Reducing Anastomotic Leakage by Reinforcement of Colorectal Anastomosis with Cyanoacrylate Glue

2013 ◽  
Vol 50 (3-4) ◽  
pp. 255-261 ◽  
Author(s):  
Z. Wu ◽  
K.A. Vakalopoulos ◽  
L.F. Kroese ◽  
G.S.A. Boersema ◽  
G.J. Kleinrensink ◽  
...  
Keyword(s):  
Anastomotic Leakage ◽  
Colorectal Anastomosis ◽  
Cyanoacrylate Glue

A New Anastomotic Leakage Model in Circular Double Stapled Colorectal Anastomosis After Low Anterior Rectum Resection in Pigs

2013 ◽  
Vol 26 (6) ◽  
pp. 364-372 ◽  
Author(s):  
F. A. Wenger ◽  
E. Szucsik ◽  
B. F. Hoinoiu ◽  
M. Ionac ◽  
M. K. Walz ◽  
...  
Keyword(s):  
Anastomotic Leakage ◽  
Colorectal Anastomosis ◽  
Leakage Model ◽  
Rectum Resection

scholarly journals CAN FLUORESCENT ANGIOGRAPHY REDUCE THE LEAK RATE OF COLONIC ANASTOMOSES? (a meta-analysis)

2019 ◽  
Vol 18 (4) ◽  
pp. 139-150
Author(s):  
M. V. Alekseev ◽  
Yu. A. Shelygin ◽  
E. G. Rybakov
Keyword(s):  
Colorectal Surgery ◽  
Anastomotic Leakage ◽  
Fluorescence Imaging ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Randomized Study ◽  
Colorectal Anastomosis ◽  
Original Data ◽  
Fluorescence Angiography ◽  
Rectal Cancer Surgery

AIM: to evaluate of efficacy of fluorescence angiography (FA) in reducing the anastomotic leakage (AL) rate after colorectal surgery in meta-analysis.SEARCH STRATEGY: PubMed were searched up to May 2019 for studies comparing fluorescence imaging with standard approach. The primary outcome measure was colorectal anastomotic leakage (AL) rate. The Newcastle-Ottawa scale was used for quality assessment. A meta-analysis with random-effects model was performed to calculate odds ratios (ORs) from the original data.RESULTS: Two thousand four hundred and sixty-six patients from 7 non-randomized studies and 1 randomized study were included. Fluorescence imaging significantly reduced the AL rate in patients after colorectal surgery (OR 0.58; 95%CI 0.39-0.85; p=0.006) and after rectal cancer surgery (OR 0.28; 95%CI, 0.14-0.55; p=0.0002). A limitation of this meta-analysis is the inclusion of only one randomized study.CONCLUSION: Fluorescence angiography with indocyanine green is a method of preventing of leakage of colorectal anastomosis. The results of randomized clinical trials are needed to confirm the effectiveness of this technique.

Colorectal anastomosis in rectal cancer surgery: methods of anastomotic leakage prevention

2021 ◽  
Vol 11 (2) ◽  
pp. 36-43
Author(s):  
S. G. Gaydarov ◽  
Z Z Mamedli ◽  
M. S. Lebedko ◽  
V. Yu. Selchuk ◽  
I. Sh. Tataev
Keyword(s):  
Risk Factors ◽  
Anastomotic Leakage ◽  
Surgical Complication ◽  
Treatment Options ◽  
Colorectal Anastomosis ◽  
Review Article ◽  
Rectal Cancer Surgery ◽  
Complication Rates ◽  
Preoperative Period ◽  
Minimum Risk

One of the most serious complications after low anterior resection is the failure of sutures of colorectal anastomosis, which is the most common surgical complication that results in patient’s death. Promptly diagnosed anastomotic leakage in postoperative period is challenging. Nevertheless, elimination of risk factors in preoperative period can significantly reduce complication rates.The purpose of this review article is to analyze possible risk factors and methods for preventing colorectal anastomosis leakage.An important area of prevention and optimization of treatment options for anastomotic leakage is the development of prognostic measures to eliminate risk factors. We see the prospects for this direction in the introduction of a nomogram, which allows the surgeon to assess the possible outcomes of the operation, to choose the optimal tactics with a minimum risk of complications, as well as the introduction of methods to avoid or prevent the development of complications of colorectal anastomosis.

scholarly journals THE ROLE OF NEUTROPHIL-TO-LYMPHOCYTE RATIO (NLR) IN THE DIAGNOSIS OF LOW COLORECTAL ANASTOMOSIS LEAKAGE

2017 ◽  
pp. 74-81 ◽  
Author(s):  
Yu. A. Shelygin ◽  
M. A. Tarasov ◽  
I. V. Zarodnyuk ◽  
M. A. Nagudov ◽  
M. V. Alekseev ◽  
...  
Keyword(s):  
Anastomotic Leakage ◽  
Colorectal Anastomosis ◽  
Clinical Manifestations ◽  
Diagnostic Value ◽  
T Test ◽  
Surgical Interventions ◽  
X Ray ◽  
Anastomosis Leakage ◽  
Sensitivity Specificity

Anastomotic leakage (AL) following surgical interventions associated with total mesorectal excision (TME) and formation of fistula is the most common and dangerous complication of this kind of intervention, its incidence is 17 %. OBJECTIVE. Determine diagnostic value of Neutrophil-to-Lymphocyte Rato (NLR) in the diagnosis of low colorectal anastomosis leakage after low anterior resection (LAR). Patients and methods: 100 patients with epithelial tumors of rectum in the period 2013-2016 yy underwent surgery - LAR with colorectal anastomosis and preventive stoma. In patients without clinical symptomsrent genological study was performed in order to identify asymptomatic AL on day 7 after the surgery. An incidence of AL, difference in the levels of NLR in patients with AL and consistent anastomosis, we also assessed sensitivity, specificity, positive (PPV) and negative predictive value (NPV) of these markers. RESULTS. AL was diagnosed in 20 % (20/100): in 11 % (11/100) with clinical manifestations, in 9 % (9/100) - without them (contrast leakage according to X-ray examination). In the group of patients with anastomotic leakage, the median of NLR differed from that in patients without compromised integrity of anastomosis at both postoperative day 3 (7,1 vs 5,7, respectively, ((t-test) p=0,042) and postoperative day 6 (6,8 vs 4.4, respectively, ((t-test) p=0,004). Conclusion: an incidence of anastomotic leakage was 20 %, but only 11 % of the patients had clinical manifestations. Changes in the level of NLR in the postoperative period correlated with the fact of AL.

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