scholarly journals Sternectomy for Treating Advanced Non-Melanoma Skin Cancer

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Victor Emmanuel Gadelha Pinheiro ◽  
Bianca Rohsner Bezerra ◽  
Luís Arthur Brasil Gadelha Farias ◽  
Irapuan Teles de Araujo Filho ◽  
Marcio Ribeiro Studart da Fonseca
Keyword(s):  
Skin Cancer ◽  
Survey Data ◽  
Medical Records ◽  
Clinical Course ◽  
Locally Advanced ◽  
Sunlight Exposure ◽  
Prolonged Survival ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

Introduction. Skin cancer is a rare indication of sternectomy. Our goal is to report the clinical course of seven patients who underwent sternectomy for skin cancer. Methods. The survey data were collected from medical records of patients treated between 2008 and 2018 at Ceará Cancer Institute. Results. All patients had prolonged sunlight exposure and average disease time of two years and age of 60 years. Most patients recovered favorably after treatment with prolonged survival. Conclusion. Sternectomy remains an option with curative purposes for locally advanced skin cancer.

scholarly journals Age distribution of patients with advanced non-melanoma skin cancer in the United States

2013 ◽  
Vol 305 (9) ◽  
pp. 845-850 ◽  
Author(s):  
Stacey Dacosta Byfield ◽  
Diana Chen ◽  
Yeun Mi Yim ◽  
Carolina Reyes
Keyword(s):  
Skin Cancer ◽  
Advanced Disease ◽  
Locally Advanced ◽  
Age Distribution ◽  
Specific Treatment ◽  
The United States ◽  
Non Melanoma Skin Cancer ◽  
Number Of Patients ◽  
Incident Cases ◽  
Melanoma Skin

Abstract The epidemiology of non-melanoma skin cancer (NMSC) is not well understood due to exclusion from most US cancer registries. Patients with at least two claims with a NMSC diagnosis (ICD-9-CM 173.xx) at least 60 days apart, or at least one claim for a NMSC-specific treatment from 1/2010 to 12/2010, were identified from a large US commercial insurance claims database and grouped into one of three cohorts: metastatic (MET), locally advanced (LA), or “all other”. MET patients had at least two claims with a metastasis code at least 30 days apart. LA patients had at least two visits to a medical oncologist, one diagnostic imaging service, two radiation therapy services, or one visit to two or more physician specialties. Remaining patients were “all other”. Incidence and prevalence of NMSC were calculated from among the total number of persons continuously enrolled in the plan during the study period and standardized to the 2010 US population. From among 6,610,256 patients, there were 47,451 incident cases of NMSC (MET n = 16, LA n = 387, all other n = 47,048). The age-adjusted incidence rate of 693 per 100,000 persons (2010 population) approximates to 2,139,535 total NMSC cases in the US (0.7 % of population). 671 prevalent cases had advanced disease (MET n = 43, LA n = 628); an age-adjusted rate of 0.6 and 10 per 100,000 US persons equivalent to 1,993 and 29,841 MET and LA cases, respectively. Although NMSCs rarely progress, the number of patients with advanced disease is significant. Further studies to determine proportions of advanced NMSC by subtype are needed.

Multiple primary skin cancer: case report and literature review

2019 ◽  
Vol 1 (7) ◽  
pp. 78-82 ◽  
Author(s):  
Y. Y. Sergeev ◽  
V. V. Mordovtseva ◽  
O. R. Katunina ◽  
V. Y. Sergeev
Keyword(s):  
Skin Cancer ◽  
Literature Review ◽  
Clinical Course ◽  
Prostate Gland ◽  
Cancer Case ◽  
Secondary Tumor ◽  
Non Melanoma Skin Cancer ◽  
Multiple Primary ◽  
Primary Form ◽  
Melanoma Skin

Multiple primary form of melanoma is one of the variants of the clinical course of this tumor. Typically two primary lesions are diagnosed and secondary tumor differs much in terms of clinical and pathological characteristics. Besides subsequent melanomas, patients are at higher risk of developing non-melanoma skin cancer, tumors of the breast, prostate gland, kidneys and the gastrointestinal tract. The article describes the case of multiple primary skin cancer, manifested by two primary melanomas and basal cell carcinoma, and literature review on this issue.

scholarly journals Vitamin D status and its relation with insulin resistance and VDR-FokI polymorphism in Iranian non-melanoma skin cancer (NMSC) patients: a case-control study

2019 ◽  
Author(s):  
Fatemeh Rezaiian ◽  
Sayed Hossein Davoodi ◽  
Bahareh Nikooyeh ◽  
Amir Houshang Ehsani ◽  
Ali Kalayi ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Skin Cancer ◽  
Case Control Study ◽  
Sunlight Exposure ◽  
Vitamin D Status ◽  
Fasting Serum ◽  
Non Melanoma Skin Cancer ◽  
Control Study ◽  
Melanoma Skin

Abstract Background: Sunlight exposure, the main source of endogenous vitamin D synthesis, may increase the risk of non-melanoma skin cancer (NMSC) development. Vitamin D receptor (VDR) polymorphisms are associated with 25(OH)D levels, cancer development and insulin resistance. This study was aimed to examine the associations among vitamin D status, VDR FokI polymorphism, insulin resistance and NMSC. Methods: This case-control study included 73 diagnosed cases of NMSC and 72 healthy controls from dermatology clinics at Razi Hospital, Tehran, Iran. A questionnaire was used to assess sunlight exposure. The extracted DNA from whole blood samples were genotyped. Fasting serum 25-hydroxyvitaminD (25(OH)D)), lipid profile, glucose, and insulin were measured. To evaluate insulin resistance, HOMA-IR formula was used. Results: We found a significant higher duration of cumulative sunlight exposure in cases compared with controls (p<0.001). However, 25(OH)D concentrations were not significantly different between cases and controls (30±15 vs. 29±15 ng/mL, p=0.78). Higher levels of insulin (p = 0.004) and HOMA-IR score (p= 0.019) were observed in Ff and ff genotype of FokI. We did not observe any significant increased risk of NMSC due to f allele, as compared with FF (OR =2.33, 95% CI 0.81-6.75, p=0.12). The components of lipid profile, fasting serum glucose, iPTH and anthropometric measures did not differ significantly across VDR genotypes. Conclusion: In conclusion, sunlight exposure was associated with NMSC risk. VDR FokI polymorphisms appears to influence insulin resistance in the NMSC patients. Keywords: sun exposure; non-melanoma skin cancer; polymorphisms; insulin resistance

Sign in / Sign up

Export Citation Format

Share Document