Notch4 Signaling Pathway of Endothelial Progenitor Cells in a Kawasaki Disease Model Induced by Lactobacillus casei Cell Wall Extract

2016 ◽  
Vol 53 (5-6) ◽  
pp. 340-348
Author(s):  
Huafeng Wang ◽  
Yuanyuan Xia ◽  
Songling Fu ◽  
Wei Wang ◽  
Chunhong Xie ◽  
...  
2017 ◽  
Vol 13 (6) ◽  
pp. 3438-3442
Author(s):  
Lichao Gao ◽  
Songling Fu ◽  
Wei Wang ◽  
Chunhong Xie ◽  
Yiying Zhang ◽  
...  

2014 ◽  
Vol 400 (1-2) ◽  
pp. 201-206 ◽  
Author(s):  
Ferry Sandra ◽  
Yudi Her Oktaviono ◽  
Mohammad Aris Widodo ◽  
Yanni Dirgantara ◽  
Angliana Chouw ◽  
...  

Marine Drugs ◽  
2019 ◽  
Vol 17 (7) ◽  
pp. 392
Author(s):  
Vinoth Kumar Rethineswaran ◽  
Yeon-Ju Kim ◽  
Woong Bi Jang ◽  
Seung Taek Ji ◽  
Songhwa Kang ◽  
...  

The purpose of the present study is to improve the endothelial progenitor cells (EPC) activation, proliferation, and angiogenesis using enzyme-aided extraction of fucoidan by amyloglucosidase (EAEF-AMG). Enzyme-aided extraction of fucoidan by AMG (EAEF-AMG) significantly increased EPC proliferation by reducing the reactive oxygen species (ROS) and decreasing apoptosis. Notably, EAEF-AMG treated EPCs repressed the colocalization of TSC2/LAMP1 and promoted perinuclear localization of mTOR/LAMP1 and mTOR/Rheb. Moreover, EAEF-AMG enhanced EPC functionalities, including tube formation, cell migration, and wound healing via regulation of AKT/Rheb signaling. Our data provided cell priming protocols to enhance therapeutic applications of EPCs using bioactive compounds for the treatment of CVD.


2009 ◽  
Vol 98 (8) ◽  
pp. 1355-1359 ◽  
Author(s):  
Xiao-qin Liu ◽  
Guo-ying Huang ◽  
Xue-cun Liang ◽  
Xiao-jing Ma

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