scholarly journals Dyspepsia: When and How to Test forHelicobacter pyloriInfection

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Maria Pina Dore ◽  
Giovanni Mario Pes ◽  
Gabrio Bassotti ◽  
Paolo Usai-Satta
Keyword(s):  
Primary Care ◽  
Functional Dyspepsia ◽  
Primary Care Physicians ◽  
Epigastric Pain ◽  
Noninvasive Testing ◽  
Medication History ◽  
Breath Testing ◽  
Rome Iii ◽  
History Of ◽  
H Pylori

Dyspepsia is defined as symptoms related to the upper gastrointestinal tract. Approximately 25% of western populations complain of dyspeptic symptoms each year. 70% of them do not have an organic cause and symptoms are related to the so-called functional dyspepsia, characterized by epigastric pain, early satiety, and/or fullness during or after a meal occurring at least weekly and for at least 6 months according to ROME III criteria. In order to avoid invasive procedures and adverse effects, to minimize costs, to speed up diagnosis, and to provide the most appropriate treatments, primary care physicians need to recognize functional dyspepsia. Because symptoms do not reliably discriminate between organic and functional forms of the disease, anamnesis, family history of peptic ulcer and/or of gastric cancer, medication history, especially for nonsteroidal anti-inflammatory drugs, age, and physical examination could help the physician in discerning between functional dyspepsia and organic causes. For patients without alarm symptoms, noninvasive testing forH. pylori, with either carbon-13-labeled urea breath testing or stool antigen testing, is recommended as a first-line strategy. In this review, we provide recommendations to guide primary care physicians for appropriate use of diagnostic tests and forH. pylorimanagement in dyspeptic patients.

scholarly journals HELICOBACTER PYLORI

2018 ◽  
Vol 21 (04) ◽  
pp. 679-683
Author(s):  
Shuaib Ansari ◽  
Irfan Murtaza Shahwani ◽  
Aqeel Ahmed Channa ◽  
Syed Zulfiquar Ali Shah ◽  
Tarachand Devrajani
Keyword(s):  
Functional Dyspepsia ◽  
Histopathological Examination ◽  
Epigastric Pain ◽  
P Value ◽  
Male Population ◽  
Low Socioeconomic ◽  
Multidisciplinary Study ◽  
History Of ◽  
The Mean ◽  
H Pylori

Objective: To determine the frequency of H. pylori in patients with functionaldyspepsia. Patients and methods: This six months multidisciplinary study was conducted attertiary care teaching hospital as well as at private hospital Hyderabad from February 2012 to July2012. All patients presented with history of dyspepsia were admitted and evaluated for functionaldyspepsia by performing endoscopy. After confirmation of functional dyspepsia the subjectswere further evaluated for H. pylori infection by taking the biopsy specimen, label it and sent tolaboratory for histopathological examination. The data was entered, saved and analyzed in SPSSversion 11.00. Results: During six month study period, total 100 patients with functionaldyspepsia were recruited. Majority of patients were from low socioeconomic class (78%), havehistory of spicy food intake (68%) and epigastric pain (94%). The associated symptoms observedwere nausea and vomiting (87%), anorexia (88%), early satiety (84%) and regurgitation (84%).The mean ±SD for age of patients with functional dyspepsia was 37.95±10.85. The mean age±SD of H. pylori identified patients was 35.81±7.72. Majority of the subjects was 30-40 years ofage and the male population predominant 64% (p-value 0.02, statistically significant). The H.pylori was identified in 62% of patients, of which 35 (56.5%) were males and 27(43.5%) werefemales (p-value 0.04, statistically significant) respectively.

scholarly journals The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia

2019 ◽  
Vol 9 (2) ◽  
pp. 321-324 ◽  
Author(s):  
Vahideh Ebrahimzadeh Attari ◽  
Mohammad Hosein Somi ◽  
Mohammad Asghari Jafarabadi ◽  
Alireza Ostadrahimi ◽  
Seyed-Yaghob Moaddab ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Helicobacter Pylori ◽  
Functional Dyspepsia ◽  
Zingiber Officinale ◽  
Complementary Therapy ◽  
Positive Functional ◽  
Before And After ◽  
Rome Iii ◽  
Ginger Powder ◽  
H Pylori

Purpose: The present study aimed to assess the effect of ginger (Zingiber officinale) powder supplementation on Helicobacter pylori eradication and improvement of dyspeptic symptoms in patients with H. pylori positive functional dyspepsia (FD). Methods: During this pilot study 15 patients with H. pylori positive FD received 3 g/d ginger powder as three 1-g tablets for 4-weeks. Dyspepsia symptoms were asked before and after the intervention using a questionnaire based on the Rome III criteria. H. pylori eradication was also assessed by a non-invasive stool antigen (HpSAg) test. Results: Ginger consumption accompanied by significant H. pylori eradication rate of 53.3% (P = 0.019) and the odds ratio (95% CI) was 8 (1.07 to 357.14). Moreover, our results showed significant changes in most of the dyspepsia symptoms after ginger supplementation. Conclusion: According to our findings, Z. officinale can be considered as a useful complementary therapy for FD. However, due to the small number of clinical trials in this area, further welldesigned clinical trials are needed to explicitly talk about its effectiveness especially about the eradication of H. pylori.

scholarly journals UNDERSTANDING OSTEOPOROSIS SCREENING PRACTICES IN MEN: A NATIONWIDE PHYSICIAN SURVEY

2020 ◽  
Vol 26 (11) ◽  
pp. 1237-1243
Author(s):  
Palak Choksi ◽  
Brittany L. Gay ◽  
David Reyes-Gastelum ◽  
Megan R. Haymart ◽  
Maria Papaleontiou
Keyword(s):  
Primary Care ◽  
Confidence Interval ◽  
Primary Care Physicians ◽  
Menopausal Woman ◽  
Significant Past Medical History ◽  
Endocrine Society ◽  
Osteoporosis Screening ◽  
Screening Practices ◽  
Clinical Scenarios ◽  
History Of

Objective: To understand osteoporosis screening practices, particularly in men, by a diverse cohort of physicians, including primary care physicians, endocrinologists, and geriatricians. Methods: We surveyed randomly selected members of the American Academy of Family Practice, Endocrine Society, and American Geriatrics Society. Respondents were asked to rate how often they would screen for osteoporosis in four different clinical scenarios by ordering a bone density scan. Multivariable logistic regression analyses were conducted to determine factors associated with offering osteoporosis screening in men in each clinical scenario. Physicians were also asked to note factors that would lead to osteoporosis screening in men. Results: Response rate was 63% (359/566). While 90% respondents reported that they would always or frequently screen for osteoporosis in a 65-year-old post-menopausal woman, only 22% reported they would screen a 74-year-old man with no significant past medical history. Endocrinologists were more likely to screen a 74-year-old man compared to primary care physicians (odds ratio, 2.32; 95% confidence interval, 1.10 to 4.88). In addition to chronic steroid use (94%), history of nontraumatic fractures (88%), and androgen-deprivation therapy for prostate cancer (82%), more than half the physicians reported suppressive doses of thyroid hormone (64%) and history of falls (52%) as factors leading to screening for osteoporosis in men. Conclusion: Our survey results highlight heterogeneity in osteoporosis screening in men, with underscreening in some scenarios compared to women, and identify factors that lead to screening in men. These findings can help design interventions to improve osteoporosis screening in men. Abbreviation: CI = confidence interval

scholarly journals Development of a prediction model to aid primary care physicians in early identification of women at high risk of developing endometriosis: cross-sectional study

BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e030346
Author(s):  
Nina Julie Verket ◽  
Ragnhild Sørum Falk ◽  
Erik Qvigstad ◽  
Tom Gunnar Tanbo ◽  
Leiv Sandvik
Keyword(s):  
Primary Care ◽  
Family History ◽  
High Risk ◽  
Prediction Model ◽  
Early Identification ◽  
Primary Care Physicians ◽  
Lasso Regression ◽  
Cross Sectional ◽  
Predictive Values ◽  
History Of

ObjectivesTo identify predictors of disease among a few factors commonly associated with endometriosis and if successful, to combine these to develop a prediction model to aid primary care physicians in early identification of women at high risk of developing endometriosis.DesignCross-sectional anonymous postal questionnaire study.SettingWomen aged 18–45 years recruited from the Norwegian Endometriosis Association and a random sample of women residing in Oslo, Norway.Participants157 women with and 156 women without endometriosis.Main outcome measuresLogistic and least absolute shrinkage and selection operator (LASSO) regression analyses were performed with endometriosis as dependent variable. Predictors were identified and combined to develop a prediction model. The predictive ability of the model was evaluated by calculating the area under the receiver operating characteristic curve (AUC) and positive predictive values (PPVs) and negative predictive values (NPVs). To take into account the likelihood of skewed representativeness of the patient sample towards high symptom burden, we considered the hypothetical prevalences of endometriosis in the general population 0.1%, 0.5%, 1% and 2%.ResultsThe predictors absenteeism from school due to dysmenorrhea and family history of endometriosis demonstrated the strongest association with disease. The model based on logistic regression (AUC 0.83) included these two predictors only, while the model based on LASSO regression (AUC 0.85) included two more: severe dysmenorrhea in adolescence and use of painkillers due to dysmenorrhea in adolescence. For the prevalences 0.1%, 0.5%, 1% and 2%, both models ascertained endometriosis with PPV equal to 2.0%, 9.4%, 17.2% and 29.6%, respectively. NPV was at least 98% for all values considered.ConclusionsExternal validation is needed before model implementation. Meanwhile, endometriosis should be considered a differential diagnosis in women with frequent absenteeism from school or work due to painful menstruations and positive family history of endometriosis.

scholarly journals Prevalence of functional dyspepsia in an outpatient clinic with primary care physicians in Japan

2009 ◽  
Vol 45 (2) ◽  
pp. 187-194 ◽  
Author(s):  
Toshikatsu Okumura ◽  
Sachie Tanno ◽  
Masumi Ohhira ◽  
Satoshi Tanno
Keyword(s):  
Primary Care ◽  
Functional Dyspepsia ◽  
Outpatient Clinic ◽  
Primary Care Physicians

scholarly journals Physical Manipulation-Induced Femoral Neck Fracture: A Case Report

2020 ◽  
pp. 118-122
Author(s):  
Rami A. Ayoubi ◽  
Nour S. Nassour ◽  
Elias G. Saidy ◽  
Dany K. Aouad ◽  
Joseph S. Maalouly ◽  
...  
Keyword(s):  
Primary Care ◽  
Hip Fracture ◽  
Primary Care Physicians ◽  
Treatment Modalities ◽  
Cerebrovascular Accidents ◽  
Neck Fracture ◽  
History Of ◽  
Hemi Arthroplasty ◽  
History Of Parkinson’S Disease ◽  
Physical Manipulation

Manipulative treatments for pain are very widely used nowadays by a variety of physicians. These treatment modalities are generally safe, but various studies have reported serious complications. This report presents the case of a 78-year-old male patient with a history of Parkinson’s disease, who was diagnosed with a right hip fracture that occurred as a result of physical manipulative treatment. He underwent a cemented hemi-arthroplasty as appropriate surgical treatment of his condition. Manipulative treatments can result in minor and major complications ranging from simple sprains and rib fractures to cerebrovascular accidents and death. The frequency of these events seems to be rare; however, no robust studies are present and further investigations are urgently needed. Hip fractures as a result of this treatment have not been previously mentioned. This is the first reported case in the literature of a hip fracture resulting from manipulative treatment. Primary care physicians and orthopedists should be aware of the possibility of this outcome and rule it out whenever necessary.

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