scholarly journals A Clinical Retrospective Study of Recurrent Painful Ophthalmoplegic Neuropathy in Adults

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Cheng Li ◽  
Xinyi Huang ◽  
Xiao Tan ◽  
Yannan Fang ◽  
Jianhua Yan
Keyword(s):  
Retrospective Study ◽  
Diagnostic Criteria ◽  
Clinical Features ◽  
Retrospective Review ◽  
Cranial Nerve ◽  
Diagnosis And Treatment ◽  
Glucocorticoid Treatment ◽  
Eye Symptoms ◽  
Recurrent Painful Ophthalmoplegic Neuropathy ◽  
Symptoms And Signs

Introduction. Recurrent painful ophthalmoplegic neuropathy (RPON) is quite rare and usually occurs in children. In this report, we describe the clinical features, diagnosis, and treatment of RPON in adults. Methods. A retrospective review was conducted of all RPON cases seen and treated at the Zhongshan Ophthalmic Center of Sun Yat-sen University and the Department of Neurology of the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, over the period from January 2016 to May 2020. Results. A total of 8 patients (3 males and 5 females) with a mean age of 42.9 years (range: 23–64 years) met the diagnostic criteria of RPON. Headaches were present prior to the onset of ophthalmoplegic neuropathy in 50% of these patients, while in the remaining 50%, headaches occurred simultaneously with eye symptoms. The degree of these headaches was described as being mild or moderate. Abnormalities involving cranial nerve III were the most frequently reported pathologies (6 cases, 75%), followed by nerve VI (4 cases, 50%) and then nerve IV (1 case, 12.5%) (more than one nerve was affected in some cases). Following either with glucocorticoid treatment or with observation only, symptoms and signs within all 8 patients completely dissipated within 3–28 days. Conclusions. All adult cases of RPON along with their clinical features as reported here were similar to those of children.

scholarly journals Historical and Clinical Features of Psychogenic Tremor: a Review of 70 Cases

1999 ◽  
Vol 26 (3) ◽  
pp. 190-195 ◽  
Author(s):  
Yun J. Kim ◽  
Anthony S.-I. Pakiam ◽  
Anthony E. Lang
Keyword(s):  
Diagnostic Criteria ◽  
Clinical Features ◽  
Retrospective Review ◽  
Clinical Characteristics ◽  
Senior Author ◽  
Spontaneous Resolution ◽  
Accurate Diagnosis ◽  
Functional Symptoms ◽  
Characteristic Features ◽  
Symptoms And Signs

Objectives:To review the clinical characteristics and associated features found in patients with psychogenic tremor.Methods:Ten-year retrospective review of charts of all patients and videotapes of fifty-one patients diagnosed by the senior author as having psychogenic tremor.Results:Seventy patients fulfilled the diagnostic criteria for clinically definite psychogenic tremors. Psychogenic tremors usually started abruptly (73%), often with the maximal disability at onset (46%), and then took static (46%) or fluctuating (17%) courses. Psychogenic tremors usually started in one limb and spread rapidly to a generalized or mixed distribution. Spontaneous resolution and recurrence, easy distractibility together with entrainment and response to suggestion were characteristic features. Presence of functional symptoms and signs and refractoriness to conventional antitremor drugs were common.Conclusion:Psychogenic tremor is generally not a diagnosis of exclusion. The presence of characteristic features on history and especially clinical examination can permit an accurate diagnosis and avoid unnecessary investigations.

Proposed modified diagnostic criteria for recurrent painful ophthalmoplegic neuropathy: Five case reports and literature review

Cephalalgia ◽  
2020 ◽  
Vol 40 (14) ◽  
pp. 1657-1670
Author(s):  
Yinglu Liu ◽  
Miao Wang ◽  
Xiangbing Bian ◽  
Enchao Qiu ◽  
Xun Han ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
Cranial Nerve ◽  
Current Knowledge ◽  
Case Reports ◽  
Case Series ◽  
Oculomotor Nerve ◽  
Multiplanar Reformation ◽  
Unilateral Headache ◽  
Pubmed Database ◽  
Recurrent Painful Ophthalmoplegic Neuropathy

Background Recurrent painful ophthalmoplegic neuropathy (RPON) is an uncommon disorder characterized by recurrent unilateral headache attacks associated with ipsilateral ophthalmoplegia. We intend to study the clinical picture in our case series along with the published literature to discuss the pathogenesis and propose modified diagnostic criteria for recurrent painful ophthalmoplegic neuropathy. Methods We reported five cases diagnosed as ophthalmoplegic migraine/RPON in our medical centers and reviewed the published literature related to RPON from the Pubmed database between 2000 and 2020. In one of these cases, a multiplanar reformation was performed to look at the aberrant cranial nerve. Results The mean onset age for RPON was 22.1 years, and the oculomotor nerve was the most commonly involved cranial nerve (53.9%) in 165 reviewed patients. In most patients, ophthalmoplegia started within 1 week of the headache attack (95.7%, 67/70). Additionally, 27.6% (40/145) of patients presented enhancement of the involved nerve(s) from MRI tests. Finally, 78 patients received corticosteroids, out of which 96.2% benefited from them. Conclusion This is the first time multiplanar reformation has been performed to reveal the distortion of the oculomotor nerve. Modified diagnostic criteria are proposed. We hope to expand the current knowledge and increase the detection of recurrent painful ophthalmoplegic neuropathy in the future.

scholarly journals Updates in Diagnosis and Treatment of Acromegaly

2018 ◽  
Vol 14 (2) ◽  
pp. 57 ◽  
Author(s):  
Roula Zahr ◽  
Maria Fleseriu
Keyword(s):  
Growth Hormone ◽  
Pituitary Adenoma ◽  
Early Diagnosis ◽  
Rare Disease ◽  
Diagnostic Criteria ◽  
Clinical Features ◽  
Morbidity And Mortality ◽  
Diagnosis And Treatment ◽  
Personalised Therapy ◽  
Gh Excess

Acromegaly is a rare disease, caused largely by a growth hormone (GH) pituitary adenoma. Incidence is higher than previously thought. Due to increased morbidity and mortality, if not appropriately treated, early diagnosis efforts are essential. Screening is recommended for all patients with clinical features of GH excess. There is increased knowledge that classical diagnostic criteria no longer apply to all, and some patients can have GH excess with normal GH response to glucose. Treatment is multifactorial and personalised therapy is advised.

The clinical features of mania and their representation in modern diagnostic criteria

2016 ◽  
Vol 47 (6) ◽  
pp. 1013-1029 ◽  
Author(s):  
K. S. Kendler
Keyword(s):  
Diagnostic Criteria ◽  
20Th Century ◽  
Clinical Features ◽  
Strong Relationship ◽  
Diagnostic Systems ◽  
Clinical Evaluations ◽  
Dsm 5 ◽  
Moral Standards ◽  
Mood Lability ◽  
Symptoms And Signs

This review seeks to determine the degree to which modern operationalized diagnostic criteria for mania reflect the clinical features of mania described historically by expert textbook authors. Clinical descriptions of mania appearing in 18 textbooks published between 1899 and 1956 were reviewed and compared to the criteria for mania from six modern operationalized diagnostic systems. Twenty-two prominent symptoms and signs were reported by five or more authors. Two symptoms (elevated mood and grandiosity) and four signs (hyperactivity, pressured speech, irritability, and new activities with painful consequences) were reported by every author. A strong relationship was seen between the frequency with which the clinical features were reported and the likelihood of their inclusion in modern diagnostic systems. However, many symptoms and signs including impulsivity, hypersexuality, mood lability, altered moral standards, increased humor, hypergraphia, and a vigorous physical appearance were not included in any modern criteria. Indeed, DSM-5 contains only eight of the historically noted clinical features. We conclude that modern operationalized criteria for mania well reflect symptoms and signs frequently reported by historical experts. This suggests that the clinical construct of mania has been relatively stable in western Psychiatry since the turn of the 20th century. However, many useful clinical features of mania described in these textbooks are missing from these criteria thereby illustrating the limitations of clinical evaluations restricted to the assessment of only current diagnostic criteria. The disorders we study and treat are considerably richer clinically than is reflected in the DSM criteria which we use to diagnose them.

scholarly journals Clinical features, diagnosis and treatment of respiratory M. pneumoniae infection in children

2019 ◽  
pp. 91-98
Author(s):  
A. L. Zaplatnikov ◽  
A. A. Girina ◽  
I. D. Maykova ◽  
N. V. Karoid ◽  
I. V. Lepiseva ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Respiratory Tract ◽  
Rational Choice ◽  
Diagnostic Criteria ◽  
Clinical Features ◽  
Mycoplasma Pneumoniae ◽  
Respiratory Infections ◽  
State Of The Art ◽  
Community Acquired Pneumonia ◽  
Diagnosis And Treatment

The article describes state-of-the-art knowledge regarding etiology, epidemiology, clinical features and diagnostic criteria for respiratory infections caused by Mycoplasma pneumoniae (M. pneumoniae). It presents the characteristics of the main forms of lesions in mycoplasma infections of the respiratory tract – pharyngitis, bronchitis and pneumonia. Particular attention is paid to the differential diagnosis of community-acquired pneumonia of pneumococcal and mycoplasma etiology. The issues of rational choice of initial etiotropic therapy for the treatment of respiratory mycoplasmosis in children are discussed.

Facet syndrome: causes, clinical features, diagnosis and treatment

2016 ◽  
Vol 18 (2) ◽  
pp. 53-61 ◽  
Author(s):  
A.I. Isaykin ◽  
◽  
I.V. Kuznetsov ◽  
A.V. Kavelina ◽  
M.A. Ivanova ◽  
...  
Keyword(s):  
Clinical Features ◽  
Diagnosis And Treatment ◽  
Facet Syndrome

237 Retrospective Review of Symptoms and Signs of Intussusception Present on Initial Evaluation

2015 ◽  
Vol 66 (4) ◽  
pp. S86
Author(s):  
R.W. Wolford ◽  
B. Browning
Keyword(s):  
Retrospective Review ◽  
Initial Evaluation ◽  
Symptoms And Signs
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