scholarly journals Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Ayodele Jacob Akinyemi ◽  
Philip Adeyemi Adeniyi
Keyword(s):  
Prefrontal Cortex ◽  
Essential Oil ◽  
Essential Oils ◽  
Neurological Diseases ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Inflammatory Biomarkers ◽  
Tnf Alpha ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric rhizomes on some cytokines in cadmium induced neurotoxicity. The result revealed that essential oil from ginger and turmeric rhizomes exerts anti-inflammatory effect by preventing alterations of some cytokines/inflammatory biomarkers (IL-6, IL-10 and TNF-Alpha) levels and inhibits both hippocampus and prefrontal cortex acetylcholinesterase (AChE) and adenosine deaminase (ADA) activities (important enzymes relevant in the management/prevention of neurodegenerative diseases) in Cd treated rats. In conclusion, essential oil from ginger and turmeric rhizomes exerts anti-inflammatory properties in Cd induced neurotoxicity. The observed effect could be due to the volatile compounds as revealed by GC-MS analysis.

Anti-inflammatory effect of Curcuma longa (turmeric) rhizome when administered topically in gel form

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
AH Mollik ◽  
W Mozammel Haq ◽  
S Chandra Bachar ◽  
R Jahan ◽  
M Rahmatullah
Keyword(s):  
Curcuma Longa ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Volatile Composition, Toxicity, Analgesic, and Anti-Inflammatory Activities of Mucuna pruriens

2020 ◽  
Vol 15 (7) ◽  
pp. 1934578X2093232
Author(s):  
Opeyemi N. Avoseh ◽  
Isiaka A. Ogunwande ◽  
Gbenga O. Ojenike ◽  
Fanyana M. Mtunzi
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Opioid Analgesic ◽  
Dry Weight ◽  
Mucuna Pruriens ◽  
Opioid Antagonist ◽  
Flame Ionization ◽  
Proinflammatory Mediators ◽  
Anti Inflammatory ◽  
Anti Inflammation

The volatile constituents, toxicity, antinociception, and anti-inflammatory activities of the essential oil obtained from the leaf of Mucuna pruriens utilis collected from Nigeria are reported. The essential oil was analyzed comprehensively utilizing gas chromatography (GC)-flame ionization detector and GC coupled with mass spectrometry (MS) using the HP-5 column. The antinociceptive and anti-inflammatory assays were analyzed by a hot plate, formalin, and carrageenan-induced edema assays, respectively. The essential oil was obtained in a yield of 0.2% (v/w) calculated on a dry weight basis. A total of 36 compounds representing 94.8% of the oil contents were identified. The oil contained a high content of ( E)-2-hexenal (19.0%), linalool (8.9%), 1-hexanol (6.6%), and trans-dehydroxylinalool oxide (5.2%). The analgesic property of the essential oil was slightly significant ( P < 0.5) only at the third hour for the 400 mg/kg while other doses are less active. The rate of inhibition was moderate (24.1%-54%) during the analgesic phase of the formalin assay. The rate of inhibition at the anti-inflammatory phases of both formalin and carrageenan were significantly high (100%) and P < 0.001 for all the doses during the reaction duration. The potential proinflammatory mechanism might be due to effects on several proinflammatory mediators, including, histamine, serotonin, and bradykinin, and the ability of the essential oils to act as centrally mediated opioid analgesic. Mucuna pruriens essential oils displayed a high anti-inflammation potential and can be used as a potential centrally mediated opioid antagonist against analgesia.

Anti-inflammatory effect of the hydralcoholic extract of Zingiber officinale rhizomes on rat paw and skin edema

Phytomedicine ◽  
2003 ◽  
Vol 10 (5) ◽  
pp. 381-385 ◽  
Author(s):  
S.C. Penna ◽  
M.V. Medeiros ◽  
F.S.C. Aimbire ◽  
H.C.C. Faria-Neto ◽  
J.A.A. Sertié ◽  
...  
Keyword(s):  
Zingiber Officinale ◽  
Anti Inflammatory ◽  
Rat Paw ◽  
Inflammatory Effect

Antiasthma activity of Eucalyptus grandis essential oil and its main constituent: Vasorelaxant effect on aortic smooth muscle isolated from nomotensive rats

2017 ◽  
Vol 2 (2) ◽  
pp. 211-222
Author(s):  
Oluwagbemiga S. Soyingbe ◽  
Tshepiso Jan Makhafola ◽  
Bongiwe P. Mahlobo ◽  
Hussein M. Salahdeen ◽  
Oladipupo A. Lawal ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Essential Oil ◽  
Essential Oils ◽  
Vascular Reactivity ◽  
Airflow Obstruction ◽  
Eucalyptus Grandis ◽  
Traditional Healers ◽  
Inflammatory Disorder ◽  
Aortic Smooth Muscle ◽  
Anti Inflammatory

Asthma is a chronic inflammatory disorder of the airways. It is characterized by an inflammation of the airways causing dysfunction. Asthma is associated with widespread airflow obstruction and increase in airway responsiveness to a variety of stimuli. An asthma attack is accompanied by wheezing, shortness of breath, chest tightness and coughing. The anti-asthmatic and anti-cough activities of the essential oils and 1,8-cineole on rats were assessed. These activities were induced and challenged with histamine and acetylcholine using an ultrasonic nebulizer for asthma and exposure to ammonia for coughs. Anti-inflammatory activities of the essential oils and 1,8-cineole were determined using the cotton pellet granuloma test. Muscle contraction studies where carried out using the vascular reactivity on aortic smooth muscle. The oils exhibited concentration dependent anti-asthma and anti-cough activities. Significantly, 1,8-cineole isolated and purified from the essential oil showed a concentration dependent anti-inflammatory, anti-cough and anti-asthma activity and The essential oils showed vasorelaxant activity. The ability of the essential oils and 1,8-cineole to directly dilate smooth muscle and relieve the stress of bronchial contraction and obstruction of the airways passage validates the use of Eucalyptus grandis as an anti-asthmatic and anti-cough agent. It is concluded that the essential oils have the potential to be used as an anti-asthma and anti-cough therapy. This study also justifies its use by traditional healers in the treatment of asthma and coughs in Zulu folklore medicine.

scholarly journals Anti-inflammatory effects of the essential oils of ginger (Zingiber officinale Roscoe) in experimental rheumatoid arthritis

2016 ◽  
Vol 4 (3) ◽  
pp. 123-131 ◽  
Author(s):  
Janet L. Funk ◽  
Jennifer B. Frye ◽  
Janice N. Oyarzo ◽  
Jianling Chen ◽  
Huaping Zhang ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Essential Oils ◽  
Zingiber Officinale ◽  
Zingiber Officinale Roscoe ◽  
Anti Inflammatory

Anti-inflammatory Effect of Essential Oil fromCitrus aurantiumL. var.amaraEngl

2017 ◽  
Vol 65 (39) ◽  
pp. 8586-8594 ◽  
Author(s):  
Chun-Yan Shen ◽  
Jian-Guo Jiang ◽  
Wei Zhu ◽  
Qin Ou-Yang
Keyword(s):  
Essential Oil ◽  
Anti Inflammatory ◽  
Inflammatory Effect
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