51; P<0.0001) and leptin (r=0.48; P<0.0001) increased significantly. In untreated hypogonadal patients, an increase in BMI (r=0.50; P=0.013) and total fat mass (r=0.41; P=0.044) was also observed with advancing age. However, in substituted hypogonadal patients, no age-dependent change in BMI (r=0.067; P=0.606), body fat content (r=-0.083; P=0.522), serum testosterone (r=-0,071; P=0.59) or serum leptin (r=-0.23; P=0.176) was found. CONCLUSION: Since testosterone-substituted older hypogonadal men show BMI and fat mass similar to those of younger eugonadal men and since non-treated hypogonadal men are similar to normal ageing men, testosterone appears to be an important factor contributing to these changes. Thus ageing men should benefit from testosterone substitution as far as body composition is concerned.

scholarly journals Vertebrogenic back pain syndrome in children 9–17 years with spinal deformities

2019 ◽  
Vol 7 (1) ◽  
pp. 5-14 ◽  
Author(s):  
Marchel S. Vetrile ◽  
Aleksandr A. Kuleshov ◽  
Nikolai A. Eskin ◽  
Mikhail B. Tsykunov ◽  
Alexey I. Kokorev ◽  
...  
Keyword(s):  
Back Pain ◽  
Children And Adolescents ◽  
Pain Syndrome ◽  
Cross Sectional Study ◽  
Spinal Deformities ◽  
Age Group ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Cross Sectional ◽  
X Ray

Aim. We defined the prevalence of back pain in children and adolescents aged 917 years with spinal deformities. Material and methods. The cross-sectional study included 230 students with different spinal deformities aged 917 years. The prevalence of back pain, intensity, location, and situations in which it occurred were assessed via questionnaire. Results. Among 230 respondents, 186 (80.9%) admitted that they had experienced back pain (mainly in the lumbar spine) at various frequencies within the year preceding the study. Mild pain was prevalent (71% of respondents). Girls experienced back pain significantly more frequently than boys. Conclusions. Back pain in children and adolescents requires clinical and instrumental examination, including X-ray. Back pain is a frequent phenomenon in children with different spinal deformities. Тhe incidence of pain in children and adolescents with spinal deformities in our study is statistically higher than that of healthy individuals of the same age group.

Width and thickness of the gingiva in periodontally healthy individuals in a central Indian population: a cross-sectional study

2021 ◽  
Author(s):  
Pradeep S. Anand ◽  
Abhinav Bansal ◽  
Balaji R. Shenoi ◽  
Kavitha P. Kamath ◽  
Namitha P. Kamath ◽  
...  
Keyword(s):  
Indian Population ◽  
Cross Sectional Study ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Cross Sectional
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