scholarly journals Chorea Hyperglycemia Basal Ganglia Syndrome in a 63-Year-Old Male

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Michael Sperling ◽  
Roshan Bhowansingh

Chorea hyperglycemia basal ganglia syndrome (CHBG) is a rare condition that manifests within the setting of uncontrolled nonketotic diabetes mellitus. The objective of this case report is to present a patient found to have CHBG and provide a timeline in terms of his workup and subsequent treatment. We also present a commentary on the current understanding of the pathophysiology and treatment and how this was applied to our patient. The case involves a 63-year-old poorly controlled diabetic male who presented with a one-week history of uncontrolled choreiform movements of his left upper extremity. His initial glucose level was 339 mg/dl. HbA1C was 9.9%. CT scan of the head demonstrated an abnormal increased intensity within the right lenticular nucleus and right caudate head most likely due to microcalcifications/mineralization. MRI of the brain demonstrated nonspecific T1 and T2 hyperintense abnormalities in the same area about the right basal ganglia. These findings were consistent with the movement pattern he was displaying and with a diagnosis of CHBG. Gradual control of his blood sugar levels over 48 hours led to resolution of his choreiform symptoms. After better medication adherence as an outpatient, endocrinology follow-up 6 months after discharge found his HbA1C drop to a level of 7.1%. There was no recurrence of his symptoms. CHBG is a rare manifestation of poorly controlled diabetes but is the one that clinicians should be aware of. Early recognition and gradual treatment of elevated blood glucose levels appear to lead to total resolution of choreiform symptoms.

Author(s):  
Jing Dong ◽  
◽  
Yiqun Gao ◽  
Shunji Liang ◽  
Guorong Deng ◽  
...  

Mobile thrombus in the Right Atrium (RA) is a rare condition. Here, we described a case of a 59-year-old male who presented in emergency room with complaints of progressively worsening dyspnea for 7 years. He was normotensive, had elevated jugular venous pressure and clear lungs. ECG revealed ventricular tachycardia. After successfully electrical defibrillation, an urgent 2D echocardiogram was obtained and revealed the enlargement of all heart chambers and a ball-like, mobile mass in the right atrium. An emergent CT scan revealed no sign of pulmonary embolism. Based on morphological features on echocardiogram, we highly suspected it as RA thrombus. The patient was treated with anticoagulant therapy comprising of low molecular heparin and warfarin since he rejected surgical treatment. Repeat echocardiogram was performed 7 days after anticoagulant therapy and showed disappearance of the RA mass. He was subsequently maintained on warfarin (INR=2.4- 3.0) and other medications for heart failure. The patient was followed up as outpatient and kept in good clinical condition. We concluded that early recognition of this rare situation and prompt management can help in preventing life-threatening complications, and anticoagulant therapy was a therapeutic option for RA thrombus.


Neurosurgery ◽  
2009 ◽  
Vol 65 (6) ◽  
pp. E1206-E1207 ◽  
Author(s):  
Yu-Gang Jiang ◽  
Jing Chen ◽  
Yong Peng

Abstract OBJECTIVE Tuberculous brainstem abscess is a clinically rare condition with potentially high mortality and morbidity. We present this report to draw attention to the importance of early recognition and adequate treatment of tuberculous brainstem abscess. CLINICAL PRESENTATION A 24-year-old man complained of longstanding fever, headache, and weakness followed by development of progressive slurred speech and hemiparesis of the right extremities. Magnetic resonance imaging revealed a large thick-walled cystic lesion lying within the brainstem. INTERVENTION The patient demonstrated a remarkable clinical recovery after microsurgery combined with a course of antituberculous therapy. Microbiological and histological findings confirmed the diagnosis of a tuberculous abscess. CONCLUSION Despite its rarity, the tuberculous brainstem abscess must be considered in the differential diagnosis of cystic brainstem mass lesions in vulnerable patients. When confronted with progressing neurological deterioration and poor response to antituberculous therapy, stereotactic or microsurgical management should be considered. Microsurgical excision combined with a complete course of antituberculous therapy in our patient led to a good outcome.


2020 ◽  
Vol 4 (1) ◽  
pp. 77
Author(s):  
Fatma Zulaikha ◽  
Enok Sureskiarti ◽  
Nunung Herlina

Training Make Low Sugar Light Food for Diabetes Mellitus (DM) PatientsAbstract. Diabetes Mellitus (DM) is metabolic disorder, one of the symptoms in this condition is polyphagia (easily hungry). The condition of polyphagia in DM patients can be overcome by providing nutrients that contain low sugar levels so as not to trigger an increase in blood glucose levels in DM patients. Oatmeal crackers biscuit are biscuits made from oats. Quaker oats are nutrients derived from wheat, these nutrients can help treat the condition of type 2 diabetes and can be consumed at all ages. In addition, oats are easy to find. Community service is in the form of training in making biscuit crackers oatmeal chocochips which are processed biscuits with a composition of oats, sweeteners and chocochips. Biscuit is a processed food that is simple, easily made, not found on the market and is the right choice for people with diabetes mellitus. The purpose of this training is to increase cadre knowledge about DM and improve cadre skills in making biscuit crackers oatmeal chocochips. The training was carried out by involving 10 Nasyiatul aisyiyah cadres in Samarinda Ilir, conducted for 8 weeks. The training method was initiated by educating cadres on DM in the first week, followed by training in making biscuits in the second week. 3rd week to 8th week is assistance for cadres in making biscuits while evaluating cadres 'ability in making biscuits and evaluating participants' knowledge about DM. From the evaluation results, the majority of respondents had good knowledge about DM and were able to make biscuits appropriately.Keywords: Training, biscuit, crackers, DMAbstrak. Diabetes Mellitus (DM) merupakan gangguan metabolik, salah satu gejala pada kondisi tersebut yaitu polifagia (mudah lapar). Kondisi polifagia pada penderita DM dapat diatasi dengan pemberian nutrisi yang mengandung kadar gula rendah sehingga tidak memicu kenaikan kadar glukosa darah pada penderita DM. Biscuit crackers oatmeal merupakan biscuit yang berbahan dasar oat. Quaker oats merupakan nutrisi yang berasal dari gandum, nutrisi ini dapat membantu mengobati kondisi diabetes tipe 2 serta dapat dikonsumsi segala usia. Selain itu, oat mudah ditemukan. Pengabdian masyarakat ini berupa pelatihan pembuatan biscuit crackers oatmeal chocochips yang merupakan olahan biscuit dengan komposisi oat, pemanis dan chocochips. Biscuit ini merupakan makanan olahan yang sederhana, mudah dibuat, tidak ditemukan di pasaran dan merupakan pilihan tepat bagi penderita diabetes mellitus. Tujuan pelatihan ini yaitu meningkatkan pengetahuan kader mengenai DM dan meningkatkan ketrampilan kader dalam membuat biscuit crackers oatmeal chocochips.  Pelatihan dilakukan dengan melibatkan 10 kader Nasyiatul aisyiyah Samarinda Ilir, dilakukan selama 8 minggu. Metode pelatihan diawali dengan mengedukasi kader mengenai DM pada minggu pertama, dilanjutkan dengan pelatihan pembuatan biscuit pada minggu kedua. Minggu ke-3 hingga minggu ke-8 merupakan pendampingan bagi kader dalam pembuatan biscuit sekaligus mengevaluasi kemampuan kader dalam pembuatan biscuit serta mengevaluasi pengetahuan peserta mengenai DM. Dari hasil evaluasi didapatkan mayoritas responden memiliki pengetahuan yang baik mengenai DM dan mampu membuat biscuit secara tepat.Kata Kunci: Pelatihan, biskuit, crackers, DM


2013 ◽  
Vol 7 (1) ◽  
pp. 75-77 ◽  
Author(s):  
V De Luna ◽  
V Potenza ◽  
L Garro ◽  
P Farsetti ◽  
R Caterini

Trigger finger is a rare condition in children. In this paper, we report on a 2-year-old boy with multiple congenital bilateral trigger digits. The patient had no history of perinatal trauma, viral or bacterial infections, or metabolic disorders. The patient was treated with physiotherapy for one year. At the one-year follow-up, the boy presented with six trigger fingers (3 on the right hand, 3 on the left hand). Neither thumb was involved. The six trigger fingers were treated surgically: first, the right-hand trigger fingers and, six months later, those of the left hand. After each operation, a 4-week brace in extension was applied to the operated hand. The symptoms were completely resolved after surgical treatment. Many authors have recommended surgical release for the treatment of trigger finger in children; empirical treatment with physiotherapy may be an option when symptoms present or appear at an older age.


2021 ◽  
Vol 9 (06) ◽  
pp. 610-613
Author(s):  
Mohammed Ajamat ◽  
◽  
Naoufal Assoufi ◽  
Youssouf Benmoh ◽  
Amal Satte ◽  
...  

Non-ketotic hyperglycemia with hemichorea-Hemiballismus (HGSC) is a rare complication of a non-equilibrated diabetic disease characterized by a continuous rapid, non-rhythmic, involuntary unilateral movement of the extremities, caused in most cases by decreased activity of the contralateral subthalamic nucleus of the basal ganglia. It may reveal undiagnosed diabetes. We describe here the case of an 84-year-old Moroccan woman followed for type 2 diabetes mellitus under treatment, who presented with abnormal movements of the right half-body. Laboratory tests showed higher blood glucose levels, urinary ketones were negative, brain CT without injection showed high density in the basal ganglia on the left side.


2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Tom P. B. Handley ◽  
Mohammed S. Miah ◽  
Samit Majumdar ◽  
S. S. Musheer Hussain

Purpose. Collet-Sicard syndrome is a very rare condition characterised by unilateral palsy of the IX–XII cranial nerves. It is distinguished from Villaret syndrome by lack of presence of sympathetic involvement. Current literature contains only two cases of Collet-Sicard syndrome due to idiopathic internal jugular vein thrombosis.Method and Results. We report the case of Collet-Sicard syndrome in a 30-year-old man who presented with delayed development of XIth nerve dysfunction, due to internal jugular vein-sigmoid sinus thrombosis. A multidisciplinary team approach was employed in the management of this patient. At three-month followup, he had significantly improved swallowing, and repeat computed tomography neck scan showed partial recanalisation of the right internal jugular vein.Conclusion. In suspected Collet-Sicard syndrome, a focal primary lesion or metastasis to the temporal bone must be excluded, and sigmoid-jugular complex thrombosis should be considered in the differential diagnosis. Early recognition and treatment may result in significant functional recovery.


2007 ◽  
pp. 4-27 ◽  
Author(s):  
V. Polterovich ◽  
V. Popov ◽  
A. Tonis

This paper compares various mechanisms of resource curse leading to a potentially inefficient use of resources; it is demonstrated that each of these mechanisms is associated with market imperfections and can be "corrected" with appropriate government policies. Empirical evidence seems to suggest that resource abundant countries have on average lower budget deficits and inflation, and higher foreign exchange reserves. Besides, lower domestic fuel prices that are typical for resource rich countries have a positive effect on long-term growth even though they are associated with losses resulting from higher energy consumption. On top of that resource abundance allows to reduce income inequalities. So, on the one hand, resource wealth turns out to be conducive to growth, especially in countries with strong institutions. However, on the other hand, resource abundance leads to corruption of institutions and to overvalued real exchange rates. On balance, there is no solid evidence that resource abundant countries grow more slowly than the others, but there is evidence that they grow more slowly than could have grown with the right policies and institutions.


1973 ◽  
Vol 72 (3) ◽  
pp. 475-494 ◽  
Author(s):  
Svein Oseid

ABSTRACT Six cases of congenital generalized lipodystrophy have been studied at different ages from infancy to adolescence with regard to glucose tolerance, insulin secretion, and insulin sensitivity. During the first few years of life there is normal glucose tolerance. The fasting immuno-reactive insulin (IRI) levels are either slightly elevated or normal. The IRI response to glucose is exaggerated and prolonged, at least from the third year of life. Some degree of insulin resistance is already present in infancy. From the age of 8–10 years glucose tolerance decreases rapidly. The fasting IRI levels are usually grossly elevated, while fasting plasma glucose levels are only moderately elevated or normal. The IRI responses to oral and iv administered glucose, and to tolbutamide are exaggerated; the insulinogenic indices are high. Cortisone primed glucose tolerance tests become abnormal. Insulin resistance is marked, and increases with age. After cessation of growth at approximately 12 years of age, frank diabetes with fasting hyperglycaemia and diabetic glucose tolerance curves developed in the one patient followed beyond this age. Her fasting IRI was increased, but there was a poor IRI response to glucose stimulation, suggesting a partial exhaustion of the β-cells. Her initial IRI response to tolbutamide was still good, but not as brisk as in the younger patients. This type of diabetes is quite different from the juvenile form, and also from the diabetes of older age. It may be causally related to the lack of an adequate adipose organ necessary for the disposal of excesses of glucose, or possibly related to another anti-insulin mechanism.


2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Marine Vekua

The main goal of this research is to determine whether the journalism education of the leading media schools inGeorgia is adequate to modern media market’s demands and challenges. The right answer to this main questionwas found after analyzing Georgian media market’s demands, on the one hand, and, on the other hand, differentaspects of journalism education in Georgia: the historical background, development trends, evaluation ofeducational programs and curricula designs, reflection of international standards in teaching methods, studyingand working conditions.


2019 ◽  
Vol 65 (5) ◽  
pp. 756-759
Author(s):  
Mikhail Postolov ◽  
Nadezhda Kovalenko ◽  
K. Babina ◽  
Stanislav Panin ◽  
Yelena Levchenko ◽  
...  

Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal neoplasm characterized by expression of both mela-nocytic and smooth muscle markers. Only 10 primary malignant lung PEComas have been reported up to date. We report a 59-year-old male who presented with a lung neoplasm, found during the routine X-ray examination. Preoperative CT-scan revealed the 3,5-cm-sized mass, located at the border of the upper, middle and lower lobes of the right lung. Patient underwent a thoracotomy, resection of the upper, middle and lower lobes of the right lung accompanied with mediastinal lymphadenectomy. After surgery, chylothorax was revealed. Conservative treatment was unsuccessful, so we performed laparoscopic clipping of the thoracic lymph duct. Patient was dismissed from hospital on the 10-th day after the second operation in good condition. In this report, we intend to increase the limited knowledge relating to natural history and optimal treatment of such a rare condition as a primary malignant lung PEComa.


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