Intravascular Hemolysis, Vascular Endothelial Cell Activation and Thrombophilia in Splenectomized Patients with Hemoglobin E/β-Thalassemia Disease

2014 ◽  
Vol 132 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Vichai Atichartakarn ◽  
Suporn Chuncharunee ◽  
Napaporn Archararit ◽  
Umaporn Udomsubpayakul ◽  
Katcharin Aryurachai
2008 ◽  
Vol 57 (4) ◽  
pp. 441-446 ◽  
Author(s):  
R. Morchón ◽  
A. Rodríguez-Barbero ◽  
S. Velasco ◽  
J. López-Belmonte ◽  
F. Simón

Blood ◽  
2013 ◽  
Vol 122 (10) ◽  
pp. 1833-1842 ◽  
Author(s):  
Sarah Bruneau ◽  
Hironao Nakayama ◽  
Craig B. Woda ◽  
Evelyn A. Flynn ◽  
David M. Briscoe

Key Points DEPTOR is expressed in vascular endothelial cells and serves as an endogenous inhibitor of mTORC1, ERK1/2, and STAT1 activity. DEPTOR is potent to regulate endothelial cell expression of chemokines and adhesion molecules, leukocyte-endothelial adhesion, and endothelial migratory responses.


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