Necrotizing Sialometaplasia of the Hard Palate in a Patient Treated with Topical Nonsteroidal Anti-Inflammatory Drug

Necrotizing sialometaplasia is a rare, benign, self-limiting, necrotizing process involving the minor salivary glands, mainly the mucoserous glands of the hard palate. It is thought to be the result of an ischemic event of the vasculature supplying the salivary gland lobules. Some predisposing factors such as smoking, use of alcohol, denture wearing, recent surgery, traumatic injuries, respiratory infections, systemic diseases bulimia, and anorexia have been described. Herein we present a case of necrotizing sialometaplasia of the hard palate in a patient without known predisposing factors, in our opinion, resulting from the use of topical anti-inflammatory drug. After diagnosis, the patient underwent treatment with chlorhexidine gluconate and a full palatal acrylic guard to protect the exposed bone from food residues during meals. After the sixth week the lesion regressed.

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Treatment of the Temporomandibular Joint Arthritis

Journal of Diagnostics and Treatment of Oral and Maxillofacial Pathology ◽

10.23999/j.dtomp.2021.9.5 ◽

2021 ◽

Vol 5 (9) ◽

pp. 112-114

Author(s):

Oleksii Tymofieiev ◽

Diana Havlytiuk ◽

Viktoriia Ripa ◽

Marta Sokoliuk ◽

Lesia Kolisnichenko

Keyword(s):

Temporomandibular Joint ◽

Respiratory Infections ◽

Allergic Diseases ◽

Inflammatory Drug ◽

Aged People ◽

Temporomandibular Joints ◽

Inflammatory Processes ◽

Post Traumatic ◽

Anti Inflammatory ◽

Traumatic Arthritis

Temporomandibular joint (TMJ) arthritis is an inflammatory process in the TMJ. It`s more common in young and middle-aged people. Among the reasons of the TMJ arthritis development may be the following: local infection (periodontal disease, gingivitis, stomatitis, otitis, tonsillitis, osteomyelitis of the jaw, etc.), general infectious diseases (acute respiratory infections, influenza, pneumonia, dysentery, tuberculosis, syphilis, etc.), allergic diseases, traumatic effects, etc. Para-allergic factors contribute to the onset of TMJ inflammatory processes (hypothermia, overheating, etc.), changes in the endocrine and nervous systems, foci of chronic infection (especially in the oral cavity), etc. The purpose of this pare is to determine the effectiveness of the use of the non-steroidal anti-inflammatory drug “Nimesil” in the complex treatment of acute arthritis of the TMJ. We observed 64 patients in age from 24 to 65 years who were diagnosed with acute post-traumatic arthritis of the TMJ. Patients were divided into 2 observation groups: 1st group (the main one) – 31 patients who were treated with the nonsteroidal anti-inflammatory drug “Nimesil” and 2nd group (the control one) – 33 patients who were prescribed treatment, including the use of a nonsteroidal anti-inflammatory drug “Indomethacin.” The duration of the treatment was 7-8 days. After the relieving of acute inflammation, according to indications, prosthetic treatment was carried out. Treatment was carried out in 64 patients with acute post-traumatic arthritis of the temporomandibular joints by comparative use of various non-steroidal anti-inflammatory drugs in different observation groups. It has been proved that the drug “Nimesil” has a more expressed analgesic, antiinflammatory and antipyretic effect, and also has a significantly smaller number of side effects compared to the drug “Indomethacin.”

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