Consequences of Stimulus Type on Higher-Order Processing in Single-Sided Deaf Cochlear Implant Users

2016 ◽  
Vol 21 (5) ◽  
pp. 305-315 ◽  
Author(s):  
Mareike Finke ◽  
Pascale Sandmann ◽  
Hanna Bönitz ◽  
Andrej Kral ◽  
Andreas Büchner
Keyword(s):  
Cochlear Implant ◽  
Auditory Processing ◽  
Cognitive Abilities ◽  
Speech Intelligibility ◽  
Higher Order ◽  
Central Auditory Processing ◽  
Order Processing ◽  
Objective Evidence ◽  
Word Classification ◽  
Related Potentials

Single-sided deaf subjects with a cochlear implant (CI) provide the unique opportunity to compare central auditory processing of the electrical input (CI ear) and the acoustic input (normal-hearing, NH, ear) within the same individual. In these individuals, sensory processing differs between their two ears, while cognitive abilities are the same irrespectively of the sensory input. To better understand perceptual-cognitive factors modulating speech intelligibility with a CI, this electroencephalography study examined the central-auditory processing of words, the cognitive abilities, and the speech intelligibility in 10 postlingually single-sided deaf CI users. We found lower hit rates and prolonged response times for word classification during an oddball task for the CI ear when compared with the NH ear. Also, event-related potentials reflecting sensory (N1) and higher-order processing (N2/N4) were prolonged for word classification (targets versus nontargets) with the CI ear compared with the NH ear. Our results suggest that speech processing via the CI ear and the NH ear differs both at sensory (N1) and cognitive (N2/N4) processing stages, thereby affecting the behavioral performance for speech discrimination. These results provide objective evidence for cognition to be a key factor for speech perception under adverse listening conditions, such as the degraded speech signal provided from the CI.

scholarly journals Logatome Discrimination in Cochlear Implant Users: Subjective Tests Compared to the Mismatch Negativity

2010 ◽  
Vol 10 ◽  
pp. 329-339 ◽  
Author(s):  
Torsten Rahne ◽  
Michael Ziese ◽  
Dorothea Rostalski ◽  
Roland Mühler
Keyword(s):  
Speech Perception ◽  
Cochlear Implant ◽  
Mismatch Negativity ◽  
Speech Intelligibility ◽  
Event Related Potentials ◽  
Normal Hearing ◽  
Discrimination Test ◽  
Speech Database ◽  
Automated Speech Recognition ◽  
Related Potentials

This paper describes a logatome discrimination test for the assessment of speech perception in cochlear implant users (CI users), based on a multilingual speech database, the Oldenburg Logatome Corpus, which was originally recorded for the comparison of human and automated speech recognition. The logatome discrimination task is based on the presentation of 100 logatome pairs (i.e., nonsense syllables) with balanced representations of alternating “vowel-replacement” and “consonant-replacement” paradigms in order to assess phoneme confusions. Thirteen adult normal hearing listeners and eight adult CI users, including both good and poor performers, were included in the study and completed the test after their speech intelligibility abilities were evaluated with an established sentence test in noise. Furthermore, the discrimination abilities were measured electrophysiologically by recording the mismatch negativity (MMN) as a component of auditory event-related potentials. The results show a clear MMN response only for normal hearing listeners and CI users with good performance, correlating with their logatome discrimination abilities. Higher discrimination scores for vowel-replacement paradigms than for the consonant-replacement paradigms were found. We conclude that the logatome discrimination test is well suited to monitor the speech perception skills of CI users. Due to the large number of available spoken logatome items, the Oldenburg Logatome Corpus appears to provide a useful and powerful basis for further development of speech perception tests for CI users.

Central Auditory Processing

2021 ◽  
Author(s):  
Josef P. Rauschecker
Keyword(s):  
Auditory Cortex ◽  
Auditory Processing ◽  
Cognitive Abilities ◽  
Auditory Perception ◽  
Auditory Brainstem ◽  
Central Auditory Processing ◽  
Visible Part ◽  
Auditory Object ◽  
Mother’S Voice ◽  
The Brain

When one talks about hearing, some may first imagine the auricle (or external ear), which is the only visible part of the auditory system in humans and other mammals. Its shape and size vary among people, but it does not tell us much about a person’s abilities to hear (except perhaps their ability to localize sounds in space, where the shape of the auricle plays a certain role). Most of what is used for hearing is inside the head, particularly in the brain. The inner ear transforms mechanical vibrations into electrical signals; then the auditory nerve sends these signals into the brainstem, where intricate preprocessing occurs. Although auditory brainstem mechanisms are an important part of central auditory processing, it is the processing taking place in the cerebral cortex (with the thalamus as the mediator), which enables auditory perception and cognition. Human speech and the appreciation of music can hardly be imagined without a complex cortical network of specialized regions, each contributing different aspects of auditory cognitive abilities. During the evolution of these abilities in higher vertebrates, especially birds and mammals, the cortex played a crucial role, so a great deal of what is referred to as central auditory processing happens there. Whether it is the recognition of one’s mother’s voice, listening to Pavarotti singing or Yo-Yo Ma playing the cello, hearing or reading Shakespeare’s sonnets, it will evoke electrical vibrations in the auditory cortex, but it does not end there. Large parts of frontal and parietal cortex receive auditory signals originating in auditory cortex, forming processing streams for auditory object recognition and auditory-motor control, before being channeled into other parts of the brain for comprehension and enjoyment.

scholarly journals Event related potentials in cases of amblyaudia

2020 ◽  
Vol 6 (4) ◽  
pp. 747
Author(s):  
Wessam Mostafa Essawy
Keyword(s):  
Auditory Processing ◽  
Event Related Potentials ◽  
Speech Development ◽  
Screening Tests ◽  
Control Group ◽  
Auditory Information ◽  
Central Auditory Processing ◽  
Auditory Processing Disorders ◽  
Central Auditory Processing Disorders ◽  
Related Potentials

<p class="abstract"><strong>Background:</strong> Amblyaudia is a weakness in the listener’s binaural processing of auditory information. Subjects with amblyaudia also demonstrate binaural integration deficits and may display similar patterns in their evoked responses in terms of latency and amplitude of these responses. The purpose of this study was to identify the presence of amblyaudia in a population of young children subjects and to measure mismatch negativity (MMN), P300 and cortical auditory evoked potentials (CAEPs) for those individuals.</p><p class="abstract"><strong>Methods:</strong> Subjects included in this study were divided into 2 groups control group that consisted of 20 normal hearing subjects with normal developmental milestones and normal speech development. The study group (GII) consisted of 50 subjects with central auditory processing disorders (CAPDs) diagnosed by central auditory screening tests. </p><p class="abstract"><strong>Results:</strong> With using dichotic tests including dichotic digits test (DDT) and competing sentence test (CST), we could classify these cases into normal, dichotic dysaudia, amblyaudia, and amblyaudia plus with percentages (40%, 14%, 38%, 8% respectively). Using event related potentials, we found that P300 and MMN are more specific in detecting neurocognitive dysfunction related to allocation of attentional resources and immediate memory in these cases.</p><p class="abstract"><strong>Conclusions:</strong> The presence of amblyaudia in cases of central auditory processing disorders (CAPDs) and event related potentials is an objective tool for diagnosis, prognosis and follow up after rehabilitation.</p>

scholarly journals P3 Cognitive Potential in Cochlear Implant Users

2018 ◽  
Vol 22 (04) ◽  
pp. 408-414 ◽  
Author(s):  
Signe Grasel ◽  
Mario Greters ◽  
Maria Goffi-Gomez ◽  
Roseli Bittar ◽  
Raimar Weber ◽  
...  
Keyword(s):  
Speech Recognition ◽  
Cochlear Implant ◽  
Auditory Processing ◽  
Evoked Potential ◽  
Control Group ◽  
Central Auditory Processing ◽  
Speech Discrimination ◽  
Significant Difference ◽  
Cortical Responses ◽  
Peripheral Auditory System

Introduction The P3 cognitive evoked potential is recorded when a subject correctly identifies, evaluates and processes two different auditory stimuli. Objective to evaluate the latency and amplitude of the P3 evoked potential in 26 cochlear implant users with post-lingual deafness with good or poor speech recognition scores as compared with normal hearing subjects matched for age and educational level. Methods In this prospective cohort study, auditory cortical responses were recorded from 26 post-lingual deaf adult cochlear implant users (19 with good and 7 with poor speech recognition scores) and 26 control subjects. Results There was a significant difference in the P3 latency between cochlear implant users with poor speech recognition scores (G-) and their control group (CG) (p = 0.04), and between G- and cochlear implant users with good speech discrimination (G+) (p = 0.01). We found no significant difference in the P3 latency between the CG and G+. In this study, all G- patients had deafness due to meningitis, which suggests that higher auditory function was impaired too. Conclusion Post-lingual deaf adult cochlear implant users in the G- group had prolonged P3 latencies as compared with the CG and the cochlear implant users in the G+ group. The amplitudes were similar between patients and controls. All G- subjects were deaf due to meningitis. These findings suggest that meningitis may have deleterious effects not only on the peripheral auditory system but on the central auditory processing as well.

scholarly journals Central Auditory Processing of Temporal and Spectral-Variance Cues in Cochlear Implant Listeners

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0132423
Author(s):  
Carol Q. Pham ◽  
Peter Bremen ◽  
Weidong Shen ◽  
Shi-Ming Yang ◽  
John C. Middlebrooks ◽  
...  
Keyword(s):  
Cochlear Implant ◽  
Auditory Processing ◽  
Central Auditory Processing ◽  
Spectral Variance

Effect of quetiapine on cognitive function in schizophrenia: a mismatch negativity potentials study

2009 ◽  
Vol 21 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Guo-zhen Yuan ◽  
Zhen-he Zhou ◽  
Jian-jun Yao
Keyword(s):  
Auditory Processing ◽  
Mismatch Negativity ◽  
Event Related Potentials ◽  
Stimulus Onset ◽  
Least Square ◽  
Repeated Measure ◽  
Objective Evidence ◽  
Main Effect ◽  
Related Potentials ◽  
Measure Analysis

Objective:The purpose of this study was to investigate whether the effects of quetiapine on abnormalities of early auditory processing in patients with schizophrenia were reflected by mismatch negativity (MMN).Methods:Subjects were 23 patients with schizophrenia and 23 controls. Psychopathology was rated in patients with the Positive and Negative Syndrome Scale (PANSS) at baseline and after 4-week and after 8-week treatments with quetiapine. Auditory stimuli for event-related potentials consisted of 100 ms/1000 Hz standards, intermixed with 100 ms/1500 Hz frequency deviants and 250 ms/ 1000 Hz duration deviants. A stimulus onset asynchrony of each was 300 ms. Electroencephalograph was recorded at Fz. BESA 5.1.8 was used to perform data analysis. MMN waveforms were obtained by subtracting waveforms elicited by standards from those elicited by frequency- or duration-deviant stimuli.Results:Quetiapine decreased all PANSS scores. Patients showed smaller mean amplitudes of frequency and duration MMN at baseline than did controls. A repeated measure analysis of variance with sessions (i.e. baseline and 4- and 8-week treatments) and MMN type (frequency versus duration) as within-subject factors revealed no significant MMN type or MMN type × session main effect for MMN amplitudes (for MMN type: F = 0.704, df = 1, p = 0.403; for MMN type × session: F = 0.299, df = 2, p = 0.796). Session main effect was significant (F = 3.576, df = 2, p = 0.031). Least square difference tests showed significant differences between MMN amplitudes at 8 weeks and those at both baseline (p = 0.025) and 4 weeks (p = 0.020). MMN amplitudes at 8 weeks were higher than those at baseline.Conclusions:Quetiapine improved the amplitudes of MMN after the 8-week treatment. MMN offers objective evidence that treatment with the quetiapine may ameliorate preattentive deficits in schizophrenia.

scholarly journals Electrophysiological Evidence of Auditory and Cognitive Processing Deficits in Parkinson Disease

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Robert L. Folmer ◽  
Jay J. Vachhani ◽  
Amy Riggins
Keyword(s):  
Cognitive Processing ◽  
Auditory Processing ◽  
Matched Control ◽  
Early Stage ◽  
Verbal Learning ◽  
Event Related Potentials ◽  
Central Auditory Processing ◽  
Control Subjects ◽  
Increased Risk ◽  
Related Potentials

Background. Parkinson’s disease (PD) patients are at increased risk for central auditory processing (CAP) deficits and cognitive dysfunction. However, behavioral assessments of CAP and cognitive processing used in a previous study by our research team found few significant differences in performance between early-stage PD patients and age-matched control subjects. The objective of this study is to use auditory event-related potentials (AERPs) to compare CAP and cognitive functions in a population of PD patients with a group of age-matched control subjects. Methods. AERPs in response to tonal and speech stimuli were recorded from 35 adults who had a medical diagnosis of PD (23 males and 12 females; mean   age = 66.9 ± s . d . 11.2   years ), and 35 age-matched control subjects who did not have PD or any other neurological disorders (31 males and 4 females; mean   age = 65.4 ± s . d . 12.3   years ). Auditory stimuli included pure tones (500 and 1000 Hz) to elicit the P300 response and a dichotic digits paradigm to elicit the N200 processing negativity. Results. Compared to control subjects, PD patients exhibited significantly longer latencies of P300 and N200 components and smaller amplitude N200 components. Latency and amplitude of the N200 component were significantly correlated with participants’ age. N200 amplitude was correlated with results from the Rey Auditory Verbal Learning Test (RAVLT) of cognitive ability. Latency of the P300 and amplitude of the N200 components were significantly correlated with results from the Spatial Release From Masking (SRM) behavioral CAP assessment. Conclusions. AERP assessments used in this study appear to be sensitive indicators of CAP and cognitive deficits exhibited by early-stage PD patients. While few significant differences in performance on behavioral CAP and cognitive tests were previously observed between this population of PD patients and age-matched control subjects, N200 and P300 components recorded in the present study revealed impaired neural processing by the PD group.

Auditory Evoked Potentials and Cochlear Implants: Research Findings and Clinical Applications in Children

2009 ◽  
Vol 19 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Suzanne C Purdy ◽  
Kirsty Gardner-Berry
Keyword(s):  
Cochlear Implant ◽  
Evoked Potentials ◽  
Auditory Processing ◽  
Auditory Evoked Potentials ◽  
Field Research ◽  
Auditory Brainstem ◽  
Clinical Applications ◽  
Central Auditory Processing ◽  
Hearing Sensitivity ◽  
Before And After

Abstract Auditory evoked potentials can be used to objectively assess hearing sensitivity, central auditory processing, and neural encoding of speech sounds up to the level of the auditory cortex. Evoked potentials have been of interest to clinicians and researchers in the cochlear implant field for a long time because of their potential for objectively predicting cochlear implant outcomes, as well as improving candidacy determination, and implant programming. Neural response telemetry and intra-operative electrical auditory brainstem recording have been routinely performed by implant programs for many years. Recently, there has been great interest in potential clinical applications of cortical auditory evoked potentials in the implant field. Research and clinical applications are reviewed and case studies are presented that illustrate clinical applications of cortical evoked potentials in children before and after implantation.

scholarly journals The Important Role of Contextual Information in Speech Perception in Cochlear Implant Users and Its Consequences in Speech Tests

2019 ◽  
Vol 23 ◽  
pp. 233121651983867 ◽  
Author(s):  
J. Gertjan Dingemanse ◽  
André Goedegebure
Keyword(s):  
Working Memory ◽  
Cochlear Implant ◽  
Cognitive Abilities ◽  
Speech Intelligibility ◽  
Contextual Information ◽  
Working Memory Capacity ◽  
Verbal Working Memory ◽  
Memory Capacity ◽  
Use Context

This study investigated the role of contextual information in speech intelligibility, the influence of verbal working memory on the use of contextual information, and the suitability of an ecologically valid sentence test containing contextual information, compared with a CNC (Consonant-Nucleus-Consonant) word test, in cochlear implant (CI) users. Speech intelligibility performance was assessed in 50 postlingual adult CI users on sentence lists and on CNC word lists. Results were compared with a normal-hearing (NH) group. The influence of contextual information was calculated from three different context models. Working memory capacity was measured with a Reading Span Test. CI recipients made significantly more use of contextual information in recognition of CNC words and sentences than NH listeners. Their use of contextual information in sentences was related to verbal working memory capacity but not to age, indicating that the ability to use context is dependent on cognitive abilities, regardless of age. The presence of context in sentences enhanced the sensitivity to differences in sensory bottom-up information but also increased the risk of a ceiling effect. A sentence test appeared to be suitable in CI users if word scoring is used and noise is added for the best performers.

Sign in / Sign up

Export Citation Format

Share Document