scholarly journals Spider Bite: A Rare Case of Acute Necrotic Arachnidism with Rapid and Fatal Evolution

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Mario Pezzi ◽  
Anna Maria Giglio ◽  
Annamaria Scozzafava ◽  
Orazio Filippelli ◽  
Giuseppe Serafino ◽  
...  
Keyword(s):  
Phospholipase D ◽  
Rare Case ◽  
Active Component ◽  
Clinical Course ◽  
Fatal Case ◽  
Skin Lesions ◽  
Systemic Effects ◽  
Spider Bites ◽  
Spider Bite ◽  
The Complement System

The spider bites are quite frequent and often resolve quickly without leaving outcomes; only some species are capable of causing necrotic and systematic lesions in humans. Among them, we should mention the genusLoxosceles. The venom released from the spider bite ofLoxoscelesspecies is composed of proteins, enzymes, and nonenzymatic polypeptides. The phospholipase D family was identified as the active component of the venom. This family of enzymes is responsible for the local and systemic effects observed in loxoscelism. Phospholipases D interact with cell membranes triggering alterations which involve the complement system and activation of neutrophils and they cause the dermonecrotic skin lesions and systemic effects. We describe a fatal case of acute intoxication caused by a spider bite probably belonging to the speciesLoxosceles. The initial lesion was localized to a finger of a hand. Clinical course was worsening with deep necrotic lesions on limb, shock, hemolysis, acute kidney failure, and disseminated intravascular coagulation. All therapies were ineffective. This is the first fatal case described in Europe.

Primary prostatic lymphoma: A rare case report

1995 ◽  
Vol 62 (1_suppl) ◽  
pp. 94-96 ◽  
Author(s):  
P. Tognoni ◽  
R. Banchero ◽  
U. Repetto ◽  
C. Caviglia ◽  
M. Cussotto ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Clinical Course ◽  
Rare Case Report

— We present a rare case report of a non-Hodgkin primary prostatic lymphoma. In the article we focus on the increasing number of primary urologic lymphomas, the usual indolent clinical course of such a neoplasm and the combination of surgery and chemotherapy that we performed in this case.

scholarly journals A rare case of Tetralogy of Fallot with right atrial thrombus presenting with hemiplegia complicating the clinical course

2021 ◽  
Author(s):  
Parag Sharma ◽  
Satyajit Samal ◽  
Debmalya Saha ◽  
Sayyed E. H. Naqvi ◽  
Saket Aggarwal ◽  
...  
Keyword(s):  
Tetralogy Of Fallot ◽  
Rare Case ◽  
Clinical Course ◽  
Right Atrial ◽  
Atrial Thrombus ◽  
Right Atrial Thrombus

scholarly journals Rare case of dermonecrosis caused by a recluse spider bite in Europe

2016 ◽  
pp. bcr2016215832 ◽  
Author(s):  
Monique Cachia ◽  
Liam Mercieca ◽  
Charles Mallia Azzopardi ◽  
Michael J Boffa
Keyword(s):  
Rare Case ◽  
Spider Bite

scholarly journals Leptospirosis presenting as severe cardiogenic shock: A case report

2018 ◽  
Vol 19 (4) ◽  
pp. 351-353
Author(s):  
E Forbat ◽  
MJ Rouhani ◽  
C Pavitt ◽  
S Patel ◽  
R Handslip ◽  
...  
Keyword(s):  
Case Report ◽  
Cardiogenic Shock ◽  
Social History ◽  
Rare Case ◽  
Clinical Course ◽  
Unknown Origin ◽  
Case Presentation ◽  
Pyrexia Of Unknown Origin ◽  
Severe Cardiogenic Shock ◽  
Infectious Illness

Background Leptospirosis is a rare infectious illness caused by the Spirochaete Leptospira. It has a wide-varying spectrum of presentation. We present a rare case of severe cardiogenic shock secondary to leptospirosis, in the absence of its common clinical features. Case presentation A 36-year-old woman presented to our unit with severe cardiogenic shock and subsequent multi-organ failure. Her clinical course was characterised by ongoing pyrexia of unknown origin with concurrent cardiac failure. She was initially managed with broad-spectrum antibiotics and inotropes. Percutaneous cardiac biopsy excluded major causes of myocarditis. On day 21 after presentation, she was found to be IgM-positive for leptospirosis. Conclusions This is a rare case of severe cardiogenic shock secondary to leptospirosis infection. The case also highlights the importance of obtaining a thorough social history when assessing a patient with an unusual presentation, as clues can often be missed.

scholarly journals Invasive aspergillosis with disseminated skin ınvolvement in a patient with acute myeloid leukemia: a rare case

2017 ◽  
Vol 9 (2) ◽  
Author(s):  
Duygu Mert ◽  
Gülşen Iskender ◽  
Fazilet Duygu ◽  
Alparslan Merdin ◽  
Mehmet Sinan Dal ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Invasive Aspergillosis ◽  
Myeloid Leukemia ◽  
Rare Case ◽  
Invasive Pulmonary Aspergillosis ◽  
Skin Lesions ◽  
Immunocompromised Patients ◽  
Skin Involvement ◽  
Pulmonary Aspergillosis ◽  
Acute Myeloid

Invasive pulmonary aspergillosis is most commonly seen in immunocompromised patients. Besides, skin lesions may also develop due to invasive aspergillosis in those patients. A 49-year-old male patient was diagnosed with acute myeloid leukemia. The patient developed bullous and zosteriform lesions on the skin after the 21st day of hospitalization. The skin biopsy showed hyphae. Disseminated skin aspergillosis was diagnosed to the patient. Voricanazole treatment was initiated. The patient was discharged once the lesions started to disappear.

Arterial Thrombosis and Gangrene Secondary to Arachnidism

Vascular ◽  
2009 ◽  
Vol 17 (4) ◽  
pp. 239-242
Author(s):  
Jan M. Eckermann ◽  
Theodore H. Teruya ◽  
Christian Bianchi ◽  
Ahmed M. Abou-Zamzam
Keyword(s):  
Case Report ◽  
Lower Extremity ◽  
Vascular Disease ◽  
Tissue Damage ◽  
Arterial Thrombosis ◽  
Progressive Necrosis ◽  
Life Threatening ◽  
History Of ◽  
Spider Bites ◽  
Spider Bite

Spider bites can cause local tissue damage as well as life-threatening complications. This is a case report of a female with no history of lower extremity vascular disease who presented with a spider bite on the dorsum of her foot. She developed progressive necrosis and eventually suffered limb loss despite attempts at revascularization.

A two year study of verified spider bites in Switzerland and a review of the European spider bite literature

Toxicon ◽  
2013 ◽  
Vol 73 ◽  
pp. 104-110 ◽  
Author(s):  
Wolfgang Nentwig ◽  
Markus Gnädinger ◽  
Joan Fuchs ◽  
Alessandro Ceschi
Keyword(s):  
Spider Bites ◽  
Spider Bite

scholarly journals Effect of Genetic and Laboratory Findings on Clinical Course of Antisynthetase Syndrome in a Hungarian Cohort

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Katalin Szabó ◽  
Levente Bodoki ◽  
Melinda Nagy-Vincze ◽  
Anett Vincze ◽  
Erika Zilahi ◽  
...  
Keyword(s):  
Prognostic Markers ◽  
Clinical Course ◽  
Disease Onset ◽  
Skin Lesions ◽  
Clinical Database ◽  
Laboratory Findings ◽  
Disease Phenotypes ◽  
Genetic Features ◽  
Hla Dqa1

The aim of this study was to determine the clinical, serological, and genetic features of anti-Jo-1 positive antisynthetase patients followed by a Hungarian single centre to identify prognostic markers, which can predict disease phenotypes and disease progression. It was a retrospective study using clinical database of 49 anti-Jo-1 positive patients. 100% of patients exhibited myositis, 73% interstitial lung disease, 88% arthritis, 65% Raynaud’s phenomenon, 43% fever, 33% mechanic’s hand, and 12% dysphagia. We could detect significant correlation between anti-Jo-1 titer and the CK and CRP levels at disease onset and during disease course. HLA DRB1⁎03 positivity was present in 68.96% of patients, where the CK level at diagnosis was significantly lower compared to the HLA DRB1⁎03 negative patients. HLA DQA1⁎0501-DQB1⁎0201 haplotype was found in 58.62% of patients, but no significant correlation was found regarding any clinical or laboratory features. Higher CRP, ESR level, RF positivity, and the presence of fever or vasculitic skin lesions at the time of diagnosis indicated a higher steroid demand and the administration of higher number of immunosuppressants during the follow-up within anti-Jo-1 positive patients. The organ involvement of the disease was not different in HLA-DRB1⁎0301 positive or negative patients who were positive to the anti-Jo-1 antibody; however, initial CK level was lower in HLA-DRB1⁎0301 positive patients. Distinct laboratory and clinical parameters at diagnosis could be considered as prognostic markers.

scholarly journals A Case of Rupioid Syphilis Masquerading as Aggressive Cutaneous Lymphoma

2015 ◽  
Vol 7 ◽  
pp. e2015026 ◽  
Author(s):  
Jonathan Braue ◽  
Thomas Hagele ◽  
Abraham Tareq Yacoub ◽  
Suganya Mannivanan ◽  
Frank Glass ◽  
...  
Keyword(s):  
19Th Century ◽  
Immune Reconstitution Inflammatory Syndrome ◽  
Immune Reconstitution ◽  
Rare Case ◽  
Skin Lesions ◽  
Secondary Syphilis ◽  
Cutaneous Lymphoma ◽  
Hiv Positive ◽  
Late 19Th Century ◽  
Inflammatory Syndrome

Secondary syphilis has been known since the late 19th century as the great imitator; however, some experts now regard cutaneous lymphoma as the great imitator of skin disease. Either disease, at times an equally fastidious diagnosis, has reported to even mimic each other. It is thus vital to consider these possibilities when presented with a patient demonstrating peculiar skin lesions. No other manifestation of secondary syphilis may pose such quandary as a rare case of rupioid syphilis impersonating cutaneous lymphoma. We present such a case, of a 36-year-old HIV positive male, misdiagnosed with aggressive cutaneous lymphoma, actually exhibiting rupioid syphilis thought secondary to immune reconstitution inflammatory syndrome (IRIS).

scholarly journals Iatrogenic Teratoma Rupture during TVOR Complicated with Peritonitis, Pleuritis, and Septic Shock

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Pei-Yi Wang ◽  
Yi-En Chang ◽  
Yu-Chieh Lee ◽  
Chii Ruey Tzeng
Keyword(s):  
Septic Shock ◽  
Surgical Treatment ◽  
Rare Case ◽  
Clinical Course ◽  
Oocyte Retrieval ◽  
Chemical Irritation ◽  
Chemical Peritonitis ◽  
Purulent Fluid ◽  
Exploratory Laparoscopy ◽  
Transvaginal Oocyte Retrieval

Objective. To obtain a better understanding of the clinical course and the subsequent complications of teratoma rupture. Case. We report a rare case of chemical peritonitis and pleuritis caused by teratoma rupture during ultrasonographically guided transvaginal oocyte retrieval (TVOR). The patient initially presented with nonspecific and digestive symptoms after TVOR, but the condition deteriorated rapidly after three weeks with peritonitis and septic shock. Thus, exploratory laparoscopy was performed with the findings of a ruptured teratoma at left adnexa, severe adhesions, and purulent fluid in her peritoneal cavity. Bilateral pleuritis was also noted after the operation, which was suspected to be caused by chemical irritation of the spilled contents of the teratoma. The patient’s condition improved after surgical treatment and was discharged 28 days after admission. Conclusion. Our case showed that the timing of peritoneal irritation caused by teratoma rupture converting to severe chemical peritonitis was approximately 3 weeks. Physicians should avoid cyst puncture during TVOR and closely observe or even perform surgical treatment when iatrogenic teratoma ruptures are suspected.

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