scholarly journals Baseline Levels of Serum Progesterone and the First Trimester Pregnancy Outcome in Women with Threatened Abortion: A Retrospective Cohort Study

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Yongshi Deng ◽  
Chi Chen ◽  
Siyun Chen ◽  
Guanyan Mai ◽  
Xiuping Liao ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pregnancy Outcome ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
First Trimester ◽  
Outcome Variable ◽  
Serum Progesterone ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy ◽  
Threatened Abortion

Objective. The relationship between serum progesterone and the first trimester pregnancy outcome of threatened abortion is still controversial. Therefore, we aimed to further study the association between these two parameters. Methods. The present study is an observational retrospective cohort study. A total of 726 participants who had threatened abortion from a hospital in Guangdong, China, were included in this study from 17th August 2011 to 30th October 2018. The exposure variable and the outcome variable were serum progesterone measured at baseline and early pregnancy outcome, respectively. Covariates involved in this study included patients’ basic demographics, obstetric history, and clinical information. Results. A negative association and a saturation effect were detected between serum progesterone and the first trimester pregnancy outcome. When progesterone <90.62 nmol/L, an increase in 1 nmol/L of serum progesterone was associated with 3% decrease of the risk of miscarriage (OR: 0.97, 95% CI: 0.95-0.98). Conclusion. There was a greater risk of abortion when the serum progesterone level was less than 90.62 nmol/L. Our findings can better assist the clinician in understanding patients’ conditions and making medical decisions.

SARS-CoV-2 in First Trimester Pregnancy: A Cohort Study

2021 ◽  
Vol 76 (4) ◽  
pp. 205-207
Author(s):  
N. la Cour Freiesleben ◽  
P. Egerup ◽  
K. V. R. Hviid ◽  
E. R. Severinsen ◽  
A. M. Kolte ◽  
...  
Keyword(s):  
Cohort Study ◽  
First Trimester ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy

scholarly journals Delivery and pregnancy outcome in women with bowel resection for deep endometriosis: a retrospective cohort study

2015 ◽  
Vol 12 (4) ◽  
pp. 279-285 ◽  
Author(s):  
Silvia Baggio ◽  
Paola Pomini ◽  
Alessandro Zecchin ◽  
Simone Garzon ◽  
Cecilia Bonin ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pregnancy Outcome ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Bowel Resection ◽  
Deep Endometriosis

Prognostic nutritional index and colorectal cancer deaths: A retrospective cohort study in Chinese patients with locally advanced colorectal cancer.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e15160-e15160
Author(s):  
Wenling Wang
Keyword(s):  
Colorectal Cancer ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Inflection Point ◽  
Advanced Colorectal Cancer ◽  
Radical Resection ◽  
Postoperative Treatment ◽  
Outcome Variable ◽  
Local Advanced

e15160 Background: The nutrition and immune status-based scoring system PNI was originally used to assess the nutritional status and surgical risk of surgical patients before surgery. Subsequent studies have shown that PNI is an important prognostic indicator for some malignant tumors, including hepatocellular carcinoma, pancreatic cancer, laryngeal cancer, renal cell carcinoma and gastric cancer. We speculated that since PNI is associated with the prognosis of other malignancies, is it also relevant in colorectal cancer? In view of the obvious increase in the incidence of colorectal cancer in China, and the clinical progress of colorectal cancer in the entire colorectal cancer accounted for up to 70% and current studies on PNI and local advanced colorectal cancer prognosis association study in Chinese is limited. In the present study, our primary objective was to explore whether PNI evaluated at baseline was independently associated with colorectal cancer deaths after controlling other potential confounders. Methods: Through a retrospective cohort study, we analyzed the clinical data of 400 patients with pathologically confirmed colorectal cancer and radical resection of colorectal cancer from January 2013 to April 2018.The exposure variable was PNI at baseline, the outcome variable was death, and other covariates of this study include: Continuous variables: age, platelet count, tumor markers (CEA, CA199, CA724, CA242).Categorical variables: gender, survival status, tumor location, histological type, degree of differentiation, TNM staging, and postoperative treatment. Results: Fully-adjusted model demonstrated that PNI was not associated with deaths of local advanced colorectal cancer and radical resection of colorectal cancer (HR = 0.88; 95% CI, 0.78-1.00). By applying the cubic spline function to the model, we found that the relationship between PNI and death is nonlinear.Two-piecewise cox model suggested that On the left side of the inflection point (41.35), PNI per 1 change is associated with the 68% decrease of risk of deaths (HR = 0.32; 95% CI, 0.13-0.79), to the right of the inflection point, PNI and death The association is not detected. Conclusions: PNI and deaths are nonlinearity, and within a certain range (PNI = 26-41), PNI is an independent protective factor for death risk.

scholarly journals Survival Status and Determinants of Mortality Among Severely Malnourished Children Aged 0-59 Months Admitted to Jinka Hospital, South Omo Zone, Ethiopia: A Retrospective Cohort Study 

2020 ◽  
Author(s):  
Shegaw Abiyu ◽  
Tesfaye Gobena ◽  
Gudina Egata
Keyword(s):  
Cohort Study ◽  
General Hospital ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Outcome Variable ◽  
Major Public Health Problem ◽  
Proportional Hazard ◽  
Global Test ◽  
Survival Status ◽  
Malnourished Children

Abstract Sever acute malnutrition (SAM) remains a major public health problem contributing to morbidity and mortality among children aged 0-59 months. However, little is known about the survival status and determinants of mortality among children admitted to stabilization centers (SC) in Ethiopia particularly in study setting. The objective: to assess the survival status and determinants of mortality among severely malnourished children aged 0-59 months admitted to SC in Jinka general hospital from September 1, 2014 to August 30, 2018. Hospital based retrospective cohort study design was used among 588 severely malnourished children aged 0-59 months admitted to SC of Jinka general hospital from March 20-30, 2019. Simple random sampling method was used to select medical records of the study participants. Proportional hazard assumption over time was checked by Schoenfeld’s global test. The Kaplan-Mei­er survival curve with log-rank test was used to compare survival across groups. Bivariable and multivariable Cox proportional hazard regression was used to assess the association between each independent variable and the outcome variable. Level of statistical significance was declared at p less than 0.05. Among cohort of children studied, nearly 11% of children were died during follow up. The overall mean survival time was 38 days, 95% CI :( 36.3, 39.7).Urban residence [AHR=2.24, 95% CI: (1.17, 4.30)], presence of dehydration [AHR =3.94, 95% CI:(1.89, 8.22)], presence of shock [AHR=4.15, 95% CI:(2.01, 8.55)], altered body temperature [AHR= 2.01, 95% CI:(1.01, 3.91)], failure to take F100 formula milk [AHR= 4.87, 95%CI:(2.75, 8.63)] and oral antibiotics [AHR=3.57, 95%CI:(1.88,6.77)] were identified to be the independent determinants of mortality The mortality rate for severely undernourished children was higher than global sphere standard and national protocol.Societal and individual level determinants of mortality were identified. Therefore, interventions to reduce mortality should focus on altered clinical conditions and comorbidities/ infections.

SIGNIFICANCE OF ULTRASOUND IN CLINICALLY DIAGNOSED CAUSES OF VAGINAL BLEEDING IN FIRST TRIMESTER PREGNANCY

2021 ◽  
pp. 74-75
Author(s):  
Amit Shankhwar ◽  
Prem Siddharth Tripathi ◽  
Saurabh Atram ◽  
Pankaj Kujur ◽  
Prakhar Nigam ◽  
...  
Keyword(s):  
Clinical Diagnosis ◽  
Vaginal Bleeding ◽  
Imaging Modality ◽  
First Trimester ◽  
First Trimester Pregnancy ◽  
Incomplete Abortion ◽  
Trimester Pregnancy ◽  
Highly Sensitive ◽  
History Of ◽  
Threatened Abortion

Background: (1) Nearly one-fourth (20-25%) of all pregnant women present with history of vaginal bleeding during the rst trimester . Ultrasound imaging plays an important role in determining the causes of vaginal bleeding during rst trimester of pregnancy. Aims & Objectives:To evaluate the signicance of ultrasound in clinically diagnosed causes of vaginal bleeding in rst trimester pregnancy. Methods: 100 women with vaginal bleeding during rst trimester of pregnancy with clinical diagnosis were evaluated by ultrasonography [USG] and interpretation was compared. Results: Among these 100 cases, threatened abortion was the commonest cause of bleeding (30%) followed by incomplete abortion. Disparity was found between clinical diagnosis of rst trimester vaginal bleed and ultrasound diagnosis. Ultrasound is highly sensitive and specic in diagnosing all causes of rst trimester vaginal bleed including ectopic pregnancy. Conclusion: With good diagnostic performance, USG proves to be an important imaging modality in determining the causes of vaginal bleeding during rst trimester of pregnancy and thus provides an aid for clinicians in better management of patients.

Sign in / Sign up

Export Citation Format

Share Document