Abstract PO-115: Defining radiation treatment quality disparities in the COVID-19 Era

Author(s):  
Elizabeth C. Gaudio ◽  
Nariman Ammar ◽  
Daniel V Wakefield ◽  
Maria Pisu ◽  
Arash Shaban-Nejad ◽  
...  
2012 ◽  
Vol 30 (34_suppl) ◽  
pp. 266-266
Author(s):  
Jeffrey Quoc Cao ◽  
Jean-Pierre Bissonnette ◽  
Michael Donald Brundage ◽  
Peter Dunscombe ◽  
John French ◽  
...  

266 Background: Innovative, overarching national, and international strategies for the assurance of safe and high quality radiation treatment (RT) are needed, given the rate of technologic innovation and shifts in traditional roles associated with RT planning and delivery. Methods: The Canadian Partnership for Quality Radiotherapy (CPQR) was created as an interprofessional alliance of the Canadian Association of Radiation Oncology (CARO), Canadian Organization of Medical Physicists (COMP), Canadian Association of Medical Radiation Technologists (CAMRT) and Canadian Partnership Against Cancer (CPAC), aimed at developing and promoting coordinated national strategies for high quality and safe RT. Results: A steering committee of national leaders from each profession and content experts in RT quality and safety was created, with financial and strategic backing provided by the federal government through CPAC. The vision and strategy were communicated broadly to the RT treatment community and to other stakeholders provincially, nationally, and internationally. ‘Quality Assurance Guidance for Canadian Radiation Treatment Programs’ was published online in April 2011 and empowered programs across the country to evaluate their internal procedures against these indicators. This document was downloaded over 875 times in the first 6 months, a measure of the demand and broad uptake in Canada and internationally. This early success has fostered other foci of activity, including engagement by the Canadian medical physics community around synthesis of detailed quality control guidelines for equipment, a dialogue about national incident reporting, and support from international partners in relation to collaborative programs. The goal is to incorporate RT quality and safety indicators into national accreditation programs for cancer care to assure long-term sustainability. Conclusions: CPQR has established a model for quality and safety that is fostering the evolution of a new national quality culture. This model is applicable to other jurisdictions, recognizing that a coordinated international approach to setting guidelines and standards will ultimately lead to higher quality and safer RT on a global scale.


2017 ◽  
Vol 42 ◽  
pp. 17
Author(s):  
Hyojun Park ◽  
Hyun Joon Choi ◽  
Jung-In Kim ◽  
Chul Hee Min

Author(s):  
S. Phyllis Steamer ◽  
Rosemarie L. Devine

The importance of radiation damage to the skin and its vasculature was recognized by the early radiologists. In more recent studies, vascular effects were shown to involve the endothelium as well as the surrounding connective tissue. Microvascular changes in the mouse pinna were studied in vivo and recorded photographically over a period of 12-18 months. Radiation treatment at 110 days of age was total body exposure to either 240 rad fission neutrons or 855 rad 60Co gamma rays. After in vivo observations in control and irradiated mice, animals were sacrificed for examination of changes in vascular fine structure. Vessels were selected from regions of specific interest that had been identified on photomicrographs. Prominent ultrastructural changes can be attributed to aging as well as to radiation treatment. Of principal concern were determinations of ultrastructural changes associated with venous dilatations, segmental arterial stenosis and tortuosities of both veins and arteries, effects that had been identified on the basis of light microscopic observations. Tortuosities and irregularly dilated vein segments were related to both aging and radiation changes but arterial stenosis was observed only in irradiated animals.


Author(s):  
Judy Ju-Hu Chiang ◽  
Robert Kuo-Cheng Chen

Germ cells from the rice stem borer Chilo suppresalis, were examined by light and electron microscopy. Damages to organelles within the germ cells were observed. The mitochondria, which provide the cell with metabolic energy, were seen to disintegrate within the germ cell. Lysosomes within the germ cell were also seen to disintegrate. The subsequent release of hydrolytic enzymesmay be responsible for the destruction of organelles within the germ cell. Insect spermatozoa were seen to lose the ability to move because of radiation treatment. Damage to the centrioles, one of which is in contact with the tail, may be involved in causing sperm immobility.


2017 ◽  
Vol 1 (3) ◽  
pp. 54
Author(s):  
BOUKELLOUZ Wafa ◽  
MOUSSAOUI Abdelouahab

Background: Since the last decades, research have been oriented towards an MRI-alone radiation treatment planning (RTP), where MRI is used as the primary modality for imaging, delineation and dose calculation by assigning to it the needed electron density (ED) information. The idea is to create a computed tomography (CT) image or so-called pseudo-CT from MRI data. In this paper, we review and classify methods for creating pseudo-CT images from MRI data. Each class of methods is explained and a group of works in the literature is presented in detail with statistical performance. We discuss the advantages, drawbacks and limitations of each class of methods. Methods: We classified most recent works in deriving a pseudo-CT from MR images into four classes: segmentation-based, intensity-based, atlas-based and hybrid methods. We based the classification on the general technique applied in the approach. Results: Most of research focused on the brain and the pelvis regions. The mean absolute error (MAE) ranged from 80 HU to 137 HU and from 36.4 HU to 74 HU for the brain and pelvis, respectively. In addition, an interest in the Dixon MR sequence is increasing since it has the advantage of producing multiple contrast images with a single acquisition. Conclusion: Radiation therapy field is emerging towards the generalization of MRI-only RT thanks to the advances in techniques for generation of pseudo-CT images. However, a benchmark is needed to set in common performance metrics to assess the quality of the generated pseudo-CT and judge on the efficiency of a certain method.


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