scholarly journals Research Priorities and Resource Allocation in the Investigation of New Drugs for Cancer in Least Developed Countries

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Ricardo Eccard da Silva ◽  
Angélica Amorim Amato ◽  
Débora Dornelas Belchior Costa Andrade ◽  
Alessandra Vanessa Leite e Silva ◽  
Marta Rodrigues de Carvalho ◽  
...  
Keyword(s):  
Resource Allocation ◽  
Clinical Trials ◽  
Research Priorities ◽  
Developed Countries ◽  
New Drugs ◽  
Least Developed Countries ◽  
Middle Income ◽  
Middle Income Countries ◽  
Fund Research ◽  
Low And Middle Income

Cancer incidence has increased significantly in low- and middle-income countries. The priorities of international health research are not always aligned with the global burden of cancer. This study aims to analyze global tendencies in clinical trials in oncology and discuss research priorities and resource allocation in the investigation of new drugs for cancers that significantly affect the least developed countries. This was a retrospective and analytical study that included data collected from the World Health Organization’s International Clinical Trials Registry Platform (ICTRP) in 2014. According to our results, there was a tendency for clinical trials involving breast and lung cancer to be conducted in countries with a lower level of economic development. On the other hand, cervical, stomach, and liver cancer, despite the significant burden that these place on middle- and low-income countries, were studied little among the countries selected. In conclusion, the organizations that most fund research to develop new drugs for cancer treatment continue to show little interest in prioritizing resources to fund research for certain types of cancer such as those of the cervix, stomach, and liver, which have a significant impact in low- and middle-income countries.

scholarly journals Invited commentary on … Mental health research priorities in low- and middle-income countries

2009 ◽  
Vol 195 (4) ◽  
pp. 364-365 ◽  
Author(s):  
Ricardo Araya
Keyword(s):  
Mental Health ◽  
Health Research ◽  
Research Priorities ◽  
Mental Health Research ◽  
Health Priorities ◽  
Middle Income ◽  
Simple Process ◽  
Inequalities In Health ◽  
Middle Income Countries ◽  
Low And Middle Income

SummaryThere are huge inequalities in health research within and between countries. It is argued that this may hinder the process of setting and tackling mental health priorities. If this were true, establishing research priorities would be important. However, this is not a simple process and one must be aware of its limitations. Despite a plethora of declarations, funding for mental health research in low- and middle-income countries remains hard to find. In the absence of funding, establishing research priorities is seen by many as an exercise of lesser importance.

Opportunities and Challenges for Implementing Neurotrauma Prevention Program: A Practical Perspective for Developing Countries

2019 ◽  
Vol 16 (02/03) ◽  
pp. 077-081
Author(s):  
Amrita Ghosh ◽  
Ranabir Pal ◽  
Luis Rafael Moscote-Salazar ◽  
Huber Said Padilla-Zambrano ◽  
Harsh Deora ◽  
...  
Keyword(s):  
Public Health ◽  
Traumatic Brain Injury ◽  
Developed Countries ◽  
Public Health Issue ◽  
Evidence Based ◽  
Middle Income ◽  
Literature Research ◽  
Middle Income Countries ◽  
Literature Searches ◽  
Low And Middle Income

AbstractNeurotrauma is an underestimated and less understood public health issue in low- and middle-income countries for which we need system-based approach to prevention plans. This study was initiated to find rationale of effective plan with projectile vision of neurotrauma prevention. In search of innovative ideas of neurotrauma prevention evidence was explored from the published literature research on traumatic brain injury. Evidence-based global guidelines on recommended content and scheduling on prevention of neurotrauma literature searches data were also synthesized and summarized from research in developed countries. Our study noted that a considerable number of victims of neurotrauma with death and disabilities put mammoth costs to the already compromised health systems of the low- and middle-income countries. We need systems-based four-pronged approach incorporating neurotrauma registry, neurotrauma surveillance, translational research programs, and current approved process for development of clinical guidelines for prevention.

scholarly journals Primary care financing: a systematic assessment of research priorities in low- and middle-income countries

2019 ◽  
Vol 4 (Suppl 8) ◽  
pp. e001483 ◽  
Author(s):  
Felicity Goodyear-Smith ◽  
Andrew Bazemore ◽  
Megan Coffman ◽  
Richard Fortier ◽  
Amanda Howe ◽  
...  
Keyword(s):  
Primary Care ◽  
Research Priorities ◽  
Knowledge Gaps ◽  
Middle Income ◽  
Policy Makers ◽  
Diverse Range ◽  
Middle Income Countries ◽  
Delphi Round ◽  
Research Questions ◽  
Low And Middle Income

IntroductionFinancing of primary healthcare (PHC) is the key to the provision of equitable universal care. We aimed to identify and prioritise the perceived needs of PHC practitioners and researchers for new research in low- and middle-income countries (LMIC) about financing of PHC.MethodsThree-round expert panel consultation using web-based surveys of LMIC PHC practitioners, academics and policy-makers sampled from global networks. Iterative literature review conducted in parallel. First round (Pre-Delphi survey) elicited possible research questions to address knowledge gaps about financing. Responses were independently coded, collapsed and synthesised to two lists of questions. Round 2 (Delphi Round 1) invited panellists to rate importance of each question. In Round 3 (Delphi Round 2), panellists ranked questions in order of importance.ResultsA diverse range of PHC practitioners, academics and policy-makers in LMIC representing all global regions identified 479 knowledge gaps as potentially critical to improving PHC financing. Round 2 provided 31 synthesised questions on financing for rating. The top 16 were ranked in Round 3e to produce four prioritised research questions.ConclusionsThis novel exercise created an expansive and prioritised list of critical knowledge gaps in PHC financing research questions. This offers valuable guidance to global supporters of primary care evaluation and implementation, including research funders and academics seeking research priorities. The source and context specificity of this research, informed by LMIC practitioners and academics on a global and local basis, should increase the likelihood of local relevance and eventual success in implementing the findings.

Stakeholder Views of Clinical Trials in Low- and Middle-Income Countries: A Systematic Review

PEDIATRICS ◽  
2016 ◽  
Vol 137 (2) ◽  
pp. e20152800-e20152800 ◽  
Author(s):  
P. D. Joseph ◽  
P. H. Y. Caldwell ◽  
A. Tong ◽  
C. S. Hanson ◽  
J. C. Craig
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Middle Income ◽  
Stakeholder Views ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals Menstrual hygiene management among adolescent schoolgirls in low- and middle-income countries: research priorities

2016 ◽  
Vol 9 (1) ◽  
pp. 33032 ◽  
Author(s):  
Penelope A. Phillips-Howard ◽  
Bethany Caruso ◽  
Belen Torondel ◽  
Garazi Zulaika ◽  
Murat Sahin ◽  
...  
Keyword(s):  
Research Priorities ◽  
Middle Income ◽  
Menstrual Hygiene ◽  
Middle Income Countries ◽  
Menstrual Hygiene Management ◽  
Hygiene Management ◽  
Low And Middle Income

scholarly journals Global Breast Cancer: The Lessons to Bring Home

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Silvia C. Formenti ◽  
Alan A. Arslan ◽  
Susan M. Love
Keyword(s):  
Breast Cancer ◽  
Developed Countries ◽  
Effective Management ◽  
Middle Income ◽  
Western Countries ◽  
Middle Income Countries ◽  
Common Cancer ◽  
The Us ◽  
Low And Middle Income

Breast cancer is the most common cancer affecting women globally. This paper discusses the current progress in breast cancer in Western countries and focuses on important differences of this disease in low- and middle-income countries (LMCs). It introduces several arguments for applying caution before globalizing some of the US-adopted practices in the screening and management of the disease. Finally, it suggests that studies of breast cancer in LMCs might offer important insights for a more effective management of the problem both in developing as well as developed countries.

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