Uterine Cancer Mortality in White and African American Females in Southeastern North Carolina

The residents of southeastern North Carolina (NC) are exposed to multiple socioeconomic and environmental risk factors and have higher mortality rates for a number of diseases. Uterine cancer mortality is known to vary dramatically by race, so we analyzed uterine cancer mortality in populations defined by zip codes in this area to investigate the contributions of various environmental risk factors to race-specific disease patterns. Methods. Zip code specific mortality and hospital admissions for uterine cancer from 2007 to 2013 were analyzed using the NC State Center for Health Statistics data and the Inpatient Database of the Healthcare Cost and Utilization Project datafiles, respectively. Results were adjusted for age, income, education, health insurance coverage, prevalence of current smokers, and density of primary care providers. Results. Uterine cancer mortality rates were generally higher in African American (32.5/100,000, 95% CI = 18.9–46.1) compared to White (19.6/100,000, 95% CI = 12.3–26.9) females. Odds ratios (ORs) of uterine cancer death were higher in White females (OR = 2.27, p<0.0001) residing within zip codes with hog concentrated animal feeding operations (CAFOs) (hog density >215 hogs/km2) than in White females residing in non-CAFO communities. African American females living near CAFOs had less pronounced increase of uterine cancer death (OR = 1.08, p=0.7657). Conclusion. White females living in adjacent to hog CAFOs areas of southeastern NC have lower rates of mortality from uterine cancer than African American females, but they have higher odds of death compared to their counterparts living in other NC areas. African American females living near CAFOs also have modest increases from their high baseline mortality. While the observed associations do not prove a causation, improving access to screening and medical care is important to mitigate this health issues in southeastern NC.

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Environmental risk factors for Toxoplasma gondii infections and the impact of latent infections on allostatic load in residents of Central North Carolina

BMC Infectious Diseases ◽

10.1186/s12879-018-3343-y ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 8

Author(s):

Andrey I. Egorov ◽

Reagan Converse ◽

Shannon M. Griffin ◽

Jennifer Styles ◽

Elizabeth Klein ◽

...

Keyword(s):

Risk Factors ◽

North Carolina ◽

Toxoplasma Gondii ◽

Environmental Risk ◽

Allostatic Load ◽

Environmental Risk Factors ◽

Latent Infections ◽

The Impact

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Environmental risk factors for breast cancer among African-American women

Cancer ◽

10.1002/cncr.11023 ◽

2002 ◽

Vol 97 (S1) ◽

pp. 289-310 ◽

Cited By ~ 17

Author(s):

Mary S. Wolff ◽

Julie A. Britton ◽

Valerie P. Wilson

Keyword(s):

Breast Cancer ◽

Risk Factors ◽

African American ◽

African American Women ◽

Environmental Risk ◽

Environmental Risk Factors ◽

American Women

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Mortality and Economic Instability: Detailed Analyses for Britain and Comparative Analyses for Selected Industrialized Countries

International Journal of Health Services ◽

10.2190/6xa5-4w36-m8hr-nx1x ◽

1983 ◽

Vol 13 (4) ◽

pp. 563-620 ◽

Cited By ~ 67

Author(s):

M. Harvey Brenner

Keyword(s):

Risk Factors ◽

Infant Mortality ◽

Environmental Risk ◽

Economic Change ◽

The United States ◽

Mortality Rates ◽

Environmental Risk Factors ◽

Change Model ◽

Industrialized Countries ◽

Simple Economic

This paper discusses a first-stage analysis of the link of unemployment rates, as well as other economic, social and environmental health risk factors, to mortality rates in postwar Britain. The results presented represent part of an international study of the impact of economic change on mortality patterns in industrialized countries. The mortality patterns examined include total and infant mortality and (by cause) cardiovascular (total), cerebrovascular and heart disease, cirrhosis of the liver, and suicide, homicide and motor vehicle accidents. Among the most prominent factors that beneficially influence postwar mortality patterns in England/Wales and Scotland are economic growth and stability and health service availability. A principal detrimental factor to health is a high rate of unemployment. Additional factors that have an adverse influence on mortality rates are cigarette consumption and heavy alcohol use and unusually cold winter temperatures (especially in Scotland). The model of mortality that includes both economic changes and behavioral and environmental risk factors was successfully applied to infant mortality rates in the interwar period. In addition, the “simple” economic change model of mortality (using only economic indicators) was applied to other industrialized countries. In Canada, the United States, the United Kingdom, and Sweden, the simple version of the economic change model could be successfully applied only if the analysis was begun before World War II; for analysis beginning in the postwar era, the more sophisticated economic change model, including behavioral and environmental risk factors, was required. In France, West Germany, Italy, and Spain, by contrast, some success was achieved using the simple economic change model.

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