scholarly journals Low-Grade Mucoepidermoid Carcinoma of the Lacrimal Gland in a Teenaged Patient

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Ozgun Melike Gedar Totuk ◽  
Mustafa Kemal Demir ◽  
Ozlem Yapicier ◽  
Mert Mestanoglu

Mucoepidermoid carcinoma is the most common malignant, locally invasive tumour of the salivary glands and accounts for approximately 35% of all malignancies of the major and minor salivary glands. Mucoepidermoid carcinoma that originated from the lacrimal gland is exceedingly rare in teenage patients, with only a few cases reported. Herein, we report clinical and radiological findings of a mucoepidermoid carcinoma arising from the lacrimal gland in a 15-year-old boy. We suggest that since preoperative imaging findings are not diagnostic for mucoepidermoid carcinoma, histopathologic examination should be performed for definitive diagnosis. Complete surgical resection is the treatment of choice for low-grade lacrimal gland mucoepidermoid carcinoma.

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Rammohan Kumar ◽  
Srikant Natarajan ◽  
K.S. Sneha ◽  
Nunna Sai Chitra ◽  
Karen Boaz ◽  
...  

The origin of a salivary gland tumour is attributed to cells at various levels of differentiation which present histologically as diverse tissues and cellular patterns. Mitochondria-rich, eosinophilic oncocytes are cells commonly encountered in salivary gland neoplasms. We report a case of mucoepidermoid carcinoma (MEC) in the palate of a 43-year-old female that exhibited a prominent oncocytic component. While the parotid and submandibular glands have been reported as predominant sites for oncocytic MEC (OMEC), the palate and minor salivary glands are rare sites for occurrence. Also, most of the reported cases of OMEC have been histologically of low-grade mucoepidermoid carcinoma with large cystic spaces and good prognosis. In this article, we discuss the differential diagnosis and diagnostic workup of an MEC presenting with oncocytes.


2019 ◽  
pp. 1-3
Author(s):  
Andrew C. Jenzer ◽  
James P. Arnold ◽  
Christopher J. Smith ◽  
Keith D. Jackson

Necrotizing sialometaplasia (NS) is a rare condition which can be easily confused with malignancy. Its presentation initially parallels mucoepidermoid carcinoma or squamous cell carcinoma, however, NS is a benign, self-limiting inflammatory disease of the mucus-secreting minor salivary glands. NS is thought to be caused by trauma which induces vascular ischemia of these minor salivary glands. Diagnosing NS continues to be difficult, and clinical history remains one of the pillars of ruling out cancer. This report details a case of NS in a 37-year-old male who presented to the Womack Army Medical Center Oral and Maxillofacial Surgery Clinic with an exophytic mass in his right-hand palate. He had a history of recent trauma induced to the area via incision and drainage to address what was believed to be a palatal space infection. Later, an incisional biopsy was performed after the exophytic mass persisted. The initial local pathology report favored low-grade mucoepidermoid carcinoma, but after review by the Joint Pathology Center at Walter Reed Military Medical Center, the consensus diagnosis was established as NS. The patient returned to the clinic five weeks later with the exophytic mass no longer present and the biopsy site healing well.


Author(s):  
GIOVANNA PEREIRA DE SOUZA ◽  
CARLOS EDUARDO DE OLIVEIRA ◽  
WILSON DÉDA GONÇALVES JÚNIOR ◽  
JOHN LENNON SILVA CUNHA ◽  
MARIA DE FÁTIMA BATISTA MELO ◽  
...  

2016 ◽  
Vol 77 (04) ◽  
pp. e156-e159 ◽  
Author(s):  
Rimal Dossani ◽  
Hesam Akbarian-Tefaghi ◽  
Lori Lemonnier ◽  
Vikas Mehta ◽  
Jamie Jacobsohn ◽  
...  

1995 ◽  
Vol 109 (5) ◽  
pp. 466-468 ◽  
Author(s):  
Bonnie L. Kemp ◽  
John G. Batsakis ◽  
Adel K. El-Naggar ◽  
Sophia N. Kotliar ◽  
Mario A. Luna

AbstractThe major salivary glands are considered to rarely be the sites of primary terminal duct adenocarcinomas, a neoplasm with a considerable predilection for origin from intraoral minor salivary glands. We present a clinicopathological study of 22 terminal duct adenocarcinomas of the parotid gland, the largest single series to date. A comparison between the parotid neoplasms and over 200 minor salivary gland terminal duct adenocarcinomas indicates there is little difference in biological behaviour and confirms the low-grade quality of the carcinomas, regardless of site of origin.


2019 ◽  
Vol 10 ◽  
pp. 215265671988903 ◽  
Author(s):  
Madison J. Malfitano ◽  
Meghan N. Norris ◽  
Wesley H. Stepp ◽  
Griffin D. Santarelli ◽  
T. Danielle Samulski ◽  
...  

Background Hyalinizing clear cell carcinomas (HCCCs) are rare, low-grade, malignant tumors which most often arise from the minor salivary glands primarily in palate and tongue but can arise in any location with minor salivary glands including the nasopharynx. Methods A case report of primary nasopharyngeal HCCC is presented. Because of the rarity of this tumor and location, a literature search was conducted to determine the most common presenting symptoms, treatment strategies, and outcomes. Results A 48-year-old man underwent biopsy of a 4.5 cm mass of the right nasopharynx with pathology suggesting an intermediate grade mucoepidermoid carcinoma. After discussing management with the patient, an endoscopic resection was performed. Final pathology revealed an HCCC which was confirmed after negative Mastermind-like 2 (MAML2) and positive Ewing sarcoma breakpoint region 1 (ESWR1) gene rearrangements on fluorescence in situ hybridization (FISH) studies. Literature review of other nasopharyngeal HCCC cases shows diverse presentation and overall excellent prognosis through surgical and radiation therapy. Conclusion HCCCs are rare, low-grade malignant tumors of the minor salivary glands and can present as a nasopharyngeal mass. Presenting symptoms are diverse but frequently involve otologic and sinonasal disturbances. HCCC is an indolent tumor with an excellent prognostic outcome when treated appropriately with surgical resection and adjuvant radiotherapy.


2020 ◽  
Vol 13 (10) ◽  
pp. e235932
Author(s):  
Sofia Dutra ◽  
Miguel Rito ◽  
Miguel Vilares ◽  
Alexandra Borges

Mucinous cystadenocarcinoma of minor salivary glands is an extremely rare entity that has only recently been described, with a few published cases in the English literature. A 42-year-old woman with a history of a surgically excised mucinous cystadenoma of the oral tongue, presented with a painful swelling in the oral tongue slowly growing for 1 month. On clinical examination, there was a firm, relatively well-circumscribed mass in the left posterior border of the mobile tongue. Subsequent MRI scan revealed a heterogeneous lesion composed of multiple cysts separated by contrast enhancing septa, in the posterior two-thirds of the left tongue. Imaging findings were similar to those of the previously resected mass, suggesting local relapse of the primary lesion. A complete surgical excision was performed and the histopathological examination revealed typical features of a low-grade mucinous cystadenocarcinoma of minor salivary glands.


2011 ◽  
Author(s):  
Frederico O. Gleber-Netto ◽  
Taynara Nunes Guedes Florencio ◽  
Silvia Ferreira Sousa ◽  
Elismauro Francisco Mendonça ◽  
Carolina Cavalieri Gomes ◽  
...  

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