scholarly journals Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Woldeteklehaymanot Kassahun ◽  
Girum Tesfaye ◽  
Lealem Gedefaw Bimerew ◽  
Diriba Fufa ◽  
Wondimagen Adissu ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Associated Factors ◽  
Medical Center ◽  
Hematological Parameters ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Lymphoid Leukemia ◽  
Cross Sectional ◽  
Acute Myeloid

Introduction. Leukemia is a heterogeneous group of hematological disorder which comprise several diverse and biologically distinct subgroups. Leukemia represents the 11th and 10th most frequent cause of cancer morbidity and mortality worldwide, respectively. Adequate data regarding the prevalence of leukemia are lacking in Ethiopia, particularly in the study area. This study is aimed to determine the prevalence of leukemia and associated factors among patients who have abnormal hematological parameters in Jimma Medical Center. Methodology. A facility-based cross-sectional study was conducted involving 332 patients who have abnormal hematological parameters. Complete blood count from venous blood was made with Sysmex autohematology analyzer (Sysmex XS-500i and XT-1800; Kobe, Japan). Peripheral blood morphology and bone marrow aspirate examination were done for each patient. Descriptive statistics for the prevalence of leukemia and multinomial logistic regression analysis to assess associated factors were executed with IBM SPSS version 25. Results. The prevalence of leukemia was 9.3%, while acute myeloid leukemia, Acute Lymphoid Leukemia, Chronic Myeloid Leukemia, Chronic Lymphoid Leukemia, Myelodysplastic Syndrome, and undifferentiated leukemia comprises 3.6%, 2.7%, 1.8%, 0.6%, and 0.3%, respectively. Older Age ( p = 0.019 ), being male ( p = 0.047 ), being anemic ( p = 0.03 ), and rural residency of a patient ( p = 0.044 ) were significantly associated with having acute myeloid leukemia. Conclusion. The prevalence of leukemia among patients who have abnormal hematological parameters in Jimma Medical Center is significant which needs further comprehensive investigations of the associated factors and predictors with more up to date diagnostic methods.

scholarly journals Characterization of flow cytometric immuno-phenotyping of acute myeloid leukemia with minimal differentiation and acute T-cell lymphoblastic leukemia: A retrospective cross-sectional study

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 1170
Author(s):  
Enass Abdul Kareem Dagher Al-Saadi ◽  
Marwa Ali Abdulnabi ◽  
Faris Hanoon Jaafar
Keyword(s):  
Flow Cytometry ◽  
Acute Myeloid Leukemia ◽  
T Cell ◽  
Myeloid Leukemia ◽  
Lymphoblastic Leukemia ◽  
Antigen Expression ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Acute Myeloid

Background: Acute leukemias (ALs) are a heterogeneous group of malignancies with various clinical, morphological, immunophenotypic, and molecular characteristics. Distinguishing between lymphoid and myeloid leukemia is often performed by flow cytometry. This study aimed to evaluate the immunophenotypic characterization and expression of immuno-markers in both acute myeloid leukemia (AML-M0) and acute T-cell lymphoblastic leukemia (T-ALL). Methods: A retrospective cross-sectional study was conducted in the Pathology Department/Teaching Laboratories/Medical City/Iraq and included all patients newly diagnosed with AL from 5 January to 10 December 2018. Immunophenotypic analysis was performed on bone marrow samples, freshly collected in EDTA tubes. Flow cytometry (Canto-2 BD) was used, with laser excitation of blue and red wavelengths. A panel of monoclonal antibodies (MoAbs) was used for diagnosis, using a SSC/CD45 gating strategy. Results: The study showed 41.6% of AML-M0 patients had no aberrant antigen expression, while 33.3%, 16.6%,  8.3%, and 8.3% had aberrant CD7, CD56, CD2, and CD19, respectively. In 16.6% of AML-M0 cases more than one aberrant antigen was expressed. With regard to T-ALL, 7.0% were pro-T type, 58.0% were pre-T, 13.0% were cortical, and 22.0% were mature-T type. In 55.5% of patients with T-ALL there was no aberrant antigen expression. Conclusion: We concluded that most patients with AML-M0 have no aberrant antigen expression. In patients with T-ALL, the pre-T type is most common, according to the European Group for the Immunological Classification of Leukemias (EGIL) classification. Patients with T-ALL also generally lack aberrant antigen expression.

Overall survival of Brazilian acute myeloid leukemia patients according to the European LeukemiaNet prognostic scoring system: a cross-sectional study

2018 ◽  
Vol 35 (11) ◽  
Author(s):  
Tarcila Santos Datoguia ◽  
Elvira Deolinda Rodrigues Pereira Velloso ◽  
Ricardo Helman ◽  
Juliane Garcez Musacchio ◽  
Marco Aurélio Salvino ◽  
...  
Keyword(s):  
Overall Survival ◽  
Acute Myeloid Leukemia ◽  
Scoring System ◽  
Myeloid Leukemia ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
System A ◽  
Acute Myeloid

scholarly journals Formulation of Genetic Counseling Format for Adult Bangladeshi Patients with Acute Myeloid Leukemia

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
M. Z. Rahman ◽  
L. Nishat ◽  
Z. A. Yesmin ◽  
L. A. Banu
Keyword(s):  
Acute Myeloid Leukemia ◽  
Genetic Counseling ◽  
Myeloid Leukemia ◽  
English Language ◽  
Mother Tongue ◽  
Group Discussion ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Bangladeshi Population ◽  
Acute Myeloid

With the advancement of medical genetics, particular emphasis is given on the genetic counseling worldwide. In Bangladesh, genetic counseling services are not yet developed. Acute myeloid leukemia (AML) is a malignant disease of the myeloid cells of bone marrow. Like other malignant diseases, it may result from a mutation in the DNA. A genetic counseling format will educate the AML patients and provide appropriate medical and emotional support. The aim of this descriptive cross-sectional study was to develop a genetic counseling format for adult Bangladeshi patients with AML. Taking this into account, a draft format was prepared by reviewing relevant documents available online which was later analyzed by an expert panel through a group discussion and thus a proposed format was developed. To make the format effective in the perspective of Bangladeshi population, the proposed format was applied in counseling, and thus a final format was developed in the English language. This format will educate the counselors, clinicians, and patients about the utility and importance of the genetic counseling and genetic tests. Also, the patients feel comfort regarding the whole counseling process and going for postcounseling treatments and advice. Though it is written in English, it may be translated into mother tongue for better communication during counseling.

scholarly journals Sleep quality and associated factors among pregnant women attending antenatal care at Jimma Medical Center, Jimma, Southwest Ethiopia, 2020: cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tamrat Anbesaw ◽  
Habtamu Abebe ◽  
Chalachew Kassaw ◽  
Tilahun Bete ◽  
Alemayehu Molla
Keyword(s):  
Sleep Quality ◽  
Pregnant Women ◽  
Associated Factors ◽  
Medical Center ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Sectional Study ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
Southwest Ethiopia

Abstract Background Sleep is a natural physiological process vital for the physical and mental wellbeing of pregnant women and their fetuses. Even though poor sleep quality is a common problem among pregnant women, it is not studied in developing countries including Ethiopia. Therefore, this study was aimed to assess the poor sleep quality and associated factors among pregnant women attending antenatal care at Jimma medical center, Jimma, Southwest Ethiopia, 2020. Methods A cross-sectional study design was conducted among 415 pregnant women at Jimma Medical Center (JMC). The study subjects were selected using a systematic random sampling technique. Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality using face-to-face interviews. SPSS version 25 was used to analyze data. Bivariate and multivariable logistic regressions were done to identify factors related to sleep quality. In multivariable logistic regression variables with a p-value less than 0.05 was considered significant and, adjusted OR (AOR) with 95% CI was used to present the strength of the association. Results The prevalence of poor sleep quality among pregnant women was found to be 30.8% (95% CI (26.5, 35.2). In multivariable analysis, age ≥ 30 years old (AOR = 1.94;95%CI:1.03,3.66), Multigravida (AOR = 1.90;95%CI:1.90,3.32),depression (AOR = 4.26;95%CI:2.54,7.14),stress (AOR = 1.85;95%CI:1.20,3.02) were variables significantly associated with poor sleep quality. Conclusion This study found a high prevalence of poor sleep quality among pregnant women. Older age, gravidity, depression, and stress were associated with poor sleep quality. It is better to have routine sleep pattern screening and teach sleep hygiene practice for pregnant women.

Quality of periodic health examination service for employees and associated factors at the New Port Medical Center, Ho Chi Minh city in 2020

2021 ◽  
Vol 05 (04) ◽  
pp. 38-46
Author(s):  
Thi Thuy Pham ◽  
Khac Luong V ◽  
Duc Nguyen ◽  
Quoc Tran Dau ◽  
Nhu Thao Tran
Keyword(s):  
Associated Factors ◽  
Medical Center ◽  
Cross Sectional Study ◽  
Ho Chi Minh City ◽  
Health Examination ◽  
Periodic Health Examination ◽  
Sectional Study ◽  
Cross Sectional ◽  
Overall Health Status

Objectives: A periodic health examination helps people to evaluate the overall health status, so it is of the utmost importance to each individual, including employees. At Saigon Newport Corporation, employees have to do strenuous, hazardous, and dangerous works, so periodic health examination is necessary. Methods: A descriptive cross-sectional study was conducted on 436 employees to measure their perception of the periodic health examination service quality via the SERVPERF scale and associated factors at the New Port Medical Center, Ho Chi Minh City, 2020. Results: Research results indicated that 78% of employees have a good assessment of the quality of periodic health examination, in which reliability was 79.6%, assurance was 79.8%, which were also the least. Conclusions: Gender, level of education, and sector of employment were related to the employees’ perception of the periodic health examination service. Keywords: Periodic health examination, employee, SERVPERF, New Port Medical Center, Saigon Newport Corporation.

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