scholarly journals Estimation of Antioxidant Levels in Saliva and Serum of Chronic Periodontitis Patients with and without Ischemic Heart Disease

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Anahita Punj ◽  
Santhosh Shenoy ◽  
N. Suchetha Kumari ◽  
Priyanka Pampani
Keyword(s):  
Superoxide Dismutase ◽  
Heart Disease ◽  
Glutathione Peroxidase ◽  
Ischemic Heart Disease ◽  
Antioxidant Capacity ◽  
Chronic Periodontitis ◽  
Ischemic Heart ◽  
Healthy Controls ◽  
Total Antioxidant ◽  
The Mean

Objective. To investigate whether there is a relationship between periodontitis and ischemic heart disease by estimation of total antioxidant status in saliva and serum. Materials and Methods. A total of 80 samples were collected and divided equally into 4 groups of healthy controls, chronic periodontitis patients, ischemic heart disease patients with periodontitis, and ischemic heart disease patients without periodontitis. Saliva and venous blood samples were collected and analyzed for levels of total antioxidant capacity, superoxide dismutase, glutathione peroxidase, and catalase. Results. There were significant (p<0.05) differences in the mean serum levels of total antioxidant capacity (p<0.001), superoxide dismutase (p<0.001), glutathione peroxidase (p<0.006), and catalase (p<0.001) within the 4 groups, whereas the mean salivary levels were significant only for glutathione peroxidase (p=0.001). Both of these serum and salivary antioxidant levels were lower in disease groups of IHD + CP, IHD + H, and CP as compared to healthy controls, with different patterns. Conclusion. Antioxidant capacity is significantly hampered in chronic periodontitis and ischemic heart disease patients with or without periodontitis as compared to healthy controls. The salivary and serum antioxidants may not follow the same increase or decrease as a result of increased oxidant stress due to disease.

scholarly journals Hospitalization Expenses and Influencing Factors for Inpatients with Ischemic Heart Disease in Iran: A Retrospective Study

Health Scope ◽  
2022 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Maryam Shirvani Shiri ◽  
Sara Emamgholipour ◽  
Rajabali Daroudi ◽  
Maryam Tatary ◽  
Zohreh Kazemi ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Influencing Factors ◽  
Financial Burden ◽  
First Grade ◽  
Ischemic Heart ◽  
Icu Admission ◽  
Medical Supplies ◽  
Hospitalization Costs ◽  
The Mean

Background: Ischemic heart disease (IHD) is the leading cause of death and disability worldwide and in Iran, which imposes a heavy financial burden both on patient’s family and society. Objectives: This study aimed to analyze the direct medical costs of inpatients with IHD and its influencing factors in Iran in 2020. Methods: The sample of this cross-sectional study included 41,357 patients with IHD selected from the hospital information system (HIS) of the Iran Health Insurance Organization from August 23, 2019, to June 20, 2020. The study used the claims data of these patients, which included their demographics, length of stay (LOS), intensive care unit (ICU) admission, hospital accreditation grade, hospital ownership type, and patient discharge status. The multiple linear regression model was employed to evaluate the relationship between hospitalization costs and the associated factors. All statistical tests were conducted at the significance level of P < 0.05 using the R 3.6.3 software. Results: The mean age of patients was 63.95 ± 12.63 years old, and most of them were male (54.4%). The mean hospitalization cost per patient and per day was 586.42 ± 472.51 USD and 103.64 ± 100.29 USD, respectively. Moreover, the mean LOS was 4.92 days. Drugs and consumable medical supplies, as well as nursing and hoteling services, had the highest shares of hospitalization costs (29.54% and 29.4%, respectively). The hospitalization costs of patients with IHD were higher among men (β = 1.24), age 61 - 70 years (β = 1.38), LOS ≥ 5 (β = 2.92), ICU admission (β = 1.62), Iranian health fund (β = 1.21), and private hospitals (β = 1.91). Top-grade and first-grade hospitals had higher costs compared to grade 2 (β = 0.67), grade 3 (β = 0.35), and grade 4 (β = 0.72) hospitals. Deceased patients had also higher costs than patients with complete recovery (β = 0.63), relative recovery (β = 0.59), follow-up (β = 0.51), transfer to other medical centers (β = 0.44), and discharge against medical advice (DAMA) (β = 0.62). Conclusions: According to the results, shortening the LOS and controlling the high costs of drugs and consumable medical supplies are among the main strategies to reduce high hospitalization costs.

scholarly journals Increased risk of ischemic heart disease after kidney donation

2021 ◽  
Author(s):  
Anders J Haugen ◽  
Stein Hallan ◽  
Nina E Langberg ◽  
Dag Olav Dahle ◽  
Hege Pihlstrøm ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Cerebrovascular Disease ◽  
Ischemic Heart ◽  
Kidney Donation ◽  
Baseline Body Mass Index ◽  
Healthy Controls ◽  
Kidney Donors ◽  
Increased Risk

Abstract Background Previous reports suggest increased risk of hypertension and cardiovascular mortality after kidney donation. In this study we investigate occurrence of ischemic heart disease and cerebrovascular disease, diabetes and cancer in live kidney donors compared with healthy controls eligible for donation. Methods Different diagnoses were assessed in 1029 kidney donors and 16084 controls. The diagnoses at follow-up were self-reported for the controls and registered by a physician for the donors. Stratified logistic regression was used to estimate associations with various disease outcomes, adjusted for gender, age at follow up, smoking at baseline, body mass index at baseline, systolic blood pressure at baseline and time since donation. Results The mean (standard deviation) observation time was 11.3 (8.1) years for donors versus 16.4 (5.7) years for controls. Age at follow-up was 56.1 (12.4) years in donors vs 53.5 (11.1) years in controls and 44% of donors were males vs 39.3% in the controls. At follow up 35 (3.5%) of the donors had been diagnosed with ischemic heart disease versus 267 (1.7%) of the controls. Adjusted odds ratio for ischemic heart disease was 1.64 (confidence interval 1.10-2.43, P = 0.01) in donors compared with controls. There were no significant differences for the risks of cerebrovascular disease, diabetes or cancer. Conclusions During long-term follow-up of kidney donors we find an increased risk of ischemic heart disease compared to healthy controls. This information may be important in the follow-up and selection process of living kidney donors.

scholarly journals Plasma and salivary total antioxidant capacity in healthy controls compared with aggressive and chronic periodontitis patients

2015 ◽  
Vol 36 (7) ◽  
pp. 856-861 ◽  
Author(s):  
Ulku Baser ◽  
Hikmet Gamsiz-Isik ◽  
Emine Cifcibasi ◽  
Evin Ademoglu ◽  
Funda Yalcin
Keyword(s):  
Antioxidant Capacity ◽  
Chronic Periodontitis ◽  
Total Antioxidant Capacity ◽  
Healthy Controls ◽  
Total Antioxidant

scholarly journals Lipid peroxidation and glutathione peroxidase in ischemic heart disease

2001 ◽  
Vol 16 (2) ◽  
pp. 213-215 ◽  
Author(s):  
K. S. Motghare ◽  
Anil Bhutey ◽  
B. B. Murrhar ◽  
Madhur Gupta ◽  
A. W. Meshram ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Heart Disease ◽  
Glutathione Peroxidase ◽  
Ischemic Heart Disease ◽  
Ischemic Heart

scholarly journals Antioxidative responses to seasonal changes and chemiluminescence assay of Astragalus onobrychis leaves extract

2013 ◽  
Vol 11 (2) ◽  
pp. 123-132
Author(s):  
Dragoljub Miladinović ◽  
Budimir Ilić ◽  
Stevo Najman ◽  
Olga Cvetković ◽  
Aleksandra Šajnović ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Enzyme Activity ◽  
Glutathione Peroxidase ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Seasonal Changes ◽  
Antioxidant Enzyme Activity ◽  
Guaiacol Peroxidase ◽  
Stages Of Growth ◽  
Total Antioxidant

AbstractThe aim of this study was to research the seasonal changes of antioxidant enzyme activity and total antioxidant capacity in leaves of Astragalus onobrychis L. subsp. chlorocarpus (Griseb.) S. Kozuharov et D.K. Pavlova. Leaves of A. onobrychis were collected during the different stages of growth and analyzed for antioxidant enzyme activity: superoxide dismutase, catalase, guaiacol peroxidase, glutathione peroxidase. Quantities of malonyldialdehyde, superoxide radicals, and hydroxyl radicals were measured as well as the content of soluble proteins. Furthermore, total antioxidant capacity was determined by the inhibition of chemiluminescence activity of blood phagocytes by leaf extracts. Stages of vegetation significantly affected the accumulation of superoxide radicals, but there were no significant differences in hydroxyl radical quantity and lipid peroxidation levels during vegetation. Soluble proteins vary greatly between different stages of growth. Seasonal changes were found to have an effect on enzymatic activities. During the spring season, guaiacol peroxidase showed the highest levels. Catalase and glutathione peroxidase increased their activities in summer, while, during the autumn season, superoxide dismutase showed maximum activity. On the basis of chemiluminescence assay, it can be concluded that leaf extract of A. onobrychis possesses a significant antioxidant capacity thus protecting plants during environmental stress.

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