Abstract PO-120: Need for more sociodemographic data in qualitative childhood cancer research: Findings from a scoping review

Author(s):  
Sarah Burack ◽  
Eric M. Wiedenman ◽  
Melanie Ward ◽  
Lindsay Kaufman ◽  
Thembekile Shato ◽  
...  
2020 ◽  
Vol 16 (7) ◽  
pp. 674-689 ◽  
Author(s):  
Ronald B. Brown

This article presents a scoping review and synthesis of research findings investigating the toxic cellular accumulation of dysregulated inorganic phosphate—phosphate toxicity—as a pathophysiological determinant of diabetes and diabetic complications. Phosphorus, an essential micronutrient, is closely linked to the cellular metabolism of glucose for energy production, and serum inorganic phosphate is often transported into cells along with glucose during insulin therapy. Mitochondrial dysfunction and apoptosis, endoplasmic reticulum stress, neuronal degeneration, and pancreatic cancer are associated with dysregulated levels of phosphate in diabetes. Ectopic calcification involving deposition of calcium-phosphate crystals is prevalent throughout diabetic complications, including vascular calcification, nephropathy, retinopathy, and bone disorders. A low-glycemic, low-phosphate dietary intervention is proposed for further investigations in the treatment and prevention of diabetes and related diabetic pathologies.


2020 ◽  
Author(s):  
Cheng Hang Wu ◽  
Ching Ju Chiu ◽  
Yen Ju Liou ◽  
Chun Ying Lee ◽  
Susan C. Hu

BACKGROUND There is still no consensus on research terms for smart healthcare worldwide. The study conducted by Lewis 10 years ago showed extending geographic access was the major health purpose of health-related information communication technology (ICT), but today's situation may be different because of the rapid development of smart healthcare. Objective: The main aim of this study is to classify recent smart healthcare interventions. Therefore, this scoping review was conducted as a feasible tool for exploring this domain and summarizing related research findings. OBJECTIVE The main aim of this study is to classify recent smart healthcare interventions. Therefore, this scoping review was conducted as a feasible tool for exploring this domain and summarizing related research findings. METHODS The scoping review relies on the analysis of previous reviews of smart healthcare interventions assessed for their effectiveness in the framework of a systematic review and/or meta-analysis. The search strategy was based on the identification of smart healthcare interventions reported as the proposed keywords. In the analysis, the reviews published from January 2015 to December 2019 were included. RESULTS The number of publications for smart healthcare's systematic reviews has continued to grow in the past five years. The search strategy yielded 210 systematic reviews and/or meta-analyses addressed to target groups of interest. 68.5% of these publications used mobile health as a keyword. According to the classification by Lewis, 37.62% of the literature was applied to extend geographic access. According to the classification by the Joint Commission of Taiwan (JCT), 48.84% of smart healthcare was applied in clinical areas, and 60% of it was applied in outpatient medical services. CONCLUSIONS Smart healthcare interventions are being widely used in clinical settings and for disease management. The research of mobile health has received the most attention among smart healthcare interventions. The main purpose of mobile health was used to extend geographic access to increase medical accessibility in clinical areas. CLINICALTRIAL none


2021 ◽  
Vol 270 ◽  
pp. 113657
Author(s):  
S. Namin ◽  
Y. Zhou ◽  
J. Neuner ◽  
K. Beyer

2018 ◽  
Vol 119 (6) ◽  
pp. 771-778 ◽  
Author(s):  
Gerald M. Kendall ◽  
John F. Bithell ◽  
Kathryn J. Bunch ◽  
Gerald J. Draper ◽  
Mary E. Kroll ◽  
...  

2021 ◽  
Author(s):  
Godwin Denk Giebel ◽  
Christian Speckemeier ◽  
Carina Abels ◽  
Kirstin Börchers ◽  
Jürgen Wasem ◽  
...  

BACKGROUND Usage of digital health applications (DHA) is increasing internationally. More and more regulatory bodies develop regulations and guidelines to enable an evidence-based and safe use. In Germany, DHA fulfilling predefined criteria (Digitale Gesundheitsanwendungen (="DiGA")) can be prescribed and are reimbursable by the German statutory health insurance scheme. Due to the increasing distribution of DHA problems and barriers should receive special attention. OBJECTIVE This study aims to identify relevant problems and barriers related to the use of DHA fulfilling the criteria of DiGA. The research done in this area will be mapped and research findings will be summarized. METHODS Conduct of the scoping review will follow published methodological frameworks and PRISMA-Scr criteria. Electronic databases (MEDLINE, EMBASE, and PsycINFO), reference lists of relevant articles and grey literature sources will be searched. Two reviewers will assess eligibility of articles by a two-stage (title/abstract and full-text) screening process. Only problems and barriers related to DHA fulfilling the criteria of DiGA are included for this research. RESULTS This scoping review serves to give an overview about the available evidence and to identify research gaps with regards to problems and barriers related to DiGA. Results are planned to be submitted to an indexed, peer-reviewed journal in the fourth quarter of 2021. CONCLUSIONS This is the first review identifying problems and barriers specifically to the use of the German definition of DiGA. Nevertheless, our findings can presumably be applied to other contexts and health care systems as well.


2017 ◽  
Vol 4 (1) ◽  
pp. 39-48 ◽  
Author(s):  
Carrie A. Blair ◽  
Kelly G. Shaver

Extrinsic and intrinsic motivations are simple concepts that our students seem to quickly understand, yet few of our students grasp the complexity of sustaining intrinsic motivation. This exercise aims to help students better understand that complexity. Students are given a two-part scenario. In Part 1, the individual motives to innovate are intrinsic (e.g., to have societal impact); in Part 2, the individual is faced with realities that constrain the impact of the innovation (e.g., policies to protect idea ownership and profit). The scenario is purposefully based on an important topic unfamiliar to students (childhood cancer research), which provides an opportunity for inductive learning, and keeps student perceptions between Part 1 and Part 2 separate. The exercise allows for discussion of motivation theory, incentives, ethical decision making, and transformational leadership. In advanced entrepreneurship classes the exercise may help students understand intrapreneurship and technology commercialization. The exercise pairs well with Kerr’s classic article, “The folly of rewarding A . . . ,” on the juxtaposition between goals and incentives. Suggestions for an article and video on childhood cancer research are also provided for the instructor to use to increase perceptions of validity of the scenario. Target audiences for this exercise include undergraduate, graduate, and executive groups.


Cancer ◽  
2014 ◽  
Vol 120 (19) ◽  
pp. 3007-3015 ◽  
Author(s):  
Jessica R. B. Musselman ◽  
Logan G. Spector ◽  
Mark D. Krailo ◽  
Gregory H. Reaman ◽  
Amy M. Linabery ◽  
...  

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