scholarly journals Influence of Chronic Kidney Disease on Physical Function and Quality of Life in Patients after Coronary Artery Bypass Grafting

2015 ◽  
Vol 5 (4) ◽  
pp. 237-245 ◽  
Author(s):  
Yueh-Ting Kuo ◽  
Kuan-Ming Chiu ◽  
Yuk-Ming Tsang ◽  
Cheng-Ming Chiu ◽  
Meng-Yueh Chien

Aims: The purposes of this study were (1) to compare body composition, physical function, and quality of life (QOL) between patients after coronary artery bypass grafting (CABG) with and without chronic kidney disease (CKD) and (2) to analyze the factors associated with physical function and QOL domains in these patients. Methods: Thirty male post-CABG patients with CKD and 30 matched controls were recruited. All subjects underwent dual-energy X-ray absorptiometry for body composition evaluation. Physical function tests included the grip strength test, 30-second chair stand test (30CST), and 6-min walk test (6MWT). Physical activity and QOL were assessed using the long form of the International Physical Activity Questionnaire and the World Health Organization Quality of Life Instrument (WHOQOL)-BREF, respectively. Results: Post-CABG patients with CKD exhibited a lower arm lean mass and higher percent leg fat mass than those without CKD (p < 0.05). The patients with CKD also had lower 30CST scores, 6MWT distances, and QOL domain of social relationships scores than those without CKD after adjusting for covariates (p < 0.05). If NYHA class was considered in the model, NYHA class became the most important factor associated with 6MWT distances (β = -0.647, p < 0.001) and the QOL domains of psychological health (β = -0.285, p = 0.027) and environment (β = -0.406, p = 0.001). Conclusion: Post-CABG patients with CKD had worse body composition, physical function, and QOL than those without CKD, and this might be associated with a worse NYHA class.

2021 ◽  
Vol 8 ◽  
pp. 205435812098705
Author(s):  
Kathryn Wytsma-Fisher ◽  
Stefan Mustata ◽  
Theresa Cowan ◽  
Manuel Ester ◽  
S. Nicole Culos-Reed

Background: Low physical activity levels and poor physical functioning are strongly associated with poor clinical outcomes and mortality in adult kidney failure patients, regardless of treatment modality. Compared with the general population, individuals with chronic kidney disease are physically inactive, have reduced physical abilities and difficulties performing routine daily tasks, lower health-related quality of life, and higher cardiovascular morbidity and mortality. In addition, frail kidney failure patients have higher hospitalization and mortality rates as compared with other kidney failure patients. Evidence suggests that assessment and recommendations for physical activity should be part of standard care for kidney failure patients. Structured exercise can improve physical function and quality of life in frail older adults and may be used specifically for management of frailty in kidney failure. However, research is needed to determine best practices for implementation of physical function measurements and physical activity promotion in standard kidney failure care. Objective: The proposed Move More study will assess the feasibility of a physical activity intervention offered to the kidney failure inpatients in Calgary, Alberta. Specifically, this study is designed to examine the effects of an early physical activity/mobility intervention led by a kinesiologist, and supported by the clinical care team including physiotherapists (PT) and nurse clinicians. Methods: The Move More study is a single-arm pilot intervention examining feasibility and optimal improvement in real-world conditions. Kidney failure inpatients at the Foothills Medical Centre will be recruited to participate. Patients will receive an individualized in-hospital physical activity/mobility intervention. Frailty and physical function will be assessed at baseline and postintervention prior to hospital discharge. The goal is to recruit 24 to 36 patients. Conclusions: Evidence needed to support the inclusion of mobility and physical activity as part of standard care will be gathered, with knowledge gained used to help direct future physical activity programming for kidney failure inpatients.


2000 ◽  
Vol 9 (1) ◽  
pp. 52-63 ◽  
Author(s):  
Johan Herlitz ◽  
Kenneth Caidahl ◽  
Ingela Wiklund ◽  
Helén Sjöland ◽  
Björn Karlson ◽  
...  

2004 ◽  
Vol 3 (1) ◽  
pp. 82-83
Author(s):  
D. Pistolas ◽  
V. Papagianaki ◽  
A. Balaska ◽  
E. Stamatopoulou ◽  
A. Ouzounidou ◽  
...  

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
L Iliuta

Abstract Aim 1. To evaluate whether a supervised cardiac rehabilitation (CR) program improves physical capacity and quality of life (QoL) of patients with LV systolic dysfunction undergoing coronary artery bypass grafting (CABG) compared to patients training by their own. 2. To investigate LV diastolic function dynamics according to the results of tissue Doppler imaging (TDI) in these patients. 3. To define the echographic predictors for long term prognosis in these patients and their adjusted value for calculation of a preoperative risk score. Material and method Prospective randomized study on 665 CABG patients with LV systolic dysfunction (LVEF<35%), comparing 12 weeks of supervised exercise training (SET) 3 times per week to home-based training based upon public health recommendations of minimum level of physical activity. Patients were evaluated including TDI preoperatively and till 5 years postoperatively. The primary endpoints were the composites of death from any cause or hospitalization for cardiac causes and the secondary endpoints were changes in peak oxygen uptake and in physical capacity (measured with cardiopulmonary exercise testing), changes in health-related QoL and changes in physical activity level (measured with International Physical Activity Questionnary). Stastistical analysis used SYSTAT and SPSS programs. Results 1. SET was more efficient in rehabilitating CABG patients being an independent predictor for a more favourable postoperative evolution, mostly in patients with normal LV diastolic filling pattern (LVDFP) (97,27%) compared with restrictive LV filling (89.83%). At 5 years postoperatively, cardiovascular event-free survival was significantly higher in nonrestrictive LVDFP group (74.94%) compared with restrictive LVDFP (55,75%). 2. Conventional transmitral diastolic Doppler indices before and after CABG remained unchanged. TDI showed significant improvement in SET group at 3 and 12 months postoperatively of both LV systolic (S: 6.1±0.9, 7.5±1.1 and 7.3±1.2cm/s) and diastolic function (e': 7.2±1.8, 8.3±1.4 and 8.8±1.5cm/s.; E/e' ratio: 17.8±2.1, 13.1±1.7 and 11.3±1.8; Vp 3.2±0.55, 2.4±0.28 and 1.9±0.26) 3. The main predictors for unfavorable evolution at 5 years postoperatively were: age >75 years (RR=7.3), LV end-systolic volume (LVESV) >85cm3 (RR=6.4), restrictive LVDFP (RR=8.9) and pulmonary hypertension (PHT) (RR=5.2). Conclusions 1. SET improves physical capacity and QoL in CABG patients, mainly in those with normal LVDFP, the restrictive LVDFP being associated with an early and late postoperative unfavourable evolution and difficult CR. 2. Exercise capacity and symptoms are more closely correlated with indices assessed by TDI which demonstrate significant improvement of LV systolic and diastolic function in SET patients, regardless of transmitral flow pattern 3. On long term postoperatively the unfavorable evolution was predicted by: age>75 years, LVESV>85cm3, restrictive LVDFP and severe PHT.


2019 ◽  
Vol 108 (3) ◽  
pp. 764-769 ◽  
Author(s):  
Marina Macedo Kuenzer Bond ◽  
Jenny Lourdes Rivas de Oliveira ◽  
Pedro Silvio Farsky ◽  
Vivian Lerner Amato ◽  
Arturo Adrian Jara ◽  
...  

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