Abstract 2107: Deregulation of tumor suppressor miRNAs results in Six1 oncogene overexpression in pediatric and adult human cancers

2010 ◽  
Author(s):  
J. Saadi Imam ◽  
Kalyan Buddavarapu ◽  
Jennifer S. Lee-Chang ◽  
Peter Hornsby ◽  
Yidong Chen ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Adult Human ◽  
Human Cancers ◽  
Tumor Suppressor Mirnas

Bifidobacterium longumSuppresses Murine Colorectal Cancer through the Modulation of oncomiRs and Tumor Suppressor miRNAs

2019 ◽  
Vol 71 (4) ◽  
pp. 688-700 ◽  
Author(s):  
Cinderella A. Fahmy ◽  
Amira M. Gamal-Eldeen ◽  
Enas A. El-Hussieny ◽  
Bassem M. Raafat ◽  
Nayra S. Mehanna ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Tumor Suppressor ◽  
Tumor Suppressor Mirnas

scholarly journals TRIM proteins in neuroblastoma

2019 ◽  
Vol 39 (12) ◽  
Author(s):  
Yonghu Xu ◽  
Zihan Zhang ◽  
Guofeng Xu
Keyword(s):  
High Risk ◽  
Tumor Suppressor ◽  
Solid Tumor ◽  
Molecular Mechanisms ◽  
Tumor Suppressor Proteins ◽  
Human Cancers ◽  
Tripartite Motif ◽  
Tumor In Childhood ◽  
Trim Proteins

Abstract Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. Outcome for children with high-risk NB remains unsatisfactory. Accumulating evidence suggests that tripartite motif (TRIM) family proteins express diversely in various human cancers and act as regulators of oncoproteins or tumor suppressor proteins. This review summarizes the TRIM proteins involving in NB and the underlying molecular mechanisms. We expect these new insights will provide important implications for the treatment of NB by targeting TRIM proteins.

Diagnostic, prognostic, and therapeutic value of miR-148b in human cancers

2021 ◽  
Vol 21 ◽  
Author(s):  
Afsane Bahrami ◽  
Gordon A. Ferns
Keyword(s):  
Gene Expression ◽  
Tumor Suppressor ◽  
Noncoding Rna ◽  
Clinical Importance ◽  
Aberrant Expression ◽  
Rna Molecules ◽  
Small Noncoding Rna ◽  
Human Cancers ◽  
Therapeutic Value ◽  
Cancer Types

: MicroRNAs (miRs) is a class of conserved, small, noncoding RNA molecules which modulate gene expression post-transcriptionally. miR-148b is a member of miR-148/152 family generally known to be a tumor suppressor via its affect on different signaling pathways and regulatory genes. Aberrant expression of miR-148b has recently been shown to be responsible for tumorigenesis for several different cancer types. This review discusses the current evidences regarding the involvement of miR-148b expression in human cancers and its potential clinical importance for tumor diagnosis, prognosis, and therapeutics.

Abstract 1572: Dystrophin Is a tumor suppressor in human cancers with myogenic programs

2014 ◽  
Author(s):  
Yuexiang Wang ◽  
Adrian Marino-Enriquez ◽  
Richard Bennett ◽  
Meijun Zhu ◽  
Grant Eilers ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Human Cancers

Candidate tumor suppressor, HCCS-1, is downregulated in human cancers and induces apoptosis in cervical cancer

2002 ◽  
Vol 97 (6) ◽  
pp. 780-786 ◽  
Author(s):  
Tae E. Kim ◽  
Yong W. Kim ◽  
Seung Y. Hwang ◽  
Seung M. Shin ◽  
Jin W. Shin ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Tumor Suppressor ◽  
Candidate Tumor Suppressor ◽  
Human Cancers
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