COVID-19 and APOL-1 High-Risk Genotype-Associated Collapsing Glomerulonephritis

Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the lungs and can lead to acute respiratory distress syndrome (ARDS). The ongoing global pandemic has created healthcare and economic crisis for almost every nation of the world. Though primarily affecting the lungs, it has also affected the kidney in various ways including acute kidney injury (AKI), proteinuria, and hematuria. It has been increasingly shown that African American (AA) individuals affected with COVID-19 and presenting with AKI and nephrotic-range proteinuria are very susceptible to focal segmental glomerulosclerosis (FSGS). The APOL-1 gene, associated with the African American population, has been increasingly recognized as a risk factor for FSGS affected with COVID-19. Our case highlights a similar case of COVID-19 in a 65-year-old AA descendant with biopsy-proven FSGS and genetically confirmed APOL-1 alleles.

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COVID-19- or Tramadol-induced Seizure: A Differential Diagnosis in Young People

International Journal of Medical Toxicology and Forensic Medicine ◽

10.32598/ijmtfm.v10i4.32009 ◽

2020 ◽

Vol 10 (4) ◽

pp. 32009.1-32009.2

Author(s):

Solmaz Nekoueifard ◽

◽

Mohammad Majidi ◽

Keyword(s):

Myocardial Infarction ◽

Acute Kidney Injury ◽

Differential Diagnosis ◽

Acute Respiratory Distress Syndrome ◽

Distress Syndrome ◽

Kidney Injury ◽

World Health ◽

The World ◽

Life Threatening ◽

Health Organization

Coronavirus disease 2019 (COVID-19) was first declared in December 2019 from Wuhan, China [1, 2]. It then has been reported a pandemic in March 2020 by the World Health Organization [3]. Clinical features of COVID-19 are different from asymptomatic to mild to moderate symptoms, such as fever, headache, myalgia, sore throat, anosmia, cough, fatigue headache, hemoptysis, and dyspnea to the life-threatening complications, including shock, pneumonia, acute respiratory distress syndrome, myocarditis, myocardial infarction, acute kidney injury, multi-organ failure, and even death [1, 2].

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ASSESSMENT OF SERUM CYSTATIN C AS AN EARLY PREDICTOR OF ACUTE KIDNEY INJURY IN PRETERM NEONATES WITH RESPIRATORY DISTRESS SYNDROME

10.26226/morressier.57d034d2d462b80292383764 ◽

2016 ◽

Author(s):

Abdelmoneim khashana

Keyword(s):

Acute Kidney Injury ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Cystatin C ◽

Distress Syndrome ◽

Kidney Injury ◽

Preterm Neonates ◽

Serum Cystatin C ◽

Serum Cystatin ◽

Early Predictor

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Association between positive end-expiratory pressure and central venous pressure towards acute kidney injury in COVID-19 acute respiratory distress syndrome: A case series

10.26226/morressier.5fa2cf404d4e91fe5c54b840 ◽

2020 ◽

Author(s):

Marilaeta Cindryani

Keyword(s):

Acute Kidney Injury ◽

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Venous Pressure ◽

Case Series ◽

Kidney Injury ◽

Positive End Expiratory Pressure ◽

Central Venous

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Faculty Opinions recommendation of Systematic review of hearing loss genes in the African American population.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.735638749.793561472 ◽

2019 ◽

Author(s):

Brian Reilly ◽

Chloe Harrington

Keyword(s):

Systematic Review ◽

Hearing Loss ◽

African American ◽

American Population ◽

African American Population

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Screening for ATM Mutations in an African-American Population to Identify a Predictor of Breast Cancer Susceptibility

10.21236/ada421128 ◽

2003 ◽

Author(s):

Barry S. Rosenstein

Keyword(s):

Breast Cancer ◽

African American ◽

Cancer Susceptibility ◽

Breast Cancer Susceptibility ◽

American Population ◽

African American Population

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African-American Population Is More Vulnerable to Sars-CoV2 Infection and IFN-Beta Supplement Can Be An Effective Treatment

SSRN Electronic Journal ◽

10.2139/ssrn.3566710 ◽

2020 ◽

Cited By ~ 2

Author(s):

Amit Maiti

Keyword(s):

African American ◽

Effective Treatment ◽

American Population ◽

African American Population

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Emancipation and Free African Americans

10.1093/oso/9780190676643.003.0003 ◽

2017 ◽

Author(s):

Richard Archer

Keyword(s):

African American ◽

African Americans ◽

New England ◽

Rhode Island ◽

New Hampshire ◽

Jim Crow ◽

African Descent ◽

American Population ◽

African American Population ◽

Free African Americans

Except in parts of Rhode Island and Connecticut, slavery was a peripheral institution, and throughout New England during and after the Revolution there was widespread support to emancipate slaves. Some of the states enacted emancipation laws that theoretically allowed slavery to continue almost indefinitely, and slavery remained on the books as late as 1857 in New Hampshire. Although the laws gradually abolished slavery and although the pace was painfully slow for those still enslaved, the predominant dynamic for New England society was the sudden emergence of a substantial, free African American population. What developed was an even more virulent racism and a Jim Crow environment. The last part of the chapter is an analysis of where African Americans lived as of 1830 and the connection between racism and concentrations of people of African descent.

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