Inhibition of phosphatidylinositol 3-kinase sensitizes ovarian cancer cells to carboplatin and allows adjunct chemotherapy treatment

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-05-0192 ◽

2005 ◽

Vol 4 (11) ◽

pp. 1764-1771 ◽

Author(s):

Suzanne D. Westfall ◽

Michael K. Skinner

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Ovarian Cancer Cells ◽

Chemotherapy Treatment ◽

Phosphatidylinositol 3 Kinase ◽

Phosphatidylinositol 3

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Abstract 1722: c-Met overexpression contributes to the acquired apoptotic resistance of non-adherent ovarian cancer cells through a cross-talk mediated by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2

10.1158/1538-7445.am10-1722 ◽

2010 ◽

Author(s):

Maggie K. S. Tang ◽

Hong Y. Zhou ◽

Judy W. P. Yam ◽

Alice S. T. Wong

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Ovarian Cancer Cells ◽

Phosphatidylinositol 3 Kinase ◽

Extracellular Signal Regulated Kinase ◽

Extracellular Signal ◽

Phosphatidylinositol 3

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A gene signature-based approach identifies thioridazine as an inhibitor of phosphatidylinositol-3′-kinase (PI3K)/AKT pathway in ovarian cancer cells

Gynecologic Oncology ◽

10.1016/j.ygyno.2010.10.003 ◽

2011 ◽

Vol 120 (1) ◽

pp. 121-127 ◽

Author(s):

Seung Bae Rho ◽

Boh-Ram Kim ◽

Sokbom Kang

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Gene Signature ◽

Akt Pathway ◽

Ovarian Cancer Cells ◽

Phosphatidylinositol 3 Kinase ◽

Phosphatidylinositol 3

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Girinimbine Inhibits the Proliferation of Human Ovarian Cancer Cells In Vitro via the Phosphatidylinositol-3-Kinase (PI3K)/Akt and the Mammalian Target of Rapamycin (mTOR) and Wnt/β-Catenin Signaling Pathways

Medical Science Monitor ◽

10.12659/msm.910137 ◽

2018 ◽

Vol 24 ◽

pp. 5480-5487 ◽

Author(s):

Qiu Xin ◽

An Muer

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Signaling Pathways ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Ovarian Cancer Cells ◽

Human Ovarian Cancer ◽

Phosphatidylinositol 3 Kinase ◽

Phosphatidylinositol 3

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c-Met Overexpression Contributes to the Acquired Apoptotic Resistance of Nonadherent Ovarian Cancer Cells through a Cross Talk Mediated by Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase 1/2

Neoplasia ◽

10.1593/neo.91438 ◽

2010 ◽

Vol 12 (2) ◽

pp. 128-IN5 ◽

Author(s):

Maggie K.S. Tang ◽

Hong Y. Zhou ◽

Judy W.P. Yam ◽

Alice S.T. Wong

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Ovarian Cancer Cells ◽

Phosphatidylinositol 3 Kinase ◽

Extracellular Signal Regulated Kinase ◽

Extracellular Signal ◽

Phosphatidylinositol 3

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Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells

Gynecologic Oncology ◽

10.1016/j.ygyno.2006.08.048 ◽

2007 ◽

Vol 104 (2) ◽

pp. 470-479 ◽

Author(s):

Brandi R. Whitley ◽

Lea M. Beaulieu ◽

Jennifer C. Carter ◽

Frank C. Church

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Plasminogen Activator ◽

Plasminogen Activator Inhibitor ◽

Ovarian Cancer Cells ◽

Phosphatidylinositol 3 Kinase ◽

Plasminogen Activator Inhibitor 1 ◽

Activator Inhibitor ◽

Phosphatidylinositol 3

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Gonadotropins Activate Proteolysis and Increase Invasion through Protein Kinase A and Phosphatidylinositol 3-Kinase Pathways in Human Epithelial Ovarian Cancer Cells

Cancer Research ◽

10.1158/0008-5472.can-05-1785 ◽

2006 ◽

Vol 66 (7) ◽

pp. 3912-3920 ◽

Author(s):

Jung-Hye Choi ◽

Kyung-Chul Choi ◽

Nelly Auersperg ◽

Peter C.K. Leung

Keyword(s):

Ovarian Cancer ◽

Protein Kinase ◽

Epithelial Ovarian Cancer ◽

Protein Kinase A ◽

Cancer Cells ◽

Ovarian Cancer Cells ◽

Phosphatidylinositol 3 Kinase ◽

Kinase A ◽

Phosphatidylinositol 3

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RNA Interference-Mediated Silencing of the Phosphatidylinositol 3-Kinase Catalytic Subunit Attenuates Growth of Human Ovarian Cancer Cells in vitroand in vivo

Oncology ◽

10.1159/000218201 ◽

2009 ◽

Vol 77 (1) ◽

pp. 22-32 ◽

Author(s):

Xi Zhang ◽

Hong-xin Deng ◽

Xia Zhao ◽

Dan Su ◽

Xian-chen Chen ◽

...

Keyword(s):

Ovarian Cancer ◽

Rna Interference ◽

Cancer Cells ◽

Catalytic Subunit ◽

Ovarian Cancer Cells ◽

Human Ovarian Cancer ◽

Phosphatidylinositol 3 Kinase ◽

Phosphatidylinositol 3

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Wogonin Increases Cisplatin Sensitivity in Ovarian Cancer Cells Through Inhibition of the Phosphatidylinositol 3-Kinase (PI3K)/Akt Pathway

Medical Science Monitor ◽

10.12659/msm.913829 ◽

2019 ◽

Vol 25 ◽

pp. 6007-6014 ◽

Author(s):

Feng Xing ◽

Cong Sun ◽

Ning Luo ◽

Yuanying He ◽

Mengmeng Chen ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Akt Pathway ◽

Ovarian Cancer Cells ◽

Phosphatidylinositol 3 Kinase ◽

Cisplatin Sensitivity ◽

Phosphatidylinositol 3

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Cell detachment modulates TRAIL resistance in ovarian cancer cells by downregulating the phosphatidylinositol 3-kinase/Akt pathway

International Journal of Gynecological Cancer ◽

10.1111/j.1525-1438.2007.01062.x ◽

2008 ◽

Vol 18 (4) ◽

pp. 670-676 ◽

Author(s):

D. LANE ◽

A. CARTIER ◽

C. RANCOURT ◽

A. PICH

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Akt Pathway ◽

Ovarian Cancer Cells ◽

Cell Detachment ◽

Phosphatidylinositol 3 Kinase ◽

Trail Resistance ◽

Phosphatidylinositol 3

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Phosphatidylinositol 3-kinase Inhibitor (PIK75) Containing Surface Functionalized Nanoemulsion for Enhanced Drug Delivery, Cytotoxicity and Pro-apoptotic Activity in Ovarian Cancer Cells

Pharmaceutical Research ◽

10.1007/s11095-012-0793-6 ◽

2012 ◽

Vol 29 (10) ◽

pp. 2874-2886 ◽

Author(s):

Meghna Talekar ◽

Srinivas Ganta ◽

Amit Singh ◽

Mansoor Amiji ◽

Jackie Kendall ◽

...

Keyword(s):

Ovarian Cancer ◽

Drug Delivery ◽

Cancer Cells ◽

Kinase Inhibitor ◽

Ovarian Cancer Cells ◽

Phosphatidylinositol 3 Kinase ◽

Apoptotic Activity ◽

Phosphatidylinositol 3

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