scholarly journals Assessment of Visual and Brainstem Auditory Evoked Potentials in Patients with Hashimoto’s Thyroiditis

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Marta Waliszewska-Prosół ◽  
Maria Ejma
Keyword(s):  
Nervous System ◽  
Evoked Potentials ◽  
Neurological Examination ◽  
Hashimoto’S Thyroiditis ◽  
Auditory Evoked Potentials ◽  
Hashimoto's Thyroiditis ◽  
Bioelectrical Activity ◽  
Brainstem Auditory Evoked Potentials ◽  
System Involvement ◽  
The Mean

Background. The present study was aimed to evaluate parameters of visual and brainstem auditory evoked potentials (VEP, BAEP) in euthyreotic Hashimoto’s thyroiditis (HT) patients without central nervous system involvement. Methods. 100 HT patients (92 women, 8 men), mean age 46.9 years, and 50 healthy controls. They underwent a neurological examination, thyroid hormone levels, thyroid autoantibody titers, and brain imaging. Latencies and amplitudes of the N75, P100, and N145 component of VEP and the I-V components of BAEP were analyzed. Results. The neurological examination revealed in 31 patients signs of increased neurovegetative excitability. Brain resonance imaging showed no abnormalities in HT patients. The mean P100, relative P100, and N145 VEP latencies were significantly longer, and P100 amplitude significantly higher in HT patients than the controls. HT patients also had a longer mean wave BAEP V latency and mean wave III-V and I-V interpeak latencies, and significantly lower mean wave I and V amplitudes. Abnormal VEP and BAEP were recorded in 34% of the patients. There were no statistically significant correlations between the mean VEP parameters and thyroid profile and the applied dose of L-thyroxine. There was a relationship between the level of TSH and the wave BAEP III-V interpeak latency. Conclusions. There were changes in the brain’s bioelectrical activity in one-third of the patients with HT without nervous system involvement. The increased amplitude of the VEP may indicate increased cerebral cortex activity. Disorders of the brain’s bioelectrical activity in the course of HT may be associated with an autoimmune process.

scholarly journals The Relationship between Occupationally Exposed Arsenic, Cadmium and Lead and Brain Bioelectrical Activity—A Visual and Brainstem Auditory Evoked Potentials Study

2021 ◽  
Vol 11 (3) ◽  
pp. 350
Author(s):  
Marta Waliszewska-Prosół ◽  
Maria Ejma ◽  
Paweł Gać ◽  
Anna Szymańska-Chabowska ◽  
Magdalena Koszewicz ◽  
...  
Keyword(s):  
Occupational Exposure ◽  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Evoked Potential ◽  
Zinc Protoporphyrin ◽  
Brainstem Auditory Evoked Potentials ◽  
Occupationally Exposed ◽  
The Mean ◽  
Cadmium And Lead ◽  
The Relationship

The aim of this study was to evaluate the parameters of visual and brainstem auditory evoked potentials in patients occupationally exposed to arsenic, cadmium and lead. The study group comprised 41 copper smelter and refinery workers (average age: 51.27) with occupational exposure to arsenic, cadmium and lead. The control group consisted of 36 healthy volunteers (35 men and 1 woman, aged 27–66, average age: 51.08). Neurological examination, brain imaging, and visual and brainstem auditory evoked potentials were performed, and the relationship between blood Cd, Pb concentration (Cd-B, Pb-B), blood zinc protoporphyrin (ZnPP), and urine As concentration (As-U) were assessed. In the workers, exceedances of allowable biological concentrations were observed, with the urinary concentration of arsenic being 5.2%, the cadmium and lead in blood being 1.3%, while the case of ZnPP was 2.6%. The mean P100, relative P100, and N145 visual evoked potential (VEP) latencies were significantly longer in exposed workers than in the controls. The mean wave III and V brainstem auditory evoked potential (BAEP) latency and the mean wave III–V and I–V interpeak latencies were longer, and the I and V amplitude was lower in the workers than the controls. In summary, occupational exposure to As, Cd, and Pb is associated with prolonged latency and reduced evoked potential amplitude, but As-U, Pb-B, Cd-B, and ZnPP concentrations are not linearly related to potential components. The analysis of evoked potentials may be a useful method of assessment of the central nervous system in patients with occupational exposure to heavy metals.

scholarly journals Brainstem Auditory Evoked Potentials in Raccoon Dogs (Nyctereutes procynoides)

Animals ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 233
Author(s):  
Raluca Ștefănescu ◽  
Constantin Roman ◽  
Liviu Dan Miron ◽  
Gheorghe Solcan ◽  
Vasile Vulpe ◽  
...  
Keyword(s):  
Nervous System ◽  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Cost Effective ◽  
Viral Diseases ◽  
System Function ◽  
Brainstem Auditory Evoked Potentials ◽  
Eastern Asia ◽  
Noninvasive Technique ◽  
Raccoon Dogs

Raccoon dogs (Nyctereutes procynoides) are canids indigenous to Eastern Asia being one of the most invasive non-native animals in Europe and potential vectors for several hazardous parasitic and viral diseases. To present, there is a lack of studies regarding objective techniques used to appreciate the integrity and functionality of the nervous system in this species. Brainstem auditory evoked potentials (BAER) is a cost-effective, quick and noninvasive technique to assess the functionality of nervous system. The aim of the study is to provide reference values and evaluates the reliability of BAER recording with needle electrodes in clinically healthy raccoon dogs. Nine individuals were investigated for BAER under xylazine and ketamine general anesthesia. Four waves (I, II, III and V) were identified and evaluated for latencies, morphologically similarity to those previously reported for other species (dogs, horses, cats, and ferret). Our data can be used in further studies to asses objectively the auditory system function in raccoon dogs.

Vitamin D Treatment in Patients with Hashimoto’s Thyroiditis may Decrease the Development of Hypothyroidism

2016 ◽  
Vol 86 (1-2) ◽  
pp. 9-17 ◽  
Author(s):  
Bekir Ucan ◽  
Mustafa Sahin ◽  
Muyesser Sayki Arslan ◽  
Nujen Colak Bozkurt ◽  
Muhammed Kizilgul ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Hashimoto’S Thyroiditis ◽  
Healthy Control Group ◽  
Hashimoto's Thyroiditis ◽  
Control Group ◽  
Endocrine Society ◽  
Thyroid Autoantibody ◽  
Healthy Control ◽  
The Mean

Abstract.The relationship between Hashimoto’s thyroiditis and vitamin D has been demonstrated in several studies. The aim of the present study was to evaluate vitamin D concentrations in patients with Hashimoto’s thyroiditis, the effect of vitamin D therapy on the course of disease, and to determine changes in thyroid autoantibody status and cardiovascular risk after vitamin D therapy. We included 75 patients with Hashimoto’s thyroiditis and 43 healthy individuals. Vitamin D deficiency is defined as a 25-hydroxy vitamin D (25(OH)D3) concentration less than 20ng/mL. Vitamin D deficient patients were given 50.000 units of 25(OH)D3 weekly for eight weeks in accordance with the Endocrine Society guidelines. All evaluations were repeated after 2 months of treatment. Patients with Hashimoto’s thyroiditis had significantly lower vitamin D concentrations compared with the controls (9.37±0.69 ng/mL vs 11.95±1.01 ng/mL, p < 0.05, respectively). Thyroid autoantibodies were significantly decreased by vitamin D replacement treatment in patients with euthyroid Hashimoto’s thyroiditis. Also, HDL cholesterol concentrations improved in the euthyroid Hashimoto group after treatment. The mean free thyroxine (fT4) concentrations were 0.89±0.02 ng/dL in patients with Hashimoto’s thyroiditis and 1.07±0.03 ng/dL in the healthy control group (p < 0.001). The mean thyroid volumes were 7.71±0.44 mL in patients with Hashimoto’s thyroiditis and 5.46±0.63 mL in the healthy control group (p < 0.01). Vitamin D deficiency is frequent in Hashimoto’s thyroiditis and treatment of patients with this condition with Vitamin D may slow down the course of development of hypothyroidism and also decrease cardiovascular risks in these patients. Vitamin D measurement and replacement may be critical in these patients.

The influence of ototoxic drugs on brainstem auditory evoked potentials in man

1981 ◽  
Vol 233 (2) ◽  
pp. 189-199 ◽  
Author(s):  
J. -M. Guerit ◽  
P. Mahieu ◽  
S. Houben-Giurgea ◽  
S. Herbay
Keyword(s):  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Brainstem Auditory Evoked Potentials ◽  
Ototoxic Drugs
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