scholarly journals Evaluation of Early Cholecystectomy versus Delayed Cholecystectomy in the Treatment of Acute Cholecystitis

HPB Surgery ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Miguel Sánchez-Carrasco ◽  
Juan C. Rodríguez-Sanjuán ◽  
Fernando Martín-Acebes ◽  
Francisco J. Llorca-Díaz ◽  
Manuel Gómez-Fleitas ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Acute Cholecystitis ◽  
Operating Time ◽  
Cost Savings ◽  
Direct Costs ◽  
Early Cholecystectomy ◽  
Delayed Cholecystectomy ◽  
Appropriate Treatment ◽  
Costs Of Treatment ◽  
Hospital Morbidity

Objective. To evaluate if early cholecystectomy (EC) is the most appropriate treatment for acute cholecystitis compared to delayed cholecystectomy (DC). Patients and Methods. A retrospective cohort study of 1043 patients was carried out, with a group of 531 EC cases and a group of 512 DC patients. The following parameters were recorded: (1) postoperative hospital morbidity, (2) hospital mortality, (3) days of hospital stay, (4) readmissions, (5) admission to the Intensive Care Unit (ICU), (6) type of surgery, (7) operating time, and (8) reoperations. In addition, we estimated the direct cost savings of implementing an EC program. Results. The overall morbidity of the EC group (29.9%) was significantly lower than the DC group (38.7%). EC demonstrated significantly better results than DC in days of hospital stay (8.9 versus 15.8 days), readmission percentage (6.8% versus 21.9%), and percentage of ICU admission (2.3% versus 7.8%), which can result in reducing the direct costs. The patients who benefited most from an EC were those with a Charlson index > 3. Conclusions. EC is safe in patients with acute cholecystitis and could lead to a reduction in the direct costs of treatment.

scholarly journals Early versus delayed cholecystectomy in acute cholecystitis: a comparative study in a tertiary care hospital

2020 ◽  
Vol 7 (8) ◽  
pp. 2656
Author(s):  
Jamal Uddin Ahmed ◽  
Subal Rajbongshi ◽  
Najim Hiquemat
Keyword(s):  
Acute Cholecystitis ◽  
Elective Surgery ◽  
Tertiary Care ◽  
Definitive Treatment ◽  
P Value ◽  
Care Hospital ◽  
Early Cholecystectomy ◽  
Delayed Cholecystectomy ◽  
Surgery Group ◽  
Duration Of Surgery

Background: For patients with acute cholecystitis the timing of operative intervention has two broad approaches- early cholecystectomy and elective or delayed cholecystectomy. The main advantage of early cholecystectomy is that, it offers a definitive treatment during the same admission and avoids the problem of failed conservative treatment. The present study is an endeavour to discuss and to compare the outcome of management of acute cholecystitis with early and delayed cholecystectomy.Methods: 100 patients with clinical diagnosis of acute cholecystitis, admitted in the surgical wards of Gauhati Medical College and Hospital during the period of 1st July 2017 to 30th June 2018 were selected for the study. 40 patients underwent early cholecystectomy (within 7 days of onset of symptoms) and 60 patients underwent elective or late cholecystectomy (after a gap of 6-8 weeks from the acute attack).Results: In the present series the average duration of surgery was 90.37±11.96 minutes in the early group and 65.3±7.83 minutes for the elective group which is found to be statistically significant (p value<0.05). In the early surgery group 8.33% required conversion to open surgery. In the elective surgery group 3.63% required conversion. Wound infection, biliary leakage, bile duct injury, and respiratory tract infection was found to be statistically not significant between the two groups.Conclusions: Early cholecystectomy is feasible and safe for acute cholecystitis and is better method of treatment because of its shorter hospital stay, which is a major economic benefit to both the patient and health care system.

Timing of Laparoscopic Cholecystectomy for Acute Cholecystitis: Evidence to Support a Proposal for an Early Interval Surgery

2007 ◽  
Vol 73 (11) ◽  
pp. 1188-1192 ◽  
Author(s):  
Jee K. Low ◽  
Paul Barrow ◽  
Anas Owera ◽  
Basil J. Ammori
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Hospital Stay ◽  
Acute Cholecystitis ◽  
Operating Time ◽  
Cost Effective ◽  
Delayed Surgery ◽  
Urgent Surgery ◽  
Bile Duct Injuries ◽  
Total Hospital Stay ◽  
Interval Surgery

We evaluated the safety and feasibility of delayed urgent laparoscopic cholecystectomy (LC) performed beyond 72 hours to overcome the logistical difficulties in performing early urgent LC within 72 hours of admission with acute cholecystitis (AC), and to avoid earlier readmission with recurrent AC in patients awaiting delayed interval. Patients admitted with AC were scheduled for urgent LC. Patients who underwent early urgent LC were compared with those who had delayed urgent surgery. Fifty consecutive patients underwent urgent LC for AC within 2 weeks of admission. There were no conversions and no bile duct injuries. Delayed surgery (n = 36) neither prolonged operating time (90 vs 85 minutes), nor increased operative morbidity (9.7% vs 7.7%) or mortality (2.4% vs 7.7%) compared with early surgery (n = 14). Although delayed surgery was associated with shorter postoperative hospital stay (1 vs 2 days, P = 0.029), it prolonged total hospital stay (9 vs 5 days, P < 0.0001). Delay of LC beyond 72 hours neither increases operative difficulty nor prolongs recovery. It might be more cost effective to schedule patients who could not undergo early urgent LC but are responding to conservative treatment for an early interval LC within 2 weeks of presentation with AC.

scholarly journals Acute cholecystitis - early or delayed cholecystectomy

2002 ◽  
Vol 55 (3-4) ◽  
pp. 135-139 ◽  
Author(s):  
Goran Petakovic ◽  
Milan Korica ◽  
Sava Gavrilovic
Keyword(s):  
Sick Leave ◽  
Acute Cholecystitis ◽  
Late Results ◽  
Chronic Cholecystitis ◽  
Home Treatment ◽  
Endocrine Surgery ◽  
Early Cholecystectomy ◽  
Delayed Cholecystectomy ◽  
Group I ◽  
Group Ii

Introduction In our population biliary tract diseases are the most frequent surgical entity. If the diagnosis of acute cholecystitis is relatively clear and the time from onset of the disease does not exceed 72 hours, early cholecystectomy is recommended. The aim of i his prospective study was to use certain analytical procedures in order to compare early and late results of early and delayed cholecystectomy. Material and methods 240 patients were divided into two groups: Group 1: patients treated by early cholecystectomy and Group II: patients treated by delayed cholecystectomy. We compared the following: intraoperative findings, postoperative morbidity and mortality complications, average number of patient-days and histopathological changes. Results During the investigated period (1998-1999), 599 (35,95%) patients with acute and 1.067 (64.05%) patients with chronic cholecystitis were treated at the Clinic of Abdominal and Endocrine Surgery of the Clinical Center Novi Sad. Out of 599 patients with acute cholecystitis, 489 (81.63%) patients underwent surgery, whereas 1S0 (18.37%) were treated conservatively. In regard to chronic cholecystitis, 963 (90.25%) patients were surgically treated, and 104 (9.75%) patients were conservatively treated. All patients from Group I were operated within 24-48 hours from onset of the disease or during 24 hours of hospitalization. They were hospitalized due to signs of cholecystitis for the first time, whereas this was the second hospitalization for all patients from Group II, 42?2.3 days after first hospitalization on average. Regarding sick leave in Group I patients it was calculated as follows: hospital days + home treatment and it made 32?3.7 days. In Group II it was calculated as follows: first hospitalization + home treatment + second hospitalization + home treatment making 53?6.7 days. Conclusions The number and type of early and late complications in Group II patients justifies early cholecystectomy; in acute cholecystitis, cholecystectomy should be performed within 24 - 48 hours from the onset of the disease; in regard to late, early cholecyslectomies are characterized by significantly shorter period of recovery and sick leave.

scholarly journals Compare the effectiveness of early versus delayed laparoscopic cholecystectomy in acute calculus cholecystitis

2018 ◽  
Vol 5 (2) ◽  
pp. 695
Author(s):  
Madhu C. P. ◽  
Senthil Kumar R. M.
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Hospital Stay ◽  
Postoperative Morbidity ◽  
Intraoperative Complications ◽  
Cost Savings ◽  
Delayed Laparoscopic Cholecystectomy ◽  
Delayed Group ◽  
Costs Of Treatment ◽  
Time Of Presentation ◽  
Antibiotic Coverage

Background: To compare the effectiveness of early versus delayed laparoscopic cholecystectomy in acute calculous cholecystitis.Methods: 30 Cases each in early group and delayed group were selected according to their time of presentation of their first symptom. Parameters were recorded intraoperative complications, timing of surgery, postoperative morbidity, days of hospital stay, days of antibiotic coverage, conversion to open and readmissions. In addition, author estimated the direct cost savings of implementing an ELC programResults: The overall morbidity and complications are less in ELC compared to DLC. Mean number of hospital stay is less in ELC (4.90%) whereas DLC (6.30%). Mean number of days of antibiotic coverage less in ELC (3.9 days) to DLC (5.30 days). Mean operative time is less in ELC (60 minutes) and DLC (82 minutes). Overall the complications, morbidity, mortality, ICU admissions, readmissions are less in early laparoscopic cholecystectomy.Conclusions: ELC is safe in patients with acute cholecystitis and could lead to a reduction in the direct costs of treatment.

scholarly journals A comparative study of interval cholecystectomy and early cholecystectomy in acute cholecystitis

2020 ◽  
Vol 7 (5) ◽  
pp. 1419
Author(s):  
Gursimranjit Singh ◽  
Rana Ranjit Singh ◽  
Darpan Bansal
Keyword(s):  
Hospital Stay ◽  
Acute Cholecystitis ◽  
Early Surgery ◽  
Total Hospital ◽  
Total Cost ◽  
Early Cholecystectomy ◽  
Total Hospital Stay ◽  
Significant Difference ◽  
Delayed Group ◽  
Day By Day

Background: In the whole world including India, the incidence of acute cholecystitis is increasing day by day. Gall stones are the most common cause of acute cholecystitis in 90-95% of the cases. The management of acute cholecystitis was conservative earlier but now there are studies recommending early surgery as the treatment of choice.Methods: Our study was conducted on 60 patients divided into two groups of 30 each to compare the results of early surgery with the delayed surgery.Results: The overall post-operative complication rate was same in both the groups but there was significant difference in the total hospital stay and total cost of the therapy in both the groups. The average total hospital stay in early group was 6.50±4.44 days and in delayed group was 10.80±5.55 days without including the number of days in non-operating admission.Conclusions: So, early cholecystectomy was found to be more economical with less total hospital stay and less total cost of the therapy than interval cholecystectomy in acute cholecystitis. 

scholarly journals Timing of early laparoscopic cholecystectomy for acute calculous cholecystitis revised: Protocol of a systematic review and meta-analysis of results

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Giuseppe Borzellino ◽  
Safi Khuri ◽  
Michele Pisano ◽  
Subhi Mansour ◽  
Niccolò Allievi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Laparoscopic Cholecystectomy ◽  
Early Intervention ◽  
Conservative Treatment ◽  
Acute Cholecystitis ◽  
Meta Analysis ◽  
Early Cholecystectomy ◽  
Early Laparoscopic Cholecystectomy ◽  
Pooled Data ◽  
Delayed Cholecystectomy

Abstract Background Early laparoscopic cholecystectomy has been adopted as the treatment of choice for acute cholecystitis due to a shorter hospital length of stay and no increased morbidity when compared to delayed cholecystectomy. However, randomised studies and meta-analysis report a wide array of timings of early cholecystectomy, most of them set at 72 h following admission. Setting early cholecystectomy at 72 h or even later may influence analysis due to a shift towards a more balanced comparison. At this time, the rate of resolving acute cholecystitis and the rate of ongoing acute process because of failed conservative treatment could be not so different when compared to those operated with a delayed timing of 6–12 weeks. As a result, randomised comparison with such timing for early cholecystectomy and meta-analysis including such studies may have missed a possible advantage of an early cholecystectomy performed within 24 h of the admission, when conservative treatment failure has less potential effects on morbidity. This review will explore pooled data focused on randomised studies with a set timing of early cholecystectomy as a maximum of 24 h following admission, with the aim of verifying the hypothesis that cholecystectomy within 24 h may report a lower post-operative complication rate compared to a delayed intervention. Methods A systematic review of the literature will identify randomised clinical studies that compared early and delayed cholecystectomy. Pooled data from studies that settled the early intervention within 24 h from admission will be explored and compared in a sub-group analysis with pooled data of studies that settled early intervention as more than 24 h. Discussion This paper will not provide evidence strong enough to change the clinical practice, but in case the hypothesis is verified, it will invite to re-consider the timing of early cholecystectomy and might promote future clinical research focusing on an accurate definition of timing for early cholecystectomy for acute cholecystitis.

scholarly journals Percutaneous Cholecystostomy is a Reasonable Alternative for the Treatment of Acute Cholecystitis in Critically Ill Patients: a Single Center Analysis

2019 ◽  
Vol 18 (4) ◽  
pp. 246-253
Author(s):  
Povilas Ignatavicius ◽  
Mindaugas Kiudelis ◽  
Inga Dekeryte ◽  
Deimante Mikuckyte ◽  
Jolita Sasnauskaite ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Acute Cholecystitis ◽  
Critically Ill ◽  
Treatment Option ◽  
Critically Ill Patients ◽  
Definitive Treatment ◽  
Safe Procedure ◽  
Percutaneous Cholecystostomy ◽  
Delayed Cholecystectomy ◽  
Alternative Treatment Option

Background / objective. Laparoscopic cholecystectomy is a safe procedure and the treatment of choice for acute cholecystitis. As an alternative treatment option in critically ill patients percutaneous cholecystostomy (PC) is performed.Methods. Retrospective review of patients who had undergone PC from 2008 to 2017 at the Department of Surgery, Hospital of Lithuanian University of Health Sciences Kaunas Clinics. Patients were reviewed for demographic features, laboratory tests, ASA class, complications, outcomes, hospital stay and mortality rate.Results. Fifty-four patients were included in the study. Forty patients (74%) were ASA III and ten patients (18.5%) – ASA IV. Statistically signi­ficant decrease in white blood cell count (from 14.26±6.61 to 8.65±5.15) and C-reactive protein level (from 226.22±106.60 to 51.91±63.70) following PC was observed. The median hospital stay was 13.06 (range 2–68) days and 30-day mortality rate 13%. There were no deaths directly related to procedure. For eleven patients (20.4%) delayed cholecystectomy was scheduled.Conclusions. PC is a reasonable treatment option for high-risk patients with acute cholecystitis and co-morbidities. It can be used as a temporizing treatment option or as a definitive treatment with a low number of delayed cholecystectomies.

scholarly journals Outcome of early laparoscopic cholecystectomy versus delayed laparoscopic cholecystectomy for patients with acute cholecystitis

2020 ◽  
Vol 7 (4) ◽  
pp. 1212 ◽  
Author(s):  
Zahid Mohd Rather ◽  
Nighat Ara Majid ◽  
Mohd Nazrull Islam ◽  
Raja Waseem Mohd
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Hospital Stay ◽  
Acute Cholecystitis ◽  
Operating Time ◽  
Total Hospital ◽  
Average Hospital ◽  
Early Laparoscopic Cholecystectomy ◽  
Total Hospital Stay ◽  
Delayed Laparoscopic Cholecystectomy ◽  
The Cost

Background: This prospective randomized study was undertaken to to assess the outcomes of early versus delayed cholecystectomy for patient’s acute cholecystitis.Methods: 70 patients with acute cholecystitis were prospectively randomized to either an early laparoscopic cholecystectomy (n=35) or a delayed laparoscopic cholecystectomy group (n=35). The mean operative time, conversion rate, total hospital stay, intra-operative and post-operative complications, average hospital cost were evaluated between the two groups.Results: A total of 70 patients were enrolled, 35 patients in each group. There was no significant difference in the conversion rates (early, 8.57% vs delayed, 5.71%) and postoperative complications (early, 25% vs delayed, 20%). At the cost of an increased operating time (early, 81 minutes vs delayed, 78 minutes) and blood loss (early, 180.33ml vs delayed, 108.00 ml), early laparoscopic cholecytectomy significantly shortened the total hospital stay (early, 1.5 days vs. delayed, 7.95 days) and  average hospital cost (early 9240 INR vs delayed, 12251 INR).Conclusions: The safety and efficacy of early and delayed laparoscopic cholecystectomy for acute cholecystitis were comparable in terms of morality, morbidity and conversion rate. However early laparoscopic cholecystectomy allows significantly shorter  total hospital stay and reduction in days away from work at the cost of  longer operating time and blood loss and offers definitive treatment at initial admission. Moreover it avoids repeated admissions for recurrent symptoms has both medical as well as socioeconomic benefits and should be the preferred approach for patients managed by surgeons with adequate experience in laparoscopic cholecystectomy.

Omental Infarction: A Case Treated with Laparoscopic Surgery

2019 ◽  
pp. 1-3
Author(s):  
Bertrand Ng ◽  
Arafat Yasser
Keyword(s):  
Diabetes Mellitus ◽  
Laparoscopic Surgery ◽  
Hospital Stay ◽  
Acute Cholecystitis ◽  
Inflammatory Markers ◽  
Acute Onset ◽  
Laparoscopy Surgery ◽  
History Of ◽  
Background History ◽  
The Right

Omental infarct is a rare cause of an acute abdomen that arises from an interruption of blood supply to the omentum. Here, we present a case of omental infarct in a 67-year-old gentleman with background history of diabetes mellitus who present unusually with a severe acute onset right hypochondrium pain. Examination revealed that he was tender to touch at the right and was having localized guarding. His inflammatory markers were normal. He was successfully treated with laparoscopy surgery and he was subsequently discharged the following day. Omental infarct cases with right hypochondrium pain can sometimes mimicked acute cholecystitis and management includes laparoscopic surgery which can hasten symptoms resolution and reduces hospital stay, however recommendation for surgery has to be balanced with anesthetics risk and complication of the surgery itself.

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